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15-Feb-2019 1:00 PM EST
Mapping Brain Circuits in Newborns May Aid Early Detection of Autism
Children's Hospital of Philadelphia

A new map of newborn babies’ brains offers details of structure that will provide a new reference for researchers studying both typical brain development and neurological disorders. Using noninvasive, 20-minute MRI scans, researchers have revealed some of the complex and precisely organized brain architecture that emerges as the brain reshapes itself during the third trimester of pregnancy.

15-Feb-2019 4:05 PM EST
Penn Medicine and CHOP Study Finds that Fetal Signaling Pathways May Offer Future Targets for Treating Lung Injury
Perelman School of Medicine at the University of Pennsylvania

A new animal study describes how cells that become alveoli, the tiny compartments in which gas exchange occurs in the lung, begin their specialized roles very early in prenatal life. Investigating the fetal signaling pathways active in this biological event may offer future opportunities to treat lung damage caused by prematurity and other lung injuries.

18-Feb-2019 11:00 AM EST
New Insight Into the Balance Between the Tumor-suppressive and Tumor-promoting Effects of Cellular Senescence
Wistar Institute

Researchers at The Wistar Institute have described a novel role of nicotinamide adenine dinucleotide (NAD+) metabolism in the ability of senescent cells to release tumor-promoting molecules.

   
Released: 14-Feb-2019 3:05 PM EST
Immune Profiling: A New Opportunity for Drug Development
Perelman School of Medicine at the University of Pennsylvania

Collectively, assessing a snapshot of a person’s unique state of immune health is called immune profiling, which can entail identifying immune-cell-associated genes and proteins, as well as the cell types themselves.

Released: 14-Feb-2019 2:05 PM EST
Single Word Most Associated with Negative Hospital Reviews on Yelp is 'Told'
Perelman School of Medicine at the University of Pennsylvania

A Penn Medicine research team found that the word “told” was tied to almost 20 percent of poor reviews

Released: 14-Feb-2019 2:05 PM EST
When Research Participation Pays, Some People Lie, Penn Study Suggests
Perelman School of Medicine at the University of Pennsylvania

Offering compensation can be an important tactic to attract potential participants for enrollment in research studies, but it might come at a cost. A new study conducted by researchers in the Perelman School of Medicine at the University of Pennsylvania found that up to 23 percent of respondents lied about their eligibility to participate in a survey when offered payment, even small amounts.

Released: 14-Feb-2019 1:05 PM EST
Neural processing with trauma and adversity interact to increase core symptom of PTSD
Elsevier

Lifetime adversity and increased neural processing during a traumatic event combine to increase the frequency of intrusive traumatic memories and the distress they cause, according to a new study in Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.

Released: 14-Feb-2019 10:15 AM EST
The Medical Minute: Helping caregivers address mental health concerns
Penn State Health

Caregiver jobs often come loaded with pressures. In fact, caregivers face a higher risk of developing a mental health disorder because of the stress that can accompany taking care of others.

Released: 14-Feb-2019 10:00 AM EST
Combination of T Cell Therapy and Targeted Therapy as a Novel Strategy for Therapy-resistant Melanoma with Mutations in the BRAF Gene
Wistar Institute

Collaborative research by The Wistar Institute and Moffitt Cancer Center has demonstrated that BRAF targeted therapies render resistant melanoma more sensitive to the attack of killer T cells.

   
Released: 13-Feb-2019 12:05 PM EST
In Defense of Millennials, the Global Generation
Perelman School of Medicine at the University of Pennsylvania

The word “millennial” isn’t exactly a compliment these days. The problem is, all the criticisms out there – “they’re too picky!” or “they’re entitled!” or “they spend all their money on lattes and avocado toast!” – have left it mostly with a negative connotation and rarely a positive one. Any praise for those born between 1981 and 1996 seems to be quickly drowned out by the headlines, memes, and social media posts reinforcing the same old stereotypes of an entire generation. But, in all fairness, millennials are also known to be altruistic, ambitious, and passionate about social injustices, more so than previous generations, many have argued. A USA Today article even described them as the most civic-minded generation in over half a century.

