Curated News: Cell (journal)

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Released: 7-Apr-2020 12:20 PM EDT
Common Protein in Skin Can ‘Turn On’ Allergic Itch
North Carolina State University

A commonly expressed protein in skin – periostin – can directly activate itch-associated neurons in the skin. Blocking periostin receptors on these neurons reduced the itch response in a mouse model of atopic dermatitis, or eczema.

Newswise: 228393_web.jpg
Released: 3-Apr-2020 2:25 PM EDT
Trial drug can significantly block early stages of COVID-19 in engineered human tissues
University of British Columbia

An international team led by University of British Columbia researcher Dr. Josef Penninger has found a trial drug that effectively blocks the cellular door SARS-CoV-2 uses to infect its hosts.

Newswise: 227628_web.jpg
Released: 30-Mar-2020 5:30 PM EDT
Nafamostat is expected to prevent the transmission of new coronavirus infection (COVID-19)
University of Tokyo

Nafamostat mesylate (brand name: Fusan), which is the drug used to treat acute pancreatitis, may effectively block the requisite viral entry process the new coronavirus (SARS-CoV-2) uses to spread and cause disease (COVID-19). The University of Tokyo announced these new findings on March 18, 2020.

Newswise: Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
24-Mar-2020 4:20 PM EDT
Deleting a gene prevents Type 1 diabetes in mice by disguising insulin-producing cells
University of Wisconsin-Madison

Removing a gene from the cells that produce insulin prevents mice from developing Type 1 diabetes by sparing the cells an attack from their own immune system, a new UW–Madison study shows.

Newswise: How Sperm Unpack Dad’s Genome so it Can Merge with Mom’s
Released: 13-Mar-2020 2:20 PM EDT
How Sperm Unpack Dad’s Genome so it Can Merge with Mom’s
University of California San Diego Health

UC San Diego researchers discover the enzyme SPRK1’s role in reorganizing the paternal genome during the first moments of fertilization — a finding that might help explain infertility cases of unknown cause.

Newswise: Molds damage the lung’s protective barrier to spur future asthma attacks
Released: 12-Mar-2020 3:40 PM EDT
Molds damage the lung’s protective barrier to spur future asthma attacks
University of Wisconsin-Madison

University of Wisconsin–Madison researchers have identified a new way that common Aspergillus molds can induce asthma, by first attacking the protective tissue barrier deep in the lungs.

Released: 10-Mar-2020 11:30 AM EDT
Muscle stem cells compiled in ‘atlas’
Cornell University

A team of Cornell researchers led by Ben Cosgrove, assistant professor in the Meinig School of Biomedical Engineering, used a new cellular profiling technology to probe and catalog the activity of almost every kind of cell involved in muscle repair. They compiled their findings into a “cell atlas” of muscle regeneration that is one of the largest datasets of its kind.

Released: 6-Mar-2020 2:00 PM EST
Study: Cough That Spreads Tuberculosis Has Pain-Linked Trigger
University of Texas at Dallas

University of Texas System researchers have pinpointed a molecule that the tuberculosis bacterium manufactures to induce the coughing that spreads the disease by triggering a pain-receptor response. Their findings illustrate that the disease's spread might be prevented by halting production of sulfolipid-1.

4-Mar-2020 4:40 PM EST
Researchers Discover a New Diet-Associated Gut-Microbe Metabolite Linked to Cardiovascular Disease
Cleveland Clinic

Cleveland Clinic researchers have identified a gut microbe generated byproduct – phenylacetylglutamine (PAG) – that is linked to development of cardiovascular disease, including heart attack, stroke and death. The study was published in Cell today.

Released: 3-Mar-2020 11:30 AM EST
Presence of Staph Bacteria in Skin Microbiome Promotes Netherton Syndrome Inflammation
University of California San Diego Health

Netherton syndrome is exacerbated by the presence of Staphylococcus aureus and Staphylococcus epidermidis living on human skin report University of California San Diego School of Medicine researchers.


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