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Heating Up Cold Tumors
Ludwig Cancer Research
A Ludwig Cancer Research study has uncovered a cellular mechanism by which melanomas that fail to respond to checkpoint blockade may be made susceptible to such immunotherapies. Led by Ping-Chih Ho of the Lausanne Branch of the Ludwig Institute for Cancer Research and reported in the current issue of Nature Immunology, the study also identifies an existing diabetes drug that could be used to accomplish that feat.
Energizing the Immune System to Eat Cancer
Perelman School of Medicine at the University of Pennsylvania
Researchers at the Abramson Cancer Center of the University of Pennsylvania say they've identified how to fuel macrophages with the energy needed to attack and eat cancer cells.
No substantial benefit from transplantation reported for a high-risk leukemia subtype
St. Jude Children's Research Hospital
Study led by St. Jude Children's Research Hospital found treatment guided by measuring minimal residual disease was associated with better outcomes for hypodiploid acute lymphoblastic leukemia patients
NCI awards $1.7 million to UIC for research on Southeast Asian fruit
University of Illinois at Chicago
A new $1.7 million grant from the National Cancer Institute will enable researchers at the University of Illinois at Chicago to study the fruit and its potential as a treatment for prostate cancer.
Can Drinking Oolong Tea Help Prevent Breast Cancer?
Saint Louis University Medical Center
SLU scientists and their colleagues have found that oolong tea can damage breast cancer cells and inhibit the growth and progression of tumors in the lab, potentially offering a non-toxic strategy to prevent breast cancer.
UCLA scientists create a renewable source of cancer-fighting T cells
University of California, Los Angeles (UCLA), Health Sciences
A study by UCLA researchers is the first to demonstrate a technique for coaxing pluripotent stem cells -- which can give rise to every cell type in the body and which can be grown indefinitely in the lab -- into becoming mature T cells capable of killing tumor cells.
Low-Intensity Electric Fields Applied to Scalp Can Stop, Slow Growth of Tumor Cells in Newly-Diagnosed Glioblastoma
Henry Ford Health System
Henry Ford Cancer Institute is one of the few cancer programs in Southeast Michigan fighting the most common and deadly brain cancer with tumor-treatment fields, a low-intensity alternating electric field applied with a wearable device that stops or slows the growth of tumor cells in patients with newly diagnosed glioblastoma (GBM).
Child survivors of Hodgkin lymphoma have increased risk of second cancer
University of Alabama at Birmingham
Survivors of childhood Hodgkin lymphoma are at an increased risk of developing an entirely new cancer later in life, according to new research published in Cancer -- the American Cancer Society's international peer-reviewed scientific journal -- and conducted at University of Alabama at Birmingham.
Whole Genome Sequencing Method May Speed Personalized Treatment Of Drug-Resistant Infections
Johns Hopkins Medicine
Researchers at Johns Hopkins Medicine say they have added to evidence that rapid resistance gene sequencing technology can accurately speed the identification of specific antibiotic-resistant bacteria strains that sicken and kill some patients. A report on a proof of concept study, published in the January 2019 issue of Antimicrobial Agents and Chemotherapy, suggests the technology has the potential to hasten the "personalized" choice of antibiotics critically ill patients need.
Jean-Pierre Issa, MD, Expert in Cancer Epigenetics, to Lead Coriell Institute for Medical Research as President and CEO
Coriell Institute for Medical Research
Jean-Pierre Issa, MD, a world-renowned expert in the epigenetics of cancer and director of Temple University's Fels Institute for Cancer Research and Molecular Biology, will join the Coriell Institute for Medical Research as its new President and Chief Executive Officer, Coriell's Board of Trustees Chairman Robert Kiep, III, announced today.
Rutgers Scientist Identifies Gene Responsible for Spread of Prostate Cancer
Rutgers University-New Brunswick
A recent study has found that a specific gene in cancerous prostate tumors indicates when patients are at high-risk for the cancer to spread, suggesting that targeting this gene can help patients live longer.
Breast cancer up to 5 times more likely to metastasize even 10 years after childbirth
University of Colorado Cancer Center
University of Colorado Cancer Center study shows that doctors may be underestimating the risk of and thus under-treating stage I and II breast cancers diagnosed within 10 years of childbirth.
