Expert Directory
Tim Hansen, Master of Engineering, B.S. Chemical Engineering
Director, Cleantech Engineering Services
Southern ResearchBiofuels,Clean Fuel,clean technology,Energy Storage,Energy technology,environmental technologies,Greenhouse Gas Emissions,Renewable Energy,Sustainable Chemistry,sustainable technology
Tim Hansen, P.E., has 20 years of experience in management of environmental and energy technology development and demonstration and multimedia environmental engineering. In his role as director of Cleantech Engineering Services for E&E, he is responsible for development and operation of a regional office focused on research, development, and demonstration of innovative energy, environmental, and sustainable technologies. Hansen’s primary technical focus has been the development and management of large technology evaluation programs in the advanced energy, transportation, and climate change areas – focusing on clean vehicles and fuels, energy efficiency technologies, and renewable energy systems. His chief interests have focused on technologies that reduce greenhouse gas emissions and provide economic benefits to users. Hansen’s group also focuses on developing innovative solutions and intellectual property in the areas of biofuels, sustainable chemistry, energy storage, and chemical process technology for production of cleaner fuels and chemicals. Prior to Southern Research, Hansen worked as an environmental consultant, seeking improved environmental performance and regulatory compliance for industrial clients. He has a master’s degree in engineering from the Thayer School of Engineering at Dartmouth College and a bachelor’s degree in chemical engineering from the University of Virginia. He is also a Registered Professional Engineer.
Rita Cowell, Ph.D .in Neuroscience, B.S. in Biology
Fellow & Chair, Neuroscience Department
Southern ResearchALS,Alzheimer's,Alzheimer's Disease,Amyotrophic Lateral Sclerosis,Depression,Huntington Disease,Neurological Disorders,Parkinson's,Parkinson's Disease,Schizophrenia
Dr. Rita Cowell is Fellow and Chair of the Neuroscience Department within the Drug Discovery Division. In this role, she maintains an independently-funded research program, while overseeing the Neuroscience Department with the mission of discovering novel, mechanism-based approaches to treat individuals with neurodegenerative disorders. The research in the Cowell Lab aims to determine how intrinsic transcriptional programs underlying neuronal heterogeneity give rise to selective vulnerability in neurodegenerative disorders such as Parkinson’s Disease, Huntington Disease, Amyotrophic Lateral Sclerosis, and Alzheimer’s Disease. Her research group is comprised of postdoctoral, graduate, and undergraduate trainees who are affiliated with Southern Research’s partner institution, the University of Alabama at Birmingham (UAB). The lab is currently supported by grants from the National Institutes of Health and the Michael J. Fox Foundation for Parkinson’s Research. Cowell received her undergraduate degree in biology in 1997 from the University of Illinois at Urbana-Champaign and her Ph.D. in neuroscience in 2002 from the University of Michigan, where she also completed her postdoctoral work. She began her independent research laboratory as an assistant professor at UAB in 2006, rising through the ranks to associate professor. She also served as co-director of the Neuroscience Graduate Theme for the Program in Biomedical Sciences at UAB and associate director for Communications and Outreach for the Civitan International Research Center before joining Southern Research in 2017. Using a think tank-like model, she now directs the Neuroscience Department, utilizing its collective expertise in mechanisms of cell death/dysfunction and animal models of disease to identify and prioritize novel targets for small molecule identification using the unique high throughput capabilities of the Drug Discovery Division. Beyond these efforts to the institution, she actively facilitates interactions with local, national, and international groups interested in drug discovery and development in the neurosciences by serving as a liaison and consultant for extramural collaborations. Ongoing collaborations exist with scientists from UAB, HudsonAlpha in Huntsville, Alabama, and numerous other institutions, universities, and companies across the world. Cumulatively, her goal is to lead transformation of drug discovery in the field of neurodegeneration and to improve the lives of those suffering from these diseases.
