Feature Channels: Immunology

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Released: 18-Aug-2020 11:05 AM EDT
Biomedical scientists piece together how medication paralyzes parasitic worms
Iowa State University

A new study upends the widely held belief that a medication used to treat lymphatic filariasis doesn’t directly target the parasites that cause the disease. The research shows the medication, diethylcarbamazine, temporarily paralyzes the parasites.

   
14-Aug-2020 5:45 PM EDT
LJI team gets first-ever look at a rare but vital stem cell in humans
La Jolla Institute for Immunology

Scientists at La Jolla Institute for Immunology (LJI) have tracked down the rare stem cells that generate neutrophils in human bone marrow. This research, published August 18, 2020, in Immunity, gives researchers a potential path for intervening in diseases where neutrophil development goes awry.

Released: 18-Aug-2020 9:10 AM EDT
Acidic Niche Keeps Lymphatic System in Check during Immune Response, Moffitt Researchers Say
Moffitt Cancer Center

In a new article published in Nature Communications, Moffitt Cancer Center researchers describe a novel acidic niche within lymph nodes that plays an integral role in regulating T cell activation.

Released: 17-Aug-2020 3:35 PM EDT
Mild COVID-19 cases can produce strong T cell response
Cell Press

Mild cases of coronavirus disease 2019 (COVID-19) can trigger robust memory T cell responses, even in the absence of detectable virus-specific antibody responses, researchers report August 14 in the journal Cell.

Released: 17-Aug-2020 1:40 PM EDT
Protein Produced by the Nervous System May Help Treatments for Inflammatory Diseases
Rutgers University-New Brunswick

A Rutgers-led team may have found the key to treating inflammatory diseases like asthma, allergies, chronic fibrosis and chronic obstructive pulmonary disease (COPD).

Released: 17-Aug-2020 6:00 AM EDT
Live Press Conference: Immunotherapy extends survival in mouse model of hard-to-treat breast cancer (video)
American Chemical Society (ACS)

A press conference on this topic will be held Tuesday, Aug. 17, at 10 a.m. Eastern time online at www.acs.org/fall2020pressconferences.

11-Aug-2020 8:00 AM EDT
Immunotherapy extends survival in mouse model of hard-to-treat breast cancer (video)
American Chemical Society (ACS)

Today, scientists report a new immunotherapy that extends the survival of mice that have triple negative breast tumors, a difficult-to-treat form of cancer. The researchers will present their results at the American Chemical Society Fall 2020 Virtual Meeting & Expo.

17-Aug-2020 2:05 AM EDT
Keck Medicine of USC enrolling volunteers for phase 3 clinical trial for COVID-19 vaccine
Keck Medicine of USC

Keck Medicine of USC launches phase 3 trial for COVID-19 vaccine. To ensure access for underrepresented and vulnerable populations, researchers are setting up a satellite location in the meat-packing community of Vernon, CA.

Released: 11-Aug-2020 6:50 PM EDT
Protein uses two antiviral strategies to ward off infections
eLife

To protect humans against infection, a protein called MARCH8 tags the vesicular stomatitis virus (VSV) for destruction while it merely holds HIV hostage, a new study in eLife shows.

10-Aug-2020 1:00 PM EDT
Immunotherapy-Resistant Cancers Eliminated in Mouse Study
Washington University in St. Louis

In a mouse study, researchers at Washington University School of Medicine in St. Louis have found that an antibody that targets the protein TREM2 empowers tumor-destroying immune cells and improves the effectiveness of cancer immunotherapy.

Released: 7-Aug-2020 3:25 PM EDT
Scientists Discover Curious Clues in the War Between CF Bacteria
University of North Carolina School of Medicine

This research shows that both Pseudomonas and Burkholderia use toxic weaponry, called Type VI Secretion Systems (T6SS), to compete with and establish dominance over each other. It could be possible to target or mimic this weaponry to defeat the bacteria before they cause irreparable lung damage.

Released: 7-Aug-2020 9:45 AM EDT
Potentially predictive humoral immune response markers in COVID-19 patients
Massachusetts General Hospital

Galit Alter, PhD, Group Leader at the Ragon Institute of MGH, MIT and Harvard and Professor of Medicine at Harvard Medical School, and Helen Chu, MD, Associate Professor of Medicine, Division of Allergy and Infectious Diseases, University of Washington School of Medicine, and UW Medicine physician, have recently published a paper which identifies five immune response markers which, collectively, were able to correctly classify both convalescent COVID-19 patients and those who did not survive the disease

Released: 5-Aug-2020 2:50 PM EDT
New findings on enzymes with important role in SARS-CoV-2 infection
Uppsala University

Researchers at Uppsala University have described the presence, throughout the human body, of the enzyme ACE2.

Released: 5-Aug-2020 2:00 PM EDT
Cancer Research Institute Awards $30.2 Million in Grants and Fellowships to Support Basic and Clinical Research in Immunology and Cancer Immunotherapy
Cancer Research Institute

The Cancer Research Institute (CRI), a U.S. nonprofit organization dedicated to the discovery and development of powerful immunotherapies for all cancers, awarded more than $30.2 million in research grants and fellowships in the 2020 fiscal year ending June 30, 2020.

Released: 4-Aug-2020 10:00 AM EDT
Exposure to common cold coronaviruses can teach the immune system to recognize SARS-CoV-2
La Jolla Institute for Immunology

A new study led by scientists at La Jolla Institute for Immunology (LJI) shows that memory helper T cells that recognize common cold coronaviruses also recognize matching sites on SARS-CoV-2, the virus that causes COVID-19.

Released: 4-Aug-2020 10:00 AM EDT
Researchers develop new mouse model for SARS-CoV-2
The Rockefeller University Press

Researchers at Yale University School of Medicine have developed a new mouse model to study SARS-CoV-2 infection and disease and to accelerate testing of novel treatments and vaccines against the novel coronavirus. The study, published today in the Journal of Experimental Medicine (JEM), also suggests that, rather than protecting the lungs, key antiviral signaling proteins may actually cause much of the tissue damage associated with COVID-19.

Released: 3-Aug-2020 9:00 AM EDT
Neutrolis Announces Development Of First-In-Class Treatment Targeting Neutrophil Extracellular Traps (NETs) For Patients With Severe COVID-19
Neutrolis

Novel Chromatinase™ platform could rapidly and systemically removes NETs associated with exacerbation of COVID-19

   
Released: 30-Jul-2020 4:10 PM EDT
Could prior exposure to common cold viruses affect the severity of SARS-CoV-2 symptoms?
Charité - Universitätsmedizin Berlin

A study led by Charité - Universitätsmedizin Berlin and the Max Planck Institute for Molecular Genetics (MPIMG) shows that some healthy individuals possess immune cells capable of recognizing the novel coronavirus, SARS-CoV-2.

23-Jul-2020 10:55 AM EDT
The big gulp: Inside-out protection of parasitic worms against host defenses
Morgridge Institute for Research

A team of developmental biologists at the Morgridge Institute for Research has discovered a means by which schistosomes, parasitic worms that infect more than 200 million people in tropical climates, are able to outfox the host’s immune system.



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