Feature Channels: Biotech

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Released: 26-Sep-2022 12:00 PM EDT
Aging and Obesity Prime the Methylome and Transcriptome of Adipose Stem Cells for Disease and Dysfunction
Preprints

Shaojun Xie, Sulbha Choudhari, Chia-Lung Wu, Karen Abramson, David Corcoran, Simon G Gregory, Jyothi M Thimmapuram, Farshid Guilak, Dianne Little

Released: 26-Sep-2022 12:00 PM EDT
Improving stem cell-derived pancreatic islets using single-cell multiome-inferred regulomes
Preprints

Han Zhu, Gaowei Wang, Kim-Vy Nguyen-Ngoc, Dongsu Kim, Michael Miller, Georgina Goss, Jenna Kovsky, Austin R Harrington, Diane Saunders, Rebecca Melton, Alvin C Powers, Sebastian Preissl, Francesca M Spagnoli, Kyle J Gaulton,

Released: 25-Sep-2022 12:00 PM EDT
Enhancing Sox/Oct cooperativity induces higher-grade developmental reset
Preprints

Caitlin M. MacCarthy, Vikas Malik, Guangming Wu, Taras Velychko, Gal Keshet, Ralf Jauch, Vlad Cojocaru, Hans Scholer, Sergiy Velychko

Released: 24-Sep-2022 12:00 PM EDT
LINC01137 facilitate pancreatic cancer stemness via the miR-7155-5p/KLF12/AKT axis
Preprints

Kexian Li, Zengyu Feng, Kai Qin, Yang Ma, Shiwei Zhao, Peng Chen, Jiewei Lin, Yongsheng Jiang, Lijie Han, Yizhi Cao, Jiaxin Luo, Minmin Shi, Hao Chen, Jiancheng Wang, Lingxi

Released: 23-Sep-2022 2:05 PM EDT
Rutgers Researchers Aim to 'Edit' Proteins in Humans and Attain Insight into Illness
Rutgers University-New Brunswick

Rutgers researchers are seeking to develop the technology to modify or “edit” protein molecules in the body—an advance that could spur major breakthroughs in human health.

   
Released: 23-Sep-2022 12:00 PM EDT
IRF7 impacts on prostate cancer cell survival in response to radiation
Preprints

Adam Pickard, Francesca Amoroso, Kelsey McCulloch, Andrew Erickson, Ashwin Sachdeva, Rebecca Steele, Debayan Mukherjee, Margaret Dellett, Jonathan McComb, Laura McCaffrey, Claire Hart, Michael Brown, Simon S McDade, David Waugh,

Released: 23-Sep-2022 12:00 PM EDT
Efficacy and safety of synbiotics in patients undergoing autologous hematopoietic stem cell transplantation: A prospective, randomized, double-blind, placebo-controlled pilot study
Preprints

Yu Mizutani, Shinichiro Kawamoto, Michiko Takahashi, Hisayo Doi, Kumiko Wakida, Satoko Tabuchi, Masaaki Tanda, Akihiro Soga, Ruri Chijiki, Hidetomo Takakura, Koji Kawaguchi, Ako Higashime, Marika Watanabe, Hiroya Ichikawa,

Released: 23-Sep-2022 12:00 PM EDT
Breast Cancer With Increased Drug Resistance, Invasion Ability, and Cancer Stem Cell Property Through Metabolism Reprogramming
Preprints

Kian-Hwee Chong, Yao-Jen Chang, Wei-Hsin Hsu, Ya-Ting Tu, Yi-Ru Chen, Ming-Cheng Lee, Kuo-Wang Tsai

Released: 23-Sep-2022 12:00 PM EDT
Germ-stem cells and oocyte production in the Honeybee Queen Ovary
Preprints

Georgia Cullen, Joshua B Gilligan, Joseph G Guhlin, Peter K Dearden

Released: 23-Sep-2022 12:00 PM EDT
Requirement for STAT3 and its target, TFCP2L1 in self-renewal of naïve pluripotent stem cells in vivo and in vitro
Preprints

Sophie Louise Kraunsoe, Takuya Azami, Yihan Pei, Graziano Martello, Kenneth Alan Jones, Thorsten Edwin Boroviak, Jennifer Nichols

Released: 22-Sep-2022 12:00 PM EDT
ESDR573 - Marine and Bovine-Derived Collagen Peptides Inhibit Catagen Development and Generate Diverse Effects on Stem Cells and Progeny in Human Scalp Hair Follicles Ex Vivo
Preprints

Karin Pappelbaum, Nicolina Virgilio, Francisco Jiménez, Wolfgang Funk, Janne Prawitt, Bastian van der Steen, Marta Bertolini

Released: 22-Sep-2022 12:00 PM EDT
The impact of pretransplant use of tyrosine kinase inhibitors on allogeneic stem cell transplantation in patients with chronic myeloid leukemia - A single-institution retrospective study
Preprints

