Filters:
NETRF Announces New Grants for Neuroendocrine Cancer Research
NET (Neuroendocrine Tumor) Research Foundation
Nonprofit NET Research Foundation announces grants up to $1.2 million for neuroendocrine tumor research (to fund basic, translational, or clinical studies) to improve care for uncommon cancer type.
Indestructible Virus Yields Secret to Creating Incredibly Durable Materials
University of Virginia Health System
It lives in boiling acid that dissolves flesh and bone. Now scientists have unlocked the secrets of the indestructible virus, potentially allowing them to harness its remarkable properties to create super-durable materials and better treat disease.
McCain's Form of Cancer Challenges Treatment, Virginia Tech Researchers Say
Virginia Tech
Micro- and Nanotechnologies for Quantitative Biology and Medicine
SLAS (Society for Laboratory Automation and Screening)
Ten new reviews and original research reports that illustrate how the progression of research assays from qualitative outputs toward increasingly sensitive quantitative outputs is transforming life sciences and biomedical research and diagnostics by improving the ability of researchers and clinicians to detect and quantify increasingly complex assays.
Fred Hutch Glioblastoma Experts Available to Discuss Diagnosis, Treatment Options and the Latest Research
Fred Hutchinson Cancer Research Center
CIRM Approves $5.8 Million Grant for CAR-T Therapy That Targets Cancer Stem Cells
University of California San Diego Health
The Independent Citizens Oversight Committee of the California Institute for Regenerative Medicine (CIRM) today unanimously approved a $5.8 million award to University of California San Diego School of Medicine researchers to develop a new immunotherapy in which patients' cells would be equipped with a special receptor that recognizes and targets cancer stem cells, whose survival abilities often render standard therapies ineffective or short-term.
Pathologist Expert: Precision Medicine Could Still Deliver Good News for Sen. McCain
College of American Pathologists (CAP)
Maciej Lesniak, MD, Neurosurgeon @NorthwesternMed Is Available to Discuss Sen. McCain's Brain Tumor Diagnosis.
Northwestern Medicine
Concurrent Chemotherapy, Proton Therapy Improves Survival in Patients with Advanced Lung Cancer
University of Texas M. D. Anderson Cancer Center
For patients with advanced, inoperable stage 3 lung cancer, concurrent chemotherapy and the specialized radiation treatment, proton therapy, offers improved survival compared to historical data for standard of care, according to a new study from The University of Texas MD Anderson Cancer Center.
Cedars-Sinai Brain Tumor Expert Available to Discuss Diagnosis and the Latest Treatment Options for Glioblastoma and Other Brain Cancers
Cedars-Sinai
UC Davis-Led Group Receives $17 Million in NCI Funds
UC Davis Comprehensive Cancer Center
Breast Cancer Surveillance Consortium (BCSC) investigators have received a $17 million program project grant renewal from the National Cancer Institute to study the effectiveness of different breast cancer screening and surveillance strategies using digital mammography, digital breast tomosynthesis (3D mammography), and breast MRI. Co-led by UC Davis researcher Diana Miglioretti, the consortium seeks to ensure that women get personalized care based on their individual risk and preferences.
Hold Your Breath and Spare Your Heart
Valley Health System
"Take a deep breath and hold it." With that simple instruction, The Department of Radiation Oncology at Valley-Mount Sinai Comprehensive Cancer Care is helping patients with breast cancer protect their heart health.
Penn Study Suggests that Combining CAR T Cells with Existing Immunotherapies May Overcome Resistance in Glioblastomas
Perelman School of Medicine at the University of Pennsylvania
Genetically modified "hunter" T cells successfully migrated to and penetrated a deadly type of brain tumor known as glioblastoma (GBM) in a clinical trial of the new therapy, but the cells triggered an immunosuppressive tumor microenvironment and faced a complex mutational landscape that will need to be overcome to better treat this aggressive cancer, Penn Medicine researchers report in a new study this week in Science Translational Medicine.
Henry Ford Treats World's First Patient Using New MRI-Guided Radiation Therapy that Simultaneously Tracks, Treats Tumor
Henry Ford Health System
The Henry Ford Cancer Institute has treated the world's first cancer patient today with an advanced radiation therapy that uses an FDA-cleared real-time magnetic resonance imaging and linear accelerator delivery for more precise and accurate radiation treatment.
