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Researchers Unravel a Link Between a Genetic Mutation and Autistic Behaviors – and Then Find a Way to Undo It

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Scientists at the University at Buffalo have identified the mechanisms behind a genetic mutation that produces certain autistic behaviors in mice, as well as therapeutic strategies to restore normal behaviors.

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A reporter's PressPass is required to access this story until the embargo expires on 4-Jun-2015 12:00 PM EDT

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Trending Stories Report for 28 May 2015

Trending news releases with the most views in a single day. Topics include: income inequality, climate change, genetics, cancer, precision medicine, medical imaging, schizophrenia, research funding, molecular biology and skin cancer.

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Study Shows Treatment for Genetically Caused Emphysema Is Effective

A landmark clinical study in the Lancet provides convincing evidence that a frequently overlooked therapy for genetically-caused emphysema is effective and slows the progression of lung disease.

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A reporter's PressPass is required to access this story until the embargo expires on 29-May-2015 2:00 PM EDT

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Malfunction in Cancer-Preventing NONO Protein Worsens Effects of UV Radiation

Researchers have uncovered a new molecular mechanism - a function of the NONO protein - whereby cells protect their genome from the detrimental effect of UV radiation and govern DNA replication in cellular mitosis. A recent study investigates what happens when this molecular mechanism malfunctions.

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Stress Triggers Key Molecule to Halt Transcription of Cell’s Genetic Code

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Researchers at the Stowers Institute have shown that a molecule called elongin A assists with transcription.

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Researchers Discover Surprisingly Wide Variation Across Species in Genetic Systems That Influence Aging

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A new Iowa State University study focusing on insulin signaling uncovered surprising genetic diversity across reptiles, birds and mammals. Scientists previously assumed the process remained much the same throughout the animal kingdom, but the new research shows that the genetic pathways in reptiles evolved to include protein forms not observed in mammals.

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GW Researcher Finds Differences in Brain Expression of RORA Gene May Contribute to Sex Bias in Autism

Valerie Hu, Ph.D., professor of biochemistry and molecular medicine at the George Washington University School of Medicine and Health Sciences, has found an important sex-dependent difference in the level of RORA protein in brain tissues of males and females. Specifically, females without autism have a slightly higher level of RORA in the frontal cortex of the brain than males without autism, while the levels of the protein are comparably lower in the brain of both males and females with autism.