A new USDA-supported project based at Iowa State University will create an encyclopedia of livestock species' genetic regulatory regions, a DNA netherworld that could be useful in breeding for improved animal efficiency and health.
Mayo Clinic researchers mined the molecular foundations of cancer and uncovered a new reason chimeric antigen receptor (CAR-T cell therapy) fails in some patients. This discovery has fueled new strategies that incorporate antibodies and gene editing to improve the outcome of this breakthrough treatment for patients.
In a study of 12 participants, researchers at Beth Israel Deaconess Medical Center (BIDMC) have demonstrated that a cocktail of three broadly neutralizing antibodies (bNAb) successfully suppressed virus in people living with HIV. A subset of participants also demonstrated long-term control of the virus months after antibody levels declined to low or undetectable.
A protein called torsinA plays a key role in the early development of neurons, determining where nuclear pores are placed in the membrane that encloses the nucleus of nerve cells, a study led by UT Southwestern Medical Center researchers shows.
NYU Tandon School of Engineering is spearheading a novel initiative aimed at expanding access to semiconductor design education, supporting key objectives of the bipartisan CHIPS and Science Act and bolstering NYU's growing prominence in chip design.
A real-time adaptive optics system was developed, characterised and applied to measure the 3D flow field through an oscillating surface of a water drop on an opaque Gas Diffusion Layer. A case study shows that the system corrects successfully measurement errors of the flow field that are caused by the refraction of light at the time-varying water-air interface.
An international team led by Professor Gong Xiao from the National University of Singapore has developed a groundbreaking non-volatile photonic-electronic memory chip, published in Light: Science & Applications.
New research from the University of Washington found lockdowns during the COVID-19 pandemic resulted in unusually accelerated brain maturation in adolescents. This maturation was more pronounced in girls. When measured in terms of the number of years of accelerated brain development, the mean acceleration was 4.2 years in females and 1.4 years in males.
A four-year, $1.2 million grant from the National Cancer Institute of the National Institutes of Health to Wayne State University may help researchers find new clues to the interplay between Down syndrome and myeloid leukemia.
University of California, Irvine scholars, scientists and physicians continue to blaze new paths to help improve the world. In fiscal 2023-24, which ended June 30, UC Irvine received the most research funding in campus history: $668 million in grants and contracts.
Cancer cells appear to hijack a genetic pathway involved in DNA repair to drive malignancy and overcome treatment, a study led by UT Southwestern Medical Center researchers shows. Their findings, published in Cell, explain how chromosomes in some tumors undergo massive rearrangements and could lead to new strategies to avoid cancer drug resistance.
Ten structures of URAT1 obtained by scientists at St. Jude Children’s Research Hospital provide a deep understanding of the mechanism of urate transport to guide gout therapeutic design.
Researchers at the University of Michigan Health Rogel Cancer Center have uncovered a key reason why a typically normal protein goes awry and fuels cancer. They found the protein NSD2 alters the function of the androgen receptor, an important regulator of normal prostate development.
2024 JSA Postdoctoral Prize Winner Debaditya Biswas will combine different particle identification methods with machine learning to detect muons hidden in a sea of pions.
Until recently, it was believed that human urine is sterile, but advanced culturing techniques and DNA sequencing have revealed that bacteria and other microbes – such as viruses and fungi – inhabit the human bladder and urinary tract, known collectively as the “urobiome.” Now in study that is one of the first of its kind, Dr.
A study led by researchers at Beth Israel Deaconess Medical Center (BIDMC) found the risk of developing Parkinson’s disease was 76 percent higher among those with a history of damage to the lining of their upper gastrointestinal (GI) tract than among those without.
Age-related changes in the fibroblasts, cells that create the skin’s structure, contribute to the development of aggressive, treatment-resistant melanoma in males, according to research in mice by the Johns Hopkins Kimmel Cancer Center.
Scleroderma is a chronic autoimmune disease of women.Over time, people living with scleroderma develop progressive and irreversible scarring.Scarring, called fibrosis, effects the lungs, heart and kidneys, leading to poor quality of life, disability and a reduced life expectancy.
Large-scale testing of self-managed auricular point acupressure for non-pharmaceutical pain management in rural communities is the focus of a new federal grant awarded to researchers with Cizik School of Nursing at UTHealth Houston.
Physical human feats require a high level of coordination between the sensory functions of our skin and motor functions of our muscles. What kind of achievements could robots perform with the same cohesion between sensing and action? In the medical space, researchers have begun to explore the possibilities.
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