Feature Channels: Pharmaceuticals

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Newswise: Anti-inflammatory drug celecoxib could reduce risk of colon cancer recurrence for a subset of patients
18-Jun-2024 10:05 AM EDT
Anti-inflammatory drug celecoxib could reduce risk of colon cancer recurrence for a subset of patients
Dana-Farber Cancer Institute

An analysis of data from a randomized clinical trial for patients with stage 3 colon cancer found that those with PIK3CA mutations who took celecoxib, an anti-inflammatory drug, after surgery lived significantly longer and had longer disease-free survival compared to those without the mutation.

Newswise: Confronting the Backlash Against QALYs: 
Key Insights From Leading Health Economists
Released: 18-Jun-2024 4:05 AM EDT
Confronting the Backlash Against QALYs: Key Insights From Leading Health Economists
ISPOR—The Professional Society for Health Economics and Outcomes Research

ISPOR announced the publication of a collection of papers that examine the long-standing debate surrounding the use of quality-adjusted life years (QALYs) and alternative measures in healthcare decision making.

Newswise: New tool could facilitate discovery of new mechanically responsive materials
Released: 17-Jun-2024 9:05 AM EDT
New tool could facilitate discovery of new mechanically responsive materials
College of Liberal Arts and Sciences, University of Illinois Urbana-Champaign

Newly published research details the development of an easy-to-use intuitive tool that can predict without lengthy experimentation and calculation the reactivity of C-C bonds when designing mechanophores, which could lead to the discovery of new mechanically responsive materials.

Released: 14-Jun-2024 3:05 PM EDT
Novel Gene-Editing Therapy Continues to Show Positive Results in Sickle Cell Patients
Cleveland Clinic

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

Released: 14-Jun-2024 8:05 AM EDT
High out-of-pocket costs may be barrier to filling naloxone prescriptions, study shows
Michigan Medicine - University of Michigan

A study finds naloxone prescriptions, given to prevent opioid overdoses, are less likely to be filled when cost-sharing is higher, including at the start of a new health insurance year.

Newswise: Cole_Parmer__Logo.jpg
Released: 13-Jun-2024 1:05 PM EDT
Cole-Parmer Is Back in Peristaltic Pumps
Cole-Parmer

Cole-Parmer, an Antylia Scientific company, is pleased to reintroduce peristaltic pumps to enhance its industry-leading line of fluid handling solutions.

Newswise: Research could lead to treatments for obesity, extreme weight loss
Released: 13-Jun-2024 12:05 PM EDT
Research could lead to treatments for obesity, extreme weight loss
UT Southwestern Medical Center

Mysterious cells that secrete hormones in the large intestine play a key role in regulating body weight through their relationship with intestinal bacteria, a study led by UT Southwestern Medical Center researchers suggests. Their findings, published in Nature Metabolism, could lead to new treatments for obesity and extreme weight loss.

Newswise: NSF CAREER grant to investigate design of fluorescent protein sensors with computer simulations that may aid human health and disease
Released: 12-Jun-2024 4:05 PM EDT
NSF CAREER grant to investigate design of fluorescent protein sensors with computer simulations that may aid human health and disease
Wayne State University Division of Research

Alice Walker, Ph.D., assistant professor of chemistry in the College of Liberal Arts and Sciences at Wayne State University, received a Faculty Early Career Development (CAREER) award from the National Science Foundation to fund her research on applying computational chemistry to the understanding and rational design of new fluorescent protein (FP) sensors.

   
Newswise: ‘Synthetic’ Cell Shown to Follow Chemical Directions and Change Shape, A Vital Biological Function
10-Jun-2024 10:00 AM EDT
‘Synthetic’ Cell Shown to Follow Chemical Directions and Change Shape, A Vital Biological Function
Johns Hopkins Medicine

In a feat aimed at understanding how cells move and creating new ways to shuttle drugs through the body, scientists at Johns Hopkins Medicine say they have built a minimal synthetic cell that follows an external chemical cue and demonstrates a governing principle of biology called “symmetry breaking.”

