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Joslin Scientists Find Direct Link Between Insulin Resistance in the Brain and Behavioral Disorders

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People with diabetes are more prone to anxiety and depression than those with other chronic diseases that require similar levels of management.

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New Views of Enzyme Structures Offer Insights Into Metabolism of Cholesterol, Other Lipids

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With the aid of X-ray crystallography, researchers at the University of Michigan have revealed the structures of two closely related enzymes that play essential roles in the body's ability to metabolize excess lipids, including cholesterol.

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NYU Study Successfully Screens for Diabetes at Dental Visits Using Oral Blood

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Now, a new study published in the American Journal of Public Health, confirms that using gingival crevicular blood (GCB) for hemoglobin A1c (HbA1c) testing produced values that were nearly identical to those obtained using finger stick blood (FSB), with a correlation of .991 between the two blood samples of 408 dental patients. Testing HbA1c is promoted by the American Diabetes Association (ADA) for diabetes diagnostic purposes and glycemic control monitoring.

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Shining New Light on Vascular Diseases in Diabetics

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Columbia Engineering Professor Andreas Hielscher is developing a novel technology that could improve diagnosis of peripheral arterial disease and make it easier to monitor patients. He’s won a $2.5 million 5-year grant from the National Heart, Lung, and Blood Institute to build and test a dynamic optical tomographic imaging system, which uses near-infrared light to map the concentration of hemoglobin in the body’s tissue and reveal how well blood is perfusing patients’ hands and feet.

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UVA Prevents Diabetic Heart Condition by Amplifying Effect of Exercise

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Magnifying a benefit of exercise in mice provided a “profound” protection from diabetic cardiomyopathy, a potentially deadly heart condition that affects many people with diabetes. The discovery demonstrates the power of exercise to prevent chronic health conditions and suggests that one day some benefits of exercise may come in a pill or bottle.

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Interventions Lower Diabetes Risk in Women who had Gestational Diabetes

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Women with a history of gestational diabetes face a heightened risk of developing Type 2 diabetes for years after giving birth, but intensive lifestyle intervention or a medication regimen can have a protective effect in this population, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Vitamin D Deficiency Linked More Closely to Diabetes than Obesity

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People who have low levels of vitamin D are more likely to have diabetes, regardless of how much they weigh, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism.

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Molecular Link between Obesity and Type 2 Diabetes Reveals Potential Therapy

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Researchers at University of California, San Diego School of Medicine have discovered that the inflammatory molecule LTB4 promotes insulin resistance, a first step in developing type 2 diabetes. What’s more, the team found that genetically removing the cell receptor that responds to LTB4, or blocking it with a drug, improves insulin sensitivity in obese mice. The study is published Feb. 23 by Nature Medicine.

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Researcher at Johns Hopkins Helps to Lead Discovery on Efficacy and Safety of Eylea, Lucentis and Avastin for Treating Patients with Diabetic Macular Edema

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A researcher from Johns Hopkins Medicine helped lead colleagues from across the country in a government-sponsored study by the Diabetic Retinopathy Clinical Research Network to discover that three drugs ― Eylea, Avastin and Lucentis ― used to treat diabetic macular edema are all effective. They also discovered that Eylea outperformed the other two drugs when vision loss was moderate to severe.

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Precision Medicine to Prevent Diabetes? Researchers Develop Personalized Way to Steer Prevention Efforts

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Researchers have just released a “precision medicine” approach to diabetes prevention that could keep more people from joining the ranks of the 29 million Americans with diabetes – using existing information like blood sugar levels and waist-to-hip ratios, and without needing new genetic tests.