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UT Southwestern Researchers Uncover New Brain Pathways for Understanding Type 2 Diabetes and Obesity

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Researchers at UT Southwestern Medical Center have identified neural pathways that increase understanding of how the brain regulates body weight, energy expenditure, and blood glucose levels – a discovery that can lead to new therapies for treating Type 2 diabetes and obesity

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Vanderbilt Study Examines Bacteria’s Ability to Fight Obesity

Bacteria that produce a therapeutic compound in the gut inhibit weight gain, insulin resistance and other adverse effects of a high-fat diet in mice, Vanderbilt University investigators have discovered.

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Inadequate Mental Health Care for Blacks with Depression and Diabetes, High Blood Pressure

A new study in General Hospital Psychiatry confirms that Blacks with depression plus another chronic medical condition, such as Type 2 diabetes or high blood pressure, do not receive adequate mental health treatment.

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Joslin Scientists Create the First IPS Cells to Offer Human Model of Insulin Resistance

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Scientists at Joslin Diabetes Center now have created the first iPSCs that offer a human model of insulin resistance, a key driver of type 2 diabetes.

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Manipulation of Key Protein’s Action in the Brain Holds Potential for Development of Drugs to Fight Obesity and Diabetes

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A protein that controls when genes are switched on or off plays a key role in specific areas of the brain to regulate metabolism, UT Southwestern Medical Center researchers have found.

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Low-Carb Diet Recommended for Diabetics

A new study suggests that low carbohydrate diets should be the first point of attack in managing Type 1 and Type 2 diabetes.

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Researchers Find Mechanism That Clears Excess of a Pancreatic Protein Linked with Type 2 Diabetes

In people with Type 2 diabetes, a process called autophagy that prevents the accumulation of toxic forms of a protein called IAPP appears to not work properly, contributing to the destruction of beta cells. Beta cells play a key role in maintaining healthy blood sugar levels.

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Strategy Proposed for Preventing Diseases of Aging

Researchers at Washington University School of Medicine in St. Louis and elsewhere argue that medicine focuses too much on fighting diseases individually instead of concentrating on interventions that prevent multiple chronic diseases and extend healthy lifespan. They call for moving forward with strategies that have been shown to delay aging in animals. In addition to promoting a healthy diet and regular exercise, these strategies include manipulating molecular pathways that slow aging and promote healthy longevity.

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High-Salt Diet Doubles Threat of Cardiovascular Disease in People with Diabetes

People with Type 2 diabetes who eat a diet high in salt face twice the risk of developing cardiovascular disease as those who consume less sodium, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

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Researchers Discover New Link Between Obesity, Inflammation, and Insulin Resistance

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Study finds that the NBR1 protein plays a critical role in regulating obesity-induced inflammation that leads to metabolic disease. The findings suggest a new approach to targeting the inflammatory links between obesity and metabolic disease to prevent and treat type 2 diabetes.

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