It is a commonly held that information on Wikipedia should not be trusted, since it is written and edited by non-experts without professional oversight. But researchers from the Kimmel Cancer Center at Jefferson have found differently, according to a study published online Sept. 1 in the Journal of Oncology Practice.
Clinicians can monitor kidney function with a simple equation.
1) Merkel cell polyomavirus induces cell transformation in unexpected ways. 2)Discoveries help narrow possible treatments. 3) Virus functions differently than other cancer-related viruses.
1) Despite KRAS, lack of EGFR blocks pancreatic cancer development. 2) EGFR plays an “unappreciated” central role early in the carcinogenic process.
1) Virus construct may work to kill pancreatic cancer cells. 2) Therapeutic response to virus treatment can be noninvasively monitored. 3) Virus construct could facilitate targeted radiotherapy.
1) Researchers work to identify key pathways for cancer progression. 2) Approach may help identify new targeted therapies. 3) Global picture demonstrates how genes interact to affect cancer progression.
1) These lethal brain cancers depend on cholesterol for growth. 2) Laboratory findings identified a tumor survival pathway. 3) Glioblastoma is one of the most untreatable cancers.
Blocking the uptake of large amounts of cholesterol into brain cancer cells could provide a new strategy to battle glioblastoma, one of the most deadly malignancies, researchers at UCLA’s Jonsson Comprehensive Cancer Center have found.
A new study of interracial marriages in the United States since the 1980s suggests that the racial boundary between blacks and whites continues to break down – but is not yet close to disappearing.
A new study, conducted in part at the University of North Carolina at Chapel Hill, finds that a 24-week triple medication treatment course for hepatitis C is just as effective as a 48-week regimen.
Study reveals link between early number sense and elementary math scores.
In a first of its kind study, researchers have found that using two way audio-video telemedicine to deliver stroke care, also known as telestroke, appears to be cost-effective for rural hospitals that don’t have an around-the-clock neurologist, or stroke expert, on staff. The research is published in the September 14, 2011, online issue of Neurology®, the medical journal of the American Academy of Neurology.
Medical imaging experts at Johns Hopkins have reviewed the patient records of 302 men and women who had a much-needed X-ray of the blood vessels near the spinal cord and found that the procedure, often feared for possible complications of stroke and kidney damage, is safe and effective.
Heart specialists at Johns Hopkins have figured out how a widely used pacemaker for heart failure, which makes both sides of the heart beat together to pump effectively, works at the biological level. Their findings, published in the September 14 issue of Science Translational Medicine, may open the door to drugs or genetic therapies that mimic the effect of the pacemaker and to new ways to use pacemakers for a wider range of heart failure patients.
Why are African Americans more likely than Caucasians to be not only diagnosed with head and neck cancer, but also die from the disease? While the answer isn’t a simple one, differences in lifestyle, access to care and tumor genetics may, in part, be to blame, according to a new study from Henry Ford Hospital.
In the quest to understand genomes—how they’re built, how they’re organized and what makes them work—a team of Johns Hopkins researchers has engineered from scratch a computer-designed yeast chromosome and incorporated into their creation a new system that lets scientists intentionally rearrange the yeast’s genetic material. A report of their work appears September 14 as an Advance Online Publication in the journal Nature.
Researchers at Henry Ford Hospital in Detroit say HPV is much more likely to be found in tumors of laryngeal (voice box) cancer patients who are male and those with private health insurance, a finding that could impact head and neck cancer screening and treatment.
Making use of a new “super resolution” microscope that provides sharp images at extremely small scales, scientists have achieved unprecedented views of the immune system in action.
During the past two decades there has been a significant increase in the percentage of patients who have a high number of lymph nodes evaluated during colon cancer operations, but this improvement is not associated with an increase in the overall proportion of colon cancers that are node positive, according to a study in the September 14 issue of JAMA.
While the incidence of the life-threatening condition of aortic dissection is significantly higher than in the general population, it remains low among patients with the congenital heart defect, bicuspid aortic valve; however, the incidence of aortic aneurysms is significantly high, according to a study in the September 14 issue of JAMA.
The use of stronger graduated driver licensing programs for 16- to 19-year old drivers in the U.S. that included restrictions on nighttime driving and allowed passengers were associated with a lower incidence of fatal crashes among 16-year old drivers, but a higher incidence among 18-year olds, according to a study in the September 14 issue of JAMA.
A Henry Ford Hospital study has identified 23 microRNAs for laryngeal cancer, 15 of which had yet to be reported in head and neck cancer. The researchers say the discovery could yield new insight into what causes certain cells to grow and become cancerous tumors in the voice box.
Researchers from Mount Sinai School of Medicine have for the first time used several imaging techniques to prove the efficacy of a promising new treatment for atherosclerosis—the build-up of plaque in artery walls that can lead to a heart attack.
People with high cholesterol may have a higher risk of developing Alzheimer’s disease, according to a study published in the September 13, 2011, issue of Neurology®, the medical journal of the American Academy of Neurology.
An enzyme that appears to play a role in controlling the brain's response to nicotine and alcohol in mice might be a promising target for a drug that simultaneously would treat nicotine addiction and alcohol abuse in people, according to a study by researchers at the Ernest Gallo Clinic and Research Center, affiliated with the University of California, San Francisco.
The Mayo Clinic Center for Innovation (CFI) announced today that Best Buy® is the founding consortium member of a new “living lab” in the Charter House, a continuing care retirement community in Rochester. John Noseworthy, M.D., President and CEO of Mayo Clinic, made the announcement at the Transform 2011 symposium today.
