Immune cells use two different routes to produce acetyl-CoA, an essential metabolite required to fight infection and cancer, reports a study led by Van Andel Institute scientists.
Scientists at Sanford Burnham Prebys and the La Jolla Institute for Immunology have revealed a new secret regarding senescence, a cellular state similar to sleep that is more likely to affect aged cells.
Today the U.S. Department of Energy (DOE) announced $19.5 million in funding over three years for 14 projects on low-dose radiation – studying the cellular and molecular responses to doses of radiation that are at or near lower exposure limits.
The University of Texas MD Anderson Cancer Center’s Research Highlights showcases the latest breakthroughs in cancer care, research and prevention. These advances are made possible through seamless collaboration between MD Anderson’s world-leading clinicians and scientists, bringing discoveries from the lab to the clinic and back.
Irvine, Calif., Aug. 20, 2024 — A team of researchers led by the University of California, Irvine has discovered that an antioxidant found in rosemary extract can reduce volitional intakes of cocaine by moderating the brain’s reward response, offering a new therapeutic target for treating addiction. The study, recently published online in the journal Neuron, describes team members’ focus on a region of the brain called the globus pallidus externus, which acts as a gatekeeper that regulates how we react to cocaine.
An extensive family of proteins that gives human skin mechanical strength also appears to organize molecular signals that control skin cell activity, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Developmental Cell, could lead to new ways to fight a host of skin diseases, including ulcers and skin cancer.
Researchers from UC San Diego are working on a new treatment for Alzheimer's that targets tau - a type of protein in the brain that helps cells retain their stability and structure.
Eight-member team from UChicago and Northwestern will launch the Cellular Adaptation Lab to study how fundamental cellular behaviors are linked to disease and responses to climate change.
The AAI Council is pleased to announce the appointment of Bonnie N. Dittel, Ph.D. (AAI ’00), as the incoming editor-in-chief of ImmunoHorizons (IH).
Rutgers Cancer Institute, the state’s only National Cancer Institute-designated Comprehensive Cancer Center together with RWJBarnabas Health, has treated its 200th patient with CAR T-cell therapy, a type of immunotherapy that uses a patient’s own immune cells to fight cancer.
In a marked advance over current AI models, the new approach captures how proteins act not in isolation but in their cellular and tissue environments.
The sea anemone Nematostella vectensis is potentially immortal. Using molecular genetic methods, developmental biologists led by Ulrich Technau from the University of Vienna have now identified possible candidates for multipotent stem cells in the sea anemone for the first time. These stem cells are regulated by evolutionary highly conserved genes, which in humans are usually only active in the formation of egg and sperm cells, but give ancient animal phyla such as cnidarians a high degree of regenerative capacity to even escape ageing. The results are currently being published in Science Advances and could also provide insights into the human ageing process in the future.
Moffitt Cancer Center researchers have developed a novel reagent that enhances the precision of drug synthesis. This innovative method, published in Nature Communications, introduces a new sulfur fluoride exchange (SuFEx) reagent that allows for highly controlled production of crucial sulfur-based molecules, including sulfinamides, sulfonimidamides and sulfoximines.
Taghreed Mohammed Al-Turki, PhD, a postdoctoral researcher in the UNC Lineberger lab of Jack Griffith, PhD, describes her long, difficult, and rewarding journey of becoming a telomere scientist as a first-time mother at the University of North Carolina School of Medicine.
In what they labeled a “surprising” finding, Johns Hopkins Medicine researchers studying bacteria from freshwater lakes and soil say they have determined a protein’s essential role in maintaining the germ’s shape.
The coordinated activity of brain cells, like birds flying in formation, helps us behave intelligently in new situations, according to a study led by Cedars-Sinai investigators.
A pivotal study uncovers the molecular signatures of mammographic calcifications in hormone receptor-positive, HER2-negative breast cancer.
Neutrophils are an important type of white blood cell that help your immune system fight infections. One of the many ways neutrophils help is by capturing germs in sticky, spider web-like structures called neutrophil extracellular traps, or NETs.However, excessive formation of NETs is seen in many autoimmune diseases as a sign of exuberant inflammation.
Microscopy engineers at Washington University in St. Louis model how molecules move to enhance understanding of nanoscale biological systems.
Natural killer (NK) cells engineered to express interleukin-21 (IL-21) demonstrated sustained antitumor activity against glioblastoma stem cell-like cells (GSCs) both in vitro and in vivo, according to new research from The University of Texas MD Anderson Cancer Center.
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