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Scientists Establish that Drug Candidates Can Block Pathway Associated with Cell Death in Parkinson’s Disease

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In a pair of related studies, scientists from the Florida campus of The Scripps Research Institute have shown their drug candidates can target biological pathways involved in the destruction of brain cells in Parkinson's disease.

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EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 28-Jan-2015 1:00 PM EST

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New Laser-Patterning Technique Turns Metals Into Supermaterials

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By zapping ordinary metals with femtosecond laser pulses researchers from the University of Rochester in New York have created extraordinary new surfaces that efficiently absorb light, repel water and clean themselves. The multifunctional materials could find use in durable, low maintenance solar collectors and sensors.

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Century-Old Drug Reverses Autism-Like Symptoms in Fragile X Mouse Model

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Researchers at UC San Diego School of Medicine previously reported that a drug used for almost a century to treat trypanosomiasis, or sleeping sickness, reversed environmental autism-like symptoms in mice. Now, a new study published in this week’s online issue of Molecular Autism, suggests that a genetic form of autism-like symptoms in mice are also corrected with the drug, even when treatment was started in young adult mice.

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New Research Unlocks How Melanoma Can Resist Newly Approved Drug Combo Therapy

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In a new study researchers at the UCLA Jonsson Comprehensive Cancer Center have uncovered how melanoma becomes resistant to a promising new drug combo therapy utilizing BRAF+MEK inhibitors in patients after an initial period of tumor shrinkage.

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Chemical Dial Controls Attraction Between Water-Repelling Molecules

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A group of University of Wisconsin–Madison researchers has provided new insights on hydrophobic interactions within complex systems. In a study published today in the journal Nature, the researchers show how the nearby presence of polar (water-attracted, or hydrophilic) substances can change the way the nonpolar hydrophobic groups want to stick to each other.

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Cone Snail Venom Holds Promise for Medical Treatments for Cancer and Addiction

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While considered a delicacy in some parts of the world, snails have found a more intriguing use to scientists and the medical profession offering a plethora of research possibilities.

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Possible Treatments Identified for Highly Contagious Stomach Virus

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Antibiotics aren’t supposed to be effective against viruses. But new evidence in mice suggests antibiotics may help fight norovirus, a highly contagious gastrointestinal virus, report scientists at Washington University School of Medicine in St. Louis.

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Water, Water, Everywhere — Controlling the Properties of Nanomaterials

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Properties of water molecules on the surface of metal oxides can be used to better control these minerals and use them to make products such as more efficient semiconductors for organic light emitting diodes and solar cells, safer vehicle glass in fog and frost, and more environmentally friendly chemical sensors for industrial applications.

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“Seeing” Hydrogen Atoms to Unveil Enzyme Catalysis

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A multi-institutional research team led by Chris Dealwis from Case Western Reserve University has used the new IMAGINE instrument at Oak Ridge National Laboratory’s High Flux Isotope Reactor to map an enzyme that could play an important role in anti-cancer drug development.