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Medicine

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Cancer, National Cancer Institute, Case Western Reserve School of Medicine, Grant, Minorites In Medicine, Nathan A. Berger, Case Comprehensive Cancer Center, Cleveland Metropolitan School District, Cleveland, Scientific Enrichment and Opportunity Program, Young Scientist Foundation, Cancer Research, High School, Middle School, Undergraduate, Education

Youth Enjoy Science (YES) Grant Brings Diversity to Cancer Research

Case Western Reserve University School of Medicine, in partnership with the Case Comprehensive Cancer Center, was awarded a five-year grant, totaling $2.5 million to engage underrepresented minorities in Cleveland-area schools in cancer research.

Medicine

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Victor Velculescu, Cancer, fallopian tube

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 23-Oct-2017 5:00 AM EDT

Science

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nematic, active nematic, toroid, toroidal droplets, Microtubules

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 23-Oct-2017 11:00 AM EDT

Science

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Blindness, Myocilin, Glaucoma, glaucoma research, hereditary glaucoma, olfactomedin, Propeller, Protein Misfolding, Protein Misfolding Disease, Trabecular Meshwork, Trabecular, Prion, Amyloid Fibrils, Amyloid, Clogging, y-shape, tripartite, Coiled Coil, dimer, tetramer

‘Y’ a Protein Unicorn Might Matter in Blindness

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A protein shaped like a "Y" makes scientists do a double-take and may change the way they think about a protein sometimes implicated in glaucoma. The Y is a centerpiece in myocilin, binding four other components nicknamed propellers together like balloons on strings.

Medicine

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alzheimer disease, Biomarker, Amyloid, Seniors, Neurology, Brain

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 23-Oct-2017 11:00 AM EDT

Medicine

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Prostate Cancer, Beta Blockers, Nervous System

Study Shows How Nerves Drive Prostate Cancer

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In a study in today’s issue of Science, researchers at Albert Einstein College of Medicine, part of Montefiore Medicine, report that certain nerves sustain prostate cancer growth by triggering a switch that causes tumor vessels to proliferate. Their earlier research—which first implicated nerves in fueling prostate cancer—has prompted Montefiore-Einstein to conduct a pilot study testing whether beta blockers (commonly used for treating hypertension) can kill cancer cells in tumors of men diagnosed with prostate cancer.

Medicine

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Genetics, genes, TMEM106B, Frontotemporal Lobar Degeneration, Ftld, ALS, Alzheimer's Disease, Parkinson's Disease, Neurology, Neurons, Neurodegeneration

Penn Researchers Drill Down into Gene Behind Frontotemporal Lobar Degeneration

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A new study published online this week in the American Journal of Human Genetics from Penn researchers uncovers the mechanisms of the genetic mutations, or variants, associated with the TMEM106B gene.

Medicine

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brain training, Brain Tasks, Hearing, Hearing Aid

Brain Training Can Improve Our Understanding of Speech in Noisy Places

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For many people with hearing challenges, trying to follow a conversation in a crowded restaurant or other noisy venue is a major struggle, even with hearing aids. Now, Mass. Eye and Ear researchers reporting in Current Biology on October 19th have some good news: time spent playing a specially designed, brain-training audiogame could help.

Medicine

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HIV-1, GP41, AIDS, Envelope Protein, Structural Biology, NMR, Retrovirus

Last unknown structure of HIV-1 solved, another step in efforts to disarm the AIDS virus

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Researchers have solved the last unknown protein structure of HIV-1, the retrovirus that can cause AIDS. This will further explain how the virus infects human cells and how progeny viruses are assembled and released from infected cells.

Medicine

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ferroptosis, Hülya Bayɪr, Valerian Kagan, Sally Wenzel, Cell Death, PEBP1, Asthma, Kidney Injury, Brain Trauma, 15LO

Tracing Cell Death Pathway Points to Drug Targets for Brain Damage, Kidney Injury, Asthma

University of Pittsburgh scientists are unlocking the complexities of a recently discovered cell death process that plays a key role in health and disease, and new findings link their discovery to asthma, kidney injury and brain trauma. The results, reported today in the journal Cell, are the early steps toward drug development that could transform emergency and critical care treatment.







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