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Why eating yogurt may help lessen the risk of breast cancer
Lancaster University
One of the causes of breast cancer may be inflammation triggered by harmful bacteria say researchers.
Researchers uncover two-drug combo that halts the growth of cancer cells
UT Southwestern Medical Center
UT Southwestern Simmons Cancer Center researchers have discovered a two-drug combo that halts the growth of cancer cells that carry HER2 mutations.
New Drug Target for Prostate Cancer Found in the Non-Coding Genome
University Health Network (UHN)
Scientists at Princess Margaret Cancer Centre have identified the drivers of a crucial gene involved in prostate cancer, revealing new targets for drug design.
Medical Minute: Trying to quit smoking? Don't go it alone.
Penn State Health
We live in an era of self-empowerment. But when it comes to quitting smoking, going it alone isn't the best approach. Read on for effective strategies from Penn State Health experts.
Daron G. Ferris, MD, to Receive 2020 Penn Nursing Renfield Foundation Award for Global Women's Health
University of Pennsylvania School of Nursing
Daron G. Ferris, MD, the Founder of CerviCusco, will receive the 2020 Penn Nursing Renfield Foundation Award for Global Women's Health for his dedication to cervical cancer prevention among the indigenous women in Cusco, Peru. Ferris created CerviCusco, a non-profit organization that ensures all women, including those with limited economic resources, have access to high quality and affordable health education and care, including screening, diagnosis, and treatment of cervical cancer. Ferris will receive the award - which comes with a $100,000 cash prize - during an event at the University of Pennsylvania on April 23, 2020.
International Research Team Confirms Potential Glioblastoma Inhibitors
University of California San Diego
However, San Diego Supercomputer Center (SDSC) Research Scientist Igor Tsigelny recently collaborated Researchers from the San Diego Supercomputer at UC San Diego and colleagues from Sweden's Karolinska Institute and the Pasteur Institute in France released a study focused on improving the prognosis for glioblastoma patients.
Meridian Health Foundation's Giving Heals Campaign Bolstered by Team Member Support
Hackensack Meridian Health
Team members from eight Hackensack Meridian Health medical centers raised nearly $330,000 for Giving Heals, Meridian Health Foundation's comprehensive fundraising campaign, which supports four important initiatives: strengthening oncology services, improving clinical outcomes, enhancing the patient experience and broadening clinical research and academic programs. To date, nearly $110 million has been raised toward a goal of $150 million to support Hackensack Meridian Health medical centers in Monmouth, Ocean and Middlesex counties.
While Promoting Diseases Like Cancer, These Enzymes Also Cannibalize Each Other
Georgia Institute of Technology
In diseases like cancer, atherosclerosis, and sickle cell anemia, cathepsins promote their propagation. Drug trials to inhibit these enzymes have failed due to baffling side effects. Now a new study examines cathepsins in systems to remove some of the bafflement.
Dozens of potential anti-cancer drugs netted in massive screening study
Dana-Farber Cancer Institute
A variety of existing drugs for treating conditions such as diabetes, inflammation, alcohol abuse, and arthritis in dogs can also kill cancer cells in the lab, according to a study by scientists at Dana-Farber Cancer Institute and the Broad Institute of MIT and Harvard.
Select few cancer patients enroll in potentially life-extending clinical trials
Penn State College of Medicine
Patient enrollment in clinical trials as the first course of treatment after cancer diagnosis is low, despite the fact that enrollment may increase life expectancy, according to researchers at Penn State.
Why aren't advanced bladder cancers being treated?
UC Davis Comprehensive Cancer Center
Despite research showing that aggressive treatment with surgery, chemotherapy and radiation can extend the lives of and even cure patients with advanced bladder cancer, many don't get it. The result, argues a team led by UC Davis Health urologists, is that the disease for many is still as deadly as it was 30 years ago.
Virtual Reality and Breast Cancer, First Italian-American Study Shows Promising Results
Sbarro Health Research Organization (SHRO)
Virtual Reality during chemotherapy shown to improve breast cancer patients' quality of life during the most stressful treatments, according to a recent study.
Hackensack Meridian Health Center for Discovery and Innovation to Host Genomic Medicine Symposium
Hackensack Meridian Health
The Symposium on February 19 will feature a variety of clinical disorders in which prevention, screening, and treatment can be informed through genomic and epigenomic data.
