Focus: Hidden - Virginia

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The University of Virginia Darden School of Business welcomed eight new professors to its top-ranked faculty ahead of the 2018–19 academic year. The new professors will bolster ranks in the academic areas of Quantitative Analysis, Accounting, Global Economies and Markets, and Leadership and Organizational Behavior.

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As sea levels rise due to climate change, so do the global hazards and potential devastating damages from tsunamis, according to a new study by a partnership that included Virginia Tech.

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The American Thyroid Association has awarded a 2018 Research Grant to Ann-Kathrin Eisfeld, MD, Clinical Fellow in Internal Medicine at Ohio State University. The topic of Dr. Eisfeld’s project is “Novel NRAS isoform mediates BRAF-inhibitor resistance in papillary thyroid cancer—thinking outside the box to overcome ‘inevitable’ treatment failure.” Papillary thyroid cancer (PTC) is one of the 10 most common malignancies in the United States, with almost 60,000 new people diagnosed each year. While almost all patients initially respond well to the current standard treatment with radioactive iodine, almost half of them will eventually develop resistance. Therapies that can provide additional treatment options for those patients are greatly needed.

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The American Thyroid Association has awarded a 2018 Research Grant to Cintia Eliana Citterio, PhD, Assistant Professor of Genetics and Molecular Biology at the Instituto de Inmunología, Genética y Metabolismo (INIGEM), Universidad de Buenos Aires (UBA) - Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET). Dr. Citterio’s project is called “De novo triiodothyronine (T3) formation in T3 toxicosis of Graves’ Disease.” The project focuses on identifying T3-forming sites in thyroglobulin (TG, the protein from which thyroid hormone is made) that are responsible for excess T3 production in patients with autoimmune hyperthyroidism or Graves’ Disease (GD).

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The American Thyroid Association has awarded a 2018 Research Grant to Nicholas J. Tardi, PhD, Instructor in Internal Medicine at Rush University Medical Center in Chicago. Dr. Tardi’s project is titled “Deiodinase 3: A Thyroid Hormone-Associated Renoprotective Protein.” The long-term goal of this project is to identify the source and mechanism of kidney and thyroid comorbidity. Thyroid hormone (TH) is a circulating, lipid-soluble molecule that plays an important physiological and developmental role in nearly all cells. Accordingly, precise control of TH activity is crucial to maintain metabolic homeostasis in several tissues.

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The American Thyroid Association has awarded a 2018 Research Grant to Wayne Miles, PhD, Assistant Professor of Molecular Genetics at the Ohio State University. Dr. Miles’s research project is entitled “Proteomic-led discovery of essential genes in Medullary Thyroid Cancer.” Medullary thyroid cancer (MTC) is caused by the malignant growth of C-cells. Although MTC represents only a small fraction (2¬4%) of all thyroid cancer cases and overall survival rates from MTC are good, patients diagnosed with advanced disease have poor five-year survival rates (28%). The genetic aberrations of the cancer result in C-cells receiving a continuous signal to grow and proliferate. To sustain their elevated growth rates, MTC cells adapt their genome (DNA), transcriptome (RNA), and proteome (the entire set of proteins expressed by a cell, tissue, or organism).

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The American Thyroid Association has awarded a 2018 Research Grant to Miles Miller, PhD, principal investigator at the Massachusetts General Hospital Center for Systems Biology and Assistant Professor of Radiology at Harvard Medical School. Dr. Miller’s research project is titled “Co-opting tumor-associated macrophages in anaplastic thyroid cancer to enhance immune-checkpoint blockade response.” Treatment of advanced metastatic cancer has seen a revolution over the last several years, as new therapeutic strategies have become successful at harnessing the power of the immune system to durably attack malignant and mutated cancer cells. Immune-checkpoint blockade therapies targeting programmed-death 1 (PD1) signaling on T-cells have been successful in the treatment of solid cancers, including heavily mutated melanomas and lung cancers. Unfortunately, these treatments only work in a fraction of patients, and resistance is often associated with the presence of a type of tumor-promoting imm

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The American Thyroid Association has awarded a 2018 Research Grant to Stephanie Behringer-Massera, MD, Clinical Fellow at the Icahn School of Medicine at Mount Sinai. Dr. Behringer-Massera’s project is titled “T regulatory cells in thyroid-antibody-positive pregnant women.” A fetus, which shares half its genetic material with the father, is considered a foreign body in the mother’s womb. The only way that it can implant in the uterus without being rejected is if the mother’s immune system is suppressed, which happens through T-regulatory-cell action. The more T regulatory cells (Tregs) are released, the more the immune system is suppressed and the more likely the pregnancy can successfully be brought to term. In women with autoimmune thyroid disease, this process is disrupted. These women are found to have an abnormal Treg response to pregnancy and have Treg levels as low as women who are not pregnant. They are more likely to have miscarriages in the first trimester.