New Study Finds That Lymph Node Removal Isn't Necessary For All Melanoma Patients
Intermountain Medical Center
Many patients with melanoma need a sentinel-lymph-node biopsy to determine if cancer cells have spread there, but a positive finding doesn't mean all the lymph nodes in the area must be removed, according to a new international study.
Comparing Algorithms That Search for Cancer Mutations
Sanford Burnham Prebys Medical Discovery Institute
Scientists team up to evaluate the tools used to probe the cancer genome
FDA Gives A Nod To "Paradigm Shifting" Cancer Treatment
Yale Cancer Center
A key committee for the U.S. Food and Drug Administration issued a first-of-its-kind recommendation this week, unanimously signing off on an experimental cancer treatment
San Diego County Volunteer Selected as 2017 ASTRO Survivor Circle Award Winner
American Society for Radiation Oncology (ASTRO)
The winner of the American Society for Radiation Oncology's (ASTRO's) 2017 Survivor Circle Award is many things--a former pro baseball player, a retired UPS driver, a family man and, yes, a current cancer patient.
Bacteria Actively Drive Development of Colorectal Cancer
Texas A&M University
Colorectal cancer is fairly treatable when caught early with regular screenings, but it is still the second-leading cause of cancer-related deaths in American men and the third-leading cause in women.
New Chief Nursing Officer Named at Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey
Janet Gordils-Perez, DNP, RN, ANP-BC, AOCNP, from Plainsboro Township, has been named Chief Nursing Officer at Rutgers Cancer Institute of New Jersey. She was recently promoted from her position as Director of Oncology Nursing. Dr. Gordils-Perez came to Rutgers Cancer Institute in 2004 from Memorial Sloan-Kettering Cancer Center, where she was an adult nurse practitioner and a clinical research nurse.
Appropriate Distress Screening and Follow Up Leads to Fewer ER Visits and Hospitalizations in Patients with Cancer, Study Finds
National Comprehensive Cancer Network(r) (NCCN(r))
As published in JNCCN, a University of Michigan Comprehensive Cancer Center study found that adherence to distress screening protocols set by the Commission on Cancer could lead to 18% fewer ER visits and 19% fewer hospitalizations.
First Michigan Proton Center Begins Treating Cancer Patients
Beaumont Health
Proton therapy is a high-tech alternative to X-ray radiation. It offers greater precision to destroy cancerous cells, sparing adjacent healthy tissue with fewer side effects. Proton therapy uses atomic particles, traveling up to two-thirds the speed of light, to fight cancer. Beaumont's center is one of just 25 operational proton therapy centers in the U.S.
Genetically Enhanced, Cord-Blood Derived Immune Cells Strike B-Cell Cancers
University of Texas M. D. Anderson Cancer Center
Immune cells with a general knack for recognizing and killing many types of infected or abnormal cells also can be engineered to hunt down cells with specific targets on them to treat cancer, researchers at The University of Texas MD Anderson Cancer Center report in the journal Leukemia
Surgery for Early Prostate Cancer May Not Save Lives
Washington University in St. Louis
A major 20-year study provides further evidence that prostate cancer surgery offers negligible benefits to many men with early-stage disease. In such men, who account for most cases of newly diagnosed prostate cancer, surgery did not prolong life and often caused serious complications such as infection, urinary incontinence and erectile dysfunction. The research team included Washington University School of Medicine in St. Louis.
Tumor-Targeting Drug Shows Potential for Treating Bone Cancer Patients
University of Texas M. D. Anderson Cancer Center
The treatment of osteosarcoma, the most common tumor of bone, is challenging. A study led by The University of Texas MD Anderson Cancer Center found a drug known as bone metastasis-targeting peptidomimetic (BMTP-11) has potential as a new therapeutic strategy for this devastating illness.
Blood Test for Early Detection of Pancreatic Cancer Headed to Clinic
Perelman School of Medicine at the University of Pennsylvania
A newly identified biomarker panel could pave the way to earlier detection and better treatment for pancreatic cancer. Currently over 53,000 people in the United States are diagnosed with pancreatic cancer -- the fourth leading cause of cancer death -- every year. The blood biomarkers correctly detected pancreatic cancer in blood samples from patients at different stages of their disease.