Newswise: Unregulated Sales of a Toxic and Hallucinogenic Mushroom Endanger Public Health
Released: 10-Jun-2024 12:05 PM EDT
Unregulated Sales of a Toxic and Hallucinogenic Mushroom Endanger Public Health
University of California San Diego

Americans' interest in a potentially harmful "magic mushroom" is soaring, according to a new study by researchers at the University of California San Diego Herbert Wertheim School of Public Health and Human Longevity Science.

Newswise: Super-Chilled Brain Cell Molecules Reveal How Epilepsy Drug Works
Released: 10-Jun-2024 11:00 AM EDT
Super-Chilled Brain Cell Molecules Reveal How Epilepsy Drug Works
Johns Hopkins Medicine

By super cooling a molecule on the surface of brain cells down to about minus 180 degrees Celsius — nearly twice as cold as the coldest places in Antarctica — scientists at Johns Hopkins Medicine say they have determined how a widely-used epilepsy drug works to dampen the excitability of brain cells and help to control, although not cure, seizures.

Newswise: Decoding salvia miltiorrhiza: a molecular approach to boosting bioactive compounds
Released: 7-Jun-2024 6:05 AM EDT
Decoding salvia miltiorrhiza: a molecular approach to boosting bioactive compounds
Chinese Academy of Sciences

Salvia miltiorrhiza, known as Danshen, is widely used in traditional Chinese medicine for treating cardiovascular diseases, cancer, and Alzheimer's disease. The medicinal properties of Danshen are primarily attributed to its two major bioactive compounds: tanshinones and phenolic acids.

Newswise: Advances in Omics Research of Rosaceae
Released: 7-Jun-2024 2:05 AM EDT
Advances in Omics Research of Rosaceae
Chinese Academy of Sciences

A research team has provided a comprehensive overview of the applications of omics technologies in Rosaceae plants.

Released: 6-Jun-2024 8:05 AM EDT
UL Solutions and ScienceMedia Partner to Revolutionize Training and e-Learning Solutions for Life Sciences
ScienceMedia

ScienceMedia announced today that it has formed a partnership with UL Solutions that offers ComplianceWire®, the industry leading learning management system (LMS) tailored toward compliance and qualification management within life sciences organizations.

Newswise: Monell Researchers Identify Universal Bitter Blocker that Could Help Patients Take Their Life-Saving Medicines as Prescribed
Released: 5-Jun-2024 12:05 PM EDT
Monell Researchers Identify Universal Bitter Blocker that Could Help Patients Take Their Life-Saving Medicines as Prescribed
Monell Chemical Senses Center

Strong bitterness is the main reason why people all over the world, especially children, avoid taking their medicines, putting their health, and sometimes, their lives at risk. Now, a group of scientists at the Monell Chemical Senses Center identified the first temporary, universal taste blocker that works in people.

Newswise: Researchers detect traces of heart meds in fish from West Virginia rivers
Released: 5-Jun-2024 11:00 AM EDT
Researchers detect traces of heart meds in fish from West Virginia rivers
West Virginia University

Statins and beta blockers are working their way into the aquatic ecosystem, according to West Virginia University researchers who have discovered evidence of the cardiovascular drugs in fish collected from two West Virginia rivers.

   
30-May-2024 9:05 AM EDT
Largest-ever antibiotic discovery effort uses AI to uncover potential cures in microbial dark matter
Perelman School of Medicine at the University of Pennsylvania

Almost a century ago, the discovery of antibiotics like penicillin revolutionized medicine by harnessing the natural bacteria-killing abilities of microbes. Today, a new study co-led by researchers at the Perelman School of Medicine at the University of Pennsylvania suggests that natural-product antibiotic discovery is about to accelerate into a new era, powered by artificial intelligence (AI).

   
Newswise: Molecular switch linked to lineage plasticity, therapy resistance
Released: 4-Jun-2024 12:05 PM EDT
Molecular switch linked to lineage plasticity, therapy resistance
UT Southwestern Medical Center

Two genes working in tandem play a critical role in shaping the identity and behavior of prostate cancer cells and their response to treatment, UT Southwestern Medical Center researchers report.



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