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A reporter's PressPass is required to access this story until the embargo expires on 2-Feb-2015 3:00 PM EST

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A reporter's PressPass is required to access this story until the embargo expires on 2-Feb-2015 11:00 AM EST

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New Clues About a Brain Protein with High Affinity for Valium

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Valium, one of the best known antianxiety drugs, produces its calming effects by binding with a particular protein in the brain. But the drug has an almost equally strong affinity for a completely different protein. New studies revealing atomic level details of this secondary interaction might offer clues about Valium's side effects and point the way to more effective drugs.

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Analysis of Key Breast Cancer Genes Reveals Distinct Profiles for African-American and European-American Women

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In a large study using data from the Women's Circle of Health Study, epidemiologists have determined that gene variations associated with breast cancer risk diverged significantly between African-American and women of European descent.

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Grant Enables Rutgers Cancer Institute of New Jersey Investigators to Explore Melanoma Metastasis

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The mechanism by which small cellular vesicles promote melanoma metastasis (spread of disease), will be further explored by investigators at Rutgers Cancer Institute of New Jersey and the Rutgers Ernest Mario School of Pharmacy. The goal is to search for a possible correlation between exosome production and biologic response in patients with melanoma.

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Child Maltreatment Not a Clear Path to Adult Crime

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Research has long made a connection between childhood abuse and neglect and crime in adulthood. But a University of Washington study found that when other life factors are considered, that link all but disappears.

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Earlier Menopause Linked to Everyday Chemical Exposures

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Women whose bodies have high levels of chemicals found in plastics, personal-care products, common household items and the environment experience menopause two to four years earlier than women with lower levels of these chemicals, according to a new study at Washington University School of Medicine in St. Louis. The findings are reported online Jan. 28 in the journal PLOS ONE.

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Dartmouth Investigators Conduct Systematic Testing of Deimmunized Biotherapeutic Agents

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By establishing protein design algorithms that simultaneously optimize drug candidates for both decreased immunogenic epitope content and high level stability and activity, researchers have established a novel testing platform.

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Innovative Program to Add New Segment to STEM Education Pipeline at UNM

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Angela Wandinger-Ness, PhD, will use a NCI-CURE grant to include underrepresented minority high school students in the UNM STEM education pipeline.