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New Contrast Agent Combination Could Usher in a New Era of Vascular Systems Biology
American Physiological Society (APS)
A new contrast agent combination for imaging tumor samples enhances data extraction and thus benefits modeling of tumor processes. The discovery will be presented today at the American Physiological Society (APS) Interface of Mathematical Models and Experimental Biology conference.
Cancer Protocols: A New Approach to Predicting Treatment Outcomes
Weizmann Institute of Science
Research by the Weizmann Institute of Science's Prof. Yardena Samuels shows that heterogeneity in melanoma tumors prevents effective immune responses
The Genetics of Cancer
University of Delaware
A research team has identified a new circular RNA (ribonucleic acid) that increases tumor activity in soft tissue and connective tissue tumors. The discovery may help improve how cancer is identified and treated.
Pediatric Hematology / Oncology Nurse Taking on Life after Cancer
Children's of Alabama
September 2019 marks two years since Courtney Alvis was hired as a pediatric hematology/oncology nurse at Children's of Alabama, where in 2010 she was diagnosed with acute T-cell leukemia at age 16.
Can scientists predict which cancer markers are likely to trigger an immune response?
University of North Carolina Health Care System
In a study published in the journal Cancer Immunology Research, University of North Carolina Lineberger Comprehensive Cancer Center researchers reported on the discovery of a method for predicting whether abnormal proteins produced by cancer cells could trigger an immune response.
Failed Cancer Drug Looks Promising For Scleroderma And Other Fibrotic Conditions
Johns Hopkins Medicine
Sixteen years ago, a research group at Mayo Medical School published results showing that a protein called TRAIL can kill cells that cause liver fibrosis but no one seemed to follow up on these findings. Now, researchers at Johns Hopkins Medicine have improved on this protein and shown that it selectively kills cells that cause the hardening of skin associated with scleroderma, effectively reversing the condition in mice genetically engineered to mimic the disease. A report on these results was published earlier this year in Nature Communications.
$1.25 Million Gift to Endow Chair at Jersey Shore University Medical Center
Hackensack Meridian Health
The Hackensack Meridian Health Jersey Shore University Medical Center Foundation is pleased to announce a gift of $1.25 million from Charles Adell to create The Charles & Jackie Adell Endowed Chair in Surgical Oncology at Jersey Shore University Medical Center.
Two Studies Show Promise, Safety of Proton Therapy in the Brain in Children with Cancer
Perelman School of Medicine at the University of Pennsylvania
From improving outcomes in children with brain cancer to lowering the risk of damage to the brainstem in children with central nervous system tumors, a pair of new studies published today add to the growing body of research showing the potential benefits of proton therapy.
New Federal Guidelines for BRCA Testing: Should You Be Screened?
Cedars-Sinai
More women than ever are being encouraged to undergo screening for BRCA gene mutations, based on newly announced U.S. Preventive Services Task Force recommendations. The task force recommends that:
Meet the molecule that helps stressed cells decide between life and death
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital scientists have identified a molecule that plays a pivotal role in determining the fate of cells under stress, much like a Roman emperor deciding the fate of gladiators in the coliseum.
Existing drug could treat aggressive brain cancer
University of Georgia
A research team from the University of Georgia's Regenerative Bioscience Center has found that a compound molecule used for drug delivery of insulin could be used to treat glioblastoma, an aggressive, usually fatal form of brain cancer.
Breast Cancer Cells 'Stick Together' to Spread Through The Body During Metastasis
Johns Hopkins Medicine
Researchers at the Johns Hopkins Kimmel Cancer Center discovered that a cell adhesion protein, E-cadherin, allows breast cancer cells to survive as they travel through the body and form new tumors, a process termed metastasis.
