Co-option of endogenous retroviruses through genetic escape from TRIM28 repression
PreprintsEndogenous retroviruses (ERVs) have rewired host gene networks through co-option of their enhancers.
Endogenous retroviruses (ERVs) have rewired host gene networks through co-option of their enhancers.
TANGO2-deficient disorder (TDD) is an autosomal recessive genetic disease caused by biallelic loss-of-function variants in TANGO2 gene.
RNA-binding proteins (RBPs) are pivotal for regulating gene expression as they are involved in each step of RNA metabolism.
Cancer cells can have thousands of mutations in their DNA. However, only a handful of those actually drive the progression of cancer; the rest are just along for the ride.
DETROIT (June 20, 2022) – As robotic surgical systems continue to evolve and assist surgeons with improving surgical precision, a Henry Ford Health study found that robotic-assisted surgery for hip replacement had lower rates of complications than the traditional method. The findings, published in The Journal of Arthroplasty, are believed to be the first from a large series of patients with several years of follow-up to evaluate post-surgical complications between the two surgical options, adding to the growing body of research in the hip replacement field.
Matteo Togninalli, Andrew T.V. Ho, Christopher M Madl, Colin A. Holbrook, Yu Xin Wang, Klas E.G. Magnusson, Anna Kirillova, Andrew Chang, Helen Blau
Researchers at Ruhr-Universität Bochum have been studying the role of the two proteins tenascin C and tenascin R in multiple sclerosis. In this disease, cells of the immune system destroy the myelin sheaths, i.e. the sheaths of the nerve cells.
New wearable technology creates new possibilities for assessing the neurological development of young children. Early motor assessment is essential for supporting the early detection of neurodevelopmental problems and their therapeutic interventions.
Fabiana Faleiros, Deyse Braga, Soraia Dornelles Schoeller, Sílvia Helena Henriques, Naira Beatriz Favoretto Cunha, Lorena Gomes Neves Videira, Adriana Cordeiro Leandro Silva Grillo
Daniel Levy, Anjana Jeyaram, Louis J Born, Kai-Hua Chang, Sanaz Nourmohammadi Abadchi, Angela Ting Wei Hsu, Talia Solomon, Amaya Aranda, Samantha Stewart, XiaoMing He, John W Harmon, Steven M Jay
Donna L McPhie, Boyu Ren, Juan Antonio Garcıa-Leon, Catherine M Verfaillie, Bruce M Cohen
Keisuke Kozai, Ayelen Moreno Irusta, Khursheed Iqbal, Mae-Lan Winchester, Regan L Scott, Mikaela E Simon, Masanaga Muto, Marc R Parrish, Michael J Soares
Yongkang Yang, David Z. Chen, Sergio Rey, Jun O. Liu, Gregg L. Semenza
Mehmet Kural, Umidahan Djakbarova, Bilal Cakir, Yoshiaki Tanaka, Yasaman Madraki, Hong Qian, Jinkyu Park, Lorenzo Sewanan, Comert Kural, Laura Niklason
Erik Jacques, Yinni Kuang, Allison P Kann, Robert S Krauss, Penney M Gilbert
Nicholas Daniel Henkel, Alex Joyce, Elizabeth Shedroff, Ali Sajid Imami, Khaled Alganem, Abdul-Rizaq Hamoud, Chongchong Xu, Benjamin Siciliano, Tao Ma, Zhexing Wen, Robert Erne McCullumsmith
Hisao Masai, Youichi Tajima, Futoshi Shibazaki
Zhiqiang Wang, Leilei Li, Wanpu Wang, Lilin Luo, Shuai Dong, Menglong Li, Tianxing Chen, Qingyang Meng, Rui Liang
Evdokiia Potolitsyna, Sarah Hazell Pickering, Ave Tooming-Klunderud, Philippe Collas, Nolwenn Briand
Marija Kuna, Pramod Dhakal, Khursheed Iqbal, Esteban M. Dominguez, Lindsey N. Kent, Masanaga Muto, Ayelen Moreno-Irusta, Keisuke Kozai, Kaela M. Varberg, Hiroaki Okae, Takahiro Arima, Henry M. Sucov, Michael J. Soares
Researchers have developed a unique 3D printed system for harvesting stem cells from bioreactors, offering the potential for high quality, wide-scale production of stem cells in Australia at a lower cost.
