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Increase your Awareness of Head and Neck Cancers
Rutgers Cancer Institute of New Jersey
Accounting for approximately four percent of all cancers nationwide according to the National Cancer Institute, head and neck cancer is the term used to describe a number of different malignant tumors that develop in or around the throat, larynx, nose, sinuses and mouth. Even though these cancers are not as prevalent as others, everyone should be aware of risk factors and symptoms.

MD Anderson researchers highlight advances in clinical studies at the AACR Annual Meeting 2021
University of Texas M. D. Anderson Cancer Center
FDA-approved selpercatinib shows clinical benefits for RET fusion-positive cancers beyond lung and thyroid cancers (Abstract CT011); Combining dabrafenib and trametinib to treat BRAF V600E-mutant high-grade (HGG) and low-grade glioma (LGG) shows significant antitumor activity; Therapeutics Discovery researchers identify key biomarker for metabolic inhibitor

Researchers identify surface protein as a new osteosarcoma therapeutic target for antibody-drug conjugates
University of Texas M. D. Anderson Cancer Center
Novel approach paves the way for vast expansion in the number of drugs targeting osteosarcoma

Huntsman Cancer Institute Research Shows Melanoma Incidence and Mortality Higher in Utah Compared to Rest of U.S.
Huntsman Cancer Institute at the University of Utah
A letter published today by Huntsman Cancer Institute (HCI) at the University of Utah (U of U) in the New England Journal of Medicine reports that melanoma mortality among Utahns outpaced that of the rest of the United States during the period from 1975 to 2013. Melanoma death rates have been decreasing in recent years both in Utah and the United States, a trend likely attributable to new, more effective treatments, like immunotherapy. However, melanoma remains the deadliest type of skin cancer, and the incidence of melanoma diagnoses in Utahns is higher than in any other state.

John Theurer Cancer Center Investigators Celebrate New Personalized Cell Therapy to Give Patients with Advanced Multiple Myeloma Hope
Hackensack Meridian Health
The U.S. Food and Drug Administration recently approved a new CAR-T therapy called idecabtagene vicleucel (ide-cel), or Abecma. It's the first personalized cell therapy to treat patients with multiple myeloma no longer responsive to all standard previous types of therapy. This new therapy was assessed in the pioneering phase II clinical KarMMA trial, at Hackensack Meridian John Theurer Cancer Center at Hackensack Meridian Hackensack University Medical Center.

Mutant KRAS and p53 cooperate to drive pancreatic cancer metastasis
University of Texas M. D. Anderson Cancer Center
Preclinical research identifies CREB1 as new therapeutic target downstream of frequently mutated genes

Men with Low Health Literacy Less Likely to Choose Active Surveillance for Prostate Cancer After Tumor Profiling
University of Illinois at Chicago
Tumor gene profiling is a tool that can help patients with a cancer diagnosis make informed decisions about treatment. In predominantly white populations, among men with early stage, favorable-risk prostate cancer, these tools have been shown to increase patient acceptance of active surveillance -- a common, evidence-based approach to monitor the tumor before a more aggressive treatment, like surgery or radiation.
An amyloid link between Parkinson's disease and melanoma
American Chemical Society (ACS)
For nearly 50 years, doctors have recognized that Parkinson's disease patients have an increased risk of melanoma. Now, scientists report a link between the two diseases in the form of protein aggregates known as amyloids. They will present their results at ACS Spring 2021.

Cervical Cancer Testing Tech Could Replace Pap Smears, Save Lives
American Institute of Physics (AIP)
Emerging technologies can screen for cervical cancer better than Pap smears and, if widely used, could save lives in areas where access to health care may be limited. In Biophysics Reviews, scientists at Massachusetts General Hospital write advances in nanotechnology and computer learning are among the technologies helping develop HPV screening that take the guesswork out of the precancer tests. That could mean better screening in places that lack highly trained doctors and advanced laboratories.

Surgery is a viable treatment for pancreatic cancer patients especially after chemotherapy
American College of Surgeons (ACS)
Patients with stage II pancreatic cancer who are treated with chemotherapy followed by resection (an operation that removes the cancerous part of the organ, structure or tissue) live nearly twice as long as patients who receive only chemotherapy.