Novel Imaging Technology May Help Reduce Biopsies for Breast Tumors
Washington University in St. Louis
Scientists at Washington University in St. Louis plan to use a new imaging technique to get a better look at breast tumors and reduce unnecessary biopsies.
Acupressure relieves long-term symptoms of breast cancer treatment, study finds
Michigan Medicine - University of Michigan
A new study finds acupressure could be a low-cost, at-home solution to a suite of persistent side effects that linger after breast cancer treatment ends.
Scientists have identified a bone marrow backup system
Stowers Institute for Medical Research
New research from the Stowers Institute for Medical Research has identified a backup for an important biological system - the hematopoietic system, whose adult stem cells constantly replenish the body's blood supply.
Roswell Park Comprehensive Cancer Center Named One of America's Best Employers for Diversity
Roswell Park Comprehensive Cancer Center
Roswell Park Comprehensive Cancer Center has been recognized as one of America's Best Employers for Diversity 2019. The Buffalo cancer center was ranked 67th among 500 employers and 8th among the 30 employers within the health care sector to be named to the list, which is based on employee surveys.
Fellowship Program at Rutgers Aims to Improve Access to Surgical Care in Colombia--and Closer to Home
Rutgers Robert Wood Johnson Medical School
Global surgery is often referred to as the neglected stepchild of global health, but Gregory Peck, DO, assistant professor of surgery at Rutgers Robert Wood Johnson Medical School, is trying to change that through a global surgery fellowship program that unites surgeons and non-surgeons in health systems based research and development.
Gene-Editing Tool CRISPR/Cas9 Shown to Limit Impact of Certain Parasitic Diseases
George Washington University
For the first time, researchers at the GW School of Medicine and Health Sciences have successfully used the gene-editing tool CRISPR/Cas9 to limit the impact of parasitic worms responsible for schistosomiasis and for liver fluke infection, which can cause a diverse spectrum of human disease including bile duct cancer.
States with Fewer Melanoma Diagnoses Have Higher Death Rates
University of Utah Health
Researchers at University of Utah Health conducted a state-by-state analysis to understand the geographic disparities for patients diagnosed with melanoma. The results of their study suggest that lower survival is associated with more practicing physicians in a region and higher population of Caucasians.
Penn's Abramson Cancer Center Welcomes New Director's Leadership Council Chair
Perelman School of Medicine at the University of Pennsylvania
The Abramson Cancer Center at the University of Pennsylvania announced today that Richard S. Schiffrin, Esq., has been appointed chair of the Center Director's Leadership Council.
Muscle Stem Cells Can Drive Cancer That Arises in Duchenne Muscular Dystrophy
Sanford Burnham Prebys Medical Discovery Institute
Scientists from Sanford Burnham Prebys Medical Discovery Institute (SBP) have demonstrated that muscle stem cells may give rise to rhabdomyosarcoma that occurs during DMD--and identified two genes linked to the tumor's growth. The research, performed using a mouse model of severe DMD, helps scientists better understand how rhabdomyosarcoma develops in DMD--and indicates that ongoing efforts to develop treatments that stimulate muscle stem cells should consider potential cancer risk. The study was published today in Cell Reports.
NCCN Guidelines Raise Standards for Cancer Care Worldwide by Exceeding 10 Million Downloads in 2018 -- Up 26% Over 2017
National Comprehensive Cancer Network(r) (NCCN(r))
The National Comprehensive Cancer Network(r) (NCCN(r)) announced that the NCCN Clinical Practice Guidelines in Oncology (NCCN Guidelines(r)) were downloaded more than 10 million times in 2018; marking a 26% increase over 2017.
A Family Faces a Cancer Crisis Together
UT Southwestern Medical Center
Catherine Carr Worley was 41 years old with a 2-month-old when she was diagnosed with inflammatory breast cancer.
Complication rates and costs of invasive lung cancer diagnostic tests may be higher than anticipated
University of Texas M. D. Anderson Cancer Center
Complication rates following invasive diagnostic procedures for lung abnormalities were twice as high in community settings compared to those reporter in lung screening trials, according to an MD Anderson study.
More accurate leukemia diagnosis expected as researchers refine leukemia classification
St. Jude Children's Research Hospital
More than 90 percent of B-ALL cases can now be classified by subtype, up from 70 percent several years ago. The number of proposed B-ALL subtypes is now 23.
