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Wistar scientists have built upon BTE technology to develop new and improved recombinant and synthetic DNA versions of therapeutic antibodies that target CA9, called Persistent Multivalent T Cell Engager (CA9-PMTE), that shows promise in pre-clinical models as a potent, long-lasting treatment against ccRCC.
In Review of Scientific Instruments, researchers from the University at Buffalo develop a tool for measuring the viscosity of lava that could increase our understanding of molten rock as well as better improve models of its movement, giving authorities crucial guidance for keeping people safe.
According to preliminary data from a multi-institution Phase III trial led by researchers at The University of Texas MD Anderson Cancer Center, intensity modulated proton therapy (IMPT) achieved similar clinical outcomes and offered significant patient benefits when compared to traditional intensity modulated radiation therapy (IMRT) as part of chemoradiation treatment for patients with oropharyngeal (head and neck) cancer.
Thousands of American teens and their families are helping scientists learn more about the growth and development of the brain and its impacts on behavior, mental health and much more, through a national study called ABCD that also includes thousands of other young people nationwide.
Long-necked herbivorous dinosaurs, known as sauropodomorphs, a group of mainly bipedal dinosaurs that lived some 210 million years ago in the Late Triassic, provide a common image of the age of dinosaurs in the minds of people. Now a completely new sauropodomorph species has been identified in Zimbabwe. The discovery is only the fourth dinosaur species discovered in Zimbabwe.
Have you ever wished you could understand what your dog is trying to say to you? University of Michigan researchers are exploring the possibilities of AI, developing tools that can identify whether a dog's bark conveys playfulness or aggression.
In a paper forthcoming in the Journal of Finance, professors at the Indiana University Kelley School of Business, studied firm-level exposures to hurricanes over a 24-year period to better understand how extreme weather events impact performance in financial markets as measured by option and stock prices. They found that investors historically underreacted to the volatility arising from hurricanes and didn’t efficiently update their expectations about it, based on information available in real time.
Circadian clocks, which drive circadian rhythms, are entwined with many essential systems in living things including plants, fungi, insects, and even humans. Because of this, disruptions to our circadian clocks are linked to higher disease rates in humans, including certain cancers and autoimmune diseases. Rensselaer Polytechnic Institute’s Jennifer Hurley, Ph.D., Richard Baruch M.D. Career Development Chair and Associate Department Head of Biological Sciences, has dedicated her career to understanding the mechanisms that allow our circadian clocks to keep time.
Drug-involved infant deaths more than doubled (120% increase) from 2018 to 2022, with the greatest proportion of deaths in 2021 (25.8%). The most prevalent underlying causes of death included assault (homicide) by drugs, medicaments and biological substances (35.6%).
In a triumph for precision agriculture, researchers have pinpointed a tomato exocarp-specific promoter, unlocking the potential for tailored genetic enhancements. This innovation promises to bolster the fruit's visual appeal, fortify it against environmental stressors, and significantly prolong its shelf life.
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