'Leap forward' in risk management of rectal cancer
Washington University in St. Louis
Rectal cancer, along with colon cancer, is the third-most common type of cancer in the United States, and treatment and surgery greatly affect the quality of life of patients. A multi-disciplinary team at Washington University in St. Louis has developed and tested an innovative imaging technique that is able to differentiate between rectal tissues with residual cancers and those without tumors after chemotherapy and radiation, which could one day help to avoid unnecessary surgeries in some patients who have achieved complete tumor destruction after chemoradiation.

A clue to how some fast-growing tumors hide in plain sight
La Jolla Institute for Immunology
Viruses churn out genetic material in parts of the cell where it's not supposed to be. Cancer cells do too. A new study shows that a tumor-suppressor enzyme called DAPK3 is an essential component of a multi-protein system that senses misplaced genetic material in tumor cells, and slows tumor growth by activating the fierce-sounding STING pathway.

Planning for Life after Cancer
Rutgers Cancer Institute of New Jersey
Oncology Social Worker from Rutgers Cancer Institute of New Jersey provides insight on the survivorship experience and navigating life after cancer.

UCLA team receives $6 million from NIH to explore new pancreatic cancer therapies
University of California, Los Angeles (UCLA), Health Sciences
A team of researchers from the UCLA Jonsson Comprehensive Cancer Center has been awarded two research grants totaling $6 million from the National Institutes of Health to identify new ways to treat pancreatic cancer.

Preparing for exascale: Aurora supercomputer to help scientists visualize the spread of cancer
Argonne National Laboratory
In advance of Argonne's Aurora exascale supercomputer, Duke University assistant professor Amanda Randles is leading a new study to analyze cancer metastasis using HARVEY, a code that simulates blood vessels within the human body.

Starting Smoking Cessation in Hospitalized Patients Would Reduce Many Premature Deaths
Florida Atlantic University
Each year in the U.S., about 30 million hospitalizations occur in individuals 18 and older. Of these, more than 7 million are current cigarette smokers whose average hospital stay is several days. Researchers say that starting smoking cessation therapy during hospitalization and maintaining high adherence post-discharge can markedly improve permanent quit rates in these patients with minimal to no side effects. Cessation therapy also should include long-term counseling and at least 90 days of a prescription drug, specifically, varenicline.

Sylvester Researchers Reveal New Link Between Obesity, Chemerin and Kidney Cancer
University of Miami Health System, Miller School of Medicine
Research published in the AACR journal Cancer Discovery found that a protein named chemerin is present in higher quantities in the blood of obese individuals and plays an essential role in controlling fat metabolism in kidney cancer cells.

Exploiting cancer cells to aid in their own destruction
University of Chicago
Researchers at the Pritzker School of Molecular Engineering at the University of Chicago have developed a new therapeutic vaccine that uses a patient's own tumor cells to train their immune system to find and kill cancer.

New Director of Neuro-Oncology Named to New Jersey's Only NCI-designated Comprehensive Cancer Center
Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey welcomes Michael E. Salacz as director of its Neuro-Oncology Program.

New sequencing approach finds triple-negative breast cancers continue accumulating genetic changes during tumor growth
University of Texas M. D. Anderson Cancer Center
A new DNA sequencing approach developed by MD Anderson researchers overcomes technical challenges with earlier techniques to give deeper insights into breast cancer evolution.

Fighting Cancer with DNA Origami
Department of Energy, Office of Science
Scientists have devised a new way to build nanomaterials that can maintain their structural integrity and functionality in ways relevant to drug delivery. The team developed a class of molecular coatings compatible with biological environments. They used these coating to stabilize wireframed DNA origami cages that can carry an anticancer drug with a slower release of the medicine over time than possible with noncoated counterparts.

Richard M. Horowitz Appointed Chair of The Wistar Institute's Board of Trustees
Wistar Institute
Wistar is pleased to announce the appointment of Richard M. Horowitz as chair of its Board of Trustees.

Cecelia Calhoun Named Director of the Adolescent-Young Adult Sickle Cell Program at Yale Cancer Center and Smilow Cancer Hospital
Yale Cancer Center
Cecelia Calhoun, MD, MSPH, MBA, has been appointed Assistant Professor of Medicine (Hematology) and Assistant Professor of Pediatrics (Hematology/Oncology) at Yale Cancer Center and Smilow Cancer Hospital

Multiple Myeloma Explained
Rutgers Cancer Institute of New Jersey
Expert from Rutgers Cancer Institute of New Jersey shares information on symptoms, treatment and more to highlight multiple myeloma awareness month.