A research team led by Fred Hutchinson Cancer Research Center has discovered proteins in the blood that are associated with early lung cancer development in mice and humans. The advance brings the reality of a blood test for the early detection and diagnosis of lung cancer a step closer.
The latest evidence for NVC-422’s power against biofilms comes from a just-published study by researchers at the University of Adelaide in Australia. The study focused on sinusitis, an ailment marked by an inflammation of the paranasal sinuses, often as a consequence of a bacterial infection.
Young children who watch fast-paced, fantastical television shows may become handicapped in their readiness for learning, according to a new University of Virginia study published in the October issue of the journal Pediatrics.
Findings could potentially impact counseling, screening of women with BRCA mutation.
New research from the University of Alabama at Birmingham pinpoints the relationship between primary brain tumors and the onset of epileptic seizures and reveals that a drug used to treat Crohn’s disease inhibits those seizures and may be able to slow a tumor’s growth. The onset of seizures is a common symptom in gliomas and often is the first sign of a brain tumor. Sen. Ted Kennedy had a seizure in May 2008, and three days later doctors confirmed that he had a malignant glioma. Kennedy died the following year.
New technique gives cats protection genes.
In a study published today (Sunday, Sept. 11), researchers at the University of Wisconsin-Madison report the first full measurement of the proteins made by both types of stem cells. In a study that looked at four embryonic stem cells and four IPS cells, the proteins turned out to be 99 percent similar, says Joshua Coon, an associate professor of chemistry and biomolecular chemistry who directed the project.
1) High blood levels of the hormone FGF-23 warn of heart problems, need for dialysis, and early death among chronic kidney disease patients. 2) Tests for FGF-23 could identified those at risk. 3) 60 million people globally have chronic kidney disease, and most die from heart-related problems.
Study indicates infants at risk for autism could benefit from motor training.
Nearly 50,000 Americans are diagnosed each year with stage III or locally advanced NSCLC, for which surgery is usually not a viable treatment option. Optimizing nonsurgical treatment strategies for these patients is an ongoing research endeavor. In the August xx, 2011 issue of the Journal of the National Cancer Institute, RTOG researchers report that treating patients with concurrent chemotherapy and radiation therapy significantly increased five-year survival rates compared with treating patients with radiation therapy upon completion of chemotherapy treatment.
Scientists have suggested that some ancient sharks bred in the shallows of freshwater lakes, forming nurseries for their hatchlings. Reporting in the most recent issue of the Journal of Vertebrate Paleontology, a team of German paleontologists support this claim with spectacular 230 million-year-old fossil egg capsules and tiny teeth from Kyrgyzstan.
By looking to Mother Nature for solutions, researchers have identified a promising new binder material for lithium-ion battery electrodes that could not only boost energy storage, but also eliminate the use of toxic compounds now used in manufacturing the components.
University of Maryland researchers patented and licensed a “Bio-glue” that allows simulation of mechanical and chemical heartbeats from a single cell.
--Physician referral to Weight Watchers® is more than twice as effective as standard care--
Patients with narrowed arteries in the brain who received intensive medical treatment had fewer strokes and deaths than patients who received a brain stent in addition to medical treatment, according to the initial results from the first, nationwide stroke prevention trial to compare the two treatment options. The results of the National Institutes of Health (NIH) study called Stenting versus Aggressive Medical Management for Preventing Recurrent Stroke in Intracranial Stenosis (SAMMPRIS) are published in the online first edition of the New England Journal of Medicine.
An article appearing in the Sept. 7 New England Journal of Medicine, reporting on NIH research on brain stents, says aggressive medical treatment without stenting is better for high-risk stroke patients. But experts at Cedars-Sinai Medical Center who were involved in the study believe this procedure is appropriate for some patients. They say this study is a helpful start but not likely to be the final word on understanding when stenting may be appropriate, and raise concerns about several study limitations and exclusions.
People who received intensive medical treatment following a first stroke had fewer second episodes and were less likely to die than people who received brain stents in addition to medical treatment, according to a new report in the New England Journal of Medicine, to be published online Sept. 7. All patients in the study had experienced one stroke and were considered at high risk for a second one.
Dana-Farber Cancer Institute researchers have discovered a pair of backup circuits in cancer cells that enable the cells to dodge the effect of cetuximab. Until now, scientists haven't known why cancers that initially respond to cetuximab become resistant to it, or how to overcome such resistance.
Researchers at Mount Sinai School of Medicine have identified a new drug target that may treat and/or prevent heart failure, published in this week's Nature.
A somewhat mysterious soft tissue found in the fetus during early development in the womb plays a pivotal role in the formation of mature beta cells the sole source of the body’s insulin. This discovery, made by scientists at University of California, San Francisco (UCSF) and Texas A&M University, may lead to new ways of addressing Type 1 and Type 2 diabetes.
New Johns Hopkins research shows that medical students — just like the general American population — may have unconscious if not overt preferences for white people, but this innate bias does not appear to translate into different or lesser health care of other races.
Inherited BRCA1 gene mutation associated with better response to neoadjuvant chemotherapy in breast cancer patients.
An analysis led by Mayo Clinic (http://www.mayoclinic.org/) researchers found that simulation-based training is an effective way to teach physicians, nurses, dentists, emergency medical technicians and other health professionals.
The risk of miscarriage is 2.4 times greater for women who took any type and dosage of nonaspirin nonsteroidal anti-inflammatory drugs (NSAIDs) in early pregnancy, according to a University of Montreal study in CMAJ.
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