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Pessoas com uma superabundância de glóbulos brancos clonados, ou linfócitos, que prejudicam o seu sistema imunológico — uma condição chamada linfocitose monoclonal de células B (LMB) — podem apresentar um risco elevado de desenvolver várias complicações de saúde, incluindo o melanoma, uma forma de câncer de pele.

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Researchers at UC Davis and UCLA have created models for four sarcoma subtypes using stem cells. The findings may lead to new therapies.

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Personas con una sobreabundancia de glóbulos blancos clonados, o linfocitos, que dañan su sistema inmunológico, una afección llamada linfocitosis monoclonal de células B (LMB), pueden tener un riesgo elevado de desarrollar diversas complicaciones de salud, incluido el melanoma, una forma de cáncer de piel.

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Heather High, a second-grade teacher and mother of four from Bella Vista, Arkansas, and her 14-year-old son Elijah have something in common – a love of gifted and talented education. High has completed a Master of Education degree in Gifted, Creative, and Talented Education while Elijah has been battling brain cancer.

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The National Cancer Institute-designated Montefiore Einstein Comprehensive Cancer Center (MECCC) has announced the new Marilyn and Stanley M. Katz Institute for Immunotherapy for Cancer and Inflammatory Disorders. Xingxing Zang, Ph.D., an international leader in developing novel immunotherapies, has been named its inaugural director.

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During the European Society for Medical Oncology (ESMO) Congress, Saby George, MD, FACP, of Roswell Park Comprehensive Cancer Center presented findings on a novel two-agent treatment that more than doubled progression-free survival compared with single-agent treatment.

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Treatment with a combination of haloperidol and lorazepam reduced symptoms of agitated delirium, a common end-of-life condition for patients with advanced cancers, compared with haloperidol alone, according to a new study led by researchers at The University of Texas MD Anderson Cancer Center.

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During every moment of any living organism’s life, enzymes are at work. These crucial proteins support life through most biological processes, including metabolism, movement, respiration, and digestion. “Enzymes’ effects in cells are part of normal physiology,” said Kathleen Mulvaney, assistant professor at Virginia Tech’s Fralin Biomedical Research Institute.

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A drug that delivers chemotherapy directly to tumors has shown impressive activity against some of the hardest-to-reach cancer cells: those that have spread to the brain in patients with advanced HER2-positive breast cancer. Research led by Dana-Farber Cancer Institute.

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In an international multicenter randomized phase 3 clinical trial led by Dana-Farber Cancer Institute, researchers tested the addition of the immune checkpoint inhibitor (ICI) nivolumab to treatment with tivozanib for patients with advanced clear cell renal cell carcinoma.

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The antibody-drug conjugate (ADC) puxitatug samrotecan (AZD8205) demonstrated a manageable safety profile consistent with similar ADCs and initial efficacy in heavily pretreated patients with advanced or metastatic solid tumors, according to interim data shared today at the 2024 European Society for Medical Oncology (ESMO) Congress by researchers from The University of Texas MD Anderson Cancer Center.

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Explore how Huntsman Cancer Institute's 25-year legacy of excellence is reaching new heights and advancing cancer treatments of the future beyond the standard of care today.

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An interdisciplinary team of researchers from the University of Illinois has discovered a potential new treatment option for drug-resistant breast cancer. Their findings, published in Breast Cancer Research and Treatment, demonstrates the role of activators of ferroptosis in overcoming acquired resistance to FOXM1 inhibitors.

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A study by UdeM professor Claude Perreault's team at IRIC proposes three potential functions for so-called parasite DNA sequences in T cell development.

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The Cedars-Sinai Board of Governors Regenerative Medicine Institute is creating a resource laboratory to help advance stem cell-based technologies throughout Cedars-Sinai and across California.

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Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients. This discovery has fueled new strategies that incorporate antibodies and gene editing to improve the outcome of this breakthrough treatment for patients.