Weizmann Scientists Find That Bacteria May Aid Anti-Cancer Immune Response
Weizmann Institute of Science
The Weizmann Institute's Prof. Yardena Samuels, Prof. Eran Segal, and Dr. Ravid Straussman, with partners at MD Anderson Cancer Center, the NCI, and elsewhere, have discovered that the bacteria living inside cancer cells can be harnessed to provoke an immune reaction against the tumor. The work could also help explain findings showing that the microbiome affects the success of immunotherapy.

New Barrett's esophagus monitoring method could aid in easier and more precise prognoses
Case Western Reserve University
A new technique for sampling and testing cells from Barrett's esophagus (BE) patients could result in earlier and easier identification of patients whose disease has progressed toward cancer or whose disease is at high risk of progressing toward cancer.

Majority of Cancer Patients with COVID-19 Have Similar Immune Response to People Without Cancer
Albert Einstein College of Medicine
Most people with cancer who are infected by the novel coronavirus produce antibodies at a rate comparable to the rest of the population--but their ability to do so depends on their type of cancer and the treatments they've received, according to a new study by researchers at Montefiore Health System and Albert Einstein College of Medicine. The findings, published online today in Nature Cancer, may lead to better care for cancer patients, who face a heightened risk of dying from COVID-19, and suggests that cancer patients should respond well to COVID-19 vaccines.

Hormone Drugs May Disarm COVID-19 Spike Protein and Stop Disease Progression
Perelman School of Medicine at the University of Pennsylvania
Hormone drugs that reduce androgen levels may help disarm the coronavirus spike protein used to infect cells and stop the progression of severe COVID-19 disease, suggests a new preclinical study from researchers in the Abramson Cancer Center at the University of Pennsylvania and published online in Cell Press's iScience.

Exploring PD-L1 Expression in Malignant Peritoneal Mesothelioma
Rutgers Cancer Institute of New Jersey
In a recent study from Rutgers Cancer Institute of New Jersey, researchers tested whether or not mesothelioma cancer cells express high amounts of PD-L1, a protein that is abundantly present on some types of cancer cells. The PD-L1 protein is an inhibitory molecule that binds to the PD-1 receptor on T-cells, which are cells known to have the ability to recognize and destroy cancer cells in the body. Results of the work are being shared as a poster presentation at the Society of Surgical Oncology 2021 International Conference on Surgical Cancer Care virtual meeting.

More is better, at least when it comes to case volume for complex gastrointestinal cancer surgery
American College of Surgeons (ACS)
A new study reinforces the principle that "practice makes perfect" when it comes to complex GI cancer operations.

Starving tumors by blocking glutamine uptake
Sanford Burnham Prebys Medical Discovery Institute
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake of glutamine, a key food source for many tumors, and slows the growth of melanoma.

CU Cancer Researcher Wins Two Awards to Study Drug-Resistant Cancer Cells
University of Colorado Cancer Center
Sabrina L. Spencer, PhD, is a CU Boulder researcher and CU Cancer Center member. Spencer recently won the Damon Runyon-Rachleff Innovation Award and the Emerging Leader Award. She will use the grants to continue her research on drug resistance in cancer cells.

Reversing Cancer's Gluttony
University of California San Diego Health
Researchers at UC San Diego School of Medicine and Moores Cancer Center describe how pancreatic cancer cells use an alternative method to find necessary nutrients, defying current therapies, to help them grow and spread.

Expert Available to Discuss Expanded USPSTF Lung Cancer Screening Guidelines
The Society of Thoracic Surgeons

Physician and Patient Groups Call On CMS to Update Medicare Lung Cancer Screening Coverage
The Society of Thoracic Surgeons
STS--in collaboration with the GO2 Foundation for Lung Cancer and the American College of Radiology--formally requested that CMS update its coverage policies to reflect the new USPSTF lung cancer screening guidelines.

ATRT molecular groups: looking at the biology from the clinic
St. Jude Children's Research Hospital
Scientists at St. Jude Children's Research Hospital are learning more about what the molecular groups of a rare pediatric brain tumor mean for clinical care.

Exploring Racial and Ethnic Disparities in Colorectal Cancer Screening among Patients with Diabetes
Rutgers Cancer Institute of New Jersey
Researcher at Rutgers Cancer Institute of New Jersey and Rutgers Robert Wood Johnson Medical School has received $400,000 in awards to help identify and overcome multi-level factors such as patient, health professionals and clinic systems affecting optimal use of colorectal cancer preventative screening options for patients with elevated medical and social risks throughout the United States.

