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Glaucoma Drug Helps Women with Blinding Disorder Linked to Obesity

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An inexpensive glaucoma drug, when added to a weight loss plan, can improve vision for women with idiopathic intracranial hypertension (IIH), according to a study funded by NEI. This disorder mostly affects young, overweight women. Vision loss and headaches are common symptoms.

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Bioinformatics Profiling Identifies a New Mammalian Clock Gene

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Over 15 mammalian clock proteins have been identified, but researchers surmise there are more. Could big-data approaches help find them? To accelerate clock-gene discovery, the investigators used a computer-assisted approach to identify and rank candidate clock components, which they liken to online Netflix-like profiling of movie suggestions for customers. This approach found a new core clock gene, which the team named CHRONO.

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A reporter's PressPass is required to access this story until the embargo expires on 4/24/2014 12:00 PM EDT

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Blue-Footed Boobies’ Survival Threatened

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Blue-footed boobies are on the decline in the Galápagos because of a low sardine diet.

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The Future of High-Speed Rail in the U.S. And Beyond

Wayne State University, in partnership with the University of Michigan and Drexel University, has launched a two-and-a-half-year study of the imagination — or l'imaginaire — of high-speed rail (HSR) in America. The study is part of a larger comparative international study piloted by Dr. Max Bergman at the University of Basel and led by French, American, South African, Indian and Chinese research teams that is exploring the role of the “imaginaries” in choices relative to train and rail infrastructures. In other words, the study will examine what motivates decision makers (both leaders and users) in regard to championing or using trains both in and of themselves and within the context of the future of transportation as a whole.

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Sleeping Away Infection: Penn Researchers Find Link between Sleep and Immune Function in Fruitflies

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When we get sick it feels natural to try to hasten our recovery by getting some extra shuteye. Researchers found that this response has a definite purpose, in fruitflies: enhancing immune system response and recovery to infection.

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Safer Alternatives to Nonsteroidal Antinflamatory Pain Killers

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Building on previous work that showed that deleting an enzyme in the COX-2 pathway in a mouse model of heart disease slowed the development of atherosclerosis, researchers have now extended this observation by clarifying that the consequence of deleting the enzyme mPEGS-1 differs, depending on the cell type in which it is taken away. They are now working on ways to deliver inhibitors of mPGES-1 selectively to the macrophages.

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