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Cloning, genes, genetic sequencing, genetic, Health, Medicine, Genome, Human Genome, DNA, Proteins, Biology, Science, Genomics, Engineering, Biomedical Engineering, E. Coli, Bacteria, Animals, Plants, Microbes, LASSO probes, LASSO , Microbiome, human microbiome, Pharma, Pharmaceuticals, Drugs, Precision Medicine, Rutgers University, Rutgers, New Jersey, NJ

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A reporter's PressPass is required to access this story until the embargo expires on 26-Jun-2017 11:00 AM EDT

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A reporter's PressPass is required to access this story until the embargo expires on 28-Jun-2017 5:00 AM EDT

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Cancer Cells May Streamline Their Genomes in Order to Proliferate More Easily

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Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. The study, conducted in both human and mouse cells, shows that cancer genomes lose copies of repetitive sequences known as ribosomal DNA. While downsizing might enable these cells to replicate faster, it also seems to render them less able to withstand DNA damage.

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Biology, Biotechnology, Developmental Biology, Regenerative Medicine, gastrointestinal disease, Colon, Cell Biology, Genetics, human pluripotent stem cells, CELL STEM CELL, Cell Press , Science, Research, Cincinnati Children's Hospital Medical Center, National Institutes , Pediatrics, press release, press release distribution, Children

Lab Grown Human Colons Change Study of GI Disease

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Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem Cell. The study is believed to be the first time human colon organoids have been successfully tissue engineered in this manner, according to researchers who led the project.

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HIV, AIDS, Cytomegalovirus, Mother To Child Transmission, Infant, CMV, brain damage infants, Fetal Growth, Liver Damage, lung damage, spleen damage, Hearing Loss, HIV Positive Women

HIV-Positive Women with Cytomegalovirus Likelier to Pass Virus That Causes AIDS to Infant

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HIV-positive women with CMV in their urine at the time of labor and delivery are more than five times likelier than HIV-positive women without CMV to transmit HIV to their infants. The research also found that they are nearly 30 times likelier to transmit CMV to their infants.

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What Percentage of ALS Is Genetic?

Up to 90 percent of people with amyotrophic lateral sclerosis (ALS) report that they have no family history of the disease. Now, new research has found approximately 17 percent of such ALS cases may be caused by a gene mutation, according to a study published in the June 21, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology.

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A reporter's PressPass is required to access this story until the embargo expires on 28-Jun-2017 2:00 PM EDT

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heterochromatin, Genome, Cell Biology

Researchers Find New Mechanism for Genome Regulation

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The same mechanisms that separate mixtures of oil and water may also help the organization of an unusual part of our DNA called heterochromatin, according to a new study by Berkeley Lab researchers. They found that liquid-liquid phase separation helps heterochromatin organize large parts of the genome into specific regions of the nucleus. The work addresses a long-standing question about how DNA functions are organized in space and time, including how genes are silenced or expressed.

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Next-generation sequencing panel , pediatric cancers, Comprehensive DNA and RNA Pediatric Cancer Panel

Children’s Hospital Los Angeles Launches OncoKidsSM – a Comprehensive DNA and RNA Pediatric Cancer Panel

Today, a team of investigators at Children’s Hospital Los Angeles launched OncoKidsSM, a next-generation sequencing-based panel specifically designed for pediatric cancers.







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