Researchers Identify a New, Vital Player in Graft-Versus-Host Disease and Organ Transplant Rejection
Michigan Medicine - University of Michigan
An RNA molecule, cataloged in scientific databases simply as Linc00402, helps activate immune defenders known as T cells in response to the presence of foreign human cells. Findings suggests inhibiting the RNA therapeutically might improve outcomes for transplant recipients.

AACI Cancer Disparities Podcast Launches with Inaugural Guest Dr. Norman E. Sharpless
Association of American Cancer Institutes (AACI)
The Association of American Cancer Institutes (AACI) has launched a new podcast, "Accelerating Equity: Cancer Care for All," hosted by AACI President Dr. Karen E. Knudsen. Her first guest is Dr. Norman E. Sharpless, director of the National Cancer Institute.

Research News Tip Sheet: Story Ideas from Johns Hopkins Medicine
Johns Hopkins Medicine
During the COVID-19 pandemic, Johns Hopkins Medicine Media Relations is focused on disseminating current, accurate and useful information to the public via the media. As part of that effort, we are distributing our "COVID-19 Tip Sheet: Story Ideas from Johns Hopkins" every other Wednesday.

Growing Together: New Social Work Manager Joins Comprehensive Team at Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey
Rutgers Cancer Institute of New Jersey welcomes Joan Hogan, MSW, LCSW, OSW-C, as manager of social work. Learn more about her and her plans for expanding the social work program.

GI OnDEMAND Announces Partnership with Ambry Genetics for Genetic Testing and Counseling Services
American College of Gastroenterology (ACG)
GI OnDEMAND(r), gastroenterology's leading multidisciplinary virtual integrated care platform today announced a partnership with Ambry Genetics(r), a leading clinical genetic testing company, to integrate online genetic counseling and testing services into gastroenterology practices nationwide. This partnership addresses a critical clinical need for identifying hereditary GI cancer syndromes to help guide potentially life-altering health care decisions. GI OnDEMAND, a joint venture between the American College of Gastroenterology and Gastro Girl, Inc., will now offer the CARE (Comprehensive, Assessment, Risk, and Education) Program(tm) from Ambry Genetics.

Scientists shrink pancreatic tumors by starving their cellular "neighbors"
Sanford Burnham Prebys Medical Discovery Institute
Scientists at Sanford Burnham Prebys Medical Discovery Institute demonstrated for the first time that blocking "cell drinking," or macropinocytosis, in the thick tissue surrounding a pancreatic tumor slowed tumor growth--providing more evidence that macropinocytosis is a driver of pancreatic cancer growth and is an important therapeutic target. The study was published in Cancer Discovery, a journal of the American Association for Cancer Research.

NUS researchers harness AI to identify cancer cells by their acidity
National University of Singapore
Healthy and cancer cells can look similar under a microscope. One way of differentiating them is by examining the level of acidity, or pH level, inside the cells. Tapping on this distinguishing characteristic, a research team from the National University of Singapore (NUS) has developed a technique that uses artificial intelligence (AI) to determine whether a single cell is healthy or cancerous by analysing its pH. Each cancer test can be completed in under 35 minutes, and single cells can be classified with an accuracy rate of more than 95 per cent.

Doctors should address reduced sense of taste and smell in cancer patients, Tulane study says
Tulane University
The study is a joint project of the Tulane Department of Psychology and the Tulane Cancer Center.

Machine Learning Can Identify Cancerous Cells by Their Acidity
American Institute of Physics (AIP)
Researchers have developed a method, described in APL Bioengineering, that uses machine learning to determine whether a single cell is cancerous by detecting its pH. Their approach can discriminate cells originating from normal tissues from cells originating from cancerous tissues, as well as among different types of cancer, while keeping the cells alive. The method relies on treating the cells with bromothymol blue, a pH-sensitive dye that changes color depending on acidity.

Exploring Amino Acids Signaling as Intervention for Diabetes and Pancreatic Cancers
Rutgers Cancer Institute of New Jersey
Researchers from Rutgers Cancer Institute of New Jersey previously identified a small protein called Rab1A that regulates amino acid signaling. In a recent study, researchers explored the physiological role of Rab1A in mammals using mice though a technique in which one of an organism's genes is made inoperative, known as genetic knockout.

