Feature Channels: Clinical Trials

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Newswise: From ‘trial and error’ to targeted precision: $17.9M grant accelerates mental health research
Released: 9-Jul-2024 5:05 AM EDT
From ‘trial and error’ to targeted precision: $17.9M grant accelerates mental health research
Michigan Medicine - University of Michigan

A major new grant will fund a study enrolling thousands of people from the time they schedule a mental health appointment, and gather data that could form the basis for precisely targeted treatment in future.

Newswise: First Patient Receives ACES™ Automatic Continuous Effusion Shunt System at UNC School of Medicine for Pleural Effusion
Released: 2-Jul-2024 2:05 PM EDT
First Patient Receives ACES™ Automatic Continuous Effusion Shunt System at UNC School of Medicine for Pleural Effusion
University of North Carolina School of Medicine

In collaboration with the company Pleural Dynamics, researchers at the UNC School of Medicine are the first to use a fully implantable automatic effusion shunt with no external catheters or expensive drainage canisters to provide an innovative new option for patients who struggle with chronic fluid collection.

Released: 2-Jul-2024 10:05 AM EDT
New MSU study finds systematic biases at play in clinical trials
Michigan State University

MSU has a satellite uplink/LTN TV studio and Comrex line for radio interviews upon request.

30-Jun-2024 4:00 PM EDT
Cancer Center Clinical Research Capacity and Benchmarking in the Post-Pandemic Era
Association of American Cancer Institutes (AACI)

"North American Cancer Center Clinical Research Capacity and Benchmarking in the Post-Pandemic Era" was published July 1 in JCO Oncology Practice, an American Society of Clinical Oncology (ASCO) Journal.

Newswise: Respiratory Societies Help Bring the World Together for Bronchiectasis
Released: 1-Jul-2024 9:05 AM EDT
Respiratory Societies Help Bring the World Together for Bronchiectasis
American Thoracic Society (ATS)

In support of the third annual World Bronchiectasis Day, July 1, the Forum of International Respiratory Societies (FIRS), of which the American Thoracic Society is a founding member, is joining the COPD Foundation and several global organizations to raise awareness, share knowledge, and discuss ways to reduce the burden of bronchiectasis for patients and their families worldwide.

25-Jun-2024 12:05 PM EDT
Antibody-Drug Conjugate Highly Effective in Preventing Recurrence in Patients with Early Stage HER2+ Breast Cancer, Trial Finds
Dana-Farber Cancer Institute

• 97% of HER2+, early-stage patients treated with trastuzumab emtansine (T-DM1) were free of cancer recurrence five years after treatment • Prognostic test (HER2DX) shown helpful in identifying patients at greatest risk for recurrence

Released: 26-Jun-2024 12:05 PM EDT
Advancing regenerative medicine therapies
University of California, Irvine

University and community guests recently gathered to celebrate the 7,700 square-foot Good Manufacturing Practice facility’s grand opening in Hewitt Hall’s basement on the UC Irvine campus. Although the highly sterile environment remains off-limits for tours, the gala highlighted its importance to the campus, the UC system and the local community.

20-Jun-2024 12:45 PM EDT
New Survey from NCCN Finds Cancer Drug Shortage Management Remains a Moving Target, Impacting Clinical Trials
National Comprehensive Cancer Network® (NCCN®)

NCCN shares new data on continued high prevalence for cancer drug shortages in the United States. In the latest survey, carboplatin and cisplatin shortages fell to 11% and 7% respectively, but 89% of centers surveyed continue to report shortages for at least one type of systemic therapy; 75% are experiencing two or more drug shortages.

Newswise: Researchers report first effective use of immunotherapy for most common subtype of colorectal cancer
Released: 25-Jun-2024 1:05 PM EDT
Researchers report first effective use of immunotherapy for most common subtype of colorectal cancer
Dana-Farber Cancer Institute

These clinical trial results point to the first safe and effective use of immunotherapy for patients with microsatellite stable colorectal cancer, the most common subtype of the disease. The encouraging results of this phase I trial have prompted Dana-Farber investigators to move forward with a phase III trial of this immunotherapy combination.