How People of Color Can Prevent and Detect Skin Cancer
American Academy of Dermatology
With summer in full swing, dermatologists from the American Academy of Dermatology are reminding everyone that people of all races and colors can develop skin cancer. Although people of color have a lower risk of developing skin cancer than Caucasians, when skin cancer develops in people of color, it is often diagnosed at a more advanced stage - making it more difficult to treat. The good news, say dermatologists, is that there is a lot people can do to protect their skin and reduce their risk of getting skin cancer, including melanoma, the deadliest form.
Experimental "Enhancer" Drug May Boost Conventional Therapies for Deadly Pediatric Brain Cancers
Johns Hopkins Medicine
Laboratory studies suggest that an experimental drug already in early clinical trials for a variety of adult cancers might enhance radiation and chemotherapy for two childhood brain cancers that currently are virtually always fatal.
NEJM Case Reports Show Promise of Cancer Immunotherapy to Treat Rare Lymphoma
University of Colorado Cancer Center
Three case reports published in the New England Journal of Medicine demonstrate the promise of cancer immunotherapy in gray zone lymphoma, potentially paving the way for clinical trials utilizing this strategy in this and related conditions.
Detroit Pediatric Oncologist Leads Largest Single Study on Survival Outcomes for Children with Down Syndrome and AML or ALL
Children's Hospital of Michigan
Jeffrey W. Taub, M.D., FAAP, chief, Division of Oncology, at the DMC's Children's Hospital of Michigan was the principal investigator of the study, which enrolled 204 children from 2007-2011 through the Children's Oncology Group (COG), an international organization which links all major pediatric oncology centers in the U.S., Canada and other countries to develop treatments for children with cancer.
NYU Langone Launches Major Interdisciplinary Program Targeting Pancreatic Cancer
NYU Langone Medical Center
Perlmutter Cancer Center at NYU Langone has announced the creation of a multidisciplinary center of excellence to develop innovative approaches to diagnose, treat and prevent pancreatic cancer.
Combo Immunotherapy May Herald New Standard of Care for Kidney Cancer
UT Southwestern Medical Center
Combination therapy with two immunotherapy drugs produces an unprecedented doubling of response rates from 20 percent to 40 percent, a new study shows.
Bringing Precision to Medicare Cancer Care
Harvard Medical School
At a glance: Medicare policies governing end-of-life care for cancer patients may fail to reflect the variety of experiences across different patient subgroups. Researchers have developed a model that accounts for variations in the clinical course, outcomes and patterns of care among patients with the same cancer diagnosis. Stratification of different subpopulations could lead to better tailored Medicare policies that take into account critical differences in end-of-life care.
First Large-Scale Genomic Analysis of Key Acute Leukemia Will Likely Yield New Therapies
St. Jude Children's Research Hospital
Charting the genomic landscape of T-lineage acute lymphoblastic leukemia patients revealed insights that will guide research and help to lay the foundation for more targeted therapy.
Fred Hutch Elects Former Executives From CNN, Gates Foundation and Microsoft as Trustees
Fred Hutchinson Cancer Research Center
Fred Hutchinson Cancer Research Center's board of trustees yesterday elected three new members, adding expertise in information technology, media and global health as it works to accelerate efforts to develop cures for cancer and other diseases.
Penn Gastroenterologists Receive Funding to Continue Research Partnership on Barrett's Esophagus
Perelman School of Medicine at the University of Pennsylvania
A research group in the division of Gastroenterology in the Perelman School of Medicine at the University of Pennsylvania has received a National Cancer Institute grant to extend a Barrett's Esophagus translational research network with Columbia University and the Mayo Clinic until 2022.
How Family and Friends Influence Breast Cancer Treatment Decisions
Michigan Medicine - University of Michigan
When a woman walks into the oncologist's office, she's usually not alone. In fact, a new study finds that half of women have at least three people standing behind them, sitting next to them or waiting at home to help.
Researchers Propose New Approach to Identify Genetic Mutations in Men with Prostate Cancer
University of Utah Health
Scientists have had limited success at identifying specific inherited genes associated with prostate cancer. Researchers at University of Utah Health studied prostate cancer patients with multiple cancer diagnoses to identify genetic mutations that may influence cancer treatment and cancer risk.
Micron-Sized Hydrogel Cubes Show Highly Efficient Delivery of a Potent Anti-Cancer Drug
University of Alabama at Birmingham
Researchers have developed micro-cubes that can sponge up a hydrophobic anti-cancer drug and deliver it to cancer cells. Tissue culture tests show these tiny, porous cubes, loaded with the hydrophobic drug, are more potent against liver cancer cells and less harmful to normal liver cells.
