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Released: 31-Jan-2019 12:05 PM EST
Does Intensive Blood Pressure Control Reduce Dementia?
University of Alabama at Birmingham

Intensive control of blood pressure in older people significantly reduced the risk of developing mild cognitive impairment, a precursor of early dementia, according to the National Institutes of Health-supported Systolic Blood Pressure Intervention Trial Memory and Cognition in Decreased Hypertension, or SPRINT MIND.

Released: 31-Jan-2019 10:05 AM EST
Ultrasound helps predict successful fistula formation for kidney dialysis patients
University of Alabama at Birmingham

Three ultrasound measurements moderately, but significantly, predict successful arteriovenous fistula maturation. Mature fistulas are vital for hemodialysis, but half fail to mature. This information can facilitate decisions by the clinician, like new surgery or abandonment of the fistula.

Released: 30-Jan-2019 3:05 PM EST
Difference in Brain Connectivity May Explain Autism Spectrum Disorder
University of Alabama at Birmingham

Researchers find brain overconnectivity in the unimodal-subcortical connections and brain underconnectivity in the supramodal-subcortical connections for ASD individuals, as compared to a typically developing control group, suggesting a relationship between connectivity and the expression of ASD.

26-Jan-2019 8:05 AM EST
Transplanting Pig Hearts Into Sick Babies May Be a Promising Temporary Treatment Option
University of Alabama at Birmingham

Pig heart transplants could potentially save the lives of infants with life-threatening heart diseases.

Released: 24-Jan-2019 5:05 PM EST
New master’s degree in anatomy offered, and classes begin in June
University of Alabama at Birmingham

The University of Alabama at Birmingham will launch a new master’s degree in anatomical science this summer to help meet the growing need for anatomists in health care programs and courses.

   
Released: 24-Jan-2019 11:05 AM EST
Kidney-resident macrophages — a role for healing during acute kidney injury?
University of Alabama at Birmingham

Researchers have found that, during acute kidney injury in a mouse model, the kidney-resident macrophages are reprogrammed to a developmental state, resembling these same cells when they are found in newborn mice. This reprogramming may be important to promote healing and tissue regeneration.

Released: 23-Jan-2019 5:30 PM EST
New findings may help oncologists determine effectiveness of checkpoint inhibitors
University of Alabama at Birmingham

In an article recently published in JCI Insight, researchers from the University of Alabama at Birmingham and Vanderbilt University have identified checkpoint inhibitor resistance mechanisms in many solid tumor cancers, including melanoma, lung cancer and breast cancer.

Released: 23-Jan-2019 3:05 PM EST
Researchers discover new biomarker for age-related macular degeneration
University of Alabama at Birmingham

This is the first visual function for incident AMD in older adults with normal macular health and early AMD. Older adults with delayed dark adaptation have a heightened risk for developing AMD within the next few years. Vision in bright light was known to be relatively preserved late into the disease. Night vision is affected much earlier.

Released: 17-Jan-2019 10:15 AM EST
Child survivors of Hodgkin lymphoma have increased risk of second cancer
University of Alabama at Birmingham

Survivors of childhood Hodgkin lymphoma are at an increased risk of developing an entirely new cancer later in life, according to new research published in Cancer — the American Cancer Society’s international peer-reviewed scientific journal — and conducted at University of Alabama at Birmingham.

Released: 10-Jan-2019 5:05 PM EST
Activated PMN exosomes are pathogenic entities that cause destruction in the COPD lung
University of Alabama at Birmingham

Researchers have found a novel, pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in lungs of patients with COPD. These exosomes from activated neutrophils caused COPD damage when they were instilled into the lungs of healthy mice.

Released: 8-Jan-2019 5:05 PM EST
Mechanism for impaired allergic inflammation in infants may explain hygiene hypothesis
University of Alabama at Birmingham

Research published in Immunity describes a mechanism in a mouse model of asthma that supports the hygiene hypothesis — researchers found that infant mice need a higher exposure to a bacterial endotoxin, compared to adult mice, to avoid developing asthma-like reactions to house dust mites.

Released: 8-Jan-2019 2:05 PM EST
Obesity surgery leads to emergence of new microbial strains in the human fecal community
University of Alabama at Birmingham

Using a unique bioinformatics technique developed at UAB, researchers have detected the emergence of new strains of microbes in the human fecal microbiota after obesity surgery. These new strains emerged after surgical disruption of the stomach and upper small intestine.