NUS invention makes biopsies less invasive and more informative
National University of Singapore
A team of researchers from the National University of Singapore (NUS) has developed a novel technology that could sensitively and accurately detect and classify cancer cells, as well as determine the disease aggressiveness from the least invasive biopsies. With this new technology called STAMP (Sequence-Topology Assembly for Multiplexed Profiling), comprehensive disease information can be obtained faster
UCLA oncologist Dennis Slamon wins 2019 Lasker Award for clinical medical research
University of California, Los Angeles (UCLA), Health Sciences
Physician-scientist Dr. Dennis Slamon, has been awarded the 2019 Lasker-DeBakey Clinical Medical Research Award for the groundbreaking development of breast cancer drug Herceptin (trastuzumab), a life-saving therapy for women with HER2-positive breast cancer.
KU Cancer Center receives grant to expand clinical trials in rural Kansas
University of Kansas Cancer Center
The University of Kansas Cancer Center and Midwest Cancer Alliance have been awarded a grant to expand the reach of cancer clinical trials to Kansas' rural communities.
Unmarried Patients Less Likely to Survive Cancer as Bias Drives Treatments
University of Delaware
Unmarried patients with cancer are less likely to get potentially life-saving surgery or radiotherapy than their married counterparts, raising the concern that medical providers may be relying on stereotypes that discount sources of social support other than a current spouse. That's the conclusion reached by the University of Delaware's Joan DelFattore, a professor emerita who combined her personal experience as an unmarried patient with her skills as a researcher to publish a peer-reviewed article in the latest issue of The New England Journal of Medicine.
CAP Opens Comment Period on Diffuse Glioma Guideline; Participate to Improve Patient Outcomes
College of American Pathologists (CAP)
CAP opens comment periods on Diffuse Glioma Guideline
Three Cancer Center Directors Elected to AACI Board
Association of American Cancer Institutes (AACI)
Drs. Carlos L. Arteaga, S. Gail Eckhardt, and Caryn Lerman have been elected to serve on the Board of Directors of the Association of American Cancer Institutes (AACI).
'Together We Answer Cancer' campaign raises awareness, funds for cancer research, patients and families
University of Chicago Medical Center
The University of Chicago Medicine is partnering with the Anthony Rizzo Family Foundation and key media outlets in a multifaceted cause-marketing campaign to support the American Cancer Society.
Tweets Indicate Nicotine Dependence, Withdrawal Symptoms of JUUL Users
Health Sciences at the University of Pittsburgh
One out of every five tweets mentioning JUUL indentified for a new analysis also references addiction-related themes.
Rush Earns ASCO QOPI Certification for High-Quality Cancer Care
Rush University Medical Center
Rush University Medical Center has received a three-year certification from the American Society of Clinical Oncology's Quality Oncology Practice Initiative (QOPI) by demonstrating that the Cancer Center's processes surpass national benchmarks for providing high-quality care.
Swallowable Device to Detect Pre-cancerous Barrett's Esophagus Receives FDA 510(k) Clearance
Case Western Reserve University
Investigators at Case Western Reserve University School of Medicine, the Case Comprehensive Cancer Center and University Hospitals Cleveland Medical Center developed the test for early detection of Barrett's esophagus that offers promise for preventing deaths from esophageal adenocarcinoma.
NYU Oral Cancer Center Awarded $2.5 Million NIH Grant to Study Cancer Pain
New York University
Researchers at New York University (NYU) Oral Cancer Center were awarded a $2.5 million grant from the National Cancer Institute to study the role of artemin in oral cancer pain and growth.
2019 Gynecologic Cancer Survivorship Conference: Thriving Through Education and Connection
Johns Hopkins Medicine
A premier educational event sponsored by the Johns Hopkins Kelly Gynecologic Oncology Service and the Division of Gynecologic Oncology at Sibley Memorial Hospital, this one-day conference gathers more than 25 experts to provide cancer survivors and their caregivers
Researchers Characterize Lung Inflammation Associated With Some Cancer Immnunotherapy
Johns Hopkins Medicine
Immune checkpoint inhibitors are a type of therapy that uses the immune system to fight cancer. They have been hailed as game changing, garnering a Nobel Prize last year and quickly becoming the standard of care for many tumor types such as melanoma and certain lung and head and neck cancers.
