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Newswise: New AI Tool Finds Rare Variants Linked to Heart Disease in 17 Genes
10-Jun-2024 5:00 AM EDT
New AI Tool Finds Rare Variants Linked to Heart Disease in 17 Genes
Mount Sinai Health System

Using an advanced artificial intelligence tool, researchers at the Icahn School of Medicine at Mount Sinai have identified rare coding variants in 17 genes that shed light on the molecular basis of coronary artery disease (CAD), the leading cause of morbidity and mortality worldwide. The discoveries, detailed in the June 11 online issue of Nature Genetics, reveal genetic factors impacting heart disease that open new avenues for targeted treatments and personalized approaches to cardiovascular care. The investigators used an in silico, or computer-derived, score for coronary artery disease (ISCAD) that holistically represents CAD, as described in a previous paper by the team in The Lancet. The ISCAD score incorporates hundreds of different clinical features from the electronic health record, including vital signs, laboratory test results, medications, symptoms, and diagnoses. To build the score, they trained machine learning models on the electronic health records of 604,914 individuals

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This news release is embargoed until 10-Jun-2024 5:00 PM EDT Released to reporters: 4-Jun-2024 2:00 PM EDT

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Newswise: Intervention Aims to Improve Cardiovascular Health for South Asian Populations
Released: 10-Jun-2024 11:05 AM EDT
Intervention Aims to Improve Cardiovascular Health for South Asian Populations
University of Utah Health

People from South Asian countries tend to develop heart disease 10 years earlier than other populations. Kevin Shah, MD, is working to change that.

Newswise: Valentin Fuster, MD, PhD, Received 2024 Distinguished Award From European Society for Clinical Investigation (ESCI)
Released: 10-Jun-2024 7:00 AM EDT
Valentin Fuster, MD, PhD, Received 2024 Distinguished Award From European Society for Clinical Investigation (ESCI)
Mount Sinai Health System

President of Mount Sinai Fuster Heart Hospital given top honor for his scientific excellence and successful global education initiatives on cardiovascular disease

Newswise: High Blood Pressure in the Hospital: What Doctors Should Know
Released: 6-Jun-2024 3:05 PM EDT
High Blood Pressure in the Hospital: What Doctors Should Know
University of Utah Health

A new statement from the American Heart Association recommends a much more conservative approach to treating high blood pressure in acute care.

Newswise: UTSW studies clarify link between exercise, risk of heart disease
Released: 6-Jun-2024 11:05 AM EDT
UTSW studies clarify link between exercise, risk of heart disease
UT Southwestern Medical Center

Exercising at a high level doesn’t affect the progression of calcium buildup in the arteries, even among older athletes such as marathoners who tend to have higher coronary artery calcium (CAC) scores, according to new research from UT Southwestern Medical Center. But a longer duration of exercise is associated with higher CAC.

Released: 6-Jun-2024 10:05 AM EDT
Regenerating Damaged Heart Cells
Ann and Robert H. Lurie Children's Hospital of Chicago

Scientists from Stanley Manne Children’s Research Institute at Ann & Robert H. Lurie Children’s Hospital of Chicago have discovered a way to regenerate damaged heart muscle cells in mice, a development which may provide a new avenue for treating congenital heart defects in children and heart attack damage in adults, according to a study published in the Journal of Clinical Investigation.

Newswise: Cleveland Clinic-Led Study Links Sugar Substitute to Increased Risk of Heart Attack and Stroke
3-Jun-2024 3:05 PM EDT
Cleveland Clinic-Led Study Links Sugar Substitute to Increased Risk of Heart Attack and Stroke
Cleveland Clinic

 Cleveland Clinic researchers found higher amounts of the sugar alcohol xylitol are associated with increased risk of cardiovascular events like heart attack and stroke.

Newswise: Study reveals how 'forever chemicals' may impact heart health in older women
Released: 5-Jun-2024 10:05 AM EDT
Study reveals how 'forever chemicals' may impact heart health in older women
College of Agricultural, Consumer and Environmental Sciences, University of Illinois Urbana-Champaign

New research from the University of Illinois Urbana-Champaign has linked multiple types of per- and polyfluoroalkyl substances (PFAS, also known as “forever chemicals”) with increased risk of cardiovascular diseases in postmenopausal women. Specifically, the study reveals how PFAS chemicals interact with pro-inflammatory pathways in older women, providing potential explanations for the increased risk.

Released: 4-Jun-2024 11:05 AM EDT
Comparative Study on Dual vs Single Cardioversion for Atrial Fibrillation in Obese Patients
Ochsner Health

A team of Ochsner Health cardiologists recently published an article in the Journal of the American Medical Association (JAMA) Cardiology comparing two treatment strategies for patients with atrial fibrillation and obesity.

Released: 3-Jun-2024 4:05 PM EDT
Research shows GLP-1 receptor agonist drugs are effective but come with complex concerns
University of Chicago Medical Center

Studies from multiple UChicago experts show that while GLP-1RA drugs are extremely effective for weight loss and Type 2 diabetes treatment, there's no one-size-fits-all solution and physicians and patients have to consider issues like cost and side effects.

Released: 3-Jun-2024 7:05 AM EDT
Fewer than 1 in 4 patients receive dietary counseling after a heart attack
Michigan Medicine - University of Michigan

Although diet is the leading contributor to premature death from heart disease in the United States, fewer than one-quarter of people who undergo major heart events receive dietary counseling in the aftermath, a study finds. The reason for such a low rate, researchers suggest, may be a lack of time for providing the counseling or expertise in this area by clinicians.

Released: 3-Jun-2024 4:05 AM EDT
Jejum intermitente aumenta o risco de doença cardíaca?
Mayo Clinic

Há muitos anos, pessoas têm utilizado o jejum intermitente para perder quilos indesejados, enquanto outras jejuam por razões religiosas. A tendência popular da dieta é geralmente segura, mas alguns estudos sugerem que comer com restrição de tempo pode causar problemas cardíacos.

29-May-2024 9:00 AM EDT
Telemedicine may increase endocrinology care access for under-resourced patients with diabetes and heart disease
Endocrine Society

Widespread availability of telemedicine during the pandemic led to more equitable access to endocrinology care for patients with type 2 diabetes and heart disease, according to a study being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

29-May-2024 9:00 AM EDT
Two medication classes reduced cardiovascular and liver events in people with type 2 diabetes
Endocrine Society

GLP-1 receptor agonists (GLP-1s) and SGLT-2 inhibitors lower the risk of major cardiovascular events like heart attacks and severe liver complications compared to other diabetes treatments, according to data being presented Sunday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

29-May-2024 9:00 AM EDT
Hot flashes in menopausal women may signal increased risk for heart and metabolic issues
Endocrine Society

Women experiencing moderate-to-severe vasomotor symptoms face a three times greater risk for metabolic-dysfunction-associated steatotic liver disease (MASLD) compared to those with mild symptom severity, according to research being presented Monday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.

29-May-2024 9:00 AM EDT
Risk for heart attack and stroke increases in people with obesity for a decade or more
Endocrine Society

People under age 50 have a greater risk for heart attack or stroke if they’ve lived with obesity for 10 years, according to industry-sponsored research being presented Saturday at ENDO 2024, the Endocrine Society’s annual meeting in Boston, Mass.



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