Article title: Nrf2 expression in pancreatic stellate cells promotes progression of cancer
Authors: Yu Tanaka, Shin Hamada, Ryotaro Matsumoto, Keiko Taguchi, Masayuki Yamamoto, Atsushi Masamune
From the authors: “These results demonstrate that Nrf2 actively contributes to the function of [pancreatic stellate cells] to sustain KPC cancer progression, thus, suggesting that Nrf2 inhibition in [pancreatic stellate cells] may be therapeutically important in pancreatic cancer.”
This study is highlighted as one of October’s “best of the best” as part of the American Physiological Society's APSselect program.
Journal Link: American Journal of Physiology-Gastrointestinal and Liver Physiology