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Pediatrics, Pediatric Oncology, Immunotherapy, CAR T cells, All, Acute Lymphoblastic Leukemia

In Clinical Trials, CAR T Cell Immunotherapy Continues to Yield Complete Responses in Children & Young Adults with Relapsed and Refractory Leukemia

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A highly innovative, personalized cell-based treatment for a high-risk form of the most common childhood cancer continues to move through clinical trials. Pediatric oncologists from Children’s Hospital of Philadelphia (CHOP) today reported new results using T cell immunotherapy against relapsed or refractory acute lymphoblastic leukemia (ALL).

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Hematology, Oncology, Pediatrics, aplastic anemia, Bone Marrow Transplant

Rainbow Babies & Children’s Experts to Present Pediatric Focused Data at 58th American Society of Hematology Annual Meeting

Ashish Gupta, MBBS, MPH, a pediatric hematology fellow, will share results from one of the largest quality controlled retrospective studies of children with acquired aplastic anemia. The data makes a compelling case for the pediatric hematology community to revisit the current treatment algorithm for this rare disease.

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Hemophilia, Gene Therapy, Hemophilia B, Clinical Trial, clotting factor IX, Children's Hospital Of Philadelphia

After One Dose of Gene Therapy, Hemophilia B Patients Maintain Near-Normal Levels of Clotting Factor

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Researchers are reporting the highest and most sustained levels to date of an essential blood-clotting factor IX in patients with the inherited bleeding disorder hemophilia B. After receiving a single dose of an experimental gene therapy in a clinical trial, patients with hemophilia produced near-normal levels of clotting factor IX, allowing them to stop clotting factor infusions and to pursue normal activities of daily life without disabling bleeding episodes.

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annual meeting 2017, Tech-Con, Dr. Samer Nashef, Press Conference, Scientific Sessions, Mycobacterium Chimaera Infections, Scientific Research, Cardiothoracic Surgery

Media Advisory: Save the Date for STS Annual Meeting

Credentialed press representatives are invited to attend The Society of Thoracic Surgeons 53rd Annual Meeting and Exhibition.

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ISPOR Annual European Congress, Healthcare Access, Healthcare Policy, health technology assessment, HTA, differential pricing, medical innovation, healthcare cost

ISPOR 19th Annual European Congress Drew Key Stakeholders and Thought Leaders to Discuss Access to Medical Innovations

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The International Society for Pharmacoeconomics and Outcomes Research recently concluded its 19th Annual European Congress in Vienna, Austria. More than 4,700 delegates—stakeholders from all sectors of health care, including health ministries and government offices, health technology assessment bodies, public and private payers, researchers and academics, patients and patient advocates—representing 89 countries convened on 29 October through 2 November 2016 to discuss access to medical innovations in Europe.

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ISPOR Annual European Congress, ISPOR Awards

Best Podium and Poster Presentations Awarded at ISPOR 19th Annual European Congress

The International Society for Pharmacoeconomics and Outcomes Research recognized the Best Podium Presentation and Best Poster Presentation Awardees at its 19th Annual European Congress in Vienna, Austria.

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Tighter Blood Pressure Control May Save More Than 100,000 Lives Each Year in the U.S.

• New research estimates the projected lives that would be saved if patients at high risk of cardiovascular disease underwent intensive blood pressure lowering. • The findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Coordination of Care Benefits Patients with Kidney Disease and Reduces Medical Costs

• Multi-disciplinary care—or coordination of care among different clinicians and specialists—improves the health of patients with kidney disease and reduces costs compared with usual care. • Results from the study will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Short and Poor Quality Sleep May Have Negative Effects on Kidney Function

• In a study of patients with chronic kidney disease, each additional hour of nighttime sleep was linked with a 19% lower risk of developing kidney failure. • There was also a significant association between sleep quality and kidney failure risk. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Scientists Get Closer to Developing Bioartificial Kidney

• Researchers have developed a key component needed to create a bioartificial kidney. • The advance will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Simple Saliva Test May Help Clinicians Diagnose Kidney Disease

• A dipstick test for salivary urea nitrogen was accurate for diagnosing kidney disease in adults in Malawi, Africa. • Results of the test also helped predict patients’ risk of early death. • The test will be described at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Last-Line Antibiotics Are Failing

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On the occasion of the 9th European Antibiotic Awareness Day, the European Centre for Disease Prevention and Control (ECDC) is releasing its latest EU-wide data on antibiotic resistance and antibiotic consumption.

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Reflux and Ulcer Medications Linked to Kidney Stones and Chronic Kidney Disease

• Individuals who took proton pump inhibitors or histamine receptor-2 blockers for heartburn, acid reflux, or ulcers had elevated risks of developing kidney stones. • In individuals without acute kidney injury, proton pump inhibitors were linked with a higher risk of developing chronic kidney disease or kidney failure compared with histamine receptor-2 blockers. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Program May Help Increase Numbers of Live Kidney Donors

• The Live Donor Champion program increased knowledge of live donation and comfort approaching others about live donation, and it boosted live donor referrals. • The program will be described at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Method to Create Kidney Organoids From Patient Cells Provides Insights on Kidney Disease

• Scientists have developed a method to coax human pluripotent stem cells to mature into cells that go on to form the functional units of the kidney. • The team has demonstrated how the method can be used to study human kidney diseases. • The research will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Smoking May Block Some of the Benefits of Kidney Disease Medications

• In a study of patients with chronic kidney disease, nonsmokers and smokers who successfully quit had slower worsening of their kidney function than those who were unsuccessful at quitting. • Cigarette smoking partially negated the kidney-protective effects of patients’ medications. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Research Provides Insights on the Link Between Kidney Damage and Cognitive Impairment

• Kidney damage was linked with worse performance on tests of global cognitive function, executive function, memory, and attention. • Kidney damage may also be linked with structural abnormalities in the brain. • Research that uncovered these findings will be presented at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.

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Wayne State University, Henry Ford Hospital, Nephrology, End Stage Renal Disease, Chronic Kidney Disease, ESRD, CKD

Wayne State and Henry Ford Present Findings on Reducing Hospital Visits for Patients with ESRD and CKD

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On November 17, 2016, a Wayne State University doctoral student, Matthew Jasinski, will present results from his dissertation at the Annual Meeting of the American Society of Nephrology in Chicago. The study demonstrates the value of proactive identification of and family psychoeducation about cognitive impairment in patients with End State Renal Disease or Chronic Kidney Disease (ESRD/CKD). A team from Henry Ford Hospital led by Mark Ketterer, Ph.D., a clinical psychologist in the Department of Behavioral Health Services, collaborated with Jasinski, a Wayne State Department of Psychology graduate student, and Mark Lumley, Ph.D., professor of psychology at Wayne State, to conduct a clinical trial that sought to reduce the number of 30-day hospital readmissions by educating patients with ESRD and their family members about the patient’s health needs.

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HIV, AIDS, Hiv Aids, HIV and AIDS, Center for AIDS Research, Global Health

International HIV Symposium Comes to Birmingham

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Scientists from around the world will gather at UAB in December to focus on HIV research and women, particularly collaborative research on women living with HIV and those at risk.

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Telemedicine Program Provides Life-Saving Kidney Care to Patients in Rural Areas

• A telemedicine program that partners a national dialysis provider with a rural hospital in Kentucky can surmount traditional barriers to deliver kidney care to rural hospitals. • The program will be described at ASN Kidney Week 2016 November 15–20 at McCormick Place in Chicago, IL.







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