Asian American,Pacific Islanders
Christina Chin is anticipating the Aug. 15 opening of the romantic comedy “Crazy Rich Asians” and the insights the film offers into the Asian American second-generation experience. The film, based on the book of the same name by Kevin Kwan, is the first from a major Hollywood studio to feature an entirely Asian cast in a present-day story since the release 25 years ago of “The Joy Luck Club.” Chin, who has previewed the film, notes that the story it tells goes beyond money and wealth to highlight universal themes about love, friendship and negotiating family dynamics “that transcend ethnic and racial boundaries.” The assistant professor of sociology is co-author of a widely reported 2017 study “Tokens on the Small Screen” about how Asian Americans and Pacific Islanders remain underrepresented on television. She and scholars from five other universities collaborated on the study, a 10-year follow-up to and expansion of an earlier study of Asian Americans and Pacific Islanders on prime-time series television. Chin’s teaching and scholarly research interests include immigration, racial and ethnic identity, youth and popular culture. Chin is co-editor of "Asian American Sporting Cultures" (NYU Press -2016). Chin earned her doctorate at UCLA. Prior to joining the Cal State Fullerton faculty, she was a postdoctoral fellow for the Asian American Studies Department at the University of Illinois, Urbana-Champaign.
Abuse & Trauma,Domestic Violence,Gun Control,Gun Control Laws,Gun Violence,Health Outcomes,Homicide,intimate partner abuse,intimate partner homicide,Intimate Partner Violence,Johns Hopkins,Nurse,Nursing,Pregnancies,Research,Women's Health
Jacquelyn Campbell is a national leader in research and advocacy in the field of domestic violence or intimate partner violence (IPV). Her expertise is frequently sought by national and international policy makers in exploring IPV and its health effects on families and communities. Her most recent research in health sequelae has been foundational for the areas of the intersection of HIV and violence against women and how head injuries and strangulation from intimate partner violence can result in undiagnosed and untreated Traumatic Brain Injury. She has consistently advocated for addressing health inequities of marginalized women in this country and globally affected by experiences of violence. She has served as Principle Investigator on 14 federally funded collaborative research investigations through the National Institutes of Health, National Institutes of Justice, Department of Defense, the Department of Justice (Office of Violence Against Women), and Centers for Disease Control to examine intimate partner homicide and other forms of violence against women as well as interventions and policy initiatives to improve the justice and health care system response. This work has paved the way for a growing body of interdisciplinary knowledge about experiences of violence and health outcomes, risk assessment for lethal and near-lethal domestic violence, and coordinated system (justice, social services, and health) responses to address intimate partner violence. Dr. Campbell has published more than 270 articles, 56 book chapters and seven books, in addition to developing the Danger Assessment, an instrument to assist abused women in accurately determining their level of danger. The Danger Assessment is also the basis of the Lethality Assessment Program (MNADV LAP) for first responders to assess risk of homicide of domestic violence survivors and connect those at high risk with domestic violence services. In collaboration with Dr. Nancy Glass, originator of myPlan, a decision aid for IPV survivors, she is leading an NIH-funded cultural adaptation of myPlan for immigrant and indigenous women. Elected to the Institute of Medicine in 2000, Dr. Campbell also was the Institute of Medicine/American Academy of Nursing/American Nurses' Foundation Senior Scholar in Residence and was founding co-chair of the IOM Forum on the Prevention of Global Violence. Other honors include the Pathfinder Distinguished Researcher by the Friends of the National Institute of Health National Institute for Nursing Research, Outstanding Alumna and Distinguished Contributions to Nursing Science Awards, Duke University School of Nursing, the American Society of Criminology Vollmer Award, and being named one of the inaugural 17 Gilman Scholars at Johns Hopkins University. She is on the Board of Directors for Futures Without Violence, is an active member of the Johns Hopkins Women’s Health Research Group, and has served on the boards of the House of Ruth Battered Women's Shelter and four other shelters. She was a member of the congressionally appointed U.S. Department of Defense Task Force on Domestic Violence.
Aging,Aging In Place,Community Health,Gerontolgoy,health care savings,health disparites,Health Policy,Housing,housing access,low-income communities,Nurse,Nurse Practitioner,Nursing Home,Occupational Therapist,Older Adults
A number of years ago, while making house calls as a nurse practitioner to homebound, low-income elderly patients in West Baltimore, Sarah Szanton noticed that their environmental challenges were often as pressing as their health challenges. Since then she has developed a program of research at the Johns Hopkins School of Nursing on the role of the environment and stressors in health disparities in older adults, particularly those trying to “age in place” or stay out of a nursing home. The result is a program called CAPABLE, which combines handyman services with nursing and occupational therapy to improve mobility, reduce disability, and decrease healthcare costs. She is currently examining the program's effectiveness through grants from the National Institutes of Health and the Innovations Office at the Center on Medicaid and Medicare Services. She is also conducting a study, funded by the Robert Wood Johnson Foundation, of whether food and energy assistance improve health outcomes for low-income older adults. A former health policy advocate, Dr. Szanton aims her research and publications toward changing policy for older adults and their families.
