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Strategy Proposed for Preventing Diseases of Aging

Researchers at Washington University School of Medicine in St. Louis and elsewhere argue that medicine focuses too much on fighting diseases individually instead of concentrating on interventions that prevent multiple chronic diseases and extend healthy lifespan. They call for moving forward with strategies that have been shown to delay aging in animals. In addition to promoting a healthy diet and regular exercise, these strategies include manipulating molecular pathways that slow aging and promote healthy longevity.

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High-Salt Diet Doubles Threat of Cardiovascular Disease in People with Diabetes

People with Type 2 diabetes who eat a diet high in salt face twice the risk of developing cardiovascular disease as those who consume less sodium, according to a new study published in the Endocrine Society’s Journal of Clinical Endocrinology & Metabolism (JCEM).

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Researchers Discover New Link Between Obesity, Inflammation, and Insulin Resistance

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Study finds that the NBR1 protein plays a critical role in regulating obesity-induced inflammation that leads to metabolic disease. The findings suggest a new approach to targeting the inflammatory links between obesity and metabolic disease to prevent and treat type 2 diabetes.

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One Injection Stops Diabetes in Its Tracks

Treatment reverses symptoms of type 2 diabetes in mice without side effects.

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Cholesterol-Lowering Drugs May Reduce Cardiovascular Death in Type 2 Diabetes

Heart disease and stroke are the leading causes of death and disability among people with Type 2 diabetes. In fact, at least 65 percent of people with diabetes die from some form of heart disease or stroke, according to the American Heart Association. However, a new study by researchers at Wake Forest Baptist Medical Center suggests that the use of cholesterol-lowering statins may help prolong the lives of people with diabetic cardiovascular disease.

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Inherited ‘Memory’ of Environmental Impact on Health May Be Limited

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When a pregnant mother is undernourished, her child is at a greater than average risk of developing obesity and type 2 diabetes, in part due to so-called ‘epigenetic’ effects.

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New Compound Treats Both Blindness and Diabetes in Animal Studies

In a new study led by UC San Francisco (UCSF) scientists, a chemical compound designed to precisely target part of a crucial cellular quality-control network provided significant protection, in rats and mice, against degenerative forms of blindness and diabetes.

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Scripps Florida Scientists Uncover New Compounds that Could Affect Circadian Rhythm

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Scientists from The Scripps Research Institute have discovered a surprising new role for a pair of compounds that have the potential to alter circadian rhythm, the complex physiological process, present in most living things, that responds to a 24-hour cycle of light and dark.

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Drug Shows Promise for Effectively Treating Metabolic Syndrome

Researchers discover that enzyme involved in intracellular signaling plays a crucial role in developing metabolic syndrome, a finding that has a U of U spinoff company developing a drug to potentially treat the condition.

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Two-Drug Combo Shows Promise for Diabetes Research

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The results of The Sanford Project’s first clinical trial are published in the July edition of The Lancet Diabetes & Endocrinology, revealing the outcome of a two-year study exploring the benefits of two drugs in treating type 1 diabetes.

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