Native American cancer survivors found health and hope through exercise and community
Northern Arizona University
In one of the first studies of its kind, the Restoring Balance program, a collaboration between Northern Arizona University and the University of Arizona Cancer Center, offered cancer patients, survivors and their caregivers a physical activity regimen and sessions with Native American trainers to learn how to combine western and Native medicine. The results so far? It's working.
MD Anderson study confirms protein as potential cause of most common type of pancreatic cancer
University of Texas M. D. Anderson Cancer Center
An oncogene, UPS21, has been confirmed as a frequently amplified gene in pancreatic ductal adenocarcinoma, the most common and often lethal form of pancreatic cancer. The discovery could lead to new treatment options.
Henry Ford Cancer Institute First-in-Michigan, Second-in-World to Complete Laser Spinal Ablation
Henry Ford Health System
Henry Ford Cancer Institute is the first-in-Michigan and second-in-the-world to complete an innovative cancer treatment known as Spinal Laser Interstitial Thermal Therapy (SLITT), which destroys cancer cells that are adjacent to the spine without the need for open surgery.
Aesthetics of skin cancer therapy may vary by treatment type
Penn State College of Medicine
While there are several effective options for treating non-melanoma skin cancers, some may result in better cosmetic appearance after treatment, according to researchers.
Researchers Move Beyond Sequencing and Create a 3D Genome
St. Jude Children's Research Hospital
St. Jude Children's Research Hospital scientists have taken whole genome sequencing to the next level by creating a 3D map of the genome to better understand development and disease
FAK Protein Linked to Chemotherapy Resistance in Ovarian Cancer
University of California San Diego Health
A new University of California San Diego School of Medicine study links changes in the gene for the protein focal adhesion kinase, or FAK, to ovarian cancer's ability to survive chemotherapy.
Fellowship focuses on providing future psychologists specialized training in cancer care
University of Kansas Cancer Center
Clinical health psychology fellowship emphasizes psychological care for people with cancer.
Team Aims to Close Rural-Urban Cancer Survival Gap
University of Kansas Cancer Center
Researchers from The University of Kansas Cancer Center has received a five-year, $2.25 million grant from the National Cancer Institute to study why there are survival rate disparities in rural parts of Kansas, and how to improve them.
Medical Imaging Rates Continue to Rise Despite Push to Reduce Their Use
UC Davis Health
Despite a broad campaign among physician groups to reduce the amount of imaging in medicine, the rates of use of CT, MRI and other scans have continued to increase in both the U.S. and Ontario, Canada, according to a new study of more than 135 million imaging exams.
Drug Designed to Treat Metastatic Pancreatic Cancer May Help Extend Life
Stony Brook University
A drug developed by researchers at the Renaissance School of Medicine at Stony Brook University that targets enzymes involved in the development of pancreatic cancer cells is showing promise for improved treatment of metastatic pancreatic cancer.
Cardiovascular Disease Leading Cause of Death World-Wide, but Cancer Rising Cause in Rich Countries: Study
McMaster University
Cardiovascular disease (CVD) is the major cause of death among middle-aged adults around the world; however, in high-income countries deaths from cancer have become twice as frequent as those from CVD.
Back to School!
Rutgers Cancer Institute of New Jersey
From maintaining regular check-ups and keeping up to date with recommended vaccinations to a good diet and exercise, some simple tips can help keep youngsters healthy as they head back to class - and are cancer preventive too.
Leukemia: Not Just One Disease
Rutgers Cancer Institute of New Jersey
An estimated 61,780 new cases of leukemia will be diagnosed in the United States this year. Although leukemias are thought to occur in childhood, they can actually present at any age in both children and adults.
Delivering Immunotherapy Directly to Brain Tumors
Cedars-Sinai
A new study published this week gives insight into how cancer immunotherapies might one day be delivered directly to the brain in order to treat brain tumors.