Animal Behavior,Animal Models,Aversion,Binge Drinking,Drug Treatment,genetics and addiction,Reward,Risk Factors,Taste
I have been working at the VA Medical Center and in the Department of Behavioral Neuroscience at the Oregon Health & Science University in Portland since 1979. I entered graduate school at the University of Colorado to obtain a Ph.D. in social psychology. Fortuitously, I was sidetracked into instead studying behavioral neuroscience (AKA biopsychology) at the fledgling Institute for Behavioral Genetics in Boulder. I’ve been pretty much surrounded by mice ever since. I did post-doctoral work at the University of Wisconsin- Milwaukee and was a Lecturer in Psychology at San José State and then UC-Santa Barbara, and then held a two-year research position at a Dutch pharmaceutical company in the Dutch hinterlands before Portland. My research interest is in understanding individual differences in behavioral susceptibility to alcohol and other drugs of abuse, and their genetic and neurobiological bases. Most recently, I’ve been breeding mice that voluntarily drink alcohol until they become intoxicated, i.e. developing a mouse model of university students. I’m working with collaborators to figure out how many genes we’ve affected in the process, which ones they are, and what their biological functions are. We’re using that information to try to predict some drugs that are already FDA approved that might be re-purposed to try as treatments for alcoholism. My expertise is in mouse behavioral tests that try to capture human traits such as anxiety, sensitivity to drug’s rewarding or aversive effects, incoordination, learning and memory, novelty-seeking, and so forth. I am less fluent in rat than in mouse but the languages are related. I am familiar with psychiatric genetics/human genetics methods, but not really expert in the more esoteric of them. I am also familiar with the big data/genomics/informatics approaches, but again not really expert there, either.
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Dr. Lara Ray received her PhD in Clinical Psychology from the University of Colorado at Boulder. During her graduate degree she completed interdisciplinary training in behavioral genetics and neuroscience. Dr. Ray completed a predoctoral clinical internship at Brown University Medical School where she stayed for a postdoctoral fellowship at the Brown University Center for Alcohol and Addiction Studies. After her postdoctoral fellowship, Dr. Ray joined the faculty at the UCLA Clinical Psychology Program where she is now a Full Professor. Dr. Ray also has academic appointments in the UCLA Department of Psychiatry and Human Behavior and the UCLA Brain Research Institute. Dr. Ray has an active program of research on clinical neuroscience of addiction. Her laboratory combines experimental psychopharmacology with behavioral genetic and neuroimaging methods to ascertain the mechanisms underlying addictive disorders in humans and applying these insights to treatment development. Dr. Ray has over 150 peer-reviewed publications and book chapters. Her program of research is funded by the National Institute on Alcohol and Abuse and Alcoholism (NIAAA) as well as the National Institute on Drug Abuse (NIDA). Dr. Ray’s current interest centers around the clinical science informed translation of neurobiological models of addiction to clinical samples. Dr. Ray has received awards from the American Psychological Association (APA) for early career contributions to the science of addiction, including awards from the Society of Addiction Psychology (APA div 50), the Society of Clinical Psychology (APA div 12), and the Research Society for Alcoholism.
Alcohol,HIV,Inflamation,metabolic alterations ,Muscle,TBI
Patricia E. Molina, MD, PhD, is the Richard Ashman Professor and Head of Physiology, and Director of the Alcohol and Drug Abuse Center at LSU Health Sciences Center New Orleans’ School of Medicine. Dr. Molina's training as a physician prior to completing training in physiology provides her with a unique systems approach to study the biomedical consequences of chronic heavy alcohol use, with emphasis on the pathophysiological mechanisms that aggravate HIV disease progression. Her research focuses on the interaction of chronic alcohol consumption on progression of HIV disease in preclinical models and in translational studies. Her research involves integrating in vivo with ex vivo approaches to understand the contribution of organ systems to disease pathogenesis. Another area of research interest and ongoing investigations is the interaction of alcohol with outcomes from traumatic brain injury. Her work examines the mechanisms that lead to greater alcohol drinking during the post-injury phase, and the potential role of the endocannabinoid system in modulating those responses. Dr. Molina is interested in translating research findings to the community at large, and in educating the lay public on the consequences of excessive alcohol consumption. This is particularly relevant to young students and parents as they make decisions on alcohol drinking throughout their life.
