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Study seeks to improve cancer survival for Latinos, Asians and Blacks
UC Davis Comprehensive Cancer Center
UC Davis Comprehensive Cancer Center has received a $6.3 million grant from the National Cancer Institute's (NCI) Center to Reduce Cancer Health Disparities for a 5-year study to tease out why some ethnic and racial minority groups fare worse than whites when they get cancer and to find more precise treatments to improve their chances of survival.
New Nanotherapy Offers Hope in Treating Drug-Resistant Renal Cell Carcinoma
Wayne State University Division of Research
A research team led by Arun Iyer, Ph.D., assistant professor of pharmaceutical sciences in the Eugene Applebaum College of Pharmacy and Health Sciences at Wayne State University, has developed a nanoplatform technology that works in combination with existing chemotherapeutic drugs that may reverse drug-resistance in renal cell carcinoma.
MD Anderson hosts Biden Cancer Community Summit
University of Texas M. D. Anderson Cancer Center
The University of Texas MD Anderson Cancer Center today joined with more than 450 communities and institutions across the country in hosting a Biden Cancer Community Summit, organized under the charge of the Biden Cancer Initiative. The Summit aims to encourage an ongoing dialogue about opportunities to make significant advances in cancer research, prevention, diagnosis and care.
Horwitz Prize Awarded for Work on Hormones
Columbia University Irving Medical Center
Columbia University awards the 2018 Louisa Gross Horwitz Prize to Pierre Chambon, Ronald M. Evans, and Bert W. O'Malley for their research--spanning over 50 years--decoding how steroid hormones and nuclear receptors regulate cell function. This work has transformed our understanding of human physiology and disease.
Surgery, radiation therapy equally effective in treating oropharyngeal cancer
UT Southwestern Medical Center
Adding more evidence to the comparison between radiation therapy and surgery in treating an increasingly diagnosed head and neck cancer, a new study by researchers at UT Southwestern Medical Center found no major long-term differences in the effectiveness of the two therapies.
Chicago Universities to Host Community Forum on City's Cancer Inequities
University of Illinois at Chicago
The Chicago Cancer Health Equity Collaborative (ChicagoCHEC), a National Cancer Institute-funded initiative to reduce cancer disparities in Chicago's low-income neighborhoods, will provide a detailed look at the ongoing work of the ChicagoCHEC partnership, which is led by researchers from the University of Illinois at Chicago, Northeastern Illinois University and Northwestern University, during a community forum on Sept. 21.
Cancer Immunotherapy Might Benefit From Previously Overlooked Immune Players
University of California San Diego Health
Using a bioinformatics approach, University of California San Diego School of Medicine researchers found that CD4+ T cell's binding partner, a molecule called MHC-II, may have even more influence on emerging tumors than MHC-I, the better known partner of CD8+ T cells. The finding, published September 20 in Cell, may help researchers improve cancer immunotherapies and predict which patients will respond best.
2nd Annual Skin Cancer Awareness Walk Returns to Elk Grove Village September 29
Harvard
Skin cancer is the most common cancer in the United States, affecting one in five Americans during their lifetime. To help raise awareness of skin cancer prevention and detection, the American Academy of Dermatology will host Skin Cancer, Take a Hike!(tm) - Chicago on Sat., Sept. 29 in Elk Grove Village. The scenic, four-mile walk at Busse Woods--part of the AAD's SPOT Skin Cancer(tm) campaign to create a world without skin cancer--will benefit skin cancer prevention and detection programs, including free skin cancer screenings, sunscreen dispensers, and permanent shade structures where children learn and play.
Moving Homegrown Ideas into the Clinic
University of Kansas Cancer Center
Physician-scientists at The University of Kansas Cancer center are designing and initiating their own clinical trials.
Novel Biomarker Found in Ovarian Cancer Patients Can Predict Response to Therapy
University of Chicago Medical Center
Researchers have identified an independent prognostic factor, cancer/testis antigen 45, that is associated with extended disease-free survival for women with advanced ovarian cancer. Patients with high levels of CT45 in their tumors lived more than seven times as long as patients who lacked sufficient CT45.
What Can Salad Dressing Tell Us About Cancer? Think Oil and Vinegar
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital scientists have identified another way the process that causes oil to form droplets in water may contribute to solid tumors, such as prostate and breast cancer. The findings appear today in the journal Molecular Cell. Researchers found evidence that mutations in the tumor suppressor gene SPOP contribute to cancer by disrupting a process called liquid-liquid phase separation. Liquid-liquid phase separation is seen often in nature and is the reason why oil and vinegar separate in salad dressing.
