Feature Channels: Autoimmune Diseases

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Rutgers and Duke University professors explore how to improve care and reduce the use of antipsychotic medications in nursing homes

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In a study looking at brain scans of people with mild loss of thought and memory ability, Johns Hopkins researchers report evidence of lower levels of the serotonin transporter — a natural brain chemical that regulates mood, sleep and appetite.

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An international team of scientists, led by University of California San Diego School of Medicine researchers, has created a human stem cell-based model of a rare, but devastating, inherited neurological autoimmune condition called Aicardi-Goutieres Syndrome (AGS). In doing so, the team was able to identify unusual and surprising underlying genetic mechanisms that drive AGS and test strategies to inhibit the condition using existing drugs.

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Mayo Clinic researchers, along with colleagues at the University of Iowa, report that a human gut microbe discovered at Mayo Clinic may help treat autoimmune diseases, such as multiple sclerosis. The findings appear in Cell Reports.

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As Alzheimer’s disease and other forms of dementia continue to become more prevalent, it may not be long before there is a push for legalizing physician-assisted death (PAD) in dementia cases in the United States.American officials must thoroughly consider the moral and social consequences of such an action, says an expert on medical ethics at Washington University in St.

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The brains of aged chimpanzees, our closest living relatives, show pathology similar to the human Alzheimer’s disease (AD) brain, according to a new, multi-institution research study.

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Researchers at Penn Medicine have discovered that a patient’s awareness of a diagnosis of cognitive impairment may diminish their self-assessment of quality of life.

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Rita Cowell, Ph.D., has joined the Southern Research as Chair of the Neuroscience Department as it expands research and drug discovery efforts focusing on diseases such as Parkinson’s and Alzheimer’s.

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Press can register here to livestream this special session through Newswise Live on Monday, July 31 at 7:30 PM EDT

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The push to develop treatments for Alzheimer’s disease has yielded a greater understanding of the disease, but has failed to generate successful new drugs. To blame are the many undefined subtypes of mild cognitive impairment, a precursor to Alzheimer’s disease. But if scientists grouped people with similar types of cognitive impairment, they could more precisely test the impact of investigational drugs, according to findings in a July 28 article in the journal Scientific Reports, a publication of Nature Research.

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A new method may help determine whether a person has Alzheimer’s disease or frontotemporal dementia, two different types of dementia that often have similar symptoms, according to a preliminary study published in the July 26, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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In a new study published today, Arizona State University-Banner Health neuroscientist Salvatore Oddo and his colleagues from Phoenix’s Translational Genomics Research Institute (TGen) — as well as the University of California, Irvine, and Mount Sinai in New York — have identified a new way for brain cells to become fated to die during Alzheimer’s diseases.

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People who carry a genetic susceptibility to Alzheimer’s disease appear to be at greater risk of diminished cognition from sleep-disordered breathing than those without the susceptibility, according to new research published online, ahead of print in the Annals of the American Thoracic Society.

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A report by the first Lancet Commission on Dementia Prevention and Care identifies powerful tools to prevent dementia and touts the benefits of nonmedical interventions for people with dementia.

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A new study led by researchers at Washington University School of Medicine in St. Louis suggests that measures of amyloid beta in the blood have the potential to help identify people with altered levels of amyloid in their brains or cerebrospinal fluid. Currently, the only way to detect amyloid beta in the brain is via PET scanning or a spinal tap.

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Emergency and urgent hospitalizations are associated with an increased rate of cognitive decline in older adults, report researchers at Rush University Medical Center. The results of their study suggest that hospitalization may be a more of a major risk factor for long-term cognitive decline in older adults than previously recognized.

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Three new gene variants, found in a genome wide association study of Alzheimer’s disease (AD), point to the brain’s immune cells in the onset of the disorder. These genes encode three proteins that are found in microglia, cells that are part of the brain’s injury response system.

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Researchers from the University of Colorado School of Medicine have discovered that a process that protects the body from autoimmune disease also prevents the immune system from generating antibodies that can neutralize the HIV-1 virus. The findings, which will be published July 11 in The Journal of Experimental Medicine, might be considered by scientists trying to develop a vaccine that can stimulate the production of these neutralizing antibodies.