,Alcohol Use,Alcohol Use Disorder,harm reduction,Mindfulness,Statistics
Dr. Katie Witkiewitz is a Professor of Psychology at the University of New Mexico with a joint appointment at the Center on Alcoholism, Substance Abuse, and Addictions. The underlying theme of her research is the development of empirically-based models of alcohol use disorder, with an emphasis on harm reduction and the application of person-centered models to better understand individual changes in alcohol use over time. Her recent work has focused on novel definitions of alcohol use disorder treatment outcomes that focus on reductions in drinking, as an alternative to an abstinence-only model of alcohol recovery. Dr. Witkiewitz is also a licensed clinical psychologist and has worked extensively on the development of a theoretical model of biopsychosocial influences on alcohol use and relapse. This research has led to her collaborative work on the development and evaluation of mindfulness-based interventions for alcohol and drug use disorders. She has conducted numerous empirical studies on the prediction of alcohol and drug relapse following treatment, mechanisms of successful alcohol treatment outcomes, as well as the development of behavioral interventions to treat addiction. Her research has been supported by grants from the National Institute on Mental Health, the National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Alcoholism and the National Cancer Institute, totaling over $22 million in research funding since 2004. Dr. Witkiewitz was born in Rochester New York and graduated Summa Cum Laude with a Bachelor of Arts degree in psychology from the State University of New York at Potsdam in 1999. She completed a Masters of Arts degree at the University of Montana in 2000 and her doctoral degree at the University of Washington in 2005 under the direction of Dr. G. Alan Marlatt. To date, she has authored 5 books, over 185 peer-reviewed publications and book chapters, and she has given over 75 presentations and invited talks.
Ralph Hingson, ScD, MPH
Division of Epidemiology and Prevention Research
Research Society on AlcoholismAlcohol,College Drinking,epidemiolgy,Policy,Prevention,program evaluation,Underage Drinking
Dr. Ralph Hingson is the Director of the Division of Epidemiology and Prevention Research at the National Institute on Alcohol Abuse and Alcoholism (NIAAA). Before joining NIAAA, he was Professor and Associate Dean for Research at the Boston University School of Public Health. He has authored or co-authored 170 research articles and book chapters, including studies of the effects of: (1) Raising the legal drinking age, (2) Zero tolerance laws for drivers under 21, (3) .08% legal blood alcohol limits for adult drivers, (4) comprehensive community programs to reduce alcohol problems, (5) early drinking onset on alcohol dependence, traffic crashes, unintentional injuries and physical fights after drinking, as well as 6) assessments of morbidity and mortality associated with underage drinking, drinking by U.S. college students ages 18-24, and interventions to reduce both underage and college drinking. Dr. Hingson currently serves on the World Health Organization coordinating council to implement WHO’s global strategic plan to reduce the harmful use of alcohol. In recognition of his research contributions, the Robert Wood Johnson Foundation honored Dr. Hingson in 2001 with its Innovators Combating Substance Abuse Award. In 2002, he received the Widmark Award, the highest award bestowed by the International Council on Alcohol Drugs and Traffic Safety (ICADTS). Dr. Hingson is a Past President of ICADTS. In 2003, Mothers Against Drunk Driving instituted the Ralph W. Hingson Research in Practice Annual Presidential Award, with Dr. Hingson honored as its first recipient. In 2008, the American Society of Addiction Medicine conferred the R. Brinkley Smithers Distinguished Scientist Award to Dr. Hingson. In 2014, he received the University of Pittsburgh Legacy Laureate Award. In 2016, he received ICADTS’ Borkenstein Award for “Outstanding contributions to international cooperation in alcohol and drug related traffic safety programs.” In September of 2017, Dr. Hingson will receive will receive a National Institutes of Health (NIH) 2017 Director's Award for his role as a member of the Surgeon General's Report Team for the recently-released Surgeon General’s Report on Alcohol, Drugs, and Health.