Case Western Reserve's Dr. Ahmad Khalil Receives NIH Funding to Develop New Paradigm in Fight against Colorectal Cancer
Case Western Reserve University
Certain genes that code for proteins have long been known to contribute to cancer progression. But in a frame shift, researchers from Case Western Reserve University School of Medicine recently found that non-coding genes also contribute to the development and spreading of the disease, one of the first known examples of researchers doing so. The lead author of the study reporting this finding, Ahmad Khalil, PhD, assistant professor of genetics and genome sciences at Case Western Reserve School of Medicine, has been awarded a five-year, $1.85 million grant from the National Institutes of Health to build on the discovery, with an eventual aim of pinpointing additional targets for cancer-fighting treatments.
What Patients Don't Know (but Should) About Prostate Cancer
University of California, Los Angeles (UCLA), Health Sciences
This Prostate Cancer Awareness Week, urologist shares three things patients are surprised to learn
3 things patients don't know about prostate cancer -- but should
University of California, Los Angeles (UCLA), Health Sciences
Study Uncovers New Hurdle for Developing Immunotherapies
University of Notre Dame
The discovery made by Notre Dame researchers and their collaborators tosses a new wrench into the process of building better molecules to develop immunotherapies
Researchers find adult stem cell characteristics in aggressive cancers from different tissues
University of California, Los Angeles (UCLA), Health Sciences
UCLA researchers have discovered genetic similarities between the adult stem cells responsible for maintaining and repairing epithelial tissues -- which line all of the organs and cavities inside the body -- and the cells that drive aggressive epithelial cancers. Their findings could bring about a better understanding of how aggressive, treatment-resistant cancers develop and progress, and could eventually lead to new drugs for a range of advanced epithelial cancers such as lung, prostate and bladder cancers.
Solving the Gut Inflammation Puzzle
Sanford Burnham Prebys Medical Discovery Institute
Inflammatory bowel disease (IBD), an umbrella term for a number of gut disorders--including ulcerative colitis and Crohn's disease--remains a clinical challenge. Now, researchers from Sanford Burnham Prebys Medical Discovery Institute (SBP), in collaboration with scientists at Technion - Israel Institute of Technology, have identified a protein that drives intestinal inflammation. This finding highlights new opportunities for creating targeted therapeutics. The study published today in Cell Reports.
Thyroid Cancer 101
Rutgers Cancer Institute of New Jersey
While thyroid cancers are common, they may not be as widely understood as other common cancers such as breast or prostate. A Rutgers Cancer Institute of New Jersey expert shares more about the butterfly-shaped gland in the lower neck and how cancer might present there.
Enlarged Genotype-Phenotype Correlation for a Three-Base Pair Deletion in Neurofibromatosis Type 1
University of Alabama at Birmingham
For people with the genetic disorder neurofibromatosis type 1, a three-base pair deletion in the NF1 gene has a mild phenotype, but the mutation causes complications that include non-optic brain tumors, mostly low-grade and asymptomatic, as well as cognitive impairment and/or learning disabilities.
The Cancer Center at BIDMC Opens a Personalized Immunotherapy Cancer Vaccine Facility
Beth Israel Deaconess Medical Center
The Cancer Center at Beth Israel Deaconess Medical Center (BIDMC) today announced the opening of the Randi and Brian Schwartz Family Cancer Immunotherapy and Cell Manipulation Facility. The state-of-the-art laboratory expands BIDMC's research capacity with the ultimate goal of accelerating the delivery of new immunotherapies to patients with cancer.
Do These Things Right Now to Help Prevent Cancer
University of Alabama at Birmingham
UCLA Researchers Develop Mechanism for Characterizing Function of Rare Tumor Cells
University of California, Los Angeles (UCLA), Health Sciences
UCLA researchers have created a quick and effective mechanism to measure how these circulating tumor cells perform functions that drive cancer.
Scientists Reveal Way to Map Vast Unknown Territory of Long Non-coding RNA
University of North Carolina School of Medicine
Scientists from the University of North Carolina School of Medicine have developed a powerful method for exploring the properties of mysterious molecules called long non-coding RNAs (lncRNAs), some of which have big roles in cancer and other serious conditions.