In breast-cancer prevention, race matters
Ohio State University
African-American women at high risk of breast cancer are less likely than white women to pursue potentially life-saving preventive care, and racial disparities in health care and elsewhere are to blame, new research suggests.
ASTRO applauds selection of Dr. Anand Shah for senior medical innovation role within CMS
American Society for Radiation Oncology (ASTRO)
The Chair of the American Society of Radiation Oncology (ASTRO) Board of Directors, Paul Harari, MD, FASTRO, issued the following statement today in support of Centers for Medicare and Medicaid Services (CMS) Administrator Seema Verma's announcement that Dr. Anand Shah was named Senior Medical Advisor for Innovation at CMS.
Novel Biomarker Appears Predictive of Outcome in Patients with HPV-Related Head and Neck Cancers
University of Texas M. D. Anderson Cancer Center
Rather than classifying based solely on HPV status, MD Anderson researchers have discovered a new biomarker for head and neck cancers that may enable clinicians to better predict patient outcomes and lower treatment intensity to reduce side effects.
A Long Shot Could Bear Fruit
New Mexico State University (NMSU)
A compound discovered by Jeffrey Arterburn of New Mexico State University and Eric Prossnitz of University of New Mexico is currently in pre-clinical trials. if they go well, human trials will begin at a few sites around the country, led by the UNM Comprehensive Cancer Center.
The Medical Minute: Screenings, Vaccine Prevent Cervical Cancer
Penn State Health
January is Cervical Health Awareness Month, and the National Cervical Cancer Coalition is urging women to make a New Year's resolution to talk with their health care providers.
UCLA study overturns dogma of cancer metabolism theory - tumors not as addicted to glucose as previously thought
UCLA Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research
Scientists at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA have discovered that squamous cell skin cancers do not require increased glucose to power their development and growth, contrary to a long-held belief about cancer metabolism. The findings could bring about a better understanding of many cancers' metabolic needs and lead to the development of more effective therapies for squamous cell skin cancer and other forms of epithelial cancer.
Metabolite produced by gut microbiota from pomegranates reduces inflammatory bowel disease
University of Louisville
LOUISVILLE, Ky. - Scientists at the University of Louisville have shown that a microbial metabolite, Urolithin A, derived from a compound found in berries and pomegranates, can reduce and protect against inflammatory bowel disease (IBD). Millions of people worldwide suffer from IBD in the form of either ulcerative colitis or Crohn's disease, and few effective long-term treatments are available.
First-in-Class DNA-encoded Monoclonal Antibody Therapy Rapidly Advances into the Clinic
Wistar Institute
Wistar, along with partners Penn Medicine and Inovio Pharmaceuticals, Inc. announce the FDA has approved the initiation of a first-in-human clinical trial investigating safety and tolerability of a novel synthetic DNA-encoded monoclonal antibody (DMAb) therapeutic technology for the prevention of Zika virus infection.
Mercy Colorectal Surgeon Dr. Jeffery Nelson Performs Minimally Invasive Outpatient Treatment for Hemorrhoids
Mercy Medical Center, Baltimore
Jeffery Nelson, M.D., FACS, FASCRS, Surgical Director of The Center for Inflammatory Bowel and Colorectal Diseases, Institute for Digestive Health & Liver Disease at Mercy Medical Center in Baltimore, MD, now offers patients a minimally invasive, outpatient procedure for treating hemorrhoids.
# 1 in NIH Funding for Second Consecutive Year
University of Pennsylvania School of Nursing
With $13.4 million dollars in awards from the National Institutes of Health (NIH), the University of Pennsylvania School of Nursing (Penn Nursing) retains its top spot for research funding for the 2018 fiscal year, among other schools of nursing. This is the second consecutive year Penn Nursing has earned first place.
Hackensack University Medical Center Holds Third Annual Graduation Ceremony for Nurses in Blood and Marrow Transplant Fellowship Program
Hackensack Meridian Health
Hackensack Meridian Health Hackensack University Medical Center recently held the third annual Blood and Marrow Transplant (BMT) RN Fellowship Graduation Ceremony for nine registered nurses. The nurses are from 8PE and 8PW Blood and Marrow Transplant (BMT) units.