Alcohol Consumption,alcohol tolerance,genetics and addiction,Neurobiology
Professor, Department of Pharmacology, University of Colorado School of Medicine, Aurora, CO. Research has focused on neural mechanisms of adaptation to alcohol, including tolerance and dependence. Identified a role of peptide hormones and brain growth factors to modify alcohol tolerance. Discovered that one subtype of glutamate receptor, the NMDA receptor, is very sensitive to alcohol, and that increases in NMDA receptor function are involved in alcohol dependence. This work has led to many further studies by others that focus on the role of the brain glutamate systems in addiction to alcohol and other drugs. Currently focus on systems genetic analysis, using "big data" to understand the genetic contribution to alcohol-related and other complex behaviors.
Alcohol
Kenneth J. Sher, Ph.D., is a nationally renowned scholar, researcher, and mentor whose work has greatly advanced our understanding of the etiology and course of alcohol use disorder (AUD), particularly as it relates to personality traits and their evolution. Dr. Sher has been at the forefront of research on personality, alcohol misuse among college students, and the behavioral pharmacology of alcohol. He is also a highly regarded expert in longitudinal research methodology. Over the course of his career, Dr. Sher has studied a wide range of topics contributing substantially to our understanding of the development of alcohol and other substance misuse. He has examined risk mechanisms that influence AUD onset and progression, premorbid predictors of future AUD (e.g., cognitive mechanisms and individual differences in the psychopharmacological responses to alcohol), and the involvement of family history of alcoholism in multiple etiological pathways to AUDs. His diverse research interests include: personality, as well as developmental changes in personality, as predictors of alcohol misuse and AUD; gene-environment interactions in the development of AUD; and predictors and consequences of binge drinking and alcohol misuse among college students (including 21st birthday drinking and other extreme drinking occasions). Dr. Sher has also investigated the phenomenon of “maturing out” of alcohol problems, demonstrating that maturing out is associated with differences in age-related personality changes that are accompanied by decreased impulsivity and neuroticism and is not merely a consequence of constrained opportunity occasioned by the assumption of adult roles. Dr. Sher had led two major ongoing longitudinal cohort studies that have followed individuals beginning in their freshman year of college and into mid-life. In addition to the development of AUD, this research tracks drug use and comorbid psychiatric disorders. A particularly innovative aspect of this work is the incorporation of genotyping which may provide key information on individual differences in susceptibility to AUD. In addition to using traditional survey approaches, Dr. Sher’s research employs event-based data to capture the momentary moods, motivational states, and cues that precede drinking events. This work is critical to understanding transient influences on drinking behavior and related consequences on a given occasion. A major focus of his current work is the critical evaluation of existing diagnostic approaches and development of empirically-based criteria and algorithms for AUD diagnosis. This research holds promise for improving AUD diagnosis in clinical practice, and advancing research on the causes and correlates of AUD. Dr. Sher has been continually funded by NIAAA for more than 30 years. He has had more than 250 papers published in peer-reviewed journals and he has authored and edited several books. Dr. Sher earned his undergraduate degree from Antioch College, his Ph.D. in clinical psychology from Indiana University, and completed clinical internship training at Brown University. He is the Curators’ Distinguished Professor of Psychological Sciences at the University of Missouri, where he directs a pre and postdoctoral training program in alcohol research.