Researchers identify potential therapeutic target against malignant brain tumors
University of Alabama at Birmingham
Researchers at UAB have identified a potential new pathway to treating radiation-resistant glioblastoma, one of the most aggressive forms of brain cancer. The findings indicate that an adhesive cell surface protein known as N-cad may be key in overcoming glioblastoma's resistance to radiation therapy.
When Regular Radiation was too Risky, Rahway Woman, Receives Innovative Alternative Treatment
Hackensack Meridian Health
Seven years ago, Nikki Burleigh of Rahway, New Jersey, was diagnosed with lung cancer and underwent conventional radiation therapy and a lobectomy to remove the affected part of her lung. Her treatment was successful, and she received regular checkups with her pulmonologist and oncologist for several years. But in December 2019, a routine CT scan revealed that Nikki's lung cancer returned.

Cancer Immunotherapy Approach Targets Common Genetic Alteration
Johns Hopkins Medicine
Researchers developed a prototype for a new cancer immunotherapy that uses engineered T cells to target a genetic alteration common among all cancers. The approach, which stimulates an immune response against cells that are missing one gene copy, called loss of heterozygosity (LOH), was developed by researchers at the Ludwig Center, Lustgarten Laboratory and the Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center.

Study finds high tumor mutation burden predicts immunotherapy response in some, but not all, cancers
University of Texas M. D. Anderson Cancer Center
A high rate of genetic mutations within a tumor, known as high tumor mutation burden, was only useful for predicting immunotherapy responses in a subset of cancer types, suggesting that this may not reliably be used as a universal biomarker.

Cancer Center Network Sites Can Improve Patient Satisfaction and Outcomes, AACI Survey Finds
Association of American Cancer Institutes (AACI)
In a survey of the status of care across cancer center networks, some of which reach deep into rural areas, the Association of American Cancer Institutes (AACI) has found that many opportunities exist for such networks to increase patient satisfaction and outcomes and decrease treatment delays and risks.

Cancer physician-scientist offers expertise on new lung cancer CT screening recommendations
Indiana University

RNA Editing Protein ADAR1 Protects Telomeres and Supports Proliferation in Cancer Cells
Wistar Institute
Wistar scientists identified a new function of ADAR1, a protein responsible for RNA editing, discovering that the ADAR1p110 isoform regulates genome stability at chromosome ends and is required for continued proliferation of cancer cells.

Board-Certified Dermatologists: Studies Show Sun-Protective Behaviors Vary by Where You Live, Race, and Sex
American Academy of Dermatology
NYU Langone Brings Top Talent to Advance Cancer Care in Brooklyn
NYU Langone Hospital - Brooklyn
To help develop the latest treatment methods and expand cancer care service, Thomas Daniels, MD, has been appointed service chief of the Department of Radiation Oncology at Perlmutter Cancer Center-Sunset Park in Brooklyn.

Promising role for whole genome sequencing in guiding blood cancer treatment
Washington University in St. Louis
A new study from Washington University School of Medicine in St. Louis shows that whole genome sequencing is at least as accurate and often better than conventional genetic tests that help determine the treatment for a patient's blood cancer. Genome sequencing technology continuously is decreasing in cost and recently reached a level similar to that of conventional testing.

Stopping Mutant KRAS Could Lead to Enhanced Therapies for Pancreatic Cancer
Stony Brook University
A collaborative study by Stony Brook University scientists, published in Nature Communications, takes an initial step toward better understanding how KRAS drives immune evasion and demonstrates a lowering of the KRAS activity resulting in a more favorable immune environment to fight cancer.
Loss of Y chromosome, RNA tied to radiation resistance in male lung-cancer patients
West Virginia University
The science behind the COVID-19 vaccine has the potential to do more than prevent cases of COVID-19 itself. In the coming years, it could also help doctors treat stubborn forms of cancer.

New Los Alamos generator system delivers large radiation doses directly to cancer cells
Los Alamos National Laboratory
Improved options for cancer treatment are on the way, thanks to a new system developed at Los Alamos National Laboratory for producing alpha-emitting medical radioisotopes intended to target and overpower diseased tissue while sparing the healthy tissue around it.

Story Tips from Johns Hopkins Experts on COVID-19
Johns Hopkins Medicine
Since its opening in January 2016, the Johns Hopkins Capacity Command Center has helped the Johns Hopkins Health System manage hospital operations -- notably the flow of patients. So when the COVID-19 pandemic and the first people with the illness came to the hospital, the capacity command center was ready to manage the influx of patients.