Released: 13-Feb-2019 10:30 AM EST
Drug-Resistant TB Cured with New Approaches in Conflict-Affected Region
Health Sciences at the University of Pittsburgh

A high proportion of multidrug-resistant tuberculosis (TB) cases can be cured in conflict-affected communities with molecular diagnostics, shorter treatment periods and socioeconomic incentives, according to the results of a large, long-term study in the Democratic Republic of Congo.

Released: 13-Feb-2019 10:20 AM EST
New Book from Sociologist Daniel Laurison Explores the ‘Class Ceiling’
Swarthmore College

In his new book, The Class Ceiling: Why it Pays to Be Privileged, Assistant Professor of Sociology Daniel Laurison '99 investigates the ambiguities of meritocracy in white-collar workers’ salaries in the United Kingdom.

Released: 12-Feb-2019 11:30 AM EST
Annual 2019 Diversity and Inclusion Conference, sponsored by Temple University, returns to Philadelphia
Temple University

The 2019 Diversity & Inclusion Conference, held March 25-26 in Philadelphia, is an open forum to explore and exchange insights about diversity and inclusion (D&I) best practices for CEOs, diversity officers, educators, corporate leaders and government officials.

Released: 11-Feb-2019 3:00 PM EST
Researchers Identify Brain Protein Crucial to Recovery from Stroke
Health Sciences at the University of Pittsburgh

Researchers at the University of Pittsburgh School of Medicine have identified a brain protein at the root of how the brain recovers from stroke. The finding offers a promising avenue for developing therapies that could work even when given beyond the first few hours after a stroke.

8-Feb-2019 4:05 PM EST
For the First Time, Scientists ‘See’ Dual-Layered Scaffolding of Cellular Nuclei
Health Sciences at the University of Pittsburgh

Using super-sensitive microscopic imaging, a team of scientists made a fundamental biological discovery that explains the structure of the nuclear envelope and gives tantalizing clues as to how cells squish through narrow openings without springing a leak.

Released: 11-Feb-2019 12:05 PM EST
Potent marijuana edibles can pose a major unrecognized risk to patients with cardiovascular disease
Elsevier

Philadelphia, February 11, 2019 - As marijuana legalization sweeps North America, use of the substance has been on the rise, and the public's attitude is shifting. An increasing number of people believe that "weed" is the safest recreational drug, one that carries health benefits that outweigh its risks.

Released: 11-Feb-2019 11:00 AM EST
Federal Funding Fueled Growth of Wistar Science in 2018
Wistar Institute

The Wistar Institute announces that it was awarded more than $16M in federal research funds in support of its groundbreaking research in cancer, immunology and infectious diseases.

   
4-Feb-2019 8:00 AM EST
Prior Dengue Infection Protects Against Zika
Health Sciences at the University of Pittsburgh

The higher a person’s immunity to dengue virus, the lower their risk of Zika infection, an international team of scientists led by the University of Pittsburgh Graduate School of Public Health, Yale School of Public Health and University of Florida report today in the journal Science.

   
5-Feb-2019 4:10 PM EST
Engineered DNA Vaccine Protects Against Emerging Mayaro Virus Infection
Wistar Institute

A novel, synthetic DNA vaccine developed at The Wistar Institute induces protective immunity against Mayaro virus (MAYV), a mosquito-borne infection endemic to South America, that has the potential to become a global emerging viral threat.

   
Released: 6-Feb-2019 2:05 PM EST
In Their DNA: Rotator Cuff Stem Cells More Likely to Develop into Fat Cells
Wolters Kluwer Health: Lippincott

Why are fat deposits more likely to occur after tears of the shoulder’s rotator cuff, compared to other types of muscle injuries? An increased propensity of stem cells within with rotator cuff muscles to develop into fat cells may explain the difference, reports a study in the February 6, 2019 issue of The Journal of Bone & Joint Surgery. The journal is published in the Lippincott portfolio in partnership with Wolters Kluwer.



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