2-Jan-2019 10:05 AM EST
Does Your Insurance Card Matter When You Have a Heart Attack?
University of Alabama at Birmingham

Investigators from UAB have summarized the impact of the reimbursement gap between Medicaid and private insurance on management and in-hospital outcomes among patients admitted for STEMI.

Released: 3-Jan-2019 11:05 AM EST
UAB outsources its revenue-producing antibodies to the Birmingham company SouthernBiotech
University of Alabama at Birmingham

In a move to maintain revenue and expand opportunities to produce and license new monoclonal antibodies, UAB has outsourced its selection of marketable monoclonal immunoreagents and hybridomas — the cells that produce monoclonal antibodies — to the Birmingham-based SouthernBiotech.

Released: 27-Dec-2018 5:05 PM EST
Engineering Researchers Hit Record with 17 Payloads on the International Space Station
University of Alabama at Birmingham

The December launch of the SpaceX CRS-16 carried the Engineering and Innovative Technology Department’s newly designed Rapid Freezer.

Released: 18-Dec-2018 4:05 PM EST
Uncovering a key mechanism in assembly of Avian Sarcoma Virus, a 100-year-old oncogenic virus often used to study HIV-1
University of Alabama at Birmingham

Researchers used NMR to detail how the matrix domain of the Avian Sarcoma Virus Gag protein binds to certain phospholipids. These phospholipids are vital for Gag protein binding to the plasma membrane of a cell, as the virus replicates and takes its first step toward virus formation and budding.

Released: 14-Dec-2018 12:05 PM EST
$750K grant will help support future Biomedical Engineering predoctoral students
University of Alabama at Birmingham

The UAB Department of Biomedical Engineering is first in the state of Alabama to receive the Ruth L. Kirchstein NRSA Institutional Research Training Grant.

Released: 13-Dec-2018 1:05 PM EST
Saving sacred architecture in Nagpur, India
University of Alabama at Birmingham

West view of the Murlidhar temple at Pardi, built during the Bhosle period, in the late 18th century, Nagpur.An American art history professor could help India preserve some historic religious sculpture and architecture.  Cathleen Cummings, Ph.D., associate professor of art history at the University of Alabama at Birmingham, just returned from a research trip in India.

10-Dec-2018 3:00 PM EST
Five things anyone can do to prevent addiction or help people suffering
University of Alabama at Birmingham

While friends or family members may feel helpless if someone they know suffers from addiction, one UAB physician says hope can start at home.

   
Released: 7-Dec-2018 5:05 PM EST
7 impactful tips to prevent home fires this holiday season
University of Alabama at Birmingham

Enjoy the holiday season while eliminating the possibilities of hazardous home fires.

   
Released: 7-Dec-2018 5:05 PM EST
Does having autism make you more vulnerable to cyber phishing attacks?
University of Alabama at Birmingham

UAB study suggests individuals diagnosed with autism spectrum disorder may not be more prone to cyber phishing attacks compared to those without the disorder.

Released: 5-Dec-2018 12:05 PM EST
Memory B cells in the lung may be important for more effective influenza vaccinations
University of Alabama at Birmingham

Researchers show that lung-resident memory B cells establish themselves in the lung soon after influenza infection in mice. Those lung memory B cells respond more quickly to produce antibodies against influenza after re-infection, and establishment requires a local antigen encounter in the lung.

Released: 30-Nov-2018 3:35 PM EST
A cancer drug may help treat human papillomavirus infections
University of Alabama at Birmingham

Preclinical experiments by University of Alabama at Birmingham researchers suggest the cancer drugs vorinostat, belinostat and panobinostat might be repurposed to treat infections caused by human papillomaviruses, or HPVs.

Released: 29-Nov-2018 2:05 PM EST
“Word from the Mountaintop” Martin Luther King Jr. Oratory Contest seeks local students
University of Alabama at Birmingham

UAB’s Office for Diversity, Equity and Inclusion is accepting submissions for the 2019 second annual “Word from the Mountaintop” MLK Oratory Contest.

Released: 29-Nov-2018 10:05 AM EST
Heads up: UAB does first-ever study of spectator injuries at sporting events
University of Alabama at Birmingham

Sports medicine physicians at UAB present the first study of spectator injuries at major sporting events. Car and motorcycle racing lead the way. The authors call for more safety measures and a central database to record the occurrence of spectator injuries.

Released: 29-Nov-2018 10:05 AM EST
“A 4 percent chance is nothing to me”
University of Alabama at Birmingham

Former MLB player Frank Baker says his experience at UAB’s Pancreatobiliary Disease Center was a home run.