UTSW Researchers Uncover New Vulnerability in Kidney Cancer
UT Southwestern Medical Center
Qing Zhang, Ph.D., and his colleagues identified a possible way to treat tumors while sparing nearby healthy tissue.
Cancer study may accidentally help researchers create usable blood stem cells
University of Colorado Cancer Center
University of Colorado Cancer Center study shows healthy form of the leukemia-causing gene MLL may push pluripotent stem cells (which have proven difficult to use in human patients) to become durable hematopoietic stem cells (which are usable in patients, but have until now been impossible to make).
John Theurer Cancer Center Participating in Early-Phase Study of Immunotherapy-Boosting Treatment
Hackensack Meridian Health
Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey are participating in a first-in-patients clinical trial assessing VE800, a novel bacteria-containing therapy, in combination with the immunotherapy drug nivolumab. Laboratory research has suggested that VE800 may enhance the effectiveness of drugs like nivolumab.
Partnership with China Prompts Change in Care for High-Risk Type of Leukemia
St. Jude Children's Research Hospital
Researchers from St. Jude Children's Research Hospital and the Chinese Children's Cancer Group led the first randomized, Phase III clinical trial comparing targeted therapies for acute lymphoblastic leukemia (ALL) driven by the Philadelphia chromosome. Results showed that the drug dasatinib provides more benefit than the standard of care, which led to changes in the way this leukemia is treated. The findings were reported today in JAMA Oncology.
Zika Virus' Key into Brain Cells ID'd, Leveraged to Block Infection and Kill Cancer Cells
University of California San Diego Health
Two different UC San Diego research teams identified the same molecule -- αvβ5 integrin -- as Zika virus' key to brain cell entry. They found ways to take advantage of the integrin to both block Zika virus from infecting cells and turn it into something good: a way to shrink brain cancer stem cells.
Special delivery: McMaster physicists design 'super-human' red blood cells to deliver drugs to specific targets within the body
McMaster University
A team of physicists from McMaster University has developed a process to modify red blood cells so they can be used to distribute drugs throughout the body, which could specifically target infections or treat catastrophic diseases such as cancer or Alzheimer's.
Mutations in Donors' Stem Cells May Cause Problems for Cancer Patients
Washington University in St. Louis
A new study from Washington University School of Medicine in St. Louis suggests that extremely rare, harmful genetic mutations present in healthy donors' stem cells -- though not causing health problems in the donors -- may be passed on to cancer patients receiving stem cell transplants, potentially creating health problems for the recipients. Among the concerns are heart damage, graft-versus-host disease and possible new leukemias.
Robert Amdur, MD, named Editor in Chief of Practical Radiation Oncology
American Society for Radiation Oncology (ASTRO)
The American Society for Radiation Oncology (ASTRO) announced today that Robert Amdur, MD, will become the new Editor in Chief of Practical Radiation Oncology, ASTRO's clinical practice journal. Dr. Amdur, a professor of radiation oncology at the University of Florida College of Medicine, will begin his five-year term on January 1, 2021.
Multimodal Genomic Analyses Predict Response to Immunotherapy in Lung Cancer Patients
Johns Hopkins Medicine
Researchers at Johns Hopkins Kimmel Cancer Center, the Bloomberg~Kimmel Institute for Cancer Immunotherapy and the Johns Hopkins University School of Medicine have developed an integrated genomic approach that potentially could help physicians predict which patients with nonsmall cell lung cancer will respond to therapy with immune checkpoint inhibitors.
Unfruitful: Eating More Produce Will Not Cure, Stop Prostate Cancer
University of California San Diego Health
University of California San Diego School of Medicine researchers report that patients with prostate cancer assigned to eat seven or more servings of vegetables and fruits daily saw no extra protection from the increased consumption of micronutrients, running contrary to current thought.
Memorial Sloan Kettering Appoints Roxanne Taylor as Chief Marketing and Communications Officer
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center has appointed Roxanne Taylor as Chief Marketing and Communications Officer, effective February 3. In this role, Ms. Taylor will be responsible for shaping and enhancing the MSK brand and will be accountable for building the long-term equity of the brand with all stakeholders.