John Mendelsohn, MD Anderson President Emeritus, Passes Away
University of Texas M. D. Anderson Cancer Center
John Mendelsohn, M.D., president emeritus of The University of Texas MD Anderson Cancer Center and an internationally acclaimed leader in the field of medicine and scientist whose research helped pioneer a new type of cancer therapy, died Jan. 7 at his home in Houston. He was 82. The cause of death was glioblastoma, an aggressive form of brain cancer with which he was diagnosed 15 months ago.
Henry Ford Cancer Institute Enrolls First Patient in Pancreatic Cancer Research Study
Henry Ford Health System
The Henry Ford Cancer Institute announced today it has enrolled the first patient in a new clinical trial to test the effectiveness of using precise, higher dose MRI-guided radiation therapy to treat pancreatic cancer.
Northwestern Urology Program Receives $10M Gift from the Polsky Family to Create a Urologic Cancer Institute
Northwestern Medicine
Northwestern Medicine received a $10 million gift to fund the creation of a new multidisciplinary institute dedicated to urologic cancers.
Genetic testing does not cause undue worry for breast cancer patients
Michigan Medicine - University of Michigan
As genetic testing for breast cancer has become more complex, evaluating a panel of multiple genes, it introduces more uncertainty about the results. But a new study finds that newer, more extensive tests are not causing patients to worry more about their cancer risk.
MD Anderson notes passing of Waun Ki Hong - innovator, mentor, colleague
University of Texas M. D. Anderson Cancer Center
Waun Ki Hong, M.D., a trail-blazing physician-scientist and mentor whose clinical research innovations led to successful organ-sparing cancer treatment, advanced the field of targeted therapy and launched chemoprevention, died Wednesday at his home in California. Hong, 76, retired from The University of Texas MD Anderson Cancer Center as head of the Division of Cancer Medicine in 2014. He remained as a special advisor to a variety of MD Anderson programs that nurtured the careers of young scientists.
Landmark Mammography Study Highlights the Importance of Breast Cancer Screening
UCSF Helen Diller Family Comprehensive Cancer Center
A landmark mammography study has found that women who receive annual breast cancer screenings will have a lower mortality rate and will benefit more from therapy upon diagnosis of breast cancer.
Study Shows New Way to Group Protein Kinases as Cancer Drug Targets
Stony Brook University
A new study published early online in Cell Chemical Biology led by Markus Seeliger, PhD, Associate Professor of Pharmacological Sciences in the Renaissance School of Medicine at Stony Brook University, takes a fresh approach to grouping kinases as potential drug targets.
An Errant Editing Enzyme Promotes Tumor Suppressor Loss and Leukemia Propagation
University of California San Diego Health
UC San Diego researchers have found a stem cell enzyme copy edits more than 20 tumor types, providing new therapeutic target for preventing cancer cell resistance to chemotherapy and radiation.
Solid Tumor Genomic Sequencing can Reveal Coexistent Hematologic Malignancy
Rutgers Cancer Institute of New Jersey
Investigators at Rutgers Cancer Institute have uncovered that some mutations detected with targeted genome sequencing of patients with solid tumors are a result of a group of hematologic malignancies known as myeloproliferative neoplasms (MPN). This discovery may have direct implications for treating cancer patients who may have a solid tumor as well as a MPN.
Improved Overall Survival Shown in Pediatric Hodgkin Lymphoma Patients when Receiving Combined Modality Treatment
Rutgers Cancer Institute of New Jersey
Research from Rutgers Cancer Institute of New Jersey shows improved overall survival at five years for pediatric patients with early-stage Hodgkin lymphoma when treated with chemotherapy followed by radiotherapy versus chemotherapy alone.
Single-Incision Surgery Speeds Recovery for Cancer Patient
UT Southwestern Medical Center
A new robotic surgery device allows for all of the necessary surgical tools to be inserted through one 1-inch hole, whereas standard laparoscopic surgery requires five or six small incisions.
Mount Sinai and Man Cave Health Launch Sports-Themed Resource Center
Mount Sinai Health System
The Department of Urology at the Mount Sinai Health System has partnered with the nonprofit organization Man Cave Health to launch a first-of-its-kind sports-themed resource center for men that will provide educational resources on prostate health.
CMS Approves GIQuIC as a Qualified Clinical Data Registry for the 2019 Reporting Year
American College of Gastroenterology (ACG)
The GI Quality Improvement Consortium, Ltd. (GIQuIC) Registry has been approved as a Qualified Clinical Data Registry (QCDR) for reporting to the Merit-based Incentive Payment System (MIPS) for the 2019 reporting year. GIQuIC will host an informational webinar on reporting via the GIQuIC 2019 QCDR in February 2019.