Cracking the Code of a Brain Cancer That Keeps Coming Back
Cincinnati Children's Hospital Medical Center
Researchers used a powerful new computer-assisted technology called single-cell transcriptomics that measures thousands of individual cells simultaneously to map cell types and molecular cascades that drive the growth of SHH-medulloblastoma. In a study published Aug. 29 by the journal Cancer Cell
Nerves Could be Key to Pancreatic Cancer Spread
Johns Hopkins Medicine
A couple of molecules that nerve cells use to grow during development could help explain why the most common pancreatic cancers are so difficult to contain and for patients to survive
Blocking Specific Protein Could Provide a New Treatment for Deadly Form of Prostate Cancer
Perelman School of Medicine at the University of Pennsylvania
Blocking a kinase known as CDK7 sets off a chain reaction that results in the death of prostate cancer cells that have spread and are resistant to standard therapies
Birmingham Woman Meets Philadelphia Man Who Saved Her Life Through Bone Marrow Donation
Children's of Alabama
Jada Lucas, a 22-year-old bone marrow recipient from Birmingham, met the bone marrow donor who helped save her life -- Jerome Lewis of Philadelphia, Penn. -- at donor registry event at Children's of Alabama.
NRG Oncology Approves Danbury and Norwalk Hospitals as Primary Sites for Clinical Research
Nuvance Health
Danbury Hospital and Norwalk Hospital received approval to join NRG Oncology as primary clinical research sites. This means that patients at Danbury Hospital and Norwalk Hospital now have expanded access to the latest clinical trials for breast cancer, radiation oncology, and gynecologic cancer.
International Collaboration to Improve Cancer Care in Sub-Saharan Africa Announces Management of Most Adult Cancers Covered by NCCN Harmonized Guidelines
National Comprehensive Cancer Network(r) (NCCN(r))
A collaborative project from the National Comprehensive Cancer Network(r) (NCCN(r)), the African Cancer Coalition (ACC), the American Cancer Society (ACS), and others to improve cancer outcomes in Sub-Saharan Africa enters a new phase in Addis Ababa, Ethiopia, today.
Grant Awarded to Study Negative Side Effects of Cancer Treatment Medication
Boise State University
Xinzhu (Shin) Pu, an assistant research professor in Boise State University's biology department and Biomolecular Research Center, has been awarded a one-year renewable grant of $50,000 by the IDeA Network of Biomedical Research Excellence (Idaho INBRE) to fund a pilot study related to the heart-damaging effects of Doxorubicin.
Researchers to create quick, low-cost cancer diagnostic
University of Notre Dame
Researchers at the University of Notre Dame have received $2.9 million to develop a new diagnostic platform that could diagnose cancer in as little as three hours by using only one or two drops of blood.
'MasSpec Pen' for Accurate Cancer Detection During Surgery
American Chemical Society (ACS)
A major challenge for cancer surgeons is to determine exactly where a tumor starts and where it ends. Removing too much tissue can impair normal functions, but not taking enough can mean the disease could recur.
Runaway Mitochondria Cause Telomere Damage in Cells
Health Sciences at the University of Pittsburgh
Targeted damage to mitochondria produces a "Chernobyl effect" inside cells, pelting the nucleus with harmful reactive oxygen species and causing chromosomal damage.
Will Disposable Colonoscopy Devices Replace Reusables?
Johns Hopkins Medicine
As a disposable version of the instrument used in one of the most common medical procedures in the United States inches closer to widespread availability, a team of Johns Hopkins data researchers is studying the economic and safety implications associated with the devices used to perform colonoscopies.
Skin Patch Could Painlessly Deliver Vaccines, Cancer Medications in One Minute
American Chemical Society (ACS)
Melanoma is a deadly form of skin cancer that has been increasing in the U.S. for the past 30 years. Nearly 100,000 new cases of melanoma are diagnosed every year, and 20 Americans die every day from it
Researchers Develop Early Detection Test for Ovarian Cancer
Queen's University Belfast
Researchers from Queen's University Belfast have developed a test that may be able to detect ovarian cancer up to two years earlier than current approaches.
Researchers Discover How the Sun Damages Our Skin
Binghamton University, State University of New York
Researchers at Binghamton University, State University of New York have discovered the mechanism through which ultraviolet radiation, given off by the sun, damages our skin.
Yale Cancer Center finding offers hope for treatment of incurable Childhood Brain cancer
Yale Cancer Center
A team of investigators at Yale Cancer Center (YCC) have found a major chink in the armor of an incurable childhood brain cancer called Diffuse Intrinsic Pontine Gliomas (DIPG).