Fight CRC and Cancer Research Institute Award $400,000 to Support Cutting-Edge Immunotherapy Research in Colorectal Cancer
Cancer Research Institute
$400k grant to Johns Hopkins University School of Medicine investigator Cynthia Sears will carry out research aimed at improving effectiveness of immunotherapy in patients with colorectal cancer.
Orlando Health, West Orange Healthcare District Break Ground On New Ocoee Cancer Center
Orlando Health
Leaders with Orlando Health and the West Orange Healthcare District (WOHD) gathered today to break ground on a new cancer center on the campus of Health Central Hospital in Ocoee, Florida.
Barrier Proteins in Tumors are Possible Key to Immunotherapy Success
Johns Hopkins Medicine
By comparing variations in protein expression in tumor samples from a single melanoma patient, researchers from the Johns Hopkins Bloomberg~Kimmel Institute and the Memorial Sloan-Kettering Cancer Center say their findings have the potential to reveal some of the mechanisms underlying response or resistance to immunotherapy drugs. The "proof of concept" findings, published online Feb. 13, 2017, in Clinical Cancer Research, point to distinct variations not in the genetic code of each tumor sample, but in the expression levels of certain proteins encoded by normal genes.
Researchers Define Structure of Key Enzyme Implicated in Cancer, Neurological Disease
Stony Brook University
A Stony Brook University-led team of researchers has determined the structure of a key enzyme involved with cell growth regulation in cancer and neurodegenerative diseases, including Alzheimer's disease.
Harnessing Cancer's Methylation Footprint for More Precise Diagnosis and Prognosis
University of California San Diego Health
In a new study, researchers at University of California San Diego School of Medicine, with colleagues in Xijing Hospital and Sun Yat-sen Cancer Center in China, report that DNA methylation can provide effective markers for at least four major cancers, not only correctly differentiating malignant tissues from normal, but also providing information on prognosis and survival.
NIH Grant Will Fund Research of Cancer Cell Metastasis
University of Delaware
A University of Delaware researcher recently received a grant from the National Institutes of Health to develop a new way to examine how cancer cells metastasize. Metastasis is responsible for 90 percent of cancer-related deaths.
Grant Establishes Proteogenomics Center at U-M
Michigan Medicine - University of Michigan
Researchers at the University of Michigan will lead one of five nationally funded centers dedicated to accelerating research into understanding the molecular basis of cancer and sharing resources with the scientific community.
Three Giants in the Field of Radiation Oncology Named 2017 ASTRO Gold Medalists
American Society for Radiation Oncology (ASTRO)
The American Society for Radiation Oncology (ASTRO) is pleased to announce the 2017 ASTRO Gold Medalists.
Protein Data Takes Significant Step Forward in Medicine
Pacific Northwest National Laboratory
Scientists at the Pacific Northwest National Laboratory and Oregon Health & Science University are part of a nationwide effort to learn more about the role of proteins in cancer biology and to use that information to benefit cancer patients.
Study Shows Biomarkers Can Predict Which ER-Positive Breast Cancer Patients Respond Best to First-Line Therapy
University of Texas M. D. Anderson Cancer Center
Two challenges in treating patients with estrogen-positive breast cancer (ER+) have been an inability to predict who will respond to standard therapies and adverse events leading to therapy discontinuation. A study at The University of Texas MD Anderson Cancer Center revealed new information about how the biomarkers retinoblastoma protein (Rb) and cytoplasmic cyclin E could indicate which patients will respond best to current first-line therapies.
Best in the West: Children's Hospital Los Angeles Named No. 1 Children's Hospital in California and No. 6 in the U.S.
Childrens Hospital Los Angeles
Children's Hospital Los Angeles (CHLA) is the top-ranked pediatric hospital in California again, based on the latest rankings announced by U.S. News & World Report. CHLA was also named to the publication's Honor Roll of Best Children's Hospitals, a designation bestowed on elite pediatric academic medical centers that excel in multiple specialties.
The Children's Hospital of Michigan Ranks Among America's Best in U.S. News & World Report 2017-18 Best Children's Hospitals
Children's Hospital of Michigan
The Children's Hospital of Michigan at the Detroit Medical Center (DMC) is among the best in the country in seven (7) pediatric specialties according to the new 2017-18 Best Children's Hospitals rankings. The Children's Hospital of Michigan is nationally ranked in: Cancer, Gastroenterology & Gastrointestinal Surgery, Nephrology, Neurology & Neurosurgery, Orthopedics, Pulmonology and Urology.
