Newswise — March 21, 2023—BRONX, NY—Albert Einstein College of Medicine and Montefiore Health System have received a seven-year, $30 million grant from the National Institutes of Health (NIH) to continue support for the Harold and Muriel Block Institute for Clinical and Translational Research at Einstein and Montefiore (ICTR). The latest Clinical and Translational Science Award (CTSA) will ensure the ICTR will further its vision to improve health in the Bronx, Westchester, and lower Hudson Valley by accelerating the translation of scientific discoveries into effective and equitable prevention and treatment approaches.

“Since establishing the ICTR in 2008, our goal has been to reduce barriers that researchers face in making new discoveries and to speed the rate that scientific findings are incorporated into clinical practice,” said Marla Keller, M.D., principal investigator of the CTSA grant, director of the ICTR, and professor and vice chair of medicine at Einstein and Montefiore. “And while we have always prioritized addressing health disparities, we are launching new resources to catalyze and support research that will significantly advance health equity.”

The new CTSA award will also focus on advancing translational science, a new field of investigation dedicated to enhancing the efficiency and effectiveness of all translational research. “Over the coming years, our ICTR will introduce innovations in critical areas such as community engagement, health informatics, and data science that will facilitate research across a range of diseases and conditions,” said Mimi Kim, Sc.D., co-principal investigator of the CTSA grant, associate director of the ICTR, and professor and head of the division of biostatistics in the department of epidemiology & population health at Einstein and Montefiore.

Over the past 15 years, the ICTR has supported approximately 1,000 projects each year, many to address diseases that are disproportionately prevalent in the Bronx, including diabetes, opioid use disorder, HIV, cardiovascular disease, cancer, and asthma. The ICTR played a leading role in Montefiore and Einstein’s response to the COVID-19 pandemic, including participation in 15 multicenter clinical trials, publication of “real-world” studies on people with both COVID-19 and another disease or condition, identification of immune responses in children, and assistance in developing national treatment guidelines.

The ICTR will also continue to innovate approaches to research around structural racism and its impact on health. The institute has previously supported initiatives that directly advance health equity, such as Montefiore’s roll-out of social needs screenings to better understand the challenges patients face at both the individual and population levels. The new grant will expand these efforts, assisting investigators to integrate social needs into study design, use new tools and algorithms to evaluate overlapping social needs, and understand systems-level bias and discrimination.

"At the core of Einstein and Montefiore has always been a commitment to equitable access to healthcare, education, and research for all people in our communities," said Paul Marantz, M.D., M.P.H., associate dean for clinical research education at Einstein, associate director of the ICTR, and professor of epidemiology and population health and of medicine at Einstein and Montefiore.

Consistent with the ICTR’s theme of “Building Bridges in the Bronx and Beyond, an expanded ICTR community and stakeholder engagement core co-directed by Carmen Isasi, M.D., Ph.D., and Earle Chambers, Ph.D., M.P.H., will develop new models of community engagement to foster deeper connections with members of the Bronx, Westchester, and lower Hudson Valley communities so their perspectives can better inform research topics and priorities. The ICTR will expand its partnerships with community-based organizations to generate and disseminate study results and evidence-based health information to local residents.

The grant, titled “Einstein-Montefiore Clinical and Translational Science Award Hub,” was provided by the National Center for Advancing Translational Sciences (NCATS), part of the NIH (1UM1TR004400). The ICTR at Einstein and Montefiore is one of more than 60 institutions supported by the CTSA Program at NCATS.

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 About Albert Einstein College of Medicine 
Albert Einstein College of Medicine is one of the nation’s premier centers for research, medical education and clinical investigation. During the 2022-23 academic year, Einstein is home to 740 M.D. students, 194 Ph.D. students, 118 students in the combined M.D./Ph.D. program, and approximately 225 postdoctoral research fellows. The College of Medicine has more than 1,900 full-time faculty members located on the main campus and at its clinical affiliates. In 2022, Einstein received more than $202 million in awards from the National Institutes of Health. This includes the funding of major research centers at Einstein in cancer, aging, intellectual development disorders, diabetes, clinical and translational research, liver disease, and AIDS. Other areas where the College of Medicine is concentrating its efforts include developmental brain research, neuroscience, cardiac disease, and initiatives to reduce and eliminate ethnic and racial health disparities. Its partnership with Montefiore, the University Hospital and academic medical center for Einstein, advances clinical and translational research to accelerate the pace at which new discoveries become the treatments and therapies that benefit patients. For more information, please visit einsteinmed.edu, follow us on Twitter, Facebook, Instagram, LinkedIn, and view us on YouTube

About Montefiore Health System
Montefiore Health System is one of New York’s premier academic health systems and is a recognized leader in providing exceptional quality and personalized, accountable care to approximately three million people in communities across the Bronx, Westchester and the Hudson Valley. It is comprised of 10 hospitals, including the Children’s Hospital at Montefiore, Burke Rehabilitation Hospital and more than 200 outpatient ambulatory care sites. The advanced clinical and translational research at its medical school, Albert Einstein College of Medicine, directly informs patient care and improves outcomes. From the Montefiore-Einstein Centers of Excellence in cancer, cardiology and vascular care, pediatrics, and transplantation, to its preeminent school-based health program, Montefiore is a fully integrated healthcare delivery system providing coordinated, comprehensive care to patients and their families. For more information, please visit www.montefiore.org. Follow us on Twitter and Instagram and LinkedIn, or view us on Facebook and YouTube.

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CITATIONS

1UM1TR004400