Released: 28-Nov-2018 5:05 PM EST
25th annual toy drive to brighten the lives of children in the Birmingham community
University of Alabama at Birmingham

Holiday partnership between UAB Information Technology and UAB Libraries focuses on community giving and engagement through annual toy drive.

Released: 28-Nov-2018 1:05 PM EST
Wiesen named new chair for Department of History
University of Alabama at Birmingham

Nationally acclaimed history professor Jonathan Wiesen will join UAB in January 2019.

Released: 28-Nov-2018 7:05 AM EST
Experiencing a corneal abrasion in the blink of an eye
University of Alabama at Birmingham

Jessica Martindale’s perfect vision was quickly tested after her infant son inadvertently scratched her cornea. Thankfully, physicians at UAB Callahan Eye Hospital were there to help.

Released: 27-Nov-2018 4:50 PM EST
Cold Weather Woes and Dry Eyes
University of Alabama at Birmingham

It is easy to remember steps to prevent the body from getting cold, but what can be done to protect the eyes when cold weather hits?

Released: 27-Nov-2018 12:05 PM EST
Rapid-freezers for space research launching via SpaceX on Dec. 5
University of Alabama at Birmingham

Upcoming SpaceX launch to include one of three new rapid-freeze devices for future International Space Station missions.

Released: 20-Nov-2018 5:05 PM EST
Ethics Bowl Debate team goes national
University of Alabama at Birmingham

UAB students advance to next level of debates after four-round winning streak at the Southeast Regionals in Jacksonville, Florida.

Released: 19-Nov-2018 2:05 PM EST
Best practices on avoiding credit card identity theft this holiday season
University of Alabama at Birmingham

Security tips on protecting your identity during online and in-store holiday shopping sprees.

Released: 16-Nov-2018 1:05 PM EST
Link discovered between eye calcifications and risk of age-related macular degeneration
University of Alabama at Birmingham

New research show that calcified nodules in the eye increase the risk for progression to advanced AMD.

Released: 13-Nov-2018 11:00 AM EST
An enzyme in immune cells plays essential role in host defense against tuberculosis
University of Alabama at Birmingham

Using freshly resected lung tissue from 21 patients and two distinct mouse models, tuberculosis researchers at the University of Alabama at Birmingham and the Africa Health Research Institute have identified a protein that plays an essential role in host defense against this deadly disease.

Released: 12-Nov-2018 12:05 PM EST
Vaping, e-cigarettes, JUULing: what parents, teens need to know
University of Alabama at Birmingham

For consumers, parents and even teens, understanding terminology and the truth about e-cigarettes can be confusing. UAB physicians debunk common e-cigarette myths with truths.

Released: 9-Nov-2018 12:05 PM EST
Mild blast forces cause pathology and deficits in the brain, despite lack of macroscopic damage
University of Alabama at Birmingham

Mild exposure to a single blast shock wave in a rat model of bTBI is able to induce small but meaningful pathogenic effects that accumulate with time. These effects were detected at the microscopic level. Brain function also changed, as shown by impaired short-term synaptic plasticity.

Released: 9-Nov-2018 10:05 AM EST
Big change from small player — mitochondrial background modulates whole body metabolism and gene expression
University of Alabama at Birmingham

With only 13 genes, human mitochondria are massively overshadowed by the 20,000 genes in the human nucleus. Nevertheless, these diminutive organelles may have a strong influence on cellular metabolism and susceptibility to metabolic diseases like heart failure or obesity.

Released: 8-Nov-2018 4:05 PM EST
Oral Antibiotic Treatment Option for Gonorrhea Identified by UAB Researchers
University of Alabama at Birmingham

Scientists have found that a single-dose of the oral antibiotic zoliflodacin successfully treated uncomplicated genital infections caused by gonorrhea, according to research published in The New England Journal of Medicine.

Released: 7-Nov-2018 3:05 PM EST
Pro-breastfeeding communities empower new moms
University of Alabama at Birmingham

Social media communities supporting moms who are breastfeeding create a unique bond.

Released: 6-Nov-2018 7:00 AM EST
Opinion: Bipartisanship in our genes
University of Alabama at Birmingham

According to the authors, genetic counselors represent a unique resource for the public, patients and other medical professionals and should be more fully incorporated into the health care setting.

Released: 2-Nov-2018 4:05 PM EDT
Molecular virologist fights influenza at the molecular level
University of Alabama at Birmingham

In research to improve influenza therapies against H7N9 and other influenza strains, Chad Petit and colleagues have detailed the binding site and mechanism of inhibition for two small-molecule experimental inhibitors of influenza viruses. Their report is published in the Journal of Biochemistry,



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