Revealing the Molecular Engine That Drives Pancreatic Cancer Provides Ways to Turn It Off
Georgetown Lombardi Comprehensive Cancer Center
Researchers have decoded a chain of molecules that are critical for the growth and survival of pancreatic ductal adenocarcinoma--the most common and also the most lethal form of pancreatic cancer.
Depression, Anxiety Linked to Opioid Use in Women With Breast Cancer
University of Virginia Health System
The findings should encourage doctors to better manage mental health in patients with breast cancer and spur care providers to consider alternative pain management such as physical therapy, massage and acupuncture, the researchers say.
Super-powered immune cells - leading the next cancer breakthrough
University of South Australia
Ground-breaking immune therapy promises to deliver vital evidence in the fight against cancer as researchers from the Centre for Cancer Biology open a new clinical trial using genetically engineered immune cells to treat solid cancers.
Nuclear Physics Detector Tech Used in Cancer Treatment Monitoring System
Department of Energy, Office of Science
The OARtrac(r) system includes technologies that are based on a novel application of scintillating material in fiber form. Doctors can insert these scintillating fibers into the human body via a catheter to monitor the radiation that cancer patients receive in a range of hard-to-reach areas.
The challenge: Make and purify a medical isotope that must be used the same day
University of Alabama at Birmingham
A DOE grant will help solve a production roadblock for the medically useful radioactive isotopes scandium 43 and scandium 47. If available, they could visualize and destroy solid tumors. But with a half-life of 4 hours, scandium 43 must be made, purified and then used in a PET scan in a single day.
Antibiotics Exposure Linked to Increased Colon Cancer Risk
Johns Hopkins Medicine
In an extensive "data mining" analysis of British medical records, researchers at the Johns Hopkins Kimmel Cancer Center conclude that taking even a single course of antibiotics might boost--albeit slightly--the risk of developing colon cancer--but not rectal cancer--a decade later. The findings, reported in the August 20 issue of the journal Gut, highlight the need for judicious use of this broad category of drugs, which are frequently improperly or overprescribed, the report authors say.
New Jersey's First National Cancer Institute Community Oncology Research Program (NCORP) Awarded to Atlantic Health Cancer Consortium
Atlantic Health System
The National Cancer Institute (NCI) has designated Atlantic Health System as a National Community Oncology Research Program (NCORP) site of the Atlantic Health Cancer Consortium (AHCC). As New Jersey's first and only NCORP, AHCC will help develop and implement NCI cancer prevention, screening, care delivery and treatment studies with leading health care systems across the state.
Helping Skin Cells Differentiate Could Be Key to Treating Common Skin Cancer
Perelman School of Medicine at the University of Pennsylvania
A new study from Penn researchers has identified a key regulator of a process that controls skin regeneration, which can control whether cells turn into a common skin cancer.
Moving Mountains for Multiple Myeloma: Nina Shah Traverses Iceland to Benefit Myeloma Research
UCSF Helen Diller Family Comprehensive Cancer Center
Earlier this month, Nina Shah, MD, joined other myeloma patients, caregivers, and clinical providers on a three-day trek across Iceland's spectacular landscape.
Huntsman Cancer Institute Introduces Cancer Screening and Education Bus to the Community
Huntsman Cancer Institute at the University of Utah
Today Huntsman Cancer Institute (HCI) at the University of Utah unveiled the Cancer Screening and Education bus. This new, state-of-the-art mobile outreach clinic brings HCI's clinical and educational expertise and the latest screening technology to residents across Utah, including those who live in distant geographic areas and rural communities.
Parental Roadblocks for Teens Receiving HPV Vaccines
University of Alabama at Birmingham
CWRU School of Nursing Awarded $2.14M National Cancer Institute Grant
Case Western Reserve University
With a $2.14 million grant from the National Cancer Institute (NCI), researchers from the Frances Payne Bolton School of Nursing at Case Western Reserve University will measure whether an approach that uses simulation or experiential learning can affectively teach family caregivers not only the skills to take better care of their patient, but better care of their own emotional and physical health amid such incredible stress.
