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Women with BRCA1 Gene Mutation at Higher Risk of Deadly Uterine Cancer

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Women who carry the BRCA1 gene mutation that dramatically increases their risk of breast and ovarian cancers are also at higher risk for a lethal form of uterine cancer, according to a study led by a Duke Cancer Institute researcher.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 8-Jul-2016 6:00 AM EDT

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Reporter Needed to Cover New 'Fast Pitch' Service from Newswise

Newswise Fast Pitch is the first service to invite reporters and communications people to meet via video conference and pitch story ideas. Reporters are highly satisfied with the results.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 7-Jul-2016 6:00 AM EDT

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Ovarian Cancer Study Uncovers New Biology

In what is believed to be the largest study of its kind, scientists at The Johns Hopkins University and the Pacific Northwest National Laboratory led a study that examined the proteomes of 169 ovarian cancer patients to identify critical proteins expressed by their tumors. By integrating their findings with the tumors’ genetic data — the cancer genome — the investigators report the potential for new insights into the progress of the most malignant form of the disease.

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Ovarian Cancer Study Provides Painstaking Look at Inner Workings of Tumors

Scientists have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors. The achievement illustrates the power of combining genomic and proteomic data – an approach known as proteogenomics – to yield a more complete picture of the biology of ovarian cancer.

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Progesterone in Botanicals Could Aid Women’s Health

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The University of Illinois at Chicago has received a five-year, $1.225 million federal grant to discover progesterone-like compounds from commonly consumed botanicals and learn how the hormones can aid women’s health.

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3D Printed Kidney Helps Doctors Save Woman's Organ During Complicated Tumor Removal

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Doctors and scientists at Intermountain Medical Center in Salt Lake City printed and used a 3D kidney to help save a patient's organ during a complicated tumor-removal procedural.

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Cardiac Rehab: One Size Does Not Fit All; Canadian Study Reveals ‘Who’ Benefits Most

Toronto Rehab researchers have discovered a new approach for determining which patient populations benefit most from cardiac rehabilitation.

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Scientists Measure How Baby Bump Changes the Way Women Walk

Movie sets are normally the home of three-dimensional motion caption systems, but researchers used the same video recording system in a lab to measure the way pregnant women walk. This is the first research study to use 3D motion capture to create a biomechanical model of pregnant women. The results verify the existence of the "pregnancy waddle" and should enable future studies on how to make everyday tasks safer and more comfortable for pregnant women.

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Many Women with Early Stage Breast Cancer Experience Functional Decline After Initiating Treatment

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In a study of older women with newly diagnosed stage I to III breast cancer, approximately one in five lost the ability to complete some of the basic tasks necessary for independent living within one year of initiating treatment. Within 12 months, 34 of the 184 patients developed functional decline and seven died.

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Study Shows Women Lack Confidence in Maternity Care Providers

A new University of Michigan study shows that women are even more afraid of childbirth than previously thought—and are as concerned about their health care providers and their place of birth as they are about pain or complications.

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Georgetown Institute Launches Real-Time Study of Smartphone Fertility App Use

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In what is believed to be the first study of its kind, researchers at Georgetown University Medical Center’s Institute for Reproductive Health (IRH) are recruiting as many as 1,200 women to study a smartphone app that calculates a woman’s chance for pregnancy on a daily basis.

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Cross Talk Between Hormone Receptors Has Unexpected Effects

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Although the estrogen receptor is considered dominant in breast cancer, the progesterone receptor assumes control when both receptors are present and exposed to estrogens and progestins. Then, the progesterone receptor drives estrogen receptor activity. Treating tumor-bearing mice with an estrogen antagonist and a progestin antagonist caused rapid tumor regression.

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Zika Virus Alerts May Have Prompted Uptick in Abortion Requests in Latin America

Pregnant women in Latin American countries were more likely to seek an abortion after receiving health alerts about Zika virus, according to a study co-authored by Princeton University researchers and published in the New England Journal of Medicine.

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Index Could Help Identify Women at Risk for Rapid Bone Loss

Researchers have developed an index to better predict which women may experience faster bone loss across the menopause transition, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Mount Sinai’s Discovery of an Epigenetic Regulator of Tumorigenesis Suggests New Strategies Against Lethal Forms of Breast Cancer

Mount Sinai scientists have identified a previously unknown mechanism by which a protein called CBX8 promotes tumor growth in the most lethal forms of breast cancer. The study, published today in the journal Cell Reports, underscores the need for cancer researchers to pay more attention to “epigenetic” factors, meaning chemical and biological processes that control gene expression without changing the underlying DNA sequence of the cells that are running amok.

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How a Woman with Amnesia Defies Conventional Wisdom About Memory

She no longer recognizes a Van Gogh, but can tell you how to prepare a watercolor palette. The sharp contrasts in an amnesia patient’s memory profile suggest conventional wisdom about how the brain stores knowledge is incorrect.

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Some Plant-Based Therapies Associated with Modest Improvement in Menopausal Symptoms

An analysis of more than 60 studies suggests that some plant-based therapies are associated with modest reductions in the frequency of hot flashes and vaginal dryness but no significant reduction in night sweats, according to a study appearing in the June 21 issue of JAMA.

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Telephones Can Bring Cancer Genetic Counseling to Rural Women

For women in rural communities, traveling to meet in person with cancer genetic counselors can be time-consuming and expensive. Now, a new study shows that getting cancer genetic counseling over the phone can be just as good as getting the same counseling in person. The work, led by Anita Kinney, PhD, RN, at The University of New Mexico Comprehensive Cancer Center, was published in the Journal of Clinical Oncology.