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Friction Harnessed by Proteins Helps Organize Cell Division

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A football-shaped structure, known as the mitotic spindle, makes cell division possible for many living things. This piece of cellular architecture, responsible for dividing up genetic material, is in constant flux. The filaments that form it grow and shrink, while motor-like molecules burn energy pushing them about. To ensure the complex process proceeds in an orderly fashion, molecular fasteners pin the filaments together in certain places, and new research in Tarun Kapoor’s Laboratory of Chemistry and Cell Biology helps explain how they do it.

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Mutant Protein in Muscle Linked to Neuromuscular Disorder

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Spinal and bulbar muscular atrophy (SBMA) is a rare inherited neuromuscular disorder characterized by slowly progressive muscle weakness and atrophy. In a new study published in the April 16, 2014 online issue of Neuron, a team of scientists at the University of California, San Diego School of Medicine say novel mouse studies indicate that mutant protein levels in muscle cells are fundamentally involved in SBMA, suggesting an alternative and promising new avenue of treatment.

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Finding the Switch: Researchers Create Roadmap for Gene Expression

In a new study, researchers from North Carolina State University, UNC-Chapel Hill and other institutions have taken the first steps toward creating a roadmap that may help scientists narrow down the genetic cause of numerous diseases.

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Bio-Engineered Vaginas, How Do They Work? UPDATE: Watch Pre-Recorded Q&A

Newswise hosts the first live, interactive virtual event for major research finding for journalists. Newswise and Wake Forest Baptist Medical Center are collaborating to offer direct access to the investigator via Newswise Live, an interactive virtual event.

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Bio-Engineered Vaginas, How Do They Work? Researcher Takes Your Questions on Newswise Live Event

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Splice Variants Reveal Connections Among Autism Genes

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A team of researchers from the University of California, San Diego School of Medicine and the Center for Cancer Systems Biology (CCSB) at the Dana-Farber Cancer Institute has uncovered a new aspect of autism, revealing that proteins involved in autism interact with many more partners than previously known.

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