New Benchmarking Tool for Measuring Development and Organization of Integrated Practice Units Published in JNCCN
National Comprehensive Cancer Network(r) (NCCN(r))
Researchers from Netherlands Cancer Institute recommend qualitative and quantitative measurements that can lead to more successfully coordinated cancer care, finds need for better organization around the integration of care, according to article in September 2018 issue of JNCCN-Journal of the Comprehensive Cancer Network.
New Chief of Breast Surgery Named at Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey has named M. Michele Blackwood, MD, FACS, as its new Chief of Breast Surgery. Dr. Blackwood, whose surgical expertise is in complex breast malignancies, is currently the Medical Director and Northern Regional Director of Breast Services for RWJBarnabas Health.
Tackle Kids Cancer Kicks Off Third Year of Eli's Challenge
Hackensack Meridian Health
NY Giants Quarterback to Match $200,000 in Grassroots Fundraising to Support Tackle Kids Cancer
Ovarian Cancer: What You Need to Know
Rutgers Cancer Institute of New Jersey
During this Gynecologic Cancers Awareness Month, a Rutgers Cancer Institute of New Jersey expert shares info on symptoms and treatment of ovarian cancer.
Case Western Reserve's Dr. Lan Zhou Receives $2M NIH Grant to Study Colorectal Cancer Development
Case Western Reserve University
Lan Zhou, MD, PhD, associate professor of pathology at Case Western Reserve University School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer. Her work focuses on the effect of the imbalance of the gut microbiome, the immune response, and genetics in the development of adenocarcinoma (cancer that forms in the lining of the glands) through the serrated pathway.
Cancer Drug and Antidepressants Provide Clues for Treating Fatal Brain-Eating Amoeba Infections
University of California San Diego Health
Researchers at Skaggs School of Pharmacy and Pharmaceutical Sciences at University of California San Diego have now identified three new molecular drug targets in Naegleria fowleri and a number of drugs that are able to inhibit the amoeba's growth in a laboratory dish. Several of these drugs are already approved by the U.S. Food and Drug Administration for other uses, such as antifungal agents, the breast cancer drug tamoxifen and antidepressant Prozac.
Study of Breast Cancer Subtype among New Jersey Women Shows Disparities by Age, Race, and Hispanic-Origin
Rutgers Cancer Institute of New Jersey
When it comes to breast cancer subtype in the Garden State, researchers from Rutgers University and the New Jersey State Cancer Registry find that non-Hispanic black women and women between the ages of 20 to 39 have higher rates of triple-negative disease than females aged 50 to 64 and those of other races and ethnicities.
Rush Clinical Trial Testing Vaccine for Glioblastoma Brain Cancer
Rush University Medical Center
Rush is testing whether a vaccine can help people's own immune system slow the spread of glioblastomas, a deadly form of brain cancer.
U.S. Department of Defense Funds UIC Research on Prostate Cancer
University of Illinois at Chicago
A new three-year grant totaling nearly $1 million from the U.S. Department of Defense will fund University of Illinois at Chicago research on the gene SELENOF and its role in the development of prostate cancer among black men.
Prostate Cancer Care for Older Men Estimated to Cost Medicare $1.2B
University of North Carolina Health Care System
Researchers examined the costs associated with screening for prostate cancer, including treatment, for three years after diagnosis. They estimated that for men diagnosed in each of 2004, 2005, 2006, and 2007, the total cost for treating and screening for each group would be $1.2 billion for three years after diagnosis.
Prostate Cancer PSA Screening: Finding Clarity in Confusion
Rutgers Cancer Institute of New Jersey
With recent changes in recommendations for PSA testing for prostate cancer, confusion may exist for those considering the screening. A Rutgers Cancer Institute of New Jersey expert shares what one needs to know when discussing the topic with his doctor.
ACA Expansion Did Not Improve Access to Complex Surgeries for Low-Income/Minority Patients
Georgetown University Medical Center
Medicaid expansion under the Affordable Care Act does not appear to reduce disparities in use of regionalized surgical care among vulnerable persons.
New Immunotherapy Approach Found in "Superagonist" Interleukin-15 Complex
Roswell Park Comprehensive Cancer Center
A team led by Marc Ernstoff, MD, of Roswell Park Comprehensive Cancer Center found that a drug complex containing IL-15 is both safe and well tolerated in patients with advanced solid tumors.