Researchers Chart Pathway to 'Rejuvenating' Immune Cells to Fight Cancers and Infections
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital discovery of the mechanism of T cell exhaustion will lead to treatments to enhance immunotherapies against cancers and such viruses as HIV
Night Shift Work Associated with Diminished Ability to Repair DNA Damage
Fred Hutchinson Cancer Research Center
A Fred Hutchinson Cancer Research Center study, led by epidemiologist Dr. Parveen Bhatti, found that night shift work is associated with reduced ability to repair DNA lesions. Over time, DNA damage that is not repaired will cause mutations that can lead to cancer.
Whatever Your Skin Tone, Spread on the Sunscreen
UT Southwestern Medical Center
No matter what the color of your skin, UT Southwestern cancer experts recommend wearing sunscreen.
Thwarting Metastasis by Breaking Cancer's Legs with Gold Rods
Georgia Institute of Technology
Your cancer has metastasized. No one wants to ever hear that. Now researchers have found a way to virtually halt cell migration, a key component in metastasis, in vitro, in human cells. In past in vivo studies in mice, treated cancer did not appear to recur. No significant side effects were observed.
Immunotherapy Brings New Hope to Patients with Advanced Melanoma
Georgetown Lombardi Comprehensive Cancer Center
Until recently, melanomas that had spread to the brain could only be treated with surgery and radiation therapy. And even with treatment, patients typically lived only a median of four months. However, patients like Kathy Roberts now have alternatives. After having surgery to repair the damage from the tumors in her ankle, her doctors encouraged her to enroll in a clinical trial of immunotherapy for patients with melanoma brain tumors at Georgetown Lombardi Comprehensive Cancer Center, which she did.
Using 'Sticky' Nanoparticles, Researchers Develop New Strategy to Boost Body's Cancer Defenses
University of North Carolina Health Care System
In the journal Nature Nanotechnology, University of North Carolina Lineberger Comprehensive Cancer Center researchers report on strides made in the development of a strategy to improve the immune system's detection of cancer proteins by using "sticky" nanoparticles.
Microscope Can Scan Tumors During Surgery and Examine Cancer Biopsies in 3-D
University of Washington
A new UW microscope could provide real-time results during cancer-removal surgeries, potentially eliminating the 20 to 40 percent of women who have to undergo multiple lumpectomy surgeries because cancerous breast tissue is missed the first time around.
MD Anderson UTHealth Graduate School Receives $10.5 Million Gift
University of Texas M. D. Anderson Cancer Center
Just as he has changed the lives of people suffering from a devastating genetic disease, molecular endocrinologist John J. Kopchick, Ph.D., and his wife, Charlene, of Athens, Ohio, are paving the way for future scientists to do the same with a transformative $10.5 million gift to The University of Texas MD Anderson Cancer Center UTHealth Graduate School of Biomedical Sciences.
Cancer Cells May Streamline Their Genomes in Order to Proliferate More Easily
Stowers Institute for Medical Research
Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. The study, conducted in both human and mouse cells, shows that cancer genomes lose copies of repetitive sequences known as ribosomal DNA. While downsizing might enable these cells to replicate faster, it also seems to render them less able to withstand DNA damage.
Georgia State Hosts First International Triple Negative Breast Cancer Conference
Georgia State University
Georgia State University will host the First International Triple Negative Breast Cancer Conference from Sept. 18 to 20.
Focused Ultrasound Foundation and Cancer Research Institute Partner to Advance Cancer Immunotherapy
Focused Ultrasound Foundation
The Focused Ultrasound Foundation (FUSF) and the Cancer Research Institute (CRI) are establishing a partnership with the goal of advancing the development of new focused ultrasound (FUS) and cancer immunotherapy treatments. Both organizations recognize the intersection of the latest developments in FUS therapy and cancer immunotherapy offers a highly promising opportunity for combination approaches to treat a variety of cancers.
Researchers Create a 'Rosetta Stone' to Decode Immune Recognition
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital and Fred Hutchinson Cancer Research Center have developed an algorithm that predicts T cell recognition of antigens and sets the stage to more effectively harness the immune system
UTHealth's Lenard Lichtenberger Tests Effectiveness of Lipidic Aspirin Formulation Against Cancer
University of Texas Health Science Center at Houston
Scientists at The University of Texas Health Science Center at Houston (UTHealth) are testing the effectiveness of a soy-enriched aspirin formulation designed to fight colorectal cancer with fewer side effects.