Shinya Fujita, Masatoshi Sakurai, Hidenori Kasahara, Jun Kato, Yuya Koda, Kentaro Yamaguchi, Kohei Shiroshita, Mikio Okayama, Ryohei Abe, Taku Kikuchi, Takayuki Shimizu, Takehiko Mori, Keisuke Kataoka, Shinichiro Okamoto

Released: 22-Sep-2022 12:00 PM EDT
Three-dimensional nanofibrous sponges with aligned architecture and controlled hierarchy regulating neural stem cell fate for spinal cord regeneration
Preprints

Shilei Ni, Zhiwei Li, Ye Qi, Lei Sun, Zheng Li, Shaojun Chen, Yuqi Zhang, Yuan Ma, Jinming Han, Zide Wang, Yulin Zhang, Huimin Geng, Bin Huang, Jian Wang, Gang Li,

Released: 22-Sep-2022 12:00 PM EDT
ESDR572 - Olfactory Receptor 2A4/7 Activation by the Fragrance, Cyclohexyl Salicylate, Promotes Human Hair Follicle Growth and Stem Cell Progeny Expansion
Preprints

Janin Edelkamp, Daniela Pinto, Hanieh Erdmann, Talveen Purba, Francisco Jiménez, Ralf Paus, Marta Bertolini

Released: 22-Sep-2022 12:00 PM EDT
ESDR559 - Induction of tissue-specific premature stem cell aging promotes senescence-like phenotypes in remote multiple organs
Preprints

Yasuaki Ikuno, Koichiro Watanabe, Yumi Kakeya, Toshimasa Nakabo, Dai Ihara, Noriki Fujimoto, Hayato Naka-Kaneda

Released: 22-Sep-2022 12:00 PM EDT
Carcinoma associated mesenchymal stem cells promote ovarian cancer metastasis by increasing tumor heterogeneity through direct mitochondrial transfer
Preprints

Catherine Pressimone, Leonard G Frisbie, Emma Dyer, Roja Baruwal, Grace Gorecki, Zaineb Javed, Claudette St. Croix, Simon C Watkins, Michael Calderon, Huda I Atiua, Nadine Hempel, Alexander T. Pearson, Lan Coffman

Released: 22-Sep-2022 12:00 PM EDT
The relationship between PD-L1 and quiescence in melanocyte stem cell aging.
Preprints

Joseph W. Palmer, Kyrene M. Villavicencio, Misgana Idris, Dominique Weddle, Fabian V. Filipp, William J. Pavan, Melissa L. Harris, Nisc Comparative Sequencing Program - Nhgri

Released: 21-Sep-2022 12:00 PM EDT
The effects of adipose-derived stem cell transplantation on tendon-bone healing in a model of chronic rotator cuff tear with suprascapular nerve injury
Preprints

Kenichiro Eshima, Hiroki Ohzono, Masafumi Gotoh, Hidehiro Nakamura, Takahiro Okawa, Naoto Shiba

Released: 21-Sep-2022 12:00 PM EDT
ESDR556 - Functional and proliferative melanocyte-derived pluripotent stem cells: from developmental studies to clinical perspectives
Preprints

Manoubia Saidani, Annabelle Darle, Margot Jarrige, Hélène Polveche, Sévenine Julie, Sandrine Bessou Touya, Lemaitre Gilles, Cécile Martinat, Christine Baldeschi, Jennifer Allouche

Released: 21-Sep-2022 12:00 PM EDT
Genome instability underlies an augmented DNA damage response in familial and sporadic ALS human iPSC-derived motor neurons
Preprints

Oliver Ziff, Jacob Neeves, Jamie Mitchell, Guilia Tyzack, Carlos Ruiz, Nicholas McGranahan, Raphaelle Luisier, Anob Chakrabarti, Simon Boulton, Gavin Kelly, Jack Humphrey, Rickie Patani

Released: 21-Sep-2022 12:00 PM EDT
A bipartite function of ESRRB can integrate signaling over time to balance self-renewal and differentiation
Preprints

Teresa Emmilie Knudsen, William Hamilton, Martin Proks, Maria Lykkegaard, Alexander Valentin Nielsen, Ala Trusina, Joshua M Brickman

Released: 20-Sep-2022 12:00 PM EDT
Presence of cells in the polyaneuploid cancer cell (PACC) state predicts risk of recurrence in prostate cancer
Preprints

Levent Trabzonlu, Kenneth J Pienta, Bruce J Trock, Angelo Michael De Marzo, Sarah R Amend

Released: 20-Sep-2022 12:00 PM EDT
Autophagy inhibits inflammation via down-regulation of p38 MAPK/mTOR signaling cascade in endothelial cells
Preprints