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A new study carried out at the Department of Energy's Thomas Jefferson National Accelerator Facility has confirmed that increasing the number of neutrons as compared to protons in the atom’s nucleus also increases the average momentum of its protons. The nuclear physics result, which has implications for the dynamics of neutron stars, has been published in the journal Nature.

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The Academy of Management (AOM) awarded University of Virginia Darden School of Business Professor Ed Freeman the 2018 Award for Distinguished Scholarly Contributions to Management at its annual meeting in Chicago on 12 August.

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The American Thyroid Association has awarded a 2018 Research Grant to Brendan Frett, PhD, Assistant Professor in the College of Pharmacy at the University of Arkansas for Medical Sciences. The title of Dr. Frett’s project is “Dual Inhibition of RET and Aurora B to Study the Simultaneous Regulation of Multiple Oncogene Pathways in Medullary Thyroid Cancer.” Since its inception in 1971, the War on Cancer has resulted in significant treatment breakthroughs. One of the most important was the discovery of cancer-promoting oncogenes (genes with the potential to cause cancer). Researchers theorized that oncogenes could be strategically targeted while sparing normal cells, which sparked the era of precision medicine for oncology. Early medicine discoveries were quickly followed by the realization that secondary mutations in cancers often resulted in resistance to the drugs and relapse of the disease. This was solved by generating inhibitors that achieved activity on multiple forms of the onc

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Joseph W. Polli, Ph.D., FAAPS, GlaxoSmithKline has been elected to serve as president-elect of the American Association of Pharmaceutical Scientists (AAPS), a professional member-based organization of approximately 9,000 located in Arlington, VA.

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The Darden School of Business’ Institute for Business in Society partners with Concordia and the U.S. Department of State Secretary’s Office of Global Partnerships to present the annual P3 Impact Award, which recognizes leading public-private partnerships that improve communities around the world.

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The American College of Radiology Liver Imaging Reporting and Data System (LI-RADS®) steering committee developed and approved a new version of CT/MRI LI-RADS (v2018), thus reaching a critical milestone of integration into the American Association for the Study of Liver Diseases (AASLD) 2018 hepatocellular carcinoma (HCC) clinical practice guidance.

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Employer expectations of work email monitoring during nonwork hours are detrimental to the health and well-being of not only employees but their family members as well.

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The American Thyroid Association (ATA®) is pleased to announce that Dr. Angela M. Leung has been selected as the new Editor-in-Chief of the ATA monthly journal Clinical Thyroidology®, as of 2019. Clinical Thyroidology is one of the ATA official journals distributed electronically. This highly valued abstract and commentary publication provides a broad-ranging look at the clinical thyroid literature. Experts in the field summarize the most cutting-edge, relevant articles of which clinicians should be aware and provide insight into the relevance and impact of each article on patient care.

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Taylor Sheppard remains on active duty even as a second-year student at the Darden School of Business, where the two-year curriculum fit nicely with her two-year “shore tour” assignment. Between classes, she frequently checks in with UVA’s Navy ROTC unit — her current assigned unit — and she will return to submarine tours after school.

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Tsampa Tsnacks — the “t” is silent — might look similar to other “energy ball” snacks, but they are different in their main ingredient and the intention of their creators. Chenam Barshee and Sogyel Lhungay (MBA ’18) call their product “Tibetan fuel for the mind and body.”

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The Myositis Association is pleased to announce the appointment of Mary McGowan as Executive Director.

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Papers on nephrotoxicity, nanomaterial genotoxicity, machine learning; arsenic and telomere length in children; iPSC-derived cardiomyoctes for drug safety studies; and asthma, air pollution, and immunity featured in latest issue of Toxicological Sciences

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The study, which has yielded a provisional patent, establishes a method for wicking chemically compatible vegetable oils into the surfaces of common extruded plastics.

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The American Chiropractic Association (ACA) and its members will encourage the public to move more – to “Move 4 Life” – during National Chiropractic Health Month 2018 (NCHM) this October.

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In May, the Darden School of Business announced plans for the Initiative for Transformational Leadership and Learning, a multidisciplinary effort to develop a learning laboratory devoted to novel, scientifically verified leadership development.

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A University of Virginia Health System program that provides follow-up care for heart failure patients after they leave the hospital significantly improves survival and other outcomes while saving money, a new study finds.

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Astronomers have made the first definitive detection of a radioactive molecule in interstellar space: a form, or isotopologue of aluminum monofluoride (26AlF). The new data – made with ALMA and the NOEMA radio telescopes – reveal that this radioactive isotopologue was ejected into space by the collision of two stars, a tremendously rare cosmic event that was witnessed on Earth as a “new star,” or nova, in the year 1670.

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Warshall, who graduated from the University of Virginia Darden School of Business in 2014; Paul Dierkes, the softball teammate; and Joel Artz started Snowing in Space, a Charlottesville-based coffee business known for its nitro cold brew coffee, in 2016.

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Akanksha Prasad (Class of 2019) came to Darden after selling the successful falafel restaurant business she founded in India

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The Electron-Ion Collider Center at the Department of Energy’s Thomas Jefferson National Accelerator Facility (EIC Center at Jefferson Lab) has announced the winners of four fellowships to pursue research related to a proposed electron-ion collider over the next year.