New Inhibitor Drug Shows Promise in Relapsed Leukemia
Perelman School of Medicine at the University of Pennsylvania
A new drug shows promise in its ability to target one of the most common and sinister mutations of acute myeloid leukemia (AML), according to researchers at the Perelman School of Medicine at the University of Pennsylvania and Penn's Abramson Cancer Center. The Fms-like tyrosine kinase 3 (FLT3) gene mutation is a known predictor of AML relapse and is associated with short survival. In a first-in-human study, researchers treated relapsed patients with gilteritinib, an FLT3 inhibitor, and found it was a well-tolerated drug that led to frequent and more-sustained-than-expected clinical responses, almost exclusively in patients with this mutation.
UTSW, UT Advanced Computing Center Share Big-Data Tools in Fight Against Cancer, Infectious Diseases
UT Southwestern Medical Center
UT Southwestern scientists who created a powerful analytic weapon in the fight against cancer and infectious diseases are making that tool available for free via a web-based portal.
NCCN Guidelines Compliance for Chest CT Reduces False Positives and Decreases Health Care Spending in Breast Cancer, Study Finds
National Comprehensive Cancer Network(r) (NCCN(r))
As published in JNCCN, a Siteman Cancer Center study uncovered potential to significantly improve NCCN Guidelines-concordant care in patients with early-stage breast cancer.
Surgery and High-Dose SBRT Radiation Can Be Combined to Treat Kidney Cancer, Roswell Park Researchers Show
Roswell Park Cancer Institute
A new study from Roswell Park Cancer Institute reporting the findings of the first clinical trial to evaluate the immune effects of high-dose radiation therapy followed by surgery in patients with advanced kidney cancer may also set the stage for combination treatments with immunotherapy.
Indoor Tanning Still Accessible to Young People--Despite Bans
Yale Cancer Center
Despite legislation prohibiting the use of ultraviolet (UV) indoor tanning facilities by minors, one in every five tanning salons in United States where such bans are in place stated over the phone that they would allow an underage caller to do so.
Tumor Immune Fitness Determines Survival of Lung Cancer Patient
La Jolla Institute for Allergy and Immunology
In recent years, immunotherapy, a new form of cancer therapy that rouses the immune system to attack tumor cells, has captivated the public's imagination. When it works, the results are breathtaking. But more often than not it doesn't, and scientists still don't know why.
Firefly Gene Illuminates Ability of Optimized CRISPR-Cpf1 to Efficiently Edit Human Genome
Scripps Research Institute
Scientists on the Florida campus of The Scripps Research Institute (TSRI) have improved a state-of-the-art gene-editing technology to advance the system's ability to target, cut and paste genes within human and animal cells--and broadening the ways the CRISPR-Cpf1 editing system may be used to study and fight human diseases.
Henry Ford Cancer Institute First in World to Install MRI-Guided Radiation Therapy with MRIdian Linac
Henry Ford Health System
The Henry Ford Cancer Institute is the first in Michigan - and first in the world - to offer patients an advanced radiation therapy that uses an FDA-approved real-time magnetic resonance imaging and linear accelerator delivery for more precise and accurate radiation treatment.
$2.24M Grant Awarded to Rutgers Cancer Institute of New Jersey Researchers
Rutgers Cancer Institute of New Jersey
A $2.24 million competing renewal grant from the National Cancer Institute will support the work of investigators at Rutgers Cancer Institute of New Jersey and Princeton University to learn more about the fuel required for tumor growth. The collaborative research will focus on melanomas and lung cancers caused by mutations in genes known as K-ras and Braf.
Blue-Ribbon Committee Creates Ultrasound Scoring System for Thyroid Nodules to Reduce Unnecessary Biopsies
University of Alabama at Birmingham
National committee creates American College of Radiology ultrasound-based risk stratification system to identify nodules that warrant biopsy or sonographic follow-up, and identify most clinically significant malignancies while reducing the number of biopsies performed on benign nodules.
Fred Hutch Study Suggests NSAIDs Improve Survival for Certain Colorectal Cancer Patients
Fred Hutchinson Cancer Research Center
Among long-term colorectal cancer survivors, use of nonsteroidal anti-inflammatory drugs, or NSAIDs, is associated with about a 25 percent reduction in all-cause mortality, according to new research from Fred Hutchinson Cancer Research Center.