Lung Cancer Expert to Head Medical Oncology at Cedars-Sinai
Cedars-Sinai
Prominent lung cancer expert Karen L. Reckamp, MD, MS, has been selected to be director of the Division of Medical Oncology at Cedars-Sinai Cancer. Reckamp also will serve as medical oncology director of the Women's Guild Lung Institute in Cedars-Sinai's Department of Medicine and associate director for Clinical Research at Cedars-Sinai Cancer.
NUS researchers discover breakthrough in cancer diagnosis using big data analytics
National University of Singapore
A team of researchers from the National University of Singapore has developed a personalised assessment tool which can detect the incidence of cancer, predict patient survivability and determine patient suitability for immunotherapy cancer treatment.
Douglas Hanahan Appointed Distinguished Scholar of the Ludwig Institute for Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research is pleased to announce the appointment of Douglas Hanahan as a Distinguished Scholar at the Lausanne Branch of the Ludwig Institute for Cancer Research.
John Theurer Cancer Center Investigators Report Effectiveness of New Treatment for Refractory Multiple Myeloma
Hackensack Meridian Health
Investigators at John Theurer Cancer Center at Hackensack University Medical Center in New Jersey were part of the CANDOR global phase III clinical trial for patients with refractory (persistent) multiple myeloma. The study was selected as the prestigious plenary presentation at the 61st American Society of Hematology (ASH) Annual Meeting, the world's leading conference for hematologic cancers and blood disorders, held in Orlando in December.
Updated Breast Cancer Guideline Refines Testing to Better Identify Patients Likely to Benefit from Treatment
College of American Pathologists (CAP)
The College of American Pathologists (CAP) and the American Society of Clinical Oncology (ASCO),have updated the guideline for estrogen and progesterone receptor (ER/PgR) testing in breast cancer.
Machine keeps human livers alive for one week outside of the body
University of Zurich
Researchers from the University Hospital Zurich, ETH Zurich, Wyss Zurich and the University of Zurich have developed a machine that repairs injured human livers and keeps them alive outside the body for one week.
How Marijuana Accelerates Growth of HPV-related Head and Neck Cancer Identified
University of California San Diego Health
University of California San Diego School of Medicine researchers identified how THC from marijuana accelerates cancer growth in patients with human papillomavirus (HPV)-positive head and neck cancer.
Brain Cancer Expert Joins Neurosurgery Faculty at Mount Sinai
Mount Sinai Health System
Dolores Hambardzumyan, PhD, MBA, has been appointed Senior Faculty in the Department of Neurosurgery and a member of The Tisch Cancer Institute at the Icahn School of Medicine at Mount Sinai.
Investigational drugs block bone loss in mice receiving chemotherapy
Washington University in St. Louis
Studying mice, researchers from Washington University School of Medicine in St. Louis have found a driver of bone loss related to cancer treatment -- cellular senescence. This process is independent of hormones related to bone health, such as estrogen. Such bone loss can be stopped by treating the mice with either of two investigational drugs already being evaluated in clinical trials.
Dana-Farber Cancer Institute to Establish Riney Family Multiple Myeloma Initiative
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute will establish the Riney Family Multiple Myeloma Initiative to help improve outcomes and accelerate understanding of the underlying biology for the most challenging types of myelomas, cancers that form in a type of white blood cell called a plasma cell.
Scientists identify protein associated with ovarian cancer that exacerbates neurodegeneration in Alzheimer's
Houston Methodist
Houston Methodist scientists identified a protein found in ovarian cancer that may contribute to declining brain function and Alzheimer's disease, by combining computational methods and lab research.
Grant to help UniSA researchers develop personalised cancer treatment
University of South Australia
Personalised cancer treatment is one step closer to becoming a reality for more patients, thanks to a Cancer Council Beat Cancer Project grant awarded to University of South Australia researcher Dr Stephanie Reuter Lange to explore how computer-based modelling can optimise cancer treatment and remove the need for expensive clinical trials.
Sanft named Chief Patient Experience Officer at Smilow Cancer Hospital
Yale Cancer Center
Tara Sanft, M.D., associate professor of Medicine (Medical Oncology) and Director of the Smilow Cancer Hospital (SCH) Survivorship Clinic, has been appointed the inaugural Chief Patient Experience Officer at Yale Cancer Center (YCC) and SCH at Yale New Haven Hospital.
