Credit: Tamir Gonen, Janelia Farm Research Campus/HHMI
Images of lysozyme microrystals. (A) Light micrograph showing
524 lysozyme microcrystals (three examples indicated by arrows) in comparison with
525 larger crystals of the size normally used for X-ray crystallography. Scale bar is 50
526 μm. (B) Lysozyme microcrystals visualized in over-focused diffraction mode on the
527 cryo-EM prior to data collection. The length and width of the crystals varied from 2
528 to 6 μm with an estimated thickness of ~0.5 to 1 μm. Scale bar is 1 μm.