Soper Inducted into AIMBE College of Fellows
University of Kansas Cancer Center
Steven Soper, PhD, member of The University of Kansas Cancer Center, was elected to the American Institute for Medical and Biomedical Engineering (AIMBE) College of Fellows.
HSS Receives Half Million Dollar Grant to Investigate How to Improve Health Care System for Chronically Ill Adolescents
Hospital for Special Surgery
The "I'm Not Done Yet" Foundation" on Long Island has pledged a $500,000 research grant to Hospital for Special Surgery in New York City to establish best practices to meet the changing needs of young patients as they become teenagers and young adults in the health care system.
A Resolution for Good Health
Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute experts share more about the importance of preventative screenings for colorectal and lung cancers.
2018: Cedars-Sinai Cancer Investigators Pioneer Novel Research, Targeted Therapies
Cedars-Sinai
Cedars-Sinai Cancer drove major advances in cancer research in 2018. Among these was a study about a pancreatic cancer drug, Metavert, developed by Cedars-Sinai investigators to prevent the most common type of pancreatic cancer from growing and spreading. Other groundbreaking research this year focused on reducing health disparities, the latest treatment options for newly diagnosed melanoma patients, and a study outlining a new, more accurate system for assessing the severity of head and neck cancers and for predicting patient survival.
2018: Advances in Neurology
Cedars-Sinai
Physician-researchers at Cedars-Sinai are available to discuss neuroscience findings from 2018. Several are detailed in this news release, including a study that found prolonged exposure to particulate matter in air pollution can cause changes in the brain. These changes could make people more susceptible to cancer, Alzheimer's disease and other neurological disorders.
New research explores policies on timely breast cancer diagnosis for underserved women
University of Illinois at Chicago
Delays in diagnosis and use of under-resourced health centers account for most racial and ethnic disparities when it comes to a timely breast cancer diagnosis, according to a new study.
Georgetown Genetic Counselor Offers Insight On Direct-to-Consumer DNA Testing Kits
Georgetown University Medical Center
Direct-to-consumer DNA testing kits are expected to be a popular holiday gift this year, with 100 million people expected to have used one by 2020--but an expert genetic counselor at Georgetown says consumers should understand a few pros and cons before using one.
Yale Cancer Center scientists advise caution in immunotherapy research
Yale Cancer Center
In a new study by Yale Cancer Center (YCC), scientists suggest that as the number of clinical trials in cancer immunotherapy grows exponentially, some caution should be exercised as we continue to better understand the biology of these new therapeutic targets.
Genome offers clues to esophageal cancer disparity
Michigan Medicine - University of Michigan
A change in the genome of Caucasians could explain much-higher rates of the most common type of esophageal cancer in this population, a new study finds. It suggests a possible target for prevention strategies, which preliminary work suggests could involve flavonoids derived from cranberries.
Nuclear Medicine? It's Probably Not at All What You Think It Is
Wake Forest Baptist Medical Center
The often-misunderstood specialty employs low doses of radioactive materials and advanced imaging technologies to diagnose and treat a variety of diseases.
How Children & Teens Die in America: Study Reveals the Widespread & Persistent Role of Firearms
Michigan Medicine - University of Michigan
America lost 20,360 children and teens in 2016 -- 60 percent of them to preventable injuries, a new study shows. But while death rates from the top cause - motor vehicle crashes - have declined steadily since 1999, rates from the second-leading cause - firearms - have gone up. It's the first time all causes of child and adolescent death have been tallied by both mechanism and intent.
Neoantigen vaccine spurs immune response in glioblastoma
Dana-Farber Cancer Institute
In a report published in Nature, however, scientists at Dana-Farber Cancer Institute say they have shown that a personalized 'neoantigen' vaccine can spur a response against glioblastoma, with immune T-cells generated by the vaccine migrating into the brain tumor, creating a 'hotter,' inflamed environment around the cancer cells.
Researchers Suggest Current Methods for Reporting Toxicities in Cancer Clinical Trials are Falling Short
National Comprehensive Cancer Network(r) (NCCN(r))
Findings published in JNCCN-Journal of the National Comprehensive Cancer Network examine the differences between patient- and clinician-reported outcomes; recommend a greater focus on the cumulative effect of multiple low-level toxicities.