For women with genetic risk, twice-a-year MRI beats mammograms
University of Chicago Medical Center
Getting magnetic resonance imaging (MRI) scans twice a year instead of one annual mammogram is far more effective at detecting early breast cancers in young women with a high-risk genetic profile than mammograms alone, according to a research team based at the University of Chicago Medicine and the University of Washington, Seattle.
St. Jude Researchers Solve a Central Mystery of a Baffling High-Risk Leukemia
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital investigators have unraveled the origins and identified mutations associated with a perplexing form of acute leukemia. The landmark study appears today as an advance online publication in the journal Nature and lays the foundation for more effective treatment of patients with the high-risk cancer. The research focused on mixed phenotype acute leukemia (MPAL), a subtype of acute leukemia that accounts for about 3 percent of the estimated 3,500 pediatric cases of acute leukemia diagnosed annually in the U.S. Their treatment is complicated because MPAL does not fit cleanly into a single diagnosis, but includes features of both acute lymphoblastic leukemia and acute myeloid leukemia.
New Combination Treatment Targets Pre-Leukemia Stem Cells
University of Colorado Cancer Center
Omacetaxine (to block protein synthesis) with venetoclax (to block oxidative phosphorylation), was highly effective against CD123+ leukemia stem cells.
Findings Could Improve Treatment for Challenging Acute Leukemia in Children
University of North Carolina Health Care System
Researchers from St. Jude Children's Research Hospital and the University of North Carolina Lineberger Comprehensive Cancer Center have made important discoveries that could lead to better treatment for a rare blood cancer in children that has features of both acute myeloid leukemia and acute lymphoblastic leukemia.
#UAB Prostate cancer experts available to discuss symptoms & treatment for Prostate Health Awareness Month.
University of Alabama at Birmingham
Toward an "Ultra-Personalized" Therapy for Melanoma
Weizmann Institute of Science
Prof. Yardena Samuels of the Weizmann Institute, working with a global team, has developed a way to target a patient's unique melanoma cells. The immunotherapy creates, in effect, a new drug for each person.
Shedding Light on 100-Year-Old Cancer Mystery
Sanford Burnham Prebys Medical Discovery Institute
Using genetic and pharmacological means, scientists at Sanford Burnham Prebys Medical Discovery Institute (SBP) were surprised to find that blocking LDHA had only a limited impact on melanoma cells, since they were able to redirect energy production. Their results identify an alternative growth pathway driven by a molecule called ATF4, revealing new potential targets for drug development. The study was published today in EMBO Journal.
SMHS Nets $20.3M Cancer Research Grant
University of North Dakota
A $20.3-million, five-year grant to the University of North Dakota could help counter high cancer rates in North and South Dakota.
Collaboration with Almoosa Specialist Hospital to bring UChicago Medicine's clinical expertise to patients in Saudi Arabia
University of Chicago Medical Center
The University of Chicago Medicine and Almoosa Specialist Hospital, a private hospital in the Al-Ahsa region of Saudi Arabia offering comprehensive medical care, have signed a collaboration agreement.
$37 Million CPRIT Support Includes Funds for Pediatric Cancer Database
UT Southwestern Medical Center
The Cancer Prevention and Research Institute of Texas (CPRIT) has awarded more than $37 million to UT Southwestern for cancer research and prevention.
Loyola Medicine Pediatric Cancer Patient Drafted by Chicago Cubs
Loyola University Health System
Teen baseball players overcomes cancer to see his dream of being drafted come true.
New Guidelines Provide Vital Information for Women Diagnosed with the Most Common Type of Gynecologic Cancer
National Comprehensive Cancer Network(r) (NCCN(r))
National Comprehensive Cancer Network publishes NCCN Guidelines for Patients: Uterine Cancer during Gynecologic Cancer Awareness Month to explain treatment options and raises awareness of endometrial cancer, the most common type of gynecologic cancer.
MD Anderson immunotherapy expert Sharma wins Coley Award
University of Texas M. D. Anderson Cancer Center
Padmanee Sharma, M.D., Ph.D., professor of Genitourinary Medical Oncology and Immunology at The University of Texas MD Anderson Cancer Center, has been recognized for her innovative work understanding factors that enhance and hinder cancer immunotherapy. Sharma will receive the William B. Coley Award for Distinguished Research in Tumor Immunology, awarded annually by the Cancer Research Institute (CRI), at an annual meeting co-sponsored by CRI in New York Sept. 30 to Oct. 3.
