Feature Channels: AIDS and HIV

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Researchers at the UNC School of Medicine’s International Center for the Advancement of Translational Science and the Institute for Global Health and Infectious Diseases have developed a new approach for the detailed evaluation of HIV infection throughout the entire male genital tract, HIV acquisition via the penis and the efficient prevention of penile HIV infection. The study was published in mBio by the American Society of Microbiology.

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Below are summaries of recent Fred Hutchinson Cancer Center research findings and other news. If you’re covering the American Society for Clinical Oncology’s annual meeting, June 2-6 in Chicago, Illinois, see our list of Fred Hutch research highlights at ASCO and contact [email protected] to set up interviews with experts.

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Read about new melanoma treatment practices, how models provide information about a rare adrenal cancer, a potential oral medication for brain cancer, and clinical trials for cancer patients with HIV.

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Scientists have spent years trying to develop an effective HIV vaccine, but none have proven successful. Based on findings from a recently published study, a Johns Hopkins Medicine-led research team may have put science one step closer to that goal.

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Skin cancer is the most prevalent form of cancer in the United States, with over 5 million cases diagnosed annually. The Centers for Disease Control and Prevention reports that melanoma alone accounts for more than 8,000 deaths each year. Thankfully, skin cancer is highly preventable, making it crucial to prioritize protection. Below are some of the latest headlines in the Dermatology channel.

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An international study led by MELIS-UPF researchers from the Infection Biology and Molecular Virology laboratories has identified and characterized Schlafen 12 (SLFN 12) as a novel HIV restriction factor.

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Rutgers Institute for Health researcher, Dr. Ashley Grosso, receives grant from NIH to conduct study on barriers to HIV research in Africa.

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Patients with mpox who were treated with the antiviral drug tecovirimat had similar outcomes regardless of HIV status, find researchers at Columbia University and Weill Cornell Medicine.

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Gene-editing therapy aimed at two targets – HIV-1, the virus that causes AIDS, and CCR5, the co-receptor that helps the virus get into cells – can effectively eliminate HIV infection. The study is the first to combine a dual gene-editing strategy with antiretroviral drugs to cure animals of HIV-1.

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Researcher will discuss the study which involved a sleeping aid known as suvorexant that is already approved by the Food and Drug Administration (FDA) for insomnia, hints at the potential of sleep medications to slow or stop the progression of Alzheimer’s disease.

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UC Davis Health researchers have dosed the second participant in their clinical trial looking to identify a potential cure for HIV utilizing CART-cell therapy.

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Below are some of the latest headlines in the new Avian Flu channel on Newswise.