DNA "Webs" Aid Ovarian Cancer Metastasis, Study Reveals
The Rockefeller University Press
Researchers from the University of Texas MD Anderson Cancer Center have discovered that ovarian cancer cells spread, or metastasize, to new tissue after being caught in DNA "webs" extruded by immune cells. The study, which will be published December 19 in the Journal of Experimental Medicine, reveals that preventing immune cells from forming these webs reduces metastasis in mice, suggesting that similar treatments could be used to limit the spread of ovarian cancer in humans.
Two Ways Cancer Resists Treatment Are Actually Connected, with One Activating the Other
Perelman School of Medicine at the University of Pennsylvania
Researcher shows the two most common means of resistance to BRAF and MEK inhibitors are actually connected processes and can be targeted by other therapies.
Prostate cancer scoring method may underestimate mortality risk in black men
Dana-Farber Cancer Institute
Black men diagnosed with prostate cancer classified as low risk may actually have a more aggressive form of the disease that is more likely to be fatal than in nonblack men placed in the same prognostic category, a new study suggests.
Vaccine, Checkpoint Drugs Combination Shows Promise for Pancreatic Cancers
Johns Hopkins Medicine
Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.
Cancer Caregivers: How to Manage 'Happy' During the Holidays
Cedars-Sinai
Families and caregivers of people with cancer may view the holidays as a particularly challenging time, often feeling as though they have to live up to the ideal of merry and bright, when they--and those they're tending--typically don't feel that way. Cedars-Sinai experts offer 6 tips for making the most of the holidays while caring for someone with cancer.
An Online Intervention to Reduce Skin Cancer in Young Adults
Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey is leading a research study aimed at improving skin cancer protection behaviors in young adults through an online intervention.
BIDMC's Research & Health News Digest: December 2018 Edition
Beth Israel Deaconess Medical Center
A monthly roundup of research briefs showcasing recent scientific advances led by Beth Israel Deaconess Medical Center faculty.
Cancer Researcher Identifying Ways to Overcome Drug-Resistance
South Dakota State University
Assistant Professor Iram Surtaj will use a new imaging technique to identify drugs that can disrupt overexpression of multidrug resistance protein 1, one of the main mechanisms through which cancer cells gain resistance to chemotherapy drugs.
E-Cigarette Users Have Lower Exposure to Toxicants -- As Long As They Don't Smoke Combustible Cigarettes Too
Roswell Park Comprehensive Cancer Center
The largest study to date to compare exposure to toxicants among users of electronic cigarettes, smokers and nonsmokers has been completed, suggesting possible benefits for smokers who switch completely to electronic cigarettes
Study identifies location of DNA that gives clues to hidden cancer mutations
University of California, Los Angeles (UCLA), Health Sciences
A new study by UCLA scientists shows that enhancers, snippets of DNA that contribute to gene regulation, fall into the same "insulated neighborhoods" or chromatin loops as the target gene and other gene-specific regulatory elements.
NIH scientists find that breast cancer protection from pregnancy starts decades later
National Institute of Environmental Health Sciences (NIEHS)
In general, women who have had children have a lower risk of breast cancer compared to women who have never given birth. However, new research has found that moms don't experience this breast cancer protection until many years later and may face elevated risk for more than 20 years.
Children's Hospital of Philadelphia Announces Endowed Chair in Pediatric Neuroblastoma Research
Children's Hospital of Philadelphia
Pediatric oncologist and researcher Yael Mosse, MD, Director of the Neuroblastoma Development Therapeutics Program at Children's Hospital of Philadelphia, has been named the inaugural holder of the Patricia Brophy Endowed Chair in Neuroblastoma Research.
Exercise Significantly Cuts the Risk of Death from Cancer
Roswell Park Comprehensive Cancer Center
New research out of Roswell Park Comprehensive Cancer Center shows that cancer patients who exercise regularly both before and after their diagnosis are significantly more likely to survive than those who are sedentary, adding to the growing body of evidence that physical activity is an important part of a cancer prevention and treatment strategy. The results were published in a recent issue of the journal Cancer Causes & Control.
The "Greying" of T Cells
Harvard Medical School
Research in mouse cells identifies defective metabolic pathway in aging immune T cells. The pathway is critical for switching T cells from dormancy into illness-fighting mode. In experiments, researchers restored lagging T-cell function by adding small-molecule compounds. Findings suggest possible mechanism behind weakened immunity common in the elderly.