Study Links BAP1 Protein to Tumor Suppression in Kidney, Eye, Bile Duct and Mesothelioma Cancers
University of Texas M. D. Anderson Cancer Center
Researchers at The University of Texas MD Anderson Cancer Center have shown how BRCA-associated protein 1 (BAP1) serves as a tumor suppressor gene in kidney, eye, bile duct, mesothelioma and other cancers by regulating a form of cell death called ferroptosis, opening up a potential new area of therapy research. Findings from the study, led by Boyi Gan, Ph.D., associate professor, Department of Experimental Radiation Oncology, were published in the Sept. 10 online issue of Nature Cell Biology.
Optimizing Technologies for Discovering Cancer Cell Mutations
Penn State College of Medicine
A team of researchers has developed a new framework that can combine three existing methods of finding mutations -- or structural variants -- in the DNA of cancer cells into a single, more complete picture.
U-M cancer researcher awarded $6.5M Outstanding Investigator Award to explore precision oncology
Michigan Medicine - University of Michigan
A new grant to University of Michigan Rogel Cancer Center member Arul Chinnaiyan, M.D., Ph.D., will provide long-term support to increase understanding of genetic markers to leverage targeted treatments for cancer.
Changes in the Architecture Around Cancer Cells Can Fuel Their Spread
University of California, Los Angeles (UCLA), Health Sciences
UCLA researchers have found that an often overlooked component of a cell, the extracellular matrix, can influence how much sugar the cell consumes and its migratory behavior.
Ovarian Cancer: Quick Steps to Widespread Disease
University of Chicago Medical Center
Ovarian cancer cells that interact with cancer-associated fibroblasts can mobilize glycogen as an energy source, leading to proliferation, invasion and metastasis. Blocking glycogen mobilization in cancer cells might reduce tumor spread.
Hackensack Meridian Health John Theurer Cancer Center to Host 10th Annual Celebrating Life & Liberty
Hackensack Meridian Health
Hackensack Meridian Health John Theurer Cancer Center at Hackensack University Medical Center, one of the nation's top 50 hospitals for cancer, will host its tenth annual Celebrating Life and Liberty event at MetLife Stadium, featuring special performances. The event celebrates survivorship and generates inspiration and support to those in the cancer community who are still in treatment or recovery. This free celebration on Friday, September 14 from 5 p.m. to 9:30 p.m, is open to all Hackensack Meridian Health patients, survivors and families, caregivers and dedicated health care staff who have played important roles in their journeys.
Renowned Lung Cancer Expert Joins Perlmutter Cancer Center
NYU Langone Health
Nationally renowned clinician and researcher Vamsidhar "Vamsi" Velcheti, MD, recently joined Perlmutter Cancer Center at NYU Langone Health as Director of Thoracic Medical Oncology, enhancing the center's efforts to improve clinical care, increase translational and clinical research, and promote interdisciplinary collaborations in lung cancer.
Roswell Park Team Identifies Possible Cause of Resistance to Prostate Cancer Treatment
Roswell Park Comprehensive Cancer Center
A Roswell Park-led research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target. Their findings were published in the journal Nature Communications.
Scientists Identify Weak Point in Deadly Eye Melanoma
Washington University in St. Louis
A natural plant compound exploits a newly identified Achilles' heel in a cancer of the eye, uveal melanoma. In human cancer cells growing in the lab, the compound shuts down the overactive signaling that drives uveal melanoma cell growth, according to researchers at Washington University School of Medicine in St. Louis.
AACI/CCAF Annual Meeting Considers Shape of Things to Come in Cancer Research
Association of American Cancer Institutes (AACI)
The 2018 joint annual meeting of the Association of American Cancer Institutes and the Cancer Center Administrators Forum, September 30 - October 2, will highlight perspectives on the future of cancer research and care, and the latest on CAR T-cell therapy, Big Data management, and international partnerships.
Modular Fluidic System Developed to Supply Radioisotope Used in Targeted Alpha Therapy
Department of Energy, Office of Science
Laboratory automation applied to complex radiochemical isolation of astatine-211 from cyclotron-bombarded targets.
Hormone Therapy Can Make Prostate Cancer Worse, Study Finds
Cedars-Sinai
Scientists at Cedars-Sinai have discovered how prostate cancer can sometimes withstand and outwit a standard hormone therapy, causing the cancer to spread. Their findings also point to a simple blood test that may help doctors predict when this type of hormone therapy resistance will occur.