Julianne N.P. Smith, Brittany A Cordova, Brian Richardson, Kelsey F Christo, Jordan Campanelli, Alyssia V Broncano, Jonathan Chen, Juyeun Lee, Scott J Cameron, Justin D Lathia, Wendy A Goodman, Mark J Cameron, Amar B Desai
Jéssica Rodrigues Orlandin, Sarah Ingrid Pinto Santos, Luciana Cristina Machado, Paulo Fantinato Neto, Fabiana Fernandes Bressan, Naira Caroline Godoy Pieri, Kaiana Recchia, Meline de Paula Coutinho, Priscilla Avelino Ferreira Pinto, Annalisa Santucci, Valter Travagli, Carlos Eduardo Ambrosio
Lingli Gong, Ying Yin, Cheng Chen, Quan Wan, Die Xia, Mei Wang, Zhening Pu, Bo Zhang, Jian Zou
Norbert Blank, Marc Schmalzing, Pia Moinzadeh, Max Oberste, Elise Siegert, Ulf Müller-Ladner, Gabriela Riemekasten, Claudia Günther, Ina Kötter, Gabriele Zeidler, Christiane Pfeiffer, Aaron Juche, Ilona Jandova, Jan Ehrchen, Laura Susok, Tim Schmeiser, Cord Sunderkoetter, Jörg H. W. Distler, Margitta Worm, Alexander Kreuter, Gernot Keyzer, Hanns-Martin Lorenz, Thomas Krieg, Nicolas Hunzelmann, Joerg Henes
Hani Jieun Kim, Michelle Ohara-Wright, Daniel Kim, To Ha Loi, Benjamin Y Lim, Robyn V Jamieson, Anai Gonzalez Cordero, Pengyi Yang
Sha Yin, Wenjin Gao, Ye Fan, Rui Xia, Mingyue Duan, Xi Zhang, Ansheng Liu, Yanmin Zhang
Gregory W Roloff, Reid Shaw, Timothy E O'Connor, Michael W Drazer
Sangeeta Ghuwalewala, Kevin Jiang, Sara Ragi, David Shalloway, Tudorita Tumbar
Parisa Kangari, Leila Roshangar, Aida Iraji, Tahereh Talaei-Khozani, Mahboobeh Razmkhah
Biomedicines are produced by living cells and are used to treat cancer and autoimmune diseases among other things.
A drug carrier able to reach the brain, bind to an aggressive type of tumor called glioblastoma multiforme, and release a chemotherapeutic agent has been tested for the first time by Brazilian researchers.
If you’ve ever swallowed the same round tablet in hopes of curing everything from stomach cramps to headaches, you already know that medicines aren’t always designed to treat precise pain points.
As we age, so do our eyes; most commonly, this involves changes to our vision and new glasses, but there are more severe forms of age-related eye problems. One of these is age-related macular degeneration, which affects the macula — the back part of the eye that gives us sharp vision and the ability to distinguish details.
Researchers from Wake Forest University School of Medicine have discovered a possible new approach in treating solid tumors through the creation of a novel nanoparticle.
Terry Hermiston, Jonathan Hardy, Maxine Bauzon, Francis G Blankenberg, Masamitsu Kanada, Ashley Makela, Charles K. F. Chan, Christopher H Contag
Pei Xu, Lei Wang, Qingtao Liu, Pengkai Gao, Fengqing Hu, Xiao Xie, Lianyong Jiang, Rui Bi, Fangbao Ding, Qi Yang, Haibo Xiao
Xin Zhao, Changjun Chen, Yue Luo, Donghai Li, Qiuru Wang, Yuying Fang, Pengde Kang
Daniel Cebo
James A. Watson, Raphaël Pantier, Uma Jayachandran, Kashyap Chhatbar, Beatrice Alexander-Howden, Valdeko Kruusvee, Michal Prendecki, Adrian P Bird, Atlanta G. Cook
Soghra Bahmanpour, Zia Moasses, Nehleh Zareifard
The Pew Charitable Trusts has named Maayan Levy, PhD, an assistant professor of Microbiology at the Perelman School of Medicine at University of Pennsylvania, a 2022 Pew Scholar in the Biomedical Sciences. The Pew Charitable Trusts and the Alexander and Margaret Stewart Trust have also selected Alexander Huang, MD, an assistant professor of Hematology-Oncology, and Chengcheng Jin, PhD, an assistant professor of Cancer Biology, as 2022 Pew-Stewart Scholars for Cancer Research. John James Tello Cajiao, PhD, a postdoctoral fellow in Pathology & Laboratory Medicine, has been named a 2022 Pew Latin American Fellow in the Biomedical Sciences.
Researchers at Karolinska Institutet in Sweden show how a molecule that they have identified stimulates the formation of new insulin-producing cells in zebrafish and mammalian tissue, through a newly described mechanism for regulating protein synthesis.
As you’re reading this sentence, the cells in your brain, called neurons, are sending rapid-fire electrical signals between each other, transmitting information.
Thomas L Li, Yuxin Liu, Csaba Forro, Levent Beker, Zhenan Bao, Bianxiao Cui, Sergiu P Pasca
Ying Wang, Keda Chen, Xiaolong Lin
Khadar Abdi, Ramona Rodriguez, William C Wetsel, Michelle E Arlotto, Robert W McGarrah, Phillip J White
Min-Jeong Kang, Nuri Jin, Shin-Young Park, Joong-Soo Han
Yechiel Elkabetz, Sneha Arora, Anastasios Balaskas, Amèlia Aragonés Hernández, Daniel Rosebrock
Ken-Ichi Kudo, Naohiro Tsuyama, Kento Nagata, Tatsuhiko Imaoka, Daisuke Iizuka, Misaki Sugai-Takahashi, Moe Muramatsu, Akira Sakai