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Smoking Cessation, Electronic Cigarettes, e-cigarette, Smoking

E-Cigarettes: Harm Reduction or ‘Gateway’ to New Smokers?

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Smoking is an issue that has been at the heart of public health concerns for decades, with many efforts to restrict tobacco sales, tax cigarettes and sometimes hard-hitting campaigns to get people to quit smoking. But if the tobacco control community has long agreed on the harms of smoking, the place of reducing, rather than eliminating, harm has been hotly contested.

Medicine

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Cancer, Dr. Robert Kyle, Dr. S. Vincent Rajkumar, Mayo Clinic, Medical Research, MGUS, Minnesota News Releases, Monoclonal Gammopathy of Undetermined Significance, Multiple Myeloma, New England Journal Of Medicine, news releases

Patients with Blood Cancer Precursor at Risk of Developing Cancer Even After 30 Years

Patients with monoclonal gammopathy of undetermined significance are at risk of progressing to multiple myeloma or a related cancer ─ even after 30 years of stability. These are the findings of a study by Mayo Clinic researchers published in the Wednesday, Jan. 17, issue of the New England Journal of Medicine.

Medicine

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HIV, AIDS, CURE, Antibodies, Treatment, Prevention

Multivalent Antibodies Show Effectiveness for HIV Prevention and Promise for Treatment and Cure

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Recent studies testing multivalent combinations of three broadly neutralizing antibodies, or bnAbs, have yielded promising results in animal models of HIV prevention. Two investigators at the University of North Carolina at Chapel Hill describe the potential of bnAbs to inform HIV prevention, treatment and cure strategies in a recent article in the New Journal of Medicine.

Medicine

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mieloma múltiple, gammapatía monoclonal de significado incierto, GMSI, MGUS, Cancer

Pacientes Que Tienen Precursor De Cáncer Sanguíneo Corren Riesgo De Desarrollar Cáncer Incluso Después De 30 años

Los pacientes con gammapatía monoclonal de significado incierto corren más riesgo de avanzar hacia mieloma múltiple u otro cáncer afín, incluso después de 30 años de estabilidad.

Medicine

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Scleroderma, University Of Virginia, UVA, University of Virginia Cancer Center, UVA Cancer Center, NCI-designated cancer centers, Cancer, Karen Ballen, University of Virginia School of Medicine, UVA School of Medicine, autoimmune disorder, Autoimmune Disease, skin, Skin Disorder, skin thickening, skin hardening, New Treatments, Medical Research, treatment f

Scleroderma: Study Suggests Hope for Longer Life for Patients with Rare Autoimmune Disorder

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The approach could represent the first new treatment to improve survival in patients with severe scleroderma in more than four decades.

Medicine

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IVF, In Vitro Fertilization, Fertility, Infertility, Babies, embryo freezing

Frozen Embryos Result in Just as Many Live Births in IVF

Freezing and subsequent transfer of embryos gives infertile couples just as much of a chance of having a child as using fresh embryos for in vitro fertilization (IVF), research from Ho Chi Minh City, Vietnam, and Adelaide, Australia has found.

Medicine

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Hematapoietic, Stem Cell, Transplant, Gene Therapy, New England Journal Of Medicine, Uc Davis

UC Davis Researcher Urges Caution on Engineered Stem Cells

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In a commentary published in the Jan. 4 issue of the New England Journal of Medicine, UC Davis researcher William Murphy expressed cautious optimism about efforts to genetically engineer hematopoietic stem cells (HSCs) to temporarily resist cell death during transplantation. While these gene therapy approaches could dramatically improve patient outcomes, Murphy argues that their risks must be carefully studied in diverse models.

Medicine

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Scleroderma, auto-immune disease, Stem Cell Transplantation

Study Shows Stem Cell Transplant Is Better Than Drug Therapy for Scleroderma

Duke Health researchers, publishing in the Jan. 4 issue of the New England Journal of Medicine, found significantly improved survival among patients with a severe form of scleroderma who underwent chemotherapy, whole body radiation and a stem cell transplant. Patients also had less need for immune suppressant drugs after transplant.

Medicine

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Mark Yarchoan, Alexander Hopkins, Elizabeth Jaffee, checkpoint inhibitors, Immunotherapy, mutational burden

More Tumor Mutations Equals Higher Success Rate With Cancer Immunotherapy Drugs

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The "mutational burden," or the number of mutations present in a tumor's DNA, is a good predictor of whether that cancer type will respond to a class of cancer immunotherapy drugs known as checkpoint inhibitors, a new study led by Johns Hopkins Kimmel Cancer Center researchers shows. The finding, published in the Dec. 21 New England Journal of Medicine, could be used to guide future clinical trials for these drugs.

Medicine

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ventricular tachycardia, Radiation Therapy

Deadly Heart Rhythm Halted by Noninvasive Radiation Therapy

Radiation therapy often is used to treat cancer patients. Now, doctors at Washington University School of Medicine in St. Louis have shown that radiation therapy — aimed directly at the heart — can be used to treat patients with a life-threatening heart rhythm. They treated five patients with irregular heart rhythms, called ventricular tachycardia, who had not responded to standard treatments. The therapy resulted in a dramatic reduction in the number of ventricular tachycardia episodes.







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