Mougalian appointed Deputy Chief Ambulatory Officer at Smilow Cancer Hospital
Yale Cancer Center
Sarah Mougalian, M.D., assistant professor of Medicine (Medical Oncology) has been named the inaugural Deputy Chief Ambulatory Officer at Smilow Cancer Hospital (SCH) at Yale New Haven Hospital.
Expert Offers Insight on Sneaky Signs of Cervical Cancer
Mercy Medical Center
Researchers create framework for evaluating how fast a cancer will grow
University of California, Los Angeles (UCLA), Health Sciences
An international team of researchers led by UCLA's Paul Boutros, have created a new way to accurately estimate how fast an individual cancer is evolving using open-source software.
First-Ever Genomic Study of Puberty Yields Insights into Development, Cancer, and Infertility
Huntsman Cancer Institute at the University of Utah
In the first-ever genome-scale analysis of the puberty process in humans, researchers at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) outline distinct and critical changes to stem cells in males during adolescence.
John Theurer Cancer Center Announces Appointment of Five New Physicians
Hackensack Meridian Health
Five new physicians have joined the medical staff at John Theurer Cancer Center at Hackensack University Cancer Center in New Jersey:
Study finds salt nanoparticles are toxic to cancer cells
University of Georgia
A new study at the University of Georgia has found a way to attack cancer cells that is potentially less harmful to the patient.
New research identifies obstacles to early detection of skin cancer in rural western states
Texas State University
Residents of rural, sparsely-populated "frontier counties" in the Western U.S. face higher incidents of skin cancer and related mortality rates.
University of Colorado Cancer Center named National Pancreas Foundation Center of Excellence
University of Colorado Cancer Center
Due in part to advanced surgical techniques, more effective medicines, and a multidisciplinary approach to treating the disease, University of Colorado Cancer Center is able to operate on 30+ percent of pancreatic cancer patients, nearly double the national average.
Surgery May Add Months or Years of Survival For Adults With Rare And Deadly Brain Cancers
Johns Hopkins Medicine
For adult patients with brainstem high-grade gliomas -- one of the rarest and deadliest forms of brain cancer -- surgically removing the entire tumor may add many months or potentially years of survival beyond that offered by radiation and chemotherapy, according to results of a medical records study led by researchers at the Johns Hopkins Kimmel Cancer Center.
Ping-Chih Ho Appointed Associate Member of Ludwig Institute for Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research congratulates Ping-Chih Ho on his appointment as Associate Member at the Lausanne Branch of the Ludwig Institute for Cancer Research.
Common Indian Fruit Shows Promise as a Cancer Fighter
Saint Louis University
According to recent research, the Asian fruit commonly eaten in India that also is known as bitter melon has properties that prevent cancer from growing and spreading. It also shows promise in slowing the progression of cancer, which is the world's second deadliest disease.
Plant-derived SVC112 hits cancer stem cells, leaves healthy cells alone
University of Colorado Cancer Center
Study shows Colorado drug SVC112 stops production of proteins that cancer stem cells need to survive and grow
Nanoparticles Deliver 'Suicide Gene' Therapy to Pediatric Brain Tumors Growing in Mice
Johns Hopkins Medicine
Johns Hopkins researchers report that a type of biodegradable, lab-engineered nanoparticle they fashioned can successfully deliver a "suicide gene" to pediatric brain tumor cells implanted in the brains of mice. The poly(beta-amino ester) nanoparticles, known as PBAEs, were part of a treatment that also used a drug to kill the cells and prolong the test animals' survival.
Study shows protein inhibitor as potential treatment approach for common mutations found in non-Hodgkin lymphomas
University of Texas M. D. Anderson Cancer Center
Study shows protein inhibitor as potential treatment approach for common mutations found in non-Hodgkin lymphomas. Findings may create immunotherapy options for lymphomas caused by CREBBP mutations.
Researchers Surprised by High Levels of Alcohol Consumption among Cancer Survivors
National Comprehensive Cancer Network(r) (NCCN(r))
New research JNCCN--Journal of the National Comprehensive Cancer Network, using data from NHIS to examine self-reported drinking habits among people reporting a cancer diagnosis, finds 56.5% were current drinkers, 34.9% exceeded moderate drinking levels, and 21% engaged in binge drinking.