Research on Cellular 'Packages' Receives $900k in Federal Funding
Johns Hopkins Medicine
Scientists from Johns Hopkins and elsewhere have been selected to receive more than $940,000 to study cellular "packages" that can be used to diagnose disease, track disease status and potentially deliver therapies. The packages, called extracellular vesicles, are ubiquitous among all types of human cells and are being studied for their use in cancer, neurocognitive disorders and other conditions.
Laboratory Studies Identify A Potential Way to Treat Human Cancers With ARID1A Mutations
Johns Hopkins Medicine
A new study shows that tumor cells depleted of ARID1A -- a protein that acts as a cancer suppressor -- become highly sensitive to anticancer poly ADP ribose polymerase (PARP) inhibitor drugs after radiation treatment. The research, led by Johns Hopkins Kimmel Cancer Center researchers, could advance efforts to treat many human cancers with loss of ARID1A that are resistant to current standard treatments, the study team suggests.
Maintaining Full Doses of Chemotherapy Can Be Key for Breast Cancer Survival, According to New Research in JNCCN
National Comprehensive Cancer Network(r) (NCCN(r))
Study in JNCCN--Journal of the National Comprehensive Cancer Network, finds early dose reduction of adjuvant FEC-D chemotherapy negatively impacts overall survival rates for women with intermediate- or high-risk breast cancer.
Study Finds Lack of Racial Diversity in Cancer Drug Clinical Trials
Baylor University
New research published this week in JAMA Oncology has found a lack of racial and ethnic diversity in clinical trials for cancer drugs. It raises concerns about the effectiveness of cancer drugs in some patients, especially since genetic differences may affect how a patient responds to a drug.
MedStar Washington Hospital Center Medical-Surgical Unit Receives AMSN PRISM Award(r) for Exemplary Practice
MedStar Washington Hospital Center
The 5E Medical Oncology/Hematology Unit at MedStar Washington Hospital Center has received the prestigious AMSN PRISM Award(r), an honor recognizing exceptional nursing practice, leadership, and outcomes in hospital medical-surgical units. The award, which stands for "Premier Recognition In the Specialty of Med-Surg," is the first of its kind honoring med-surg nursing units in the United States and internationally.
Discovery of How Cells Override Genetic Changes Could Lead to New Approaches in Pancreatic Cancer Treatment
Huntsman Cancer Institute at the University of Utah
A discovery by scientists at Huntsman Cancer Institute (HCI) at the University of Utah (U of U) could lead researchers to a more effective way to treat pancreatic cancer. Their findings were published today in Developmental Cell.
CANDLE Illuminates New Pathways in Fight Against Cancer
Department of Energy, Office of Science
As part of the Department of Energy's role in the fight against cancer, scientists are building tools that use supercomputers to solve problems in entirely new ways.
Drug accelerates blood system's recovery after chemotherapy, radiation
University of California, Los Angeles (UCLA), Health Sciences
A drug developed by UCLA physician-scientists and chemists speeds up the regeneration of mouse and human blood stem cells after exposure to radiation. If the results can be replicated in humans, the compound could help people recover quicker from chemotherapy, radiation and bone marrow transplants.
Nanocapsule Reaches Cancer That Has Spread to Central Nervous System in Mice
University of California, Los Angeles (UCLA), Health Sciences
Researchers developed a drug delivery system that can break through the blood-brain barrier in mice.
Henry Ford Cancer Institute Enrolls First Patient in World's Largest Brain Cancer Clinical Trial
Henry Ford Health System
A next-generation clinical trial program and the first-ever adaptive platform trial for brain cancer, GBM AGILE is a move away from the traditional, one-size-fits-all approach to clinical trials - a major step forward for Precision Medicine.
New drug shows encouraging survival in pancreatic cancer
Michigan Medicine - University of Michigan
A phase 1 clinical trial testing a new drug in pancreatic cancer had promising initial results, report researchers from the University of Michigan Rogel Cancer Center. The trial looked at AZD1775, an inhibitor designed to block an enzyme called Wee1, which plays a role in DNA damage repair.