Clinical Trial Shows Best Outcomes to Date for Older Hodgkin Lymphoma Patients
Rutgers Cancer Institute of New Jersey
Recently published results of a phase 2 clinical trial have shown the best outcomes to date for newly diagnosed older Hodgkin lymphoma patients treated with brentuximab vedotin given before and after doxorubicin, vinblastine and dacarbazine (AVD) chemotherapy, which is the standard of care.
Focused Delivery for Brain Cancers
Washington University in St. Louis
Hong Chen, assistant professor of biomedical engineering in the school of Engineering & Applied Science, and assistant professor of radiation oncology at the School of Medicine, reached across disciplines to develop a more focused drug delivery system that can target tumors lodged in the brainstem.
Andrews Patel Hematology/Oncology joins Penn State Health
Penn State Health Milton S. Hershey Medical Center
A practice known for providing high-level oncology and hematology services to people in central Pennsylvania for more than 30 years is now part of Penn State Health Medical Group.
Overcoming Resistance
Beth Israel Deaconess Medical Center
In a recent paper published in the journal Clinical Cancer Research (CCR), Carmelo Nucera, MD, PhD, primary investigator in the thyroid cancer research program in the Division of Experimental Pathology in BIDMC's Department of Pathology, and colleagues investigated the role of pericytes as part of the tumor microenvironment in the subset of papillary thyroid cancers modulated by a mutation of the BRAF cancer-promoting gene.
Breast Cancer Researcher Svasti Haricharan Joins SBP Faculty
Sanford Burnham Prebys Medical Discovery Institute
Breast cancer researcher Svasti Haricharan joins SBP faculty
National Cancer Institute funds research on computer-generated patient care summaries
University of Illinois at Chicago
The University of Illinois at Chicago has received nearly $1.5 million in funding from the National Cancer Institute, one of the National Institutes of Health, to expand research and development of computer-generated patient care summaries as a tool for reducing hospital readmission rates.
New Test Uncovers Metabolic Vulnerabilities in Kidney Cancer
UT Southwestern Medical Center
A team of investigators used intraoperative infusions of labeled glucose in patients about to have surgery to remove the kidney cancer to assess how the tumors use glucose.
Stem cells show promise as drug delivery tool for childhood brain cancer
University of North Carolina Health Care System
UNC Lineberger Comprehensive Cancer Center researchers showed they could shrink tumors in laboratory models of medulloblastoma. The study, published in PLOS ONE, is a necessary step toward developing clinical trials that would see if the approach works for children.
Success of Colorectal Cancer Intervention Program recognized by National Cancer Institute
Texas Tech University Health Sciences Center El Paso
A Texas Tech University Health Sciences Center El Paso initiative that is increasing the number of screenings for colorectal cancer across West Texas has caught the eye of the National Cancer Institute.
Experts available: September is Thyroid Cancer Awareness Month
University of Alabama at Birmingham
Dermatologist Develops App to Help Medical Students Spot Skin Cancer
West Virginia University
Michael Kolodney, who chairs West Virginia University's Department of Dermatology, has developed a smartphone app to cultivate that intuition in medical students sooner. An initial study suggests that the app, called Skinder, may improve how accurately medical students diagnose melanomas.
Cancer Patients Guaranteed Oncofertility Treatment Coverage Under New Illinois Law
Northwestern University
Illinois cancer patients no longer have to choose between costly life-saving treatments and preserving their ability to one day have their own biological children, thanks to a fertility preservation bill signed Aug. 27 by Gov. Bruce Rauner at Northwestern Medicine Prentice Women's Hospital.
Roswell Park Approach to Assessing Kidney Tumors May Spare Some Patients Surgery
Roswell Park Comprehensive Cancer Center
A research team from Roswell Park Comprehensive Cancer Center has discovered a way to use computed tomography (CT) imaging to assess kidney tumors that test positive for the biomarker CD117 and accurately determine -- before surgery -- whether the tumor is benign or malignant.
Mapping Out Cancer's Movements
American Institute of Physics (AIP)
Cancer researchers struggle to identify tumor cells that are interspersed within nonmalignant tissues because tumor cells exploit the tissue environment and monopolize available resources to continue growing. Researchers attribute cancer cell's ability to use cell signaling and metabolic pathways that override normal cell growth restrictions to complicated chemical exchanges between tissue and tumor cells. A new approach shows promise to begin analyzing cell-to-cell interactions in this complex environment. The researchers discuss their work in Biointerphases.