Alcohol,Alcoholism,Drug Abuse,Mental Health
Tom Greenfield, PhD, is Scientific Director of the Public Health Institute’s Alcohol Research Group, in Emeryville California, which involves 15 multi-disciplinary research scientists bringing a broad range of expertise to bear on alcohol, other drug and mental health problems. Since 1995 Greenfield led and now co-lead the bi-decadal National Alcohol Surveys (NASs) conducted by the NIAAA-funded National Alcohol Research Center, that he directed from 1999 to 2015 (P50 AA005595, Years 20-35). Over time, the NAS has incorporated measures and interview modalities that he helped refine in a series of methodological studies. Greenfield trained as a clinical psychologist, afterwards adding epidemiological and health services expertise in part through postdoctoral years at the UCSF Department of Psychiatry. Educated at Caltech, MIT and the University of Michigan, he has authored or coauthored over 250 peer-reviewed articles, chapters, books and monographs. Many are on health effects of alcohol and alcohol policy, often in collaboration with senior colleagues, early career scientists, and postdoctoral fellows. In addition to participating in many national and international projects, Dr. Greenfield has led numerous R-mechanism National Institutes of Health projects on such topics as alcohol policy evaluation, health disparities and alcohol-related mortality, alcohol intake measurement, and comparative cross-national studies. He currently leads two team-based Alcohol's Harms to Others R01 grants funded by NIAAA. One, together with his ARG colleague Dr. Katherine Karriker-Jaffe, examines ways that secondhand drinking can victimize partners, families, children, coworkers, and communities, using metrics such as the damage to mental health, health quality of life, and a family’s finances. A second is a similar multinational collaboration involving standardized questionnaires in over 30 countries that surveyed victims and perpetrators of alcohol’s harms, and involves multiple PIs and 15 international co-investigators. Both grants are examining in depth state and national policies, contextual, and protective influences, and ways to best reduce the toll of alcohol’s harms to communities. Selected recent publications: Wilsnack, S.C., Greenfield, T.K., Bloomfield, K.A., (in press). The GENAHTO Project (Gender and Alcohol's Harm to Others): design and methods for a multinational study of alcohol's harm to persons other than the drinker. International Journal of Alcohol & Drug Research. Greenfield, T. K. & Martinez, P. (2017) Alcohol as a risk factor for chronic disease: raising awareness and policy options. In: Giesbrecht, N. & Bosma, L. (Eds.), Preventing Alcohol-Related Problems: Evidence and Community-based Initiatives (pp 33-50). Washington, DC: APHA Press. Greenfield, T.K., Ye, Y., Lown, E.A., Cherpitel, C.J., Zemore, S., & Borges, G. (2017) Alcohol use patterns and DSM-5 alcohol use disorder on both sides of the US-Mexico border. Alcoholism: Clinical & Experimental Research 41:769-778. [DOI: 10.1111/acer.13356] PMICD: PMC5378627 Greenfield, T.K., Karriker-Jaffe, K.J., Kerr, W.C., Ye, Y., & Kaplan, L.M. (2016) Those harmed by others’ drinking are more depressed and distressed, Drug and Alcohol Review, 35(1):22-29 [doi: 10.1111/dar.12324]. PMCID: PMC4775452 Greenfield, T.K., Bond J., Kerr W.C. (2014) Biomonitoring for improving alcohol consumption surveys: the new gold standard? Alcohol Research: Current Reviews 36(1): 39-44. PMCID: PMC4432857 Greenfield, T. K. (2013) [Editorial] Alcohol (and other drugs) in public health research. American Journal of Public Health 103(4):582.
Drug Discovery,Gene Expression and Regulation,immune signaling,Neuroscience,Receptor Proteins
I have almost 40 years of experience in the field of alcoholism research, with much of my work focusing on the molecular sites and mechanisms of alcohol action in brain. My group has extensive experience with mouse behavioral models of alcohol consumption and dependence and was involved in some of the initial studies of the neuroimmune basis of alcohol dependence. Profiling brain gene expression is key to understanding addiction, and we were among the first to study the human brain transcriptome. We have implemented microRNA profiling and next-generation sequencing to extend our studies of molecular remodeling by alcohol in human and mouse brain. We study the genetic overlap in human alcoholics and animal models of alcohol dependence and examine the neurobiological systems involved. My research encompasses the fields of genomics, behavior, systems biology, and bioinformatics. Overall, my work has combined functional, structural, behavioral, and genomic approaches to define sites of alcohol action. Currently, I am Associate Director of the Waggoner Center for Alcohol and Addiction Research at The University of Texas at Austin and previously served as Director for 20 years. I am also the Consortium Director for the Integrative Neuroscience Initiative on Alcoholism (INIA)-Neuroimmune, where our goal is to identify and test candidate drugs that may be repurposed to treat alcohol use disorders.
