Oncologists can use colorectal cancer patients’ own immune system to boost the effects of chemotherapy and increase progression-free survival, according to Phase III study results presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Breast cancer survivors with poor physical health scores had an elevated risk of poorer cancer outcomes, including recurrence and death, according to the results of an observational study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Freeze-dried strawberries may be an alternative to drugs for the prevention of esophageal cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Experts from The Cancer Institute at NYU Langone Medical Center presented new research findings at the American Association for Cancer Research 102nd Annual Meeting 2011 held April 2-6, 2011 in Orlando, Florida. NYU Cancer Institute researchers discussed various breakthroughs such as a novel test for early-stage asbestos-related pulmonary cancer, a promising treatment strategy for glioblastomas, genome-wide mapping of nickel-related cancer and greater understanding of melanoma and bladder cancer.
While there is an increasing equality in terms of the likelihood that children from communities and families across the socioeconomic spectrum will be diagnosed with autism, a new study finds that such factors still influence the chance of an autism diagnosis, though to a much lesser extent than they did at the height of rising prevalence.
Modifying a protein from a plant much favored by science, researchers at the University of California, San Diego School of Medicine and colleagues have created a new type of genetic tag visible under an electron microscope, illuminating life in never-before-seen detail.
Meditation produces powerful pain-relieving effects in the brain, according to new research published in the April 6 edition of the Journal of Neuroscience.
Investigators have attempted to replicate 2009 findings that associated the XMRV retrovirus with Chronic Fatigue Syndrome. However those studies have been performed on blood. The current study focuses instead on cerebrospinal fluid, given the syndrome's impact on nervous system function.
Among postmenopausal women with prior hysterectomy who had used estrogen therapy for about 6 years and then stopped, longer-term follow-up indicates that the increased risk of stroke seen during the intervention period had dissipated, the decreased risk of hip fracture was not maintained, while the decreased risk of breast cancer persisted, according to a study in the April 6 issue of JAMA.
Higher levels in blood of the protein clusterin, also known as apolipoprotein J, are significantly associated with the prevalence and severity of Alzheimer's disease, but not with the risk of onset of new disease, according to a study in the April 6 issue of JAMA.
In an analysis of opioid prescription patterns and deaths, receiving higher prescribed doses is associated with an increased risk of opioid overdose death, but receiving both as-needed and regularly scheduled doses is not associated with overdose risk, according to a study in the April 6 issue of JAMA.
An analysis of data from 10 studies indicates that the presence of low frequency (also called "minority") human immunodeficiency virus type 1 (HIV-1) drug resistance mutations, particularly those involving nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance, are significantly associated with an increased risk of first-line antiretroviral treatment failure, according to an article in the April 6 issue of JAMA.
An editorial in the April 6 issue of the Journal of the American Medical Association cautions against estrogen-only hormone therapy in women who have had a hysterectomy because of longstanding evidence that it raises the risk of breast cancer.
Soy food consumption did not increase the risk of cancer recurrence or death among survivors of breast cancer, according to the results of a study presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Research from New Jersey’s only NCI-Comprehensive Cancer Center explores the protein HER2 and the role it plays in breast cancer aggressiveness, poor clinical outcome and chemotherapy resistance. The findings, being presented at the 102 Annual Meeting of the AACR, indicate that under stressful conditions, too much HER2 can cause a decrease in the cell-survival mechanism of autophagy. This decrease can lead to the alteration of other cellular processes and may increase breast cancer metastasis.
Researchers at the University of Pennsylvania School of Medicine may have found a way to turn an adaptive cellular response into a liability for cancer cells by treating a group of patients with several different types of advanced cancers with temsirolimus, a molecularly targeted cancer drug that blocks nutrient uptake, plus hydroxychloroquine, an anti-malarial drug that inhibits autophagy. The regimen halted tumor growth in two-thirds of the patients.
Cardiologists from the Cardiac & Vascular Institute at NYU Langone Medical Center presented new research findings at the American College of Cardiology 60th Annual Scientific Session held April 2-5, 2011 in New Orleans, Louisiana.
Breast cancer survivors who experience extreme weight gain have an increased risk of death after breast cancer diagnosis. Moderate weight gain did not affect breast cancer outcomes. These study results were presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Using minute graphite particles 1000 times smaller than the width of a human hair, mechanical engineers at Arizona State University hope to boost the efficiency—and profitability—of solar power plants.
For some people, alcohol is a social lubricant. For others, it's an unpleasant downer. New research shows that a person's response to alcohol can predict their future drinking behavior, including their frequency of binge drinking and the risk of developing an alcohol-use disorder.
Adolescent girls participating in high-impact physical activity, specifically basketball, running and gymnastics/cheerleading, appear to be at increased risk for developing stress fractures, according to a report posted online today that will appear in the August print issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
Having a significant other who exhibits controlling behaviors appears to be associated with increased physical and sexual relationship violence, according to a report in the April issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. However, young women experiencing these behaviors are more hesitant to answer questions about relationship violence.
The prevalence of plagiocephaly, a condition marked by an asymmetrical, flattening of the skull, appears to be increasing in infants and young children, according to a report posted online today that will appear in the August issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals.
Persons with an addictive-like eating behavior appear to have greater neural activity in certain regions of the brain similar to substance dependence, including elevated activation in reward circuitry in response to food cues, according to a report posted online today that will appear in the August print issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
People who migrate to the United States from Mexico have a significantly higher risk of developing depressive or anxiety disorders than family members of migrants who remain in Mexico, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Low levels of household income are associated with several lifetime mental disorders and suicide attempts, and a decrease in income is associated with a higher risk for anxiety, substance use, and mood disorders, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.