Combination Approach Shows Promise for Beating Advanced Melanoma
University of California, Los Angeles (UCLA), Health Sciences
A UCLA-led study has found that a treatment that uses a bacteria-like agent in combination with an immunotherapy drug could help some people with advanced melanoma, an aggressive form of skin cancer, live longer.
Researchers to Test Novel Drug Combination Against Toughest Breast Cancers
University of California San Diego Health
Researchers at University of California San Diego School of Medicine have launched a phase Ib clinical trial to assess the safety and tolerability of cirmtuzumab, in combination with standard chemotherapy, to treat metastatic or locally advanced breast cancer that cannot be surgically removed.
CAR T Cell Therapy Receives Approval for Use Across European Union
Perelman School of Medicine at the University of Pennsylvania
The European Commission (EC) has approved a personalized cellular therapy developed at the University of Pennsylvania's Abramson Cancer Center, making it the first chimeric antigen receptor (CAR) T cell therapy permitted for use in the European Union in two distinct indications.
Palliative Care Physician Available to Talk About End of Life Care in Relation to John McCain's Decision to Stop Cancer Treatments
University of Alabama at Birmingham
Advanced Microscope Technology Reveals Novel Side to Cell Signaling Complex
UT Southwestern Medical Center
In a study published today in Science, UT Southwestern and Rockefeller University researchers used advanced microscopes to determine at atomic resolution the structure of a molecular complex implicated in birth defects and several cancers.
3-D Cell Environment Crucial for Divvying Up Chromosomes - Find Could Help Explain Cancer Hallmark
Howard Hughes Medical Institute (HHMI)
Epithelial cells grown on a plastic dish are worse at segregating their chromosomes than epithelial cells growing in mice, a new study shows. The results may help explain why chromosomes go awry in cancer.
Integrated Analysis Finds Vulnerabilities to Target in a High-Risk Pediatric Tumor
St. Jude Children's Research Hospital
Research from the St. Jude Children's Research Hospital--Washington University Pediatric Cancer Genome Project has revealed new vulnerabilities and leads for treatment of rhabdomyosarcoma
$500K Grant Aids Exploration of Genetic Changes in Pancreatic Cancer for New Treatment Targets
Rutgers Cancer Institute of New Jersey
A $500,000 grant from the Pancreatic Cancer Action Network will help a Rutgers Cancer Institute of New Jersey physician-scientist explore a biological event associated with a signaling pathway known as Netrin-1 that enables cancer cells to live.
Scientists Close in on Mystery Surrounding Dangerous Blood Syndromes
Cincinnati Children's Hospital Medical Center
Scientists may be on the road to solving the mystery of a group of mostly incurable blood diseases called myelodysplastic syndromes (MDS), which cause people to have immature, malfunctioning bone marrow cells that fuel a diverse set of health problems and can lead to leukemia. Researchers report in the journal Cancer Discovery identifying a gene that in laboratory experiments fuels the biological processes that cause the different types of MDS that physicians see in patients.
Combination Immunotherapy Shrinks Melanoma Brain Metastases
University of Texas M. D. Anderson Cancer Center
Combination immunotherapy shrank melanoma that has spread to the brain in more than half of the patients in a clinical trial reported in the New England Journal of Medicine led by an investigator at The University of Texas MD Anderson Cancer Center.
Study Reveals How Enzyme Detects Ultraviolet Light Damage
University of California San Diego Health
In a paper published this week in the journal PNAS, researchers at University of California San Diego School of Medicine, with colleagues in Spain and Finland, describe for the first time how one type of RNA polymerase gets stalled by DNA lesions caused by exposure to ultraviolet (UV) light.
Christopher Kane, MD, Appointed CEO of UC San Diego Health Physicians
University of California San Diego Health
Christopher Kane, MD, has been appointed dean of clinical affairs for UC San Diego School of Medicine and CEO of UC San Diego Health Physicians, effective July 15. In these dual roles, Kane will collaborate with UC San Diego leadership to ensure that UC San Diego Health Physicians achieve the highest standards of service, access, quality, safety, and patient satisfaction and are integrated to support the unique and growing needs of an expanding academic health system and its growing regional network of providers.
