This week, a 40-year-old patient was treated at UNC’s Clinical and Translational Research Center (CTRC) with SB-913, an investigational genome editing therapy for individuals with mucopolysaccharidosis type II (MPS II), a rare lysosomal storage disorder also known as Hunter syndrome.
A new report finds that extremely obese people who have a band surgically strapped around their stomachs to restrict food intake not only lose weight but also suffer less from arthritic knee pain.
Tissue-engineering technique based on a novel cylindrical scaffolding design seeded with collagen-secreting cells yields grafts for articular cartilage repair with superior mechanical strength and durability.
Scientists are bringing precision medicine to rheumatoid arthritis for the first time by using genetic profiling of joint tissue to see which drugs will work for which patients, reports a new Northwestern Medicine multi-site study.In the near future, patients won’t have to waste time and be disappointed with months of ineffective therapy, scientists said.
An Ohio integrated health system and a national social enterprise have announced a new alliance to mobilize tens of millions of dollars for underinvested communities—starting with a $45 million effort to scale up economic opportunity and improve health outcomes in Toledo and the surrounding region over the next decade.
The heart-healthy Mediterranean diet also appears to be good for an older woman’s bones and muscles, a new study of postmenopausal women in Brazil finds. The study results will be presented Monday at ENDO 2018, the Endocrine Society’s 100th annual meeting in Chicago, Ill.
New research presented at ENDO 2018 links semen count to other health problems
Cells made by fusing a normal human muscle cell with a muscle cell from a person with Duchenne muscular dystrophy —a rare but fatal form of muscular dystrophy — were able to significantly improve muscle function when implanted into the muscles of a mouse model of the disease. The findings are reported by researchers from the University of Illinois at Chicago in the Stem Cell Reviews and Reports.
Spin caloritronics explores how heat currents transport electron spin, and researchers are particularly interested in how waste heat could be used to power next-generation spintronic devices. The thermally driven transport application of spin caloritronics is based on the Seebeck effect; researchers in China have theoretically exposed the fundamental aspects of this thermal transport along double-stranded DNA molecules. They reported their findings in the Journal of Applied Physics.
For the first time, scientists at Wake Forest Baptist Medical Center have been able to measure a specific molecule indicative of osteoarthritis and a number of other inflammatory diseases using a newly developed technology.
Recent statistics from the U.S. Centers for Disease Control and Prevention show that almost one-third of all childhood injuries are sports-related, and that more than half of those are preventable.
The absence of TTP, a protein critical to the control of inflammation, may lead to rapid and severe bone loss, according to a new study led by the University at Buffalo.
Mercy Medical Center orthopedic surgeon Dr. Rebecca Cerrato is one of the first surgeons in the United States to offer minimally invasive bunion surgery, an alternative to traditional surgery that can reduce post-surgical scarring, swelling and pain
Many hip disorders are the result of chronic undiagnosed conditions caused when active women push themselves beyond their limits.
The American College of Rheumatology has published a new white paper, “The Science Behind Biosimilars — Entering a New Era of Biologic Therapy,” which shares the organization’s stance that it is reasonable for physicians to begin integrating the prescription of biosimilars as another option of medication in patient treatment, where appropriate. S. Louis Bridges Jr., M.D., Ph.D., director of the University of Alabama at Birmingham’s Division of Clinical Immunology and Rheumatology, served as the lead author on the paper.
Medicare’s experimental mandatory bundled payment model for knee and hip replacements is more likely to yield cost savings when the surgeries are performed in larger hospitals that do more of these procedures, according to a study from the Perelman School of Medicine at the University of Pennsylvania. Non-profit and major teaching hospital status also appear to be associated with cost savings, the Penn Medicine analysis found.
Dislocation is one of the most common complications after hip replacement and the number one reason for revision surgery. Researchers at Hospital for Special Surgery found that study patients who received a newer implant known as a “dual mobility” hip replacement had zero dislocations.
Christopher Rowles, 59, was sidelined after losing half of his leg to amputation in 2011. Thanks to a new technique called osseointegration, he's back to pursuing his favorite hobby -- river fishing. Rowles is one of the first people in the country to undergo the novel procedure, which permanently anchors a titanium implant into the leg bone.
By studying mice in late adolescence, Johns Hopkins University researchers have discovered that the rapid bone growth associated with puberty is slowed not only by fewer cartilage cell divisions but also by the “aging” of bone cell precursor cells. After investigating the signaling molecules that promote this transition, the scientists conclude that some weak and brittle bone conditions in both children and adults may be due to the cells’ premature “retirement” caused by glucocorticoid treatments given during puberty to treat chronic inflammation resulting from rheumatoid disorders and other diseases.
Research led by orthopedic surgeon James D. Slover, MD of NYU Langone Health, reveals that people with undiagnosed neurocognitive deficits are undergoing hip and knee replacements at high rates and are more likely to have poorer short-term outcomes after surgery.
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