New research from the Monell Center suggests that a little-understood sensory cell may protect the vulnerable olfactory epithelium by detecting and initiating defenses against viruses, bacteria, and other potentially harmful invaders.
A new collaboration grant to Discovery BioMed and the Monell Center will support development of next-generation screening technologies to identify bitter taste blockers. The work will advance health by improving the taste and acceptability of nutritious plant-based foods and increasing patient willingness to take life-saving oral medicines.
The Monell Center and Jefferson (Philadelphia University and Thomas Jefferson University) announce the signing of a one-year Agreement of Cooperation, outlining how the two institutions will collaborate over the next year to develop joint scientific programs and clinical opportunities to advance their shared mission of improving human health.
By educating physicians about unique properties of the olfactory system, Monell scientist Pamela Dalton, PhD, MPH, seeks to increase understanding of stigmas associated with incontinence
The Monell Center, in partnership with the University of Florida Center for Smell and Taste and the Rocky Mountain Taste and Smell Center at the University of Colorado School of Medicine, will host an interdisciplinary two-day conference in November 2018 to establish a roadmap for treatment-focused research on smell and taste disorders. The “Identifying Treatments for Taste and Smell Disorders” meeting will include sessions focused on the science of sensory disorders and their treatment and also on patient education.
Lee O’Neill, MBA, has been appointed as the new Director for Finance & Administrative Services for the Monell Chemical Senses Center, effective May 1, 2018. He succeeds John K.T. Tran, MS, CRA, who is retiring after serving 30 years as Monell’s Finance Director.
February 27 is Anosmia Awareness Day. Many people don’t appreciate what it means to be unable to smell. As someone with congenital anosmia, I know first-hand what it feels like to go through each day without the sense of smell.
Research from the Monell Center documented wide individual differences to the taste of the life-saving HIV medication Kaletra and identified genetic sources of the taste variation. The findings suggest that the growing field of pharmacogenetics should assess the sensory response to medicines to promote medication compliance and treatment success.
Leadership at Jefferson and the Monell Center announced today the signing of a non-binding Letter of Intent (LOI) to move forward with discussions of merging the two organizations.
A significant technological advance from the Monell Center now allows scientists to identify the complete set of genes in any type of taste receptor cell. The technology will help identify precisely how each cell carries out its specific function.
A new study from the Monell Center and collaborating institutions advances understanding of how stem cells on the tongue grow into the different types of mature taste cells that detect either sweet, salty, sour, bitter, or umami. The findings may someday allow scientists to treat taste disorders, characterize new taste qualities, or even fine-tune a person’s taste perception to encourage healthier eating.
A new study of older U.S. adults from the Monell Center and collaborating institutions reports that a woman’s social life is associated with how well her sense of smell functions. The study found that older women who do less well on a smell identification task also tend to have fewer social connections.
A study from the Monell Center and collaborators provides new insight into the causes of trimethylaminura (TMAU), a genetically-transmitted metabolic disorder that leads to accumulation of a chemical that smells like rotting fish. Previously attributed solely to mutations in the FMO3 gene, the study identifies additional genes that may contribute to TMAU. The findings indicate that genetic testing to identify FMO3 mutations may not be sufficient to identify all underlying causes of TMAU.
A new grant from the Robert J. Kleberg, Jr. and Helen C. Kleberg Foundation will allow Monell scientists and collaborators to confirm initial findings of a unique odor pattern for ovarian cancer. The multi-disciplinary team will use the information to customize a portable screening device that can diagnose the deadly disease at early, treatable stages.
New research from the Monell Center reveals that children begin using olfactory information to help guide their responses to emotionally-expressive faces at about age five. The findings advance understanding of how children integrate different types of sensory information to direct their social behavior.
Does eating good-tasting food make you gain weight? Despite the common perception that good-tasting food is unhealthy and causes obesity, new research from the Monell Center using a mouse model suggests that desirable taste in and of itself does not lead to weight gain.
The Monell Center announced today that it has received a $345,000 grant from the Bill & Melinda Gates Foundation. The grant supports an innovative global health research project titled, "Developing Novel Pediatric Formulation Technologies for Global Health: Human Taste Assays."
New research from the Monell Center finds that oral perceptions of coldness and carbonation help to reduce thirst. The findings could guide sensory approaches to increase fluid intake in populations at risk for dehydration, including the elderly, soldiers, and athletes.
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