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Astronomers using ALMA studied a cataclysmic stellar explosion known as a gamma-ray burst, or GRB, and found its enduring “afterglow.” The rebound, or reverse shock, triggered by the GRB’s powerful jets slamming into surrounding debris, lasted thousands of times longer than expected. These observations provide fresh insights into the physics of GRBs, one of the universe’s most energetic explosions.

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The members of the American Society for Radiation Oncology (ASTRO) have elected four new officers to ASTRO’s Board of Directors and four members to serve on the medical society’s Nominating Committee. The newly elected President-elect, Council Vice-chairs and Nominating Committee members will begin their terms during ASTRO’s 60th Annual Meeting in San Antonio this October.

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The results of the first ever clinical trial of focused ultrasound to open the blood-brain barrier (BBB) in patients with Alzheimer’s disease were published today in Nature Communications and also presented at the Alzheimer’s Association International Conference (AAIC) in Chicago, Illinois. The pilot trial demonstrated the feasibility and preliminary safety of focally, reversibly and repetitively opening the BBB.

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The American Society for Radiation Oncology (ASTRO) has selected 35 distinguished members to receive the ASTRO Fellow (FASTRO) designation. The 2018 class of Fellows will be recognized during ASTRO’s 60th Annual Meeting, to be held October 21-24 in San Antonio.

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Finalists for the 2018 P3 Impact Award were announced by the Office of Global Partnerships at the U.S. Department of State, the University of Virginia Darden School of Business Institute for Business in Society and Concordia. The award recognizes exemplary public-private partnerships (P3s) that provide solutions to pressing issues in areas such as: economic development, housing, health and sanitation, and workforce.

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Darden alumna Meg Greenhalgh creates Brandefy, an app that helps consumers decide between generic and name-brand products through ingredient comparisons and user reviews, and closed an initial funding round.

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University of Virginia Darden School of Business Professors Ed Freeman and Bobby Parmar presented their talk, The New Story Business, to a standing room-only crowd in San Francisco on 17 July.

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The American College of Radiology (ACR) has released four new and 23 revised documents in the 2018 Practice Parameters and Technical Standards.

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The following statement is being issued by the U.S. Department of Energy’s Thomas Jefferson National Accelerator Facility and Brookhaven National Laboratory—along with the Electron-Ion Collider User Group—in response to a report issued today by the National Academies of Sciences, Engineering, and Medicine on the scientific case for a U.S.-based Electron-Ion Collider (EIC). Jefferson Lab and Brookhaven scientists are part of the vibrant community that has come together to tackle the scientific and technological challenges of designing and building a U.S.-based EIC, drawing on the expertise and existing infrastructure at the two labs.

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According to the newly released 2018 Journal Citation Report (JCR), the Journal of the American College of Radiology (JACR) has achieved a 2017 Impact Factor of 3.383, a 16 percent increase over last year’s impact factor of 2.929. JACR is now ranked third among general radiology journals and 28th among all 128 journals JCR categorizes as Radiology, Nuclear Medicine and Medical Imaging, up two spots from our 30th ranking last year.

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The Food and Drug Administration (FDA) approved the American College of Radiology’s (ACR’s) amendment to the 2016 Alternative Standard #24 to the “Quality control tests--other modalities” requirement. This FDA review and approval of the ACR Digital Breast Tomosynthesis (DBT) quality control (QC) test procedures enables the College to incorporate DBT into the 2016 ACR Digital Mammography Quality Control Manual.

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The American Chiropractic Association (ACA), supported by chiropractic organizations across the country, strongly opposes a new policy by UnitedHealthcare (UHC) that denies headache sufferers the option to treat their pain without drugs using spinal manipulative therapy (SMT).

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The latest research on the environment in the Environmental Science News Source

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The latest research and feature news on vision in the Vision News Source

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Go here for the latest political experts, features and research in U.S. Politics

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In July, Darden School of Business alumnus Eric Bernath (MBA ’08) crossed what was to be his final border of a 100,000-mile trip around the world, riding his motorcycle into his home state of Michigan after an epic 65 country, 50-state road trip conducted on his Suzuki V-Strom 650 motorcycle.

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A mother’s microbiome, the collection of microscopic organisms that live inside us, determines the risk of autism and other neurodevelopmental disorders in her offspring, new research from the UVA School of Medicine shows. The research suggests that we may be able to prevent autism just by altering an expectant mother's diet or by giving her custom probiotics.

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Another global financial crisis will come eventually, although when and why the next great downturn will begin remains an unknown. So far, regulatory efforts have not eliminated the sources of financial instability. UVA Darden professor Bob Bruner offers precipitating factors.

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UVA Darden Professor Saras Sarasvathy is on a mission to revolutionize entrepreneurship education.Through her work, she has identified a distinct logic that underlies entrepreneurial behavior. She dubbed it “effectuation.”