Newswise: Electroconvulsive therapy or ketamine? Clinical factors affect outcomes
Released: 25-Jun-2024 11:05 AM EDT
Electroconvulsive therapy or ketamine? Clinical factors affect outcomes
UT Southwestern Medical Center

Patients with moderate to severe treatment-resistant depression (TRD) might have better symptom relief from ketamine infusions than from electroconvulsive therapy (ECT), but those with severe TRD could benefit more from ECT early in treatment, an analysis led by a UT Southwestern Medical Center researcher shows. The findings, published in JAMA Network Open, are the first to identify characteristics that distinguish which treatments might benefit TRD patients more.

Newswise: Study Identifies First Drug Therapy for Sleep Apnea
18-Jun-2024 1:05 PM EDT
Study Identifies First Drug Therapy for Sleep Apnea
UC San Diego Health

UC San Diego School of Medicine international study shows new drug improves sleep, health in patients diagnosed with obesity and sleep apnea.

Released: 20-Jun-2024 10:30 AM EDT
Kids from disadvantaged communities may die sooner from cancerous brain tumors
Michigan Medicine - University of Michigan

Children with inoperable brain tumors may die sooner if they live in areas with lower average income and education levels, a Michigan Medicine-led study finds. Income and educational attainment, the researchers suggest, may affect the landscape of diagnosis and treatment of brain tumors. 

Released: 19-Jun-2024 12:05 PM EDT
Modifying homes for stroke survivors saves lives, extends independence
Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have found that safety interventions – such as walkers, grab bars, ramps and other home modifications – allow many stroke survivors to keep living independently in their homes and may reduce their risk of death.

Newswise: Breakthrough UC San Diego Brain Recording Device Receives FDA Approval for a Clinical Trial
Released: 19-Jun-2024 7:00 AM EDT
Breakthrough UC San Diego Brain Recording Device Receives FDA Approval for a Clinical Trial
University of California San Diego

The Federal Drug Administration approved a clinical trial to test the effectiveness of an electronic grid that records brain activity during surgery, developed by engineers at the University of California San Diego.

Newswise: Anti-inflammatory drug celecoxib could reduce risk of colon cancer recurrence for a subset of patients
18-Jun-2024 10:05 AM EDT
Anti-inflammatory drug celecoxib could reduce risk of colon cancer recurrence for a subset of patients
Dana-Farber Cancer Institute

An analysis of data from a randomized clinical trial for patients with stage 3 colon cancer found that those with PIK3CA mutations who took celecoxib, an anti-inflammatory drug, after surgery lived significantly longer and had longer disease-free survival compared to those without the mutation.

Released: 14-Jun-2024 3:05 PM EDT
Novel Gene-Editing Therapy Continues to Show Positive Results in Sickle Cell Patients
Cleveland Clinic

Researchers have presented the latest findings from a clinical trial aimed at discovering a cure for sickle cell disease, a painful genetic blood disorder with limited treatment options.

Released: 13-Jun-2024 11:15 AM EDT
Wren Laboratories Unveils Dynamic Executive Leadership Team and 2024 Commercial Strategy Overhaul
Wren Laboratories

Wren Laboratories announced executive leadership for commercial operations and market expansion. Dr. Abdel Halim is appointed CEO and CSO. Troy Tremaine Appointed to CCO, Dr. Eva Szarek Head of Marketing, and Melissa Ferone director of quality. Expansion includes AI-driven mRNA liquid biopsy genomic assays for biopharma and diagnostics.

Newswise: 1920_nieminen1.jpeg?10000
Released: 11-Jun-2024 12:05 PM EDT
New Atrial Fibrillation Treatment Gets Dad His Beat Back
Cedars-Sinai

Everyone knows exhaustion is a rite of passage for new parents, which is why Henric Nieminen ignored the symptoms at first.

Newswise: Discovery in hibernating animals could extend the shelf life of cells and tissues for transplantation  
Released: 11-Jun-2024 12:05 PM EDT
Discovery in hibernating animals could extend the shelf life of cells and tissues for transplantation  
NIH, National Eye Institute (NEI)

Research led by scientists at the National Eye Institute and Sun Yat-sen University, Guangzhou, China points to a potential strategy for extending the cold storage shelf life of donor cells and tissues, such as those of the pancreas, an organ crucial for making insulin.

Newswise: Team tests strategies to care for patients with multiple diseases
Released: 11-Jun-2024 10:05 AM EDT
Team tests strategies to care for patients with multiple diseases
UT Southwestern Medical Center

In a large clinical trial, UT Southwestern Medical Center researchers developed a robust model for testing strategies to prevent health problems in patients with multiple chronic conditions.



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