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‘Feeding and Fasting’ Hormone Adropin Can Improve Insulin Action

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A SLU researcher has found that adropin, a hormone that regulates whether the body burns fat or sugar during feeding and fasting cycles, can improve insulin action in obese, diabetic mice, suggesting that it may work as a therapy for type 2 diabetes.

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Probiotic Helps Treat Diabetes in Rats, Could Lead to Human Remedy

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In the study, published Jan. 27 in the journal Diabetes, the researchers engineered a strain of lactobacillus, a human probiotic common in the gut, to secrete a Glucagon-like peptide (GLP-1). They then administered it orally to diabetic rats for 90 days and found the rats receiving the engineered probiotic had up to 30 percent lower high blood glucose, a hallmark of diabetes.

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New Brain Pathway Offers Hope for Treating Hypogylcemia

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A novel pathway buried deep within a region of the brain produces a brain hormone that acts as a crucial sensor of blood glucose levels. Understanding how the hormone orchestrates the body's response to low blood sugar offers hope for treating hypoglycemia.

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Light Replaces the Needle

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Empa and the University Hospital Zurich have joined forces to develop a sensor that gages the blood sugar through skin contact. And best of all: No blood samples are necessary, not even to calibrate the sensor. “Glucolight” is initially to be used in premature babies to avoid hypoglycemia and subsequent brain damage.

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SLU Researcher Prevents Type I Diabetes in Lab

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A new approach developed by Saint Louis University researcher Thomas Burris, Ph.D., stops the destruction of beta cells and preserves insulin production.

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Safe and Effective Approaches for Weight Loss in New Year

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Researchers Uncover More Clues to How Drug Reverses Obesity, Diabetes, Fatty Liver Disease

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Researchers at the University of Michigan have identified how a promising drug in clinical trials for the treatment of obesity and related metabolic disorders improves the metabolism of sugar by generating a new signal between fat cells and the liver.

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TSRI Scientists Illuminate Mysterious Molecular Mechanism Powering Cells in Most Forms of Life

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A team led by structural biologists at The Scripps Research Institute has taken a big step toward understanding the intricate molecular mechanism of a metabolic enzyme— nicotinamide nucleotide transhydrogenase—produced in most forms of life on Earth.

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Hacking Fat Cells’ Metabolism Does Not Affect Insulin Resistance

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In the race to find a safe and effective weight loss drug, much attention has focused on the chemical processes that store and use energy. But a new mouse study from Johns Hopkins suggests that tweaking these processes, even in a targeted way that affects only fat cells, may not yield a silver-bullet obesity cure.

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Researcher Identify New Genetic And Epigenetic Contributors To Diabetes

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An analysis of the genomes and epigenomes of lean and obese mice and humans has turned up a wealth of clues about how genes and the environment conspire to trigger diabetes, Johns Hopkins researchers say. Their findings reveal that obesity-induced changes to the epigenome — reversible chemical “tags” on DNA — are surprisingly similar in mice and humans, and might provide a new route to prevention and treatment of the disease, which affects hundreds of millions worldwide.