Fossil teeth of African animals show that during the past 10 million years, different plant-eating critters began grazing on grass at different times as many switched from a salad-bar diet of tree leaves and shrubs, says a University of Utah study.
Scientists from the Morgridge Institute for Research, the University of Wisconsin-Madison, the University of California and the WiCell Research Institute moved gene therapy one step closer to clinical reality by determining that the process of correcting a genetic defect does not substantially increase the number of potentially cancer-causing mutations in induced pluripotent stem cells.
A species of algae long known to associate with spotted salamanders has been discovered to live inside the cells of developing embryos, say scientists from the U.S. and Canada, who report their findings in this week's PNAS. This is the first known example of a eukaryotic algae living stably inside the cells of any vertebrate.
Vanderbilt researchers, who helped organize a consortium including the University of Pennsylvania School of Medicine, the University of Miami Miller School of Medicine, and the Boston University School of Medicine, have identified four new genes linked to Alzheimer’s disease. The findings, released today by Nature Genetics, effectively double the number of genes known to contribute to the disease, according to Jonathan Haines, Ph.D., director, Vanderbilt Center for Human Genetics Research.
Judy E. Garber, M.D., M.P.H., was inaugurated today as president of the American Association for Cancer Research at the AACR 102nd Annual Meeting 2011. This year’s meeting theme is “Innovation and Collaboration: The Path to Progress.”
Researchers at McMaster University and Hamilton Health Sciences have found accessing blocked arteries through the forearm compared to groin led to fewer vascular complications and similar success rates for angioplasty.
As cancer continues to affect one in two men and one in three women, researchers are increasing their knowledge on the known risk factors for cancer both environmentally and genetically.
Women with ovarian cancer who have the BRCA2 gene mutation are more likely to survive the malignancy than women with the BRCA1 mutation, or women without either mutation.
Among people with AIDS, the risk of stomach and esophageal malignancies is higher than among the general population, according to study results presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Heavy beer drinkers who have a specific genetic variant in the cluster of three genes that metabolize alcohol are at significantly higher risk of developing non-cardia gastric cancer, according to research presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Scientists from Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine are working on a series of genetic analyses that suggest the underlying differences among racial groups are present not just in tumors, but in normal tissue as well. Lisa Baumbach, Ph.D., associate research professor, and colleagues will present the full study results at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Researchers directed by Dr. Laurent Mottron at the University of Montreal’s Centre for Excellence in Pervasive Development Disorders (CETEDUM) have determined that people with autism concentrate more brain resources in the areas associated with visual detection and identification, and conversely, have less activity in the areas used to plan and control thoughts and actions.
Cancer is at its most treatable when caught early, so scientists are increasing their focus on innovative diagnostic methods that, hopefully, will lead to higher cure rates.
A panel of biomarkers appears to be able to identify the presence of lung cancer in the blood samples of people who have never smoked, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Researchers investigating a novel biomarker test believe it is the most accurate yet in detecting proteins secreted from tumors caused by exposure to asbestos. Study results of this aptamer proteomic technology were presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Breast cancer risk can be assessed by examining the epithelial cells found in breast milk, according to preliminary study results presented at the AACR 102nd Annual Meeting 2011, held April 2-6.
Researchers at NYU Langone Medical Center have investigated a novel protein test to detect early-stage, asbestos-related pulmonary cancer. The test can accurately identify proteins secreted from cancerous tumors caused by asbestos exposure. The study was presented at the American Association for Cancer Research 102nd Annual Meeting 2011 on April 4th.
Nicotine at doses similar to those found in most nicotine replacements therapies did not increase lung cancer tumor incidence, frequency or size, according to results of a mouse study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
The use of aspirin at least once per month is associated with a significant decrease in pancreatic cancer risk, according to results of a large case-control study presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
Researchers with the International Agency for Research on Cancer (IARC) have found that people with lung cancer were significantly more likely to have several high-risk forms of human papillomavirus (HPV) antibodies compared to those who did not have lung cancer. These results, which were presented at the AACR 102nd Annual Meeting 2011, held April 2-6, indicate that HPV antibodies are substantially increased in people with lung cancer.
Medicare coverage and nationwide utilization of computed tomographic colonography (CTC), commonly referred to as virtual colonoscopy, has tripled in recent years, according to a study in the April issue of the Journal of the American College of Radiology (www.jacr.org). CTC employs virtual reality technology to produce a three-dimensional visualization that permits a thorough and minimally invasive evaluation of the entire colon and rectum. CT colonography is an alternative to conventional optical colonoscopy for colorectal cancer screening and diagnosis.
Results of the NIH-AARP Diet and Health Study revealed that diabetes is associated with lower risk of prostate cancer in men but with higher risk of other cancers in both men and women. The data, to be presented at the AACR 102nd Annual Meeting 2011, held here April 2-6, also showed an association between diabetes and higher cancer mortality rates.
Smoking increases the risk of breast cancer, but the risk differs by obesity status in postmenopausal women, according to data from an analysis of the Women’s Health Initiative observational study.
Scientists have confirmed that metabolic syndrome, a constellation of conditions that increases the risk of heart disease and diabetes, may also increase the risk of the two most common types of liver cancer, according to data presented at the AACR 102nd Annual Meeting 2011, held here April 2-6.
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