Dr. Amitai Abramovitch, Ph.D. Psychology (Neuropsychology)
Associate Professor
Texas State UniversityClinical Psychology,Neuropsychology,Neuroscience,Psychopathology
Dr. Amitai Abramovitch is an Assistant Professor at the Department of Psychology at Texas State University. Dr. Abramovitch is a Licensed Clinical Psychologist and received his MA degree in Clinical Neuropsychology from the Academic College of Tel-Aviv University and obtained his Ph.D. in Psychology from Tel-Aviv. He has extensive clinical experience in individual and couple psychotherapy, parent training, and neuropsychological assessments, both from his work in national centers, hospitals, and private practice.
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Chang's work focuses on the therapy resistance of cancer stem cells, which has led to several publications and international presentations. Her clinical research aims to evaluate novel biologic agents in breast cancer patients. Chang has worked in the field of tumor-initiating cells for more than 10 years. After her discovery that tumor-initiating cells are chemo-resistant, and that targeting the EGFR/HER2 pathway can decrease this subpopulation, Chang played a key role in demonstrating some of the limitations and mechanisms of tumor-initiating cells. Her work is now focused on the mechanisms that regulate TICs, as well as initiating and planning clinical trials that target this critical tumor initiating subpopulation. She is also interested in characterizing the cross-talk between these different pathways that may lead to mechanisms of resistance, and has identified some of the chief regulatory pathways involved in TIC self-renewal. She is a world-renown clinical investigator, credited as one of the first to describe intrinsic chemo-resistance of tumor-initiating cells.
Environment,Geography,Human,Relations,Social Movement
Bone Marrow,Cancer,Oncology,Stem Cell,Transplantation
Dr. Mielcarek believes that individualizing treatment according to the patient's needs and philosophy, combined with incorporating up-to-date research knowledge, are key ingredients for excellent patient care.
Clinical Expertise
Blood stem cell and bone marrow transplantation for hematologic malignancies
Graft-versus-Host Disease (GVHD)
Title
Medical Director, Adult Blood and Marrow Transplant Program, Seattle Cancer Care Alliance
Member, Clinical Research Division, Fred Hutch
Professor of Medicine, Department of Medical Oncology, University of Washington
Education and Training
MD: Freie Universität Berlin, 1986
PhD: Freie Universität Berlin, 1987
Residency: Freie Universität Berlin, Internal Medicine, 1987-1993
Research Fellowship: Fred Hutchinson Cancer Research Center, 1994-1999
Residency: University of Washington, Internal Medicine, 1999-2000
Fellowship: University of Washington, Medical Oncology, 2000-2003
Depression,Depression and COVID,Depression in men,Psychology,Psychotherapy
Dr. Fredric Rabinowitz is a professor of psychology and associate dean at the University of Redlands and psychotherapist who specializes in working with men. He is a nationally recognized expert on the study of men and masculinity, and depression in men. Dr. Rabinowitz is one of the key architects and authors of the American Psychological Association's recently released, first-ever "2018 Guidelines for Psychological Practice with Boys and Men," a project of which he has been the steward since 2005. He is currently working on a book and has authored many articles and book chapters.
Artificial Intelligence,Big Data,Internet,Machine Learning,Semantic Web,technology policy
James Hendler is the Director of the Future of Computing Institute; Tetherless World Professor of Computer, Web and Cognitive Sciences; and Director of the RPI-IBM Artificial Intelligence Research Collaboration. Hendler is a data scientist with specific interests in open government and scientific data, data science for healthcare, AI and machine learning, semantic data integration, and the use of data in government. One of the originators of the Semantic Web, he has authored over 450 books, technical papers, and articles in the areas of Open Data, the Semantic Web, artificial intelligence, and data policy and governance. He is also the former Chief Scientist of the Information Systems Office at the US Defense Advanced Research Projects Agency (DARPA) and was awarded a US Air Force Exceptional Civilian Service Medal in 2002. He is the first computer scientist ever to have served on the Board of Reviewing editors for Science. In 2010, Hendler was selected as an “Internet Web Expert” by the US government and helped in the development and launch of the US data.gov open data website. In 2013, he was appointed as the Open Data Advisor to New York State and in 2015 appointed a member of the US Homeland Security Science and Technology Advisory Committee. In 2016, became a member of the National Academies Board on Research Data and Information, in 2017 a member of the Director’s Advisory Committee of the National Security Directorate of PNNL, and in 2021 became chair of the ACM’s global Technology Policy Council. Hendler is a Fellow of the US National Academy of Public Administration, the AAAI, AAAS, ACM, BCS and IEEE.
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