Exercise associated with benefit to patients with advanced colorectal cancer
Dana-Farber Cancer Institute
Patients with metastatic colorectal cancer who engaged in moderate exercise while undergoing chemotherapy tended to have delayed progression of their disease and fewer severe side effects from treatment, according to the results of a new study.
Roswell Park Secures More Than $15.4 Million in New Funding for Cancer Research
Roswell Park Comprehensive Cancer Center
Roswell Park researchers have received recent grant awards totaling more than $15.4 million. These competitive awards include the first National Institutes of Health funding to study a new electronic tobacco device and a state grant supporting Roswell Park's work with the national Cancer Moonshot.
Roswell Park Researchers Identify Immune Biomarker of Response in Patients With Advanced Liver Cancer
Roswell Park Comprehensive Cancer Center
Roswell Park researchers have uncovered a biomarker that may help explain why some patients respond better than others to sorafenib, a chemotherapy commonly prescribed for patients with advanced liver cancer.
Case Comprehensive Cancer Center Director Elected Senior Member of the National Academy of Inventors
Case Western Reserve University
The National Academy of Inventors (NAI) has named 54 academic inventors to the Spring 2019 class of NAI Senior Members, including Stanton L. Gerson, MD, Director of the Case Comprehensive Cancer Center (Case CCC).
Single Enzyme Helps Drive Inflammation in Mice, Provides Target for New Sepsis Drugs
University of California San Diego Health
UC San Diego researchers discovered that removing a single enzyme in mice dramatically boosts survival from sepsis, an often fatal over-reaction of the immune system to infection. The finding provides a new and unexpected therapeutic target for new drug development.
Research Into RNA-DNA 'R-Loops' Could Shed Light on Cancer Formation
Texas State University
Accumulation of unusual RNA-DNA hybrids, known as R-loops, are often associated with cancers. Xiaoyu Xue, assistant professor in the Department of Chemistry and Biochemistry at Texas State University, is heading a research study examining the role of the human motor protein Aquarius (AQR) in resolving R-loops to gain insight into possible avenues of cancer prevention.
Doctors at NYU Langone Hospital-Brooklyn Help Patient with Rare Stomach Cancer Turn His Life Around
NYU Langone Hospital - Brooklyn
Louis Battaglia's doctors initially could not determine the source of his pain, until he saw specialists at NYU Langone Hospital-Brooklyn, who found it was a rare form of stomach cancer.
Inherited pancreatic cancer risk mutation identified
Dana-Farber Cancer Institute
The discovery of the previously unknown mutation, reported in Nature Genetics by investigators from Dana-Farber/Brigham and Women's Cancer Center, could lead to routine testing of individuals with a strong family history of pancreatic cancer to determine if they carry the mutation, occurring in the gene known as RABL3.
Manipulating Dose, Timing of Two Therapies Significantly Reduces Relapse in Mouse Models of Breast Cancer, Lung Cancer
UT Southwestern Medical Center
Changing the standard dose and timing of two therapies greatly cut tumor relapse and reduced side effects in mouse models of kinase mutated breast cancer and lung cancer.
Study Proves Hepatitis C Drugs Reduce Liver-Related Deaths by Nearly Half
UT Southwestern Medical Center
A new study from the UT Southwestern Simmons Comprehensive Cancer Center demonstrates that antiviral drugs for hepatitis C reduce liver-related deaths by nearly 50% in patients with a history of liver cancer.
Artificial Intelligence Could Yield More Accurate Breast Cancer Diagnoses
University of California, Los Angeles (UCLA), Health Sciences
UCLA researchers have developed an artificial intelligence system that could help pathologists read biopsies more accurately and to better detect and diagnose breast cancer.
Adding MS Drug to Targeted Cancer Therapy May Improve Glioblastoma Outcomes
University of California San Diego Health
The multiple sclerosis drug teriflunomide, paired with targeted cancer therapy, markedly shrinks patient-derived glioblastomas grown in mice by reaching stem cells at the tumor's root, according to a new UC San Diego School of Medicine study published in Science Translational Medicine.