Sloan Kettering Institute Researchers Named 2021 Kravis Women in Science Endeavor Fellowship Grant Recipients
Memorial Sloan Kettering Cancer Center
Memorial Sloan Kettering Cancer Center (MSK) announced that Sloan Kettering Institute (SKI) researchers Regina Bou Puerto and Mijin Kim, PhD, have been named 2021 Marie-Josee Kravis Women in Science Endeavor (Kravis WiSE) fellowship grant recipients. The Kravis WiSE initiative, created in 2020, provides sustained funding for scientific trainees as well as mentoring and significant professional development for women pursuing careers in biomedical research at MSK. The Kravis WiSE Symposium is held every year during Women's History Month in March. This event hosts scientific leaders from MSK and other institutions.

Andrew Ewald Named Director of Johns Hopkins Medicine's Department of Cell Biology
Johns Hopkins Medicine
Cancer researcher Andrew Ewald, Ph.D., has been appointed director of the Department of Cell Biology at the Johns Hopkins University School of Medicine. He will take over the position from Peter Devreotes, Ph.D., who will remain on the faculty at Johns Hopkins. Ewald joined the medical school faculty in 2008 as an assistant professor in the Department of Cell Biology. His research focuses on how basic cellular processes, such as cell-to-cell connections and migration, contribute to cancer progression. He is known for his discoveries of the mechanisms by which breast cancer cells leave the primary tumor and spread through the body during metastasis.

UVA Health's Dr. Cynthia Yoshida Honored Nationally for Increasing Colorectal Cancer Screenings
University of Virginia Health System
UVA Health's Cynthia M. Yoshida, MD, is one of six winners of a national award recognizing healthcare providers and institutions for their work to increase colorectal cancer screening rates.

Therapy Sneaks into Hard Layer of Pancreatic Cancer Tumor and Destroys it From Within
University of California San Diego Health
Researchers at University of California San Diego School of Medicine and Moores Cancer Center demonstrated that a new tumor-penetrating therapy could enhance the effects of chemotherapy, reduce the spread of pancreatic cancer and increase survival in animal models.

JNCCN: New Evidence on Need to Address Muscle Health among Patients with Cancer
National Comprehensive Cancer Network(r) (NCCN(r))
Results of new study in JNCCN from Mass General Hospital Cancer Center, Harvard Medical School, and Dana-Farber Cancer Institute underscore the need for the development and testing of nutrition and fitness interventions, as muscle quality significantly correlates with symptom burden, healthcare utilization, and survival.

Research offers insights on how night shift work increases cancer risk
Washington State University
New clues as to why night shift workers are at increased risk of developing certain types of cancer are presented in a new study conducted at Washington State University Health Sciences Spokane.

New AI approach enables research collaboration while protecting patient privacy
University of California, Los Angeles (UCLA), Health Sciences
Dr. Corey Arnold and his graduate student, Karthik Sarma, explain how federated learning can enable more powerful AI models while enhancing the protection of patient data

New CAR T-Cell Therapy Extends Remission In Heavily Relapsed Multiple Myeloma Patients
UT Southwestern Medical Center
DALLAS - March 8, 2021 - A new type of CAR T-cell therapy more than triples the expected length of remission for multiple myeloma patients who have relapsed several times, according to an international clinical trial with UT Southwestern as the lead enrolling site.

Kidney Cancer: 5 Things You Need to Know
Rutgers Cancer Institute of New Jersey
Nearly 74,000 people will be diagnosed with kidney cancer in the United States this year according to the American Cancer Society.

Yale Study Shows Combined Liver-Cytokine Humanization Rescues Circulating Red Blood Cells for Testing of Novel Therapeutics
Yale Cancer Center
In a new study by the Yale Department of Immunobiology and Yale Cancer Center, researchers report combined liver and growth factor humanization enhances human red blood cell production and survival in circulation the immunodeficient murine host.

Incredible Story of Survival After HPV Related Cancer Diagnosis on HPV Awareness Day 2021
Hackensack Meridian Health

Collagen plays protective role during pancreatic cancer development
University of Texas M. D. Anderson Cancer Center
Contrary to long-held beliefs, new research finds that collagen in the tumor microenvironment may not promote cancer development but plays a protective role in controlling pancreatic cancer growth. The new findings could have important therapeutic implications.

St. Jude launches program to boost HPV cancer prevention across the globe
St. Jude Children's Research Hospital
St. Jude is dedicating staff and resources to focus on the prevention of human papillomavirus (HPV)-related cancers around the world through HPV vaccine awareness programming.