Cervical Cancer Expert Available to Comment on New USPSTF Guidelines
University of Chicago Medical Center
From Mindfulness to Medical Education: Penn Radiation Oncology Explores the Potential of VR
Perelman School of Medicine at the University of Pennsylvania
Penn's Radiation Oncology department has recently added a VR mindfulness experience to its waiting room in the Roberts Proton Therapy Center.
St. Jude Achieves Consecutive Highest Rating From National Cancer Institute During Cancer Center Renewal Grant
St. Jude Children's Research Hospital
For the second time in a row, the National Cancer Institute has awarded St. Jude Children's Research Hospital the highest possible rank of "exceptional" and the best numerical score in the hospital's history during the renewal of the hospital's $36 million Comprehensive Cancer Center grant. St. Jude is the first and only NCI-designated Comprehensive Cancer Center that is devoted solely to children.
Nancy E. Davidson Joins Board of Directors for Ludwig Institute for Cancer Research
Ludwig Cancer Research
Ludwig Cancer Research is pleased to welcome Nancy E. Davidson to the Ludwig Institute Board of Directors. Nancy Davidson, a physician-scientist with extensive expertise in breast cancer research, is a leader in the cancer research community.
Sequencing Genomes of Nigerian Women Could Help Prevent Many Lethal Breast Cancers
University of Chicago Medical Center
A study that enrolled more than 2,000 Nigerian women found that disparities in breast cancer mortality disproportionately impact women of African ancestry. Nigerian women with mutations in breast cancer genes have higher risks than women in the U.S. with mutations in the same genes. Inherited breast cancer plays a bigger role in Nigeria.
Five Facts About Ovarian Cancer Everyone Should Know
University of California, Los Angeles (UCLA), Health Sciences
Although ovarian cancer is often considered a relatively rare cancer - accounting for only about 3 percent of all cancers in women - it causes more deaths than any other cancer of the female reproductive system. In September, also known as Ovarian Cancer Awareness Month, share these 5 facts with your friends and loved ones.
Colorectal #Cancer Screening Recommendations Should Remain for Now Says Expert @UCSDHealth
University of California San Diego Health
$500K Pledge from Hugs for Brady Foundation Supports Dedicated Laboratory Space for Pediatric Cancer Research at Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey
The Hugs for Brady Foundation has announced a $500,000 pledge to Rutgers Cancer Institute of New Jersey to support a dedicated laboratory space for pediatric cancer research.
Research Informs New National Cervical Cancer Screening Recommendation
UC Davis Comprehensive Cancer Center
A comprehensive analysis of eight clinical trials and four cohort studies on cervical cancer screening by researchers from UC Davis and Kaiser Permanente Northwest has found that while Pap smears are still highly effective for detecting pre-cancerous cells and cancer, testing for the virus that causes these cancers also is an excellent screening tool.
Annual Pap Test a 'Thing of the Past?'
Florida Atlantic University
The U.S. Preventive Services Task Force has updated its 2012 recommendations for cervical cancer screening with one important addition. This is the first time they are recommending a method of cervical cancer screening that does not include the Pap test - the gold-standard screening test for more than 75 years. A leading OB/GYN physician provides an important review of these new guidelines, which preserve the greatest range of choices for practitioners and patients.
Compound Discovered at Sanford Burnham Prebys Advances Into Phase 1 Trial for Pancreatic Cancer
Sanford Burnham Prebys Medical Discovery Institute
A compound discovered at Sanford Burnham Prebys Medical Discovery Institute (SBP) has advanced into a Phase 1 trial for metastatic pancreatic cancer. Called CEND-1 (scientifically known as iRGD), the compound was exclusively licensed in 2015 to a private company, DrugCendR Inc. The drug candidate was discovered in the laboratory of Erkki Ruoslahti, M.D., Ph.D., distinguished professor at SBP and founder, president and CEO of DrugCendR.
UPMC Pathology Expert Available to Discuss Importance of Pap Smears in Addition to HPV Testing for Cervical Cancer.
Health Sciences at the University of Pittsburgh
Konica Minolta Again Joins the Fight against Childhood Cancer Supporting the Children's Cancer Institute at the Joseph M. Sanzari Children's Hospital
Hackensack Meridian Health
Konica Minolta Business Solutions U.S.A. Inc. (Konica Minolta) announced they will again support Tackle Kids Cancer, a philanthropic initiative on behalf of the Children's Cancer Institute at the Joseph M. Sanzari Children's Hospital at Hackensack Meridian Health Hackensack University Medical Center.