Scientists Uncover the Intricacies of the "On/Off Switch" that Creates Cell Differentiation
New York University
A team of biologists has discovered how cells become different from each other during embryogenesis, a finding that offers new insights into genetic activity and has implications for better understanding the onset of disease and birth defects.
Bacteria on Tumors Influences Immune Response and Survival of Patients with Pancreatic Cancer
University of Texas M. D. Anderson Cancer Center
MD Anderson researchers find tumor microbiome influences immune response and patient survival in pancreatic cancer. Study points to fecal transplant as possible treatment.
Pancreatic Cancer: Less Toxic, More Enduring Drug May Improve Therapy
Columbia University Irving Medical Center
A new drug that penetrates the protective barrier around pancreatic cancers and accumulates in malignant cells may improve current chemotherapy, a study in mice suggests.
A New Pathway: Researchers Identify Potential Treatment Target for Crohn's Disease
Case Western Reserve University
There is no cure for the more than 1.6 million people in the United States living with Crohn's disease (CD) and its symptoms, including abdominal pain, intestinal distress and severe weight-loss. CD is a form of inflammatory bowel disease (IBD) in which the body's own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of the disease in its acute phase and managing it in remission. But recently, researchers at Case Western Reserve University School of Medicine identified a pathway in the immune system activated in CD and which holds promise for investigating new treatments.
Predicting the risk of cancer with computational electrodynamics
Argonne National Laboratory
A team of researchers from Northwestern University is using Argonne supercomputers to develop a low-cost, high-throughput optical microscopy technique capable of detecting macromolecular alterations for predicting and quantifying cancer risks at extremely early stages.
MD Anderson to expand Proton Therapy Center
University of Texas M. D. Anderson Cancer Center
The University of Texas MD Anderson Cancer Center unveiled plans to expand its Proton Therapy Center during a groundbreaking ceremony. The expansion will more than double the center's size to more than 160,000 square feet - almost the size of three football fields - allowing more patients greater access to the most advanced and precise form of radiation therapy.
Rutgers Develops Cancer Health Justice Lab in Newark
Rutgers School of Public Health
The Cancer Health Justice Lab (CHJL) at the Rutgers School of Public Health has launched a series of educational programming on cancer information, prevention, and treatment.
Jersey Shore University Medical Center Foundation Welcomes New Trustee
Hackensack Meridian Health
Hackensack Meridian Health Jersey Shore University Medical Center Foundation is pleased to announce the addition of Phil Scaduto to the Jersey Shore University Medical Center Foundation board of trustees.
Free, Plow To Plate Meals Nourish Cancer Patient and Caregiver
Western Connecticut Health Network
Diane and Phil Hannah of New Milford, Connecticut faced a series of health problems -- including Phil's skin cancer diagnosis -- that made it difficult for them to keep up with everyday tasks, like shopping for groceries and preparing meals. The Eating Well program supported Diane and Phil during this challenging time by providing vouchers for free, nutritious meals from the New Milford Hospital cafe after each of Phil's radiation therapy sessions. The Eating Well program aims to improve the overall well-being of patients and caregivers, and is fully supported by generous donors. Eating Well is a component of New Milford Hospital's Plow to Plate program. Plow to Plate meals are freshly prepared with locally sourced, organic ingredients.
UCLA Study Links Progenitor Cells to Age-Related Prostate Growth
University of California, Los Angeles (UCLA), Health Sciences
The prostates of older mice contain more luminal progenitor cells -- cells capable of generating new prostate tissue -- than the prostates of younger mice, UCLA researchers have discovered.
$1.5M Awarded from ORIEN New Oncologic Visionary Awards Program Supports Research by Rutgers Cancer Institute Investigators
Rutgers Cancer Institute of New Jersey
A pair of Rutgers Cancer Institute of New Jersey physician-scientists are collaborating on national research projects that received $1.5 million in combined funding from the Oncology Research Information Exchange Network(r) (ORIEN) New Oncologic Visionary Awards (NOVA) program.