The Nicola-Musso Charitable Foundation and Carol Musso Foley Commit to a Generous Donation for Cancer Care at Two Hackensack Meridian Health Hospitals
Hackensack Meridian Health
Hackensack Meridian Health and the Meridian Health Foundation are pleased to announce a gift of $750,000 from the Nicola-Musso Charitable Foundation of New York, N.Y. and Carol Musso Foley of New York and Spring Lake, NJ, to be used to enhance cancer care services at Hackensack Meridian Health Jersey Shore University Medical Center and Hackensack Meridian Health Ocean Medical Center.
New Technology for Profiling Myeloma Cells
Weizmann Institute of Science
Weizmann Institute scientists Profs. Ido Amit and Amos Tanay, working with hemato-oncologists, have created a new way to profile myeloma tumor cells. The machine-learning-based technique will allow earlier and better diagnosis of the cancer, including in terms of relapse, and improve treatment.
Pushing Closer to a New Cancer-Fighting Strategy
Johns Hopkins Medicine
A molecular pathway that's frequently mutated in many different forms of cancer becomes active when cells push parts of their membranes outward into bulging protrusions, Johns Hopkins researchers report in a new study. The finding, published Nov. 7 in Nature Communications, could eventually lead to new targets for cancer-fighting therapeutics.
Study finds higher risk of breast cancer for women after giving birth
University of North Carolina Health Care System
A collaborative group of researchers co-led by a UNC Lineberger Comprehensive Cancer Center scientist found that, in women 55 years and younger, breast cancer risk peaked about five years after they gave birth, with risk for mothers 80 percent higher compared with women who did not give birth.
Sprayable gel developed by UCLA-led team could help the body fight off cancer after surgery
University of California, Los Angeles (UCLA), Health Sciences
Many people who are diagnosed with cancer will undergo some type of surgery to treat their disease -- almost 95 percent of people with early-diagnosed breast cancer will require surgery and it's often the first line of treatment for people with brain tumors, for example. But despite improvements in surgical techniques over the past decade, the cancer often comes back after the procedure.
Workshop Promotes Patient Advocacy in Cancer Research
University of Kansas Cancer Center
The University of Kansas Cancer Center and the the Midwest Cancer Alliance co-hosted an introductory training workshop for individuals who want to learn more about KU Cancer Center's patient research advocacy program, PIVOT
Penny DeGoosh named director of Social Work at St. Jude Children's Research Hospital
St. Jude Children's Research Hospital
Penny DeGoosh, LICSW, has been named the director of Social Work at St. Jude Children's Research Hospital.
MD Anderson study shows key enzyme linked to therapy resistance in deadly lung cancer
University of Texas M. D. Anderson Cancer Center
Researchers at The University of Texas MD Anderson Cancer Center have identified a link between an enzyme tied to cancer formation and therapy resistance in patients with epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC).
Media Advisory: Young Age Associated with Worse Prognosis in Specific Breast Cancer Subtype
Johns Hopkins Medicine
Researchers at Johns Hopkins Kimmel Cancer Center are rapidly advancing the understanding of biological factors, including hormones, as predictors of longer disease-free survival for certain subtypes of breast cancer. The implications for treatment -- especially among younger women -- can be profound, but uncertainties remain and decision-making by patients and their physicians can be complicated.
Living With Cancer: Some Men With Prostate Cancer Opt Out of Surgery
Cedars-Sinai
Of the 165,000 men in the U.S. expected to be diagnosed with prostate cancer this year, about half will have low-risk disease. Many of those patients will opt for active surveillance -- a process in which men with low-risk, slow-growing prostate cancer are regularly monitored to see if the cancer starts to grow and requires treatment.
Using inkjet printers to build a new biosensor for less invasive breast cancer detection
National Institute of Biomedical Imaging and Bioengineering
NIBIB-funded researchers have created a novel, low-cost biosensor to detect HER-2, a breast cancer biomarker in the blood, allowing for a far less invasive diagnostic test than the current practice, a needle biopsy. Scientists at the Universities of Hartford and Connecticut and funded in part by NIBIB, combined microfluidic technology with diagnostics, including electrochemical sensors and biomarkers, into a powerful package that can give results in about 15 minutes.