Oncology Social Workers: Helping Heal the Wounds We Can't See
Rutgers Cancer Institute of New Jersey
Social workers in the oncology field play a critical role in cancer care, helping patients, their families and caregivers successfully navigate many of the challenges they face, and this important care has continued through the COVID-19 pandemic.

A World without Cervical Cancer: Preventive Medicine publishes special issue to further global efforts to eliminate deadly disease
Moffitt Cancer Center
Cervical cancer is a serious global health threat which kills more than 300,000 women every year. Recognizing this urgent public health issue, the editorial team of Preventive Medicine is publishing a special issue titled "From Science to Action to Impact: Eliminating Cervical Cancer," which outlines the required courses of action to eliminate cervical cancer. Dr. Anna Giuliano and Dr. Linda Niccolai, two giants in the field of cervical cancer prevention research, served as guest editors for the issue.

The Medical Minute: Colonoscopy comes calling earlier under new screening guidelines
Penn State Health
Evolving evidence shows screening tests should actually start at age 45 for people at average risk for colorectal cancer. Two Penn State Health doctors discuss new guidelines.

CRISPR Clinical Trials: A 2021 Update
Innovative Genomics Institute
A comprehensive review of the current CRISPR clinical trials landscape, covering progress on blood disorders, cancers, eye disease, chronic infection, rare protein-folding disease, and future prospects.

Roswell Park Researchers Identify New Biomarker of Response to Checkpoint Inhibitors
Roswell Park Comprehensive Cancer Center
A team of Roswell Park Comprehensive Cancer Center researchers has identified a new biomarker that could predict response to immune checkpoint inhibitors (ICI) shortly after patients with non-small cell lung cancer (NSCLC) initiate therapy. This discovery, published today in the journal Nature Communications, is not only an important step forward in lung cancer treatment, but also has implications for other malignancies, according to lead author Fumito Ito, MD, PhD, FACS.

March is the Month to Get to the Bottom of Colorectal Cancer
Cedars-Sinai
Discussions about digestion and elimination can be embarrassing, so many people, young and old, tend to avoid them. But ignoring the topic and skipping colorectal cancer screening can lead to deadly results, experts say.

Utah Researchers Illuminate Potential Precursors of Blood Cancers
Huntsman Cancer Institute at the University of Utah
Utah researchers report significant new insights into the development of blood cancers. Comparing DNA data in people with and without blood disorders, the researchers discovered genetic mutations in about 2% of the presumably healthy participants that were identical to those frequently observed in the cancer patients. These findings provide new clues about mutations that may initiate cancer development and those that may help cancer progress.
Leading Expert in Women's Cancers Appointed Director of Gynecologic Oncology at Perlmutter Cancer Center
NYU Langone Health
Nationally renowned surgeon and women's cancers expert Leslie R. Boyd, MD, has been named director of the Division of Gynecologic Oncology

Exploring Mutational Signatures Associated with Exposure to Carcinogenic Microplastic Compounds
Rutgers Cancer Institute of New Jersey
According to the World Health Organization (WHO), plastic products and their chemical derivatives present in the environment present public health concerns, including elevated risk of cancer. Researchers from Rutgers Cancer Institute of New Jersey explored to what extent common components in microplastic pollutants cause DNA damage in human cells.

100,000th Cancer Survivor Receives Survivorship Plan Through Penn Medicine's OncoLink
Perelman School of Medicine at the University of Pennsylvania
Penn Medicine's OncoLink -- the first cancer information website on the internet -- has hit a new milestone: 100,000 cancer survivors from around the world have now received a personalized survivorship care plan through the website to guide them through life after cancer.

Memorial Cancer Institute Together with FAU Research Partnership Earn 'Cancer Center of Excellence' Designation
Florida Atlantic University
A research partnership formed just last year by Memorial Healthcare System and Florida Atlantic University is already being recognized for quality care, results, and advances in research, and that's great news for patients fighting cancer in South Florida. The alliance between Memorial's Cancer Institute and FAU (MCIFAU) has been recognized by the state's Department of Health as a "Florida Cancer Center of Excellence." It becomes just the fifth in the state, out of more than 80 competitors, to earn the designation.