Fred Hutch names Dr. Thomas J. Lynch Jr. as new president and director
Fred Hutchinson Cancer Research Center
Fred Hutchinson Cancer Research Center announced today that Dr. Thomas J. Lynch Jr. will become the center's new president and director. Lynch, a well-known cancer leader with expertise in solid tumor research, precision medicine and immuno-oncology, will join Fred Hutch Feb. 1.
Ultrasound Selectively Damages Cancer Cells When Tuned to Correct Frequencies
American Institute of Physics (AIP)
Doctors have used focused ultrasound to destroy tumors without invasive surgery for some time. However, the therapeutic ultrasound used in clinics today indiscriminately damages cancer and healthy cells alike. Researchers have now developed a low-intensity ultrasound approach that exploits the properties of tumor cells to target them and provide a safer option. Their findings, reported in Applied Physics Letters, are a new step in oncotripsy, the singling out and killing of cancer cells based on their physical properties.
Dana-Farber Cancer Institute to Establish Chen-Huang Center for EGFR Mutant Lung Cancers
Dana-Farber Cancer Institute
Dana-Farber Cancer Institute will create the Chen-Huang Center for EGFR (epidermal growth factor receptor) Mutant Lung Cancers to stimulate research, promote clinical trials, and strengthen the Institute's capabilities for studying and treating lung cancer.
Study reveals a new approach to enhancing response to immunotherapy in melanoma
Sanford Burnham Prebys Medical Discovery Institute
Scientists at Sanford Burnham Prebys have identified a new way to boost the immune system's ability to fight cancer. The study used a mouse model to identify the importance of the Siah2 protein in the control of immune cells called T regulatory cells (Tregs), which limit the effectiveness of currently used immunotherapies. The research, which offers a new avenue to pursue immunotherapy in cases where the treatment fails, was published today in Nature Communications.
Can the flu shot help fight cancer?
Rush University Medical Center
Physicians and scientists at Rush University Medical Center have found that injecting tumors with influenza vaccines, including some FDA-approved seasonal flu shots, turns cold tumors to hot, a discovery that could lead to an immunotherapy to treat cancer. The study results were published December 30th in the Proceedings of the National Academy of Sciences.
Scientists Map Structural Proteins Across an Ovary, Another Step Toward "Ink" Development for 3-D Printing a Bioprosthetic Ovary
Ann and Robert H. Lurie Children's Hospital of Chicago
For the first time, scientists identified and mapped the location of structural proteins in a pig ovary. Ongoing development of an "ink" with these proteins will be used for 3-D printing an artificial (or bio-prosthetic) ovary that could be implanted and allow a woman to have a child. Findings were recently published in Scientific Reports.
AACI Marks Milestone with New Member Cold Spring Harbor Laboratory
Association of American Cancer Institutes (AACI)
Cold Spring Harbor Laboratory Cancer Center, one of seven National Cancer Institute-designated basic laboratory cancer centers, is the newest and 100th member of the Association of American Cancer Institutes.
Women with single dose of HPV vaccine gain similar protection as multiple doses
University of Texas Health Science Center at Houston
A new study revealed that one dose of the HPV vaccine may prevent infection from the potential cancer-causing virus, according to research published in JAMA Network Open from The University of Texas Health Science Center at Houston (UTHealth).
Researchers Identify New Therapeutic Target for Colorectal Cancer
The Rockefeller University Press
Researchers at the University of Toronto have identified a key protein that supports the growth of many colorectal cancers. The study, which will be published December 27 in the Journal of Cell Biology, reveals that a protein called Importin-11 transports the cancer-causing protein βcatenin into the nucleus of colon cancer cells, where it can drive cell proliferation. Inhibiting this transport step could block the growth of most colorectal cancers caused by elevated βcatenin levels.
Yale Cancer Center launches Center for Community Engagement and Health Equity
Yale Cancer Center
Yale Cancer Center (YCC) announces the launch of the Center for Community Engagement and Health Equity (CEHE). Building on YCC's longstanding commitment to high-quality, expert, and patient-centered cancer care, screening, and prevention across the state of Connecticut, the new Center is dedicated to ensuring cancer health equity and improving outcomes with an emphasis on traditionally underserved neighborhoods.