UC San Diego Researcher Gets $4 Million NCI Award to Study Cancer Drug Resistance, Spread
University of California San Diego Health
David Cheresh, Distinguished Professor at University of California San Diego School of Medicine, received $4.2 million National Cancer Institute Outstanding Investigator Award to continue his research into cancer's ability to overcome stress, gain drug resistance and metastasize.
Some people uncomfortable discontinuing colorectal cancer screening even when benefit is low
Michigan Medicine - University of Michigan
A new study finds 29 percent of veterans who underwent recommended screening colonoscopies were uncomfortable with the idea of stopping these screenings when the benefit was expected to be low for them personally.
NYU Langone Hospital-Brooklyn Welcomes Cancer Surgeon and Skilled Researcher
NYU Langone Hospital - Brooklyn
Camilo Correa, MD, is a surgical oncologist specializing in liver, pancreas, bile duct, and intestinal cancers. A native of Colombia, Correa completed a postdoctoral research fellowship at Harvard Medical School and a clinical fellowship at Memorial Sloan Kettering Cancer Center.
New Molecular Tool Identifies Sugar-Protein Attachments
Johns Hopkins Medicine
Researchers at Johns Hopkins Medicine have developed a new molecular tool they call EXoO, which decodes where on proteins specific sugars are attached--a possible modification due to disease. The study, published in issue 14 of Molecular Systems Biology, describes the development of the tool and its successful use on human blood, tumors and immune cells.
Multidisciplinary care improves outcomes of patients with brain metastases
UT Southwestern Medical Center
New data reveals the life expectancy of patients with kidney cancer that's traveled to the brain has now stretched from months to years.
Southern Research Introduces Transgenic Mouse Model in Support of Immuno-Oncology Therapeutic Development
Southern Research
Southern Research has announced the Transgenic Mouse Human PD-1/L1 Model, its newest service offering in support of immuno-oncology (IO) therapeutic development.
Scientists Design Way to Track Steps of Cells' Development
Washington University in St. Louis
Scientists at Washington University School of Medicine in St. Louis have developed a new tool described as a "flight data recorder" for developing cells, illuminating the paths cells take as they progress from one type to another. This cellular tracking device could one day help scientists guide cells along the right paths to regenerate certain tissues or organs, or help study the origins of cancer.
UC San Diego Researchers Develop Sensors to Detect and Measure Cancer's Ability to Spread
University of California San Diego Health
University of California San Diego School of Medicine researchers engineered sensors to detect and measure the metastatic potential of single cancer cells. Metastasis is attributed as the leading cause of death in people with cancer.
What Can Hair Tell About? A Non-Invasive Diagnostics of Diseases Is Discovered at SUSU
South Ural State University
It is an often case that one's health and life depend on as quick a disease is found. That is why today the ways of quick and effective revealing of a disease is one of the most important directions in medicine.
SUSU Scientists Study Light to Create Technologies of the Future
South Ural State University
Scientists of the Faculty of Physics of the SUSU Institute of Natural Sciences and Mathematics predict new optical effects in light beams which in perspective will help create technologies of the future, and even reveal cancer in early stages.
UC San Diego Medical Center Named by Leapfrog as "2018 Top Teaching Hospital"
University of California San Diego Health
UC San Diego Medical Center in Hillcrest was named a Top Teaching Hospital by The Leapfrog Group. The award is widely acknowledged as one of the most competitive honors that a U.S. hospital can receive.
Penn's Basser Center for BRCA Chooses Memorial Sloan Kettering, Cornell University Researcher Maria Jasin for 2018 Basser Global Prize
Perelman School of Medicine at the University of Pennsylvania
The Basser Center for BRCA at Penn Medicine's Abramson Cancer Center, the world's first comprehensive center aimed at advancing research, treatment, and prevention of BRCA-related cancers, has announced Maria Jasin, PhD, as the recipient of the sixth annual Basser Global Prize. Jasin is a member of the Developmental Biology Program at Memorial Sloan Kettering Cancer Center and a professor at the Weill Graduate School of Medical Sciences at Cornell University.
New Cancer Immunotherapy Approach Turns Immune Cells into Tiny Anti-Tumor Drug Factories
University of California San Diego Health
In lab and mouse experiments, UC San Diego School of Medicine researchers developed a method to leverage B cells to manufacture and secrete tumor-suppressing microRNAs.