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Peer Reviewed Publication Confirms the Absence of Rhabdovirus in Cell Line Used for Manufacturing of Flublok®

/PRNewswire/ -- Protein Sciences Corporation is pleased to announce the publication of its manuscript entitled "Complete Study Demonstrating the Absence of Rhabdovirus in a Distinct Spodoptera frugiperda (Sf9) Cell Line" in the peer-reviewed journal PLOS ONE, Volume 12 issue 4. The publication follows extensive testing of the parent cells from which Protein Sciences' proprietary expresSF+® (SF+) cell line is derived. The study confirms that a contaminating rhabdovirus previously reported in a related cell line is not present in SF+ cells. These results demonstrate that not all cell lines are equal even if they are derived from the same parent cell line and highlight the high quality of the SF+ cell lineage.

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brown recluse

Children at Greater Risk for Complications From Brown Recluse Spider Bites

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Medical complications of brown recluse spider bites are uncommon but they can be severe, particularly in children, researchers at Vanderbilt University Medical Center (VUMC) reported today.

Medicine

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genes, Chromosome, Chromosome 19, Barbara R. Migeon, Barbara Migeon

For Keeping X Chromosomes Active, Chromosome 19 Marks the Spot

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After nearly 40 years of searching, Johns Hopkins researchers report they have identified a part of the human genome that appears to block an RNA responsible for keeping only a single X chromosome active when new female embryos are formed, effectively allowing for the generally lethal activation of more than one X chromosome during development.

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conscious sedation, General Anesthesia, transcatheter aortic valve replacement, TAVR, Aortic Stenosis, heart valve replacement, Heart Surgery, Minimally Invasive Surgery

Conscious Sedation Is a Safe Alternative to General Anesthesia for Heart Valve Procedure

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UCLA scientists have found that conscious sedation — a type of anesthesia in which patients remain awake but are sleepy and pain-free — is a safe and viable option to general anesthesia for people undergoing a minimally invasive heart procedure called transcatheter aortic valve replacement.

Medicine

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HIV, Vaccine Design, Volatility, Diffusion, stock price prediction

Financial Math May Help Build a Better HIV Vaccine

Using computational tools inspired by financial math models developed to predict changes in stock prices, University of Iowa researchers were able to accurately predict how different properties of the HIV surface protein (Env) evolved in the population of Iowa over the course of 30 years. The ability to predict such changes by testing a small number of patients could potentially allow tailoring of vaccines to the specific forms of HIV present in different populations worldwide.

Science

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Fungi, Fungal, wood, Copper

Control Pest Fungi in an Environmentally Friendly Way

The St. Gallen-based Empa biotech spin-off, MycoSolutions AG, has developed a new fungal product that improves the soil and controls pest fungi in an environmentally friendly way. Wooden poles remain in use much longer, leading to cost savings of millions for operators. A "Proof-of-Concept" is now available for the integrated wood preservation method.

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Life

Social and Behavioral Sciences

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Male Jumping Spiders Court Whomever, Whenever; Females Decide Who Lives, Dies

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Male jumping spiders will try to mate with any female, but that lack of discretion could cost them their lives, says a University of Florida Institute of Food and Agricultural Sciences researcher.

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Cancer, Melanoma, Melanoma and Skin Cancer Awareness Month, Skin Cancer, Cellular Biology, Microbiology, Biology, Cancer Research

Researchers Document How Melanoma Tumors Form

University of Iowa researchers have documented in continuous, real time how melanoma cells form tumors. The team report the process is similar to that of breast cancer cells and have successfully screened for two antibodies that stopped tumor formation in both cancers. Results published in the journal PLOS One.

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UTI, Urinary Tract Infection , recurrent UTI, Gardnerella vaginalis

Vaginal Bacteria Can Trigger Recurrent UTIs, Study Shows

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Vaginal bacteria can trigger recurrent UTIs, according to a study in mice. The findings help explain why sex is associated with UTIs. When it gets in the bladder, the vaginal bacterium Gardnerella vaginalis triggers dormant E. coli from a prior infection to re-start multiplying, causing another UTI.

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Tackling Resilience: Finding Order in Chaos to Help Buffer Against Climate Change

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A new paper by the University of Washington and NOAA's Northwest Fisheries Science Center aims to provide clarity among scientists, resource managers and planners on what ecological resilience means and how it can be achieved.







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