Proton Therapy Lowers Risk of Side Effects in Cancer Patients Compared to Traditional Radiation
Perelman School of Medicine at the University of Pennsylvania
Proton therapy leads to significantly lower risk of side effects severe enough to lead to unplanned hospitalizations for cancer patients when compared with traditional radiation, while cure rates between the two groups are almost identical
U-M Approach Could Improve the Accuracy of Cancer Clinical Trials
Michigan Medicine - University of Michigan
An innovative approach to analyzing the medical scans of patients in clinical trials could help ensure the accuracy of trial results while reducing the workload for busy oncologists, according to a new study by researchers at the University of Michigan Rogel Cancer Center.
Breaking the dogma: Key cell death regulator has more than one way to get the job done
St. Jude Children's Research Hospital
Scientists at St. Jude Children's Research Hospital have discovered a new way that the molecule RIPK1 leads to cell death in infected, damaged or unwanted cells showing that more than one mechanism can trigger the process. The findings appeared online today in the Journal of Experimental Medicine.
Science Snapshots From Berkeley Lab
Lawrence Berkeley National Laboratory
This edition of Science Snapshots highlights the discovery of an investigational cancer drug that targets tumors caused by mutations in the KRAS gene, the development of a new library of artificial proteins that could accelerate the design of new materials, and new insight into the natural toughening mechanism behind adult tooth enamel.
Clinical trials planned for brain tumor 'GPS' maps
Case Western Reserve University
A GPS map to guide neural navigation devices developed by a Case Western Reserve University cancer researcher has shown 90% accuracy in pinpointing brain tumors and will soon be tested in real time with patients at Cleveland Clinic under a three-year, $600,000 V Foundation grant.
The Wistar Institute Received Nearly $2.5M in Philanthropic Support
Wistar Institute
In the past six months, scientists at The Wistar Institute received funding from private foundations totaling $2,418,000 that will fuel new discoveries in cancer, immunology and infectious diseases.
Opioid Self-management Practices and Potential Safety Risks Among Patients with Cancer
University of Pennsylvania School of Nursing
Despite a national opioid crisis, prescribed opioid analgesics remain a viable option for pain management for patients with cancer. In effect, patients with cancer represent one of the few groups excluded from most state legislation and policy initiatives on prescribing opioids as well as from opioid stewardship programs of many health systems. However, little is understood about oncology patients' opioid self-management practices and potential safety risk that may stem from these practices.
New Therapeutic Strategy for Chemotherapy Resistance in Ovarian Cancer
Wistar Institute
A Wistar study demonstrated that NAMPT, an enzyme critical for NAD+ biosynthesis, mediates selection of stem-like chemoresistant cells following cisplatin treatment.
Backed by Yale Cancer Center research, FDA approves new drug for advanced bladder cancer
Yale Cancer Center
The U.S. Food & Drug Administration (FDA) granted accelerated approval to the drug enfortumab vedotin (EV) to treat adult patients with advanced urothelial or bladder cancer.
CRI scientists discover metabolic feature that allows melanoma cells to spread
UT Southwestern Medical Center
Researchers at Children's Medical Center Research Institute at UT Southwestern (CRI) have uncovered why certain melanoma cells are more likely to spread through the body.
A Decade in Review: 7 Healthcare Breakthroughs
University of California, Los Angeles (UCLA), Health Sciences
UCLA Health experts weigh in on the most significant healthcare advances of the last ten years and what exciting developments we can look forward to in the decade ahead.
Cancer therapy may be aided by induced macropinocytosis, a rarely reported form of cell death
University of Alabama at Birmingham
A metabolic inhibitor was able to kill human cancer cells of the skin, breast, lung, cervix and soft tissues through a non-apoptotic route -- catastrophic macropinocytosis. The inhibitor acted synergistically with the chemotherapy drug, cyclophosphamide, in mouse xenografts to reduce tumor growth.
Bonni Lee Guerin, MD Honored By American Cancer Society - Northeast Region
Atlantic Health System
Bonni Lee Guerin, MD, hematologist/oncologist and physician researcher at Overlook Medical Center, was honored by the American Cancer Society for her role in advancing breast cancer treatment and prevention. In addition to her forward-looking clinical approach, Dr. Guerin is the principal investigator (PI) of numerous clinical trials exploring new ways to incorporate the latest advances in the management of breast cancer. Dr. Guerin was PI at Atlantic Health System, with the largest number of study participants of any center in the New York-New Jersey metro area, for the landmark TAILORx clinical trial.