Targeting Immune Cells That Help Tumors Stay Hidden Could Improve Immunotherapy
Health Sciences at the University of Pittsburgh
Researchers have discovered a clue that could unlock the potential of immunotherapy drugs to successfully treat more cancers. The findings, published in Cell, were made in mice and showed that targeting a sub-population of immune cells called regulatory T cells could be an effective approach to treating cancers. The findings also point to what could be an important mechanism by which current immunotherapy drugs work, providing clues to making them more effective.
Research on Crucial Cutting Enzyme Maps Site of DNA Damage in Leukemias and Other Cancers
Children's Hospital of Philadelphia
Researchers studying a DNA-cutting enzyme with a crucial role in regulating the structure of genes have discovered a broad role for its cutting activity in driving abnormal genetic rearrangements called translocations that cause cancer, including leukemias and solid tumors. The findings open possibilities for new clinical approaches.
Inhibitor Drug Improves Overall Survival in Older Radioiodine Resistant Thyroid Cancer Patients
Perelman School of Medicine at the University of Pennsylvania
The drug lenvatinib can significantly improve overall survival rates in a group of thyroid cancer patients whose disease is resistant to standard radioiodine treatment, according to new research from the Perelman School of Medicine at the University of Pennsylvania. The study, published today in the Journal of Clinical Oncology, is the first to show lenvatinib has a definitive impact on overall survival (OS). Researchers found OS improves in patients older than 65 years of age and that the drug is well-tolerated.
CU Cancer Center Chemoprevention Trial Hopes to Stop Lung Cancer Before It Starts
University of Colorado Cancer Center
Ongoing clinical trial by University of Colorado Cancer Center investigators is evaluating the ability of an inhaled form of the pulmonary hypertension drug iloprost to prevent lung cancer.
Talking Breast Cancer for Men's Health Awareness Week
University of California San Diego Health
Protein Network Signals Found to Drive Myeloid Leukemias
Children's Hospital of Philadelphia
Researchers have uncovered how mutations in a protein network drive several high-risk leukemias, offering new prospects for novel therapies. An existing drug might be repurposed to treat these leukemias, and the new understanding of the molecular mechanisms at work may offer clues to other drugs yet to be developed.
A Closer Look at Hair Products and Breast Cancer Risk
Rutgers Cancer Institute of New Jersey
Can use of hair products have an impact on breast cancer risk for women? That is a question explored by investigators from Rutgers Cancer Institute of New Jersey, Rutgers School of Public Health and other colleagues who examined use of hair dyes, hair relaxers and cholesterol-based hair products in African-American and Caucasian women.
UVA Honored as Center of Excellence for Bone Marrow Cancer
University of Virginia Health System
University of Virginia Cancer Center has earned recognition as a national center of excellence for its care of patients with myelodysplastic syndrome (MDS), a cancer of the bone marrow that often leads to leukemia.
Sharpless Appointment as NCI Director Commended by AACI
Association of American Cancer Institutes (AACI)
The Association of American Cancer Institutes applauds the appointment of Norman "Ned" Sharpless, MD, as the next director of the National Cancer Institute. Dr. Sharpless is an AACI board member and director of the University of North Carolina Lineberger Comprehensive Cancer Center, an AACI member.
Researchers Show How a Cancer Gene Protects Genome Organization
University of North Carolina Health Care System
UNC School of Medicine researchers have cracked a long-standing mystery about an important enzyme called Set2 found in virtually all organisms other than bacteria. The basic science finding may have implications for understanding cancer development and how to halt it.
Strategy of Hope: Patients Try Creative Approaches to Fight Brain Cancer
UT Southwestern Medical Center
Dennis Kothmann jots several numbers on a clipboard then pauses, his pen frozen on the last figure. His eyebrows furrow and he quietly mouths a calculation.
Infant Sun Protection: How Parents Can Keep Their Baby Safe
American Academy of Dermatology
Skin cancer is the most common cancer in the United States, and it only takes one blistering sunburn during childhood or adolescence to nearly double a person's chance of developing melanoma, the deadliest form of skin cancer, later in life. This is why it's imperative, say dermatologists from the American Academy of Dermatology, that parents do everything they can to protect their infants from the sun's harmful ultraviolet rays and teach their children healthy sun care habits - starting at an early age.