Ling Zhou, Juanjuan Wang, Hui Hou, Jiao Li, Juan Li, Jiannan Liang, Junqin Li, Xuping Niu, Ruixia Hou, Kai-Ming Zhang

Released: 20-Sep-2022 12:00 PM EDT
Integrated analysis of next generation sequencing minimal residual disease (MRD) and PET scan in transplant eligible myeloma patients
Preprints

Rodrigo Fonseca, Mariano Arribas, Julia E. Wiedmeier-Nutor, Yael N. Kusne, Miguel Gonzalez-Velez, Heidi Kosiorek, Richard J. Butterfield, Ilan Kirsch, Joseph Mikhael, A. Keith Stewart, Craig Reeder, Jeremy Larsen, P. Bergsagel, Rafael Fonseca

Released: 20-Sep-2022 12:00 PM EDT
mRNA-based generation of marmoset PGCLCs capable of differentiation into gonocyte-like cells
Preprints

Musashi Kubiura-Ichimaru, Christopher Penfold, Kazuaki Kojima, Constance Dollet, Haruka Yabukami, Katsunori Semi, Yasuhiro Takashima, Thorsten Boroviak, Hideya Kawaji, Knut Woltjen, Aki Minoda, Erika Sasaki, Toshiaki Watanabe

Released: 20-Sep-2022 12:00 PM EDT
Intensity of Induction Regimen and Outcomes Among Adults with Ph+ ALL Undergoing Allogeneic Hematopoietic Stem Cell Transplantation
Preprints

Marlise Luskin, Hari Raman, Se Eun Kim, Daniel DeAngelo, Kristen Stevenson, Donna Neuberg, Eric Winer, Martha Wadleigh, Jacqueline Garcia, Annette Kim, Richard Stone, Vincent Ho

Released: 20-Sep-2022 12:00 PM EDT
Differential elasticity in lineage segregation of embryonic stem cells
Preprints

Christine M. Ritter, Natascha Leijnse, Younes Farhangi Barooji, Joshua M. Brickman, Amin Doostmohammadi, Lene B. Oddershede

Released: 19-Sep-2022 12:00 PM EDT
Inositol pyrophosphate profiling reveals regulatory roles of IP6K2-dependent enhanced IP7 metabolism in enteric nervous system
Preprints

Masatoshi Ito, Natsuko Fujii, Saori Kohara, Shuho Hori, Masayuki Tanaka, Christopher Wittwer, Kenta Kikuchi, Takatoshi Iijima, Yu Kakimoto, Kenichi Hirabayashi, Daisuke Kurotaki, Henning Jacob Jessen, Adolfo Saiardi, Eiichiro Nagata

Released: 19-Sep-2022 12:00 PM EDT
Lung remodeling regions in long-term Covid-19 feature basal epithelial cell reprogramming
Preprints

Kangyun Wu, Yong Zhang, Stephen R Austin, Huqing Yin Declue, Derek E Byers, Erika C Crouch, Michael J Holtzman

Released: 19-Sep-2022 12:00 PM EDT
Weight Loss Post Allogeneic Stem Cell Transplant is Associated with Increased Transplant Related Mortality
Preprints

Kayla Madsen, Katherine Lee, Shiyi Chen, Carol Chen, Arjun Law, Armin Gerbitz, Rajat Kumar, Dennis Kim, Wilson Lam, Ivan Pasic, Auro Viswabandya, Fotios Michelis, Ram Vasudevan Nampoothiri, Jeffrey Lipton,

Newswise: University of Oklahoma Biomedical Engineering Researcher Ready to Transform TBI Surgery
Released: 19-Sep-2022 11:05 AM EDT
University of Oklahoma Biomedical Engineering Researcher Ready to Transform TBI Surgery
University of Oklahoma, Gallogly College of Engineering

Patients who suffer a severe traumatic brain injury must undergo two surgeries: one to remove a part of the skull to allow the brain to swell and another surgery to replace the missing bone after brain swelling subsides. University of Oklahoma biomedical engineering researcher Michael Detamore and his team may have found a way to reduce the number of surgeries to just one.

Released: 18-Sep-2022 12:00 PM EDT
Reserpine maintains photoreceptor survival in retinal ciliopathy by resolving proteostasis imbalance and ciliogenesis defects
Preprints

Holly Y Chen, Manju Swaroop, Samantha Papal, Anupam Mondal, Gregory Tawa, Florian Regent, Hiroko Shimada, Kunio Nagashima, Natalia de Val, Samuel G Jacobson, Wei Zheng, Anand Swaroop

Released: 18-Sep-2022 12:00 PM EDT
Within-host virus evolution during the extended treatment of RSV infection with mutagenic drugs
Preprints

Christopher Jr Illingworth, Alexandra Y Kreins, Adriana Margarit Soler, Tim Best, Patricia Dyal, Giovanna Lucchini, Kanchan Rao, Rachel Williams, Austen Jj Worth, Judith Breuer



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