New Pediatric Cancer Guidelines Published by National Comprehensive Cancer Network Focus on Improving Long-Term Outcomes Worldwide
National Comprehensive Cancer Network(r) (NCCN(r))
NCCN publishes new NCCN Guidelines for treating children, adolescents and young adults with pediatric aggressive mature B-cell lymphomas (common and curable forms of non-Hodgkin lymphoma), including Burkitt lymphoma and diffuse large B-cell lymphoma.
Case Western Reserve researchers to lead Northeast Ohio initiative to prevent, detect and treat lung cancer in underserved communities
Case Western Reserve University
With a $2.75 million, three-year grant from the Bristol-Myers Squibb (BMS) Foundation, researchers from Case Western Reserve University will lead a community wide initiative to create and apply innovative methods to prevent and detect lung cancer in underserved residents in Northeast Ohio.
Microscopic World Comes Alive During Nikon Small World Exhibit
Wistar Institute
See cellular images as distinct as abstract art, minerals appear as future urban landscapes, single-celled organisms of the microscopic netherworld, and much more from the 2019 Nikon Small World competition of photomicrography.
ASCO elects UChicago Medicine's Vokes as president-elect
University of Chicago Medical Center
The American Society of Clinical Oncology (ASCO) has elected Everett Vokes, MD, Chair of the Department of Medicine at the University of Chicago Medicine, to serve as its president for the 2021-22 term and Tara Henderson, MD, MPH, Associate Professor of Pediatrics, to serve as the designated pediatric oncologist on its Board of Directors for the 2020-24 term.
Virginia Mason Experts Assess Breath Test to Detect Esophageal Cancer
Virginia Mason Medical Center
Research is beginning at Virginia Mason Medical Center that will evaluate the accuracy of a breath test for detecting esophageal cancer, one of the fastest growing and deadliest cancers in the United States.
Math Equation Predicts and Detects Liver Cancer
University of California San Diego Health
University of California San Diego School of Medicine and Moores Cancer Center researchers developed a math equation to predict and detect liver cancer and identified when healthy cells become cancerous.
Elizabeth Fox, M.D., named senior vice president of clinical trials research
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital announced today that Elizabeth Fox, M.D., has been named senior vice president of clinical trials research.
Novel Cell-Based Therapy Induces Cell Death in Sensitive and Resistant Non-Hodgkin Lymphoma Models
Rutgers Cancer Institute of New Jersey
Investigators at Rutgers Cancer Institute of New Jersey have found that a treatment based on a novel cellular product programmed to deliver an overabundance of chimeric antigen receptor causes cell death in non-Hodgkin lymphoma models that are sensitive or resistant to standard therapies.
Breast biopsies after neoadjuvant chemotherapy accurately predict presence of residual breast cancer
University of Texas M. D. Anderson Cancer Center
Researchers from The University of Texas MD Anderson Cancer Center have identified a standardized protocol that uses image-guided breast biopsies to reliably predict residual disease in breast cancer patients and that potentially identifies exceptional responders who may not require surgery.
Residual cancer burden after neoadjuvant therapy can accurately predict breast cancer survival
University of Texas M. D. Anderson Cancer Center
Researchers from The University of Texas MD Anderson Cancer Center today reported results from a pooled analysis of more than 5,100 breast cancer patients that found residual cancer burden (RCB) continuous index and classification were independently and strongly prognostic for all breast cancer phenotypes.
Analysis of Different Treatment Strategies for Non-Invasive Breast Cancer Shows Radiation Treatment Alone is Cost-Effective
Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey investigators evaluated all treatment strategies for both standard-risk and good-risk ductal carcinoma in-situ and found the most commonly recommended combination treatment for DCIS represents low-value care, while radiation therapy alone was cost-effective.
Jersey Shore University Medical Center Receives Re-Accreditation from the National Accreditation Program for Breast Centers
Hackensack Meridian Health
Hackensack Meridian Health Jersey Shore University Medical Center achieved re-accreditation from the National Accreditation Program for Breast Centers (NAPBC), a program administered by the American College of Surgeons.