Supercomputers Illustrate the Mechanical Process of Cancer Growth
University of California San Diego
According to the World Health Organization, one in six worldwide deaths are attributed to cancer, but not due to initial malignant tumors. They were caused by the spread of cancer cells to surrounding tissues, which consist largely of collagen. That was the focus of a recent study by Stanford University and Purdue University researchers.

Colorectal Cancer: Common Questions Answered
Rutgers Cancer Institute of New Jersey
Knowledge can be your fist line of defense against colorectal cancer. Rutgers Cancer Institute expert addresses what you need to know about colorectal cancer screening, treatment and more during colorectal cancer awareness month.

Yale Researchers Identify Tumor Reactive Immune-Cells to help fight against Advanced Melanoma
Yale Cancer Center
According to a new study led by Yale Cancer Center and Department of Neurology researchers, a simple blood draw may be the first step in helping to discover tumor reactive immune or T cells to treat advanced melanoma, a deadly form of skin cancer. The findings were published today in the Journal of Experimental Medicine.

Colonoscopy: Yes, This is a Test
Hackensack Meridian Health
Colorectal cancer is the second leading cause of cancer death for both men and women, according to the Centers for Disease Control and Prevention (CDC), even though 90 percent of people who are diagnosed through early testing can be cured.

Case Comprehensive Cancer Center researchers to lead Northeast Ohio initiative to increase prostate cancer screening in African American men
Case Western Reserve University
African American men in Cuyahoga County have a 60% increased risk of being diagnosed with prostate cancer and an 80% increased risk of dying from prostate cancer compared to white men, according to data from the Case Comprehensive Cancer Center. With a new $2.75 million, three-year grant from the Bristol Myers Squibb Foundation, researchers at the Case Comprehensive Cancer Center at Case Western Reserve University will collaborate with a team of community partners in a different approach to fight this health disparity.

Parents of Children with Cancer Have Additional Worries During COVID
Duke Health
The COVID-19 pandemic has heaped additional financial strains, childcare complications and other problems on already-burdened caregivers of children diagnosed with cancer, according to a study from researchers at Duke Health and other institutions.

Cancer discovery up for year's biggest biomedical advance in a different kind of March Madness
University of Virginia Health System
The public can vote in STAT Madness, which is like the scientific version of the NCAA basketball tournament.

Significant New Findings about Breast and Ovarian Cancer in Patients from the Caribbean
University of Miami Health System, Miller School of Medicine
In this study, among Caribbean-born individuals with breast and ovarian cancer, 1 in 7 had hereditary breast and ovarian cancer. The proportion of hereditary breast and ovarian cancer varied by island and each island had a distinctive set of variants.

Putting the Spotlight on Colorectal Cancer Risk and Prevention during Colorectal Cancer Awareness Month
University of Chicago Medical Center

Socioeconomic status plays a major role in cognitive outcomes
St. Jude Children's Research Hospital
Childhood cancer and its treatment can result in cognitive struggles. St. Jude scientists are studying the risk factors.

New NCCN Guidelines for Histiocytosis Clarify Best Practices for Recently-Defined Cancers
National Comprehensive Cancer Network(r) (NCCN(r))
NCCN announces the publication of new NCCN Guidelines(r) for Histiocytic Neoplasms, rare disorders characterized by a buildup of white blood cells leading to tissue damage. The three most-common forms are Langerhans cell histiocytosis (LCH), Erdheim-Chester disease (ECD), and Rosai-Dorfman disease.

Congratulations to Dover, NJ, Man Who Remains Cancer-Free after 2013 Robot-Assisted Throat Cancer Surgery
Hackensack Meridian Health
Hawley to oversee Rogel Cancer Center education, training programs
Michigan Medicine - University of Michigan
The University of Michigan Rogel Cancer Center has named Sarah Hawley, Ph.D., M.P.H., associate director for training, education and career development. She will lead the center's efforts to coordinate and enhance robust resources that support faculty, trainees and students interested in cancer research.

Chenevert Family Brain Tumor Center Launched at Yale
Yale Cancer Center
Yale School of Medicine announces a gift to establish the Chenevert Family Brain Tumor Center at Yale Cancer Center. The Chenevert Family Brain Tumor Center will be a leading center in Neuro-Oncology research worldwide, bringing ground-breaking solutions and hope to patients with brain tumors.

New Model Predicts Cancer Drug Efficacy Across and Within Cancer Types
Michigan Medicine - University of Michigan
As large multi-cancer datasets become more important for predicting who may benefit from cancer drugs, a new model better accounts for potentially overlooked variation.