Study: New Approach to Destroying Deadly Brain Tumors
UT Southwestern Medical Center
A new strategy for treating brain tumors may extend or save the lives of patients diagnosed with one of the deadliest forms of cancer, according to a study from UT Southwestern Medical Center.
Where Cigarette Smoking's Damage is Done . . . Down to Your DNA
University of North Carolina Health Care System
Scientists have known for decades that smoking cigarettes causes DNA damage, which leads to lung cancer. Now, for the first time, UNC School of Medicine scientists created a method for effectively mapping that DNA damage at high resolution across the genome.
Lab on a Chip Could Monitor Health, Germs and Pollutants
Rutgers University
Imagine wearing a device that continuously analyzes your sweat or blood for different types of biomarkers, such as proteins that show you may have breast cancer or lung cancer. Rutgers engineers have invented biosensor technology - known as a lab on a chip - that could be used in hand-held or wearable devices to monitor your health and exposure to dangerous bacteria, viruses and pollutants.
Caregiver, Cancer Survivor and Author: City of Hope Nurse Christine Magnus Moore
City of Hope
As a nurse coordinator in City of Hope's Department of Hematology & Hematopoietic Cell Transplantation, Christine Magnus Moore, R.N., B.S.N., has cared for patients going through the most challenging circumstances one can imagine.
Metastatic Breast Cancer Cells Use Hedgehog to 'Evilize' Docile Neighbors
University of Colorado Cancer Center
University of Colorado Cancer Center study pinpoints promising link in the chain of hedgehog signaling that, when broken, could reduce the metastatic potential of breast cancer.
Study Sheds New Light on Inherited Testicular Cancer Risk
Perelman School of Medicine at the University of Pennsylvania
An analysis of data from five major studies of testicular cancer has identified new genetic locations that could be susceptible to inherited testicular germ cell tumors. The findings, which researchers call a success story for genome mapping, could help doctors understand which men are at the highest risk of developing the disease and signal them to screen those patients.
ASTRO Issues Guideline for Use of Stereotactic Radiation in Early-Stage Lung Cancer
American Society for Radiation Oncology (ASTRO)
The American Society for Radiation Oncology (ASTRO) issued a new clinical guideline for the use of stereotactic body radiation therapy (SBRT) in early-stage lung cancer today.
Flaws in a Tumor's Genetic Mending Kit Drive Treatment Response to Immunotherapy
Johns Hopkins Medicine
In an expanded, three-year clinical trial of 86 patients with colorectal and 11 other kinds of cancer that have so-called 'mismatch repair' genetic defects, scientists at Johns Hopkins Medicine and its Bloomberg~Kimmel Institute for Cancer Immunotherapy have found that half of the patients respond to an immunotherapy drug called pembrolizumab (Keytruda).
Researching Radiosensitizers, a New Class of Drugs That Would Make Tumors More Vulnerable to Radiation Therapy
Southern Research
Two out of three cancer patients are treated with radiation, but the therapy often fails to wipe out the tumor or slow its growth. Southern Research is working to develop a new class of drugs that will help the radiation deliver a more powerful punch to the disease.
Treatment Advances Help Improve Childhood Cancer Survival in New Jersey
Rutgers Cancer Institute of New Jersey
The latest in childhood cancer statistics in New Jersey show significant declines in mortality rates for white, black and Hispanic children from 1979 to 2013. A Rutgers Cancer Institute of New Jersey expert says this improvement in survival can be attributed to treatment advances and participation in clinical trials.
Rutgers Cancer Institute Experts Highlight Testicular Cancer Awareness During Men's Health Month
Rutgers Cancer Institute of New Jersey
While the risk of developing testicular cancer is low, every man should understand some basic facts about this disease. Rutgers Cancer Institute of New Jersey experts share more about the disease, which is the most common malignancy among men ages 15 to 35.
Review of Appendix Cancer Cases Finds Over Diagnosis
University of California San Diego Health
Lesions of the appendix are being over diagnosed as invasive cancer, report University of California San Diego School of Medicine researchers in a paper published June 7 in the journal PLOS ONE.
Mammograms: Are We Overdiagnosing Small Tumors?
Yale Cancer Center
An analysis of breast cancer data revealed that many small breast cancers have an excellent prognosis because they are inherently slow growing, according to Yale Cancer Center experts.