Adding tucatinib to drug combination extends survival for advanced HER2+ breast cancer patients
University of Texas M. D. Anderson Cancer Center
Researchers from The University of Texas MD Anderson Cancer Center today reported study results showing the addition of tucatinib to capecitabine (Xeloda) and trastuzumab (Herceptin) significantly improved progression-free survival (PFS) and overall survival (OS) in patients with advanced HER2-positive breast cancer, with and without brain metastasis according to results of the HER2CLIMB clinical trial.
Researchers create accurate model of organ scarring using stem cells in a lab
University of California, Los Angeles (UCLA), Health Sciences
A team led by Dr. Brigitte Gomperts at UCLA has developed a "scar in a dish" model that uses multiple types of cells derived from human stem cells to closely mimic the progressive scarring that occurs in human organs. The researchers used this model to identify a drug candidate that stopped the progression of and even reversed fibrosis in animal models.
A New Era of Care: The David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center to Open in January 2020
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK) today celebrated the opening of a $1.5 billion state-of-the-art cancer treatment facility with government officials, members of the Boards of Overseers and Managers, and staff. Opening for patient care next month, the 750,000-square-foot building is the institution's -- and the city's -- largest freestanding cancer care facility. The David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center is a healing community dedicated to patient-centered care, made possible by a landmark donation and a pioneering vision that signifies a new era of cancer care.
Yale Cancer Center researchers investigate inducing "synthetic lethality" in two blood and bone cancers
Yale Cancer Center
In a clinical trial led by Yale Cancer Center (YCC) and Smilow Cancer Hospital, researchers aim to exploit DNA mutations in the treatment of two blood and bone marrow cancers, a different tacit than the more traditional approach of blunting or switching off genetic mutations linked to cancer
ASH: Research revises classification of acute myeloid leukemia and myelodysplastic syndrome
St. Jude Children's Research Hospital
Results from a study conducted by St. Jude Children's Research Hospital and the Munich Leukemia Laboratory were presented today as a late-breaking abstract at the American Society of Hematology annual meeting. The study integrates genomic and transcriptomic sequencing to provide the most detailed classification of acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) to date.
Small Mutations Identified through Deep DNA Sequencing for AML and MDS
Rutgers Cancer Institute of New Jersey
Deep DNA sequencing analysis conducted by Rutgers Cancer Institute of New Jersey investigators examining genomic differences within tumors for prediction of disease relapse in certain hematologic malignancies has identified small mutations. These may help further guide treatment decision making for patients.
Retrospective Analysis Shows Proton Therapy Well Tolerated in Patients Undergoing Breast Conserving Surgery
Rutgers Cancer Institute of New Jersey
Investigators at Rutgers Cancer Institute of New Jersey conducted a retrospective review of patients treated with proton therapy following breast-conserving surgery and found acceptable toxicity rates along with good-to-excellent patient-reported cosmetic outcomes.
Giving Common Antibiotic Before Radiation May Help Body Fight Cancer
Perelman School of Medicine at the University of Pennsylvania
The antibiotic vancomycin alters the gut microbiome in a way that can help prime the immune system to more effectively attack tumor cells after radiation therapy
Yale Cancer Center study suggests new approaches needed to manage ibrutinib-related toxicities in CLL patients
Yale Cancer Center
New findings by Yale Cancer Center (YCC) and Smilow Cancer Hospital researchers show that as the use of the drug ibrutinib climbs in patients with chronic lymphocytic leukemia (CLL), so do the rates of patients who stop taking the drug.
Treatment with PD-1 inhibitor prior to stem cell transplant is safe, effective for patients with classic Hodgkin lymphoma, study finds
Dana-Farber Cancer Institute
A new analysis shows that a donor stem cell transplant following treatment with an immune checkpoint inhibitor is generally safe and produces good outcomes for patients with Hodgkin lymphoma.
CAR T-cell therapy effective for relapsed mantle cell lymphoma patients
University of Texas M. D. Anderson Cancer Center
A one-year follow-up study revealed a majority of patients with mantle cell lymphoma resistant to prior therapies may benefit from treatment with CD19-targeting chimeric antigen receptor (CAR) .
New software tool uses AI to help doctors identify cancer cells
UT Southwestern Medical Center
UT Southwestern researchers have developed a software tool that uses artificial intelligence to recognize cancer cells from digital pathology images - giving clinicians a powerful way of predicting patient outcomes.