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Medicine

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UTI, Urinary Tract Infection , E. Coli, UPEC

Researchers Identify Protein Critical in Causing Chronic UTIs

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Researchers have identified a way to prevent chronic urinary tract infections (UTIs). Vaccinating mice against a key protein that bacteria use to latch onto the bladder and cause UTIs reduces severe disease, according to researchers at Washington University School of Medicine in St. Louis.

Medicine

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National Science Foundation, Wayne State University, Urban Health, urban life, Health Informatics

Wayne State Professor Receives $200,000 NSF Grant to Develop Data-Driven Health Informatics System to Address Urban Health Challenges

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Wayne State University recently received notice of a nearly $200,000 grant from the National Science Foundation that aims to address the many health challenges faced in urban communities due to the increasing complexity of urban life, declining urban services, and growing health and economic disparities. The team science project will focus on childhood obesity disparities, one example of the negative consequences of such challenges.

Medicine

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drug deliver, Tumor, Cancer, magnetic bacteria

Swarms of Magnetic Bacteria Could Be Used to Deliver Drugs to Tumors

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Researchers have recently shown that magnetic bacteria are a promising vehicle for more efficiently delivering tumor-fighting drugs.

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Science

Life

Business

Law and Public Policy

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Presidential Debate: Expert Panel Gives Scientific Analysis of Candidates' Performances

Four expert panelists each day will present their analyses and answer your questions live and face-to-face. This event will be virtual. You can attend with any device -- PC, Mac, iPad, iPhone or Android device (with a webcam) – anywhere with good bandwidth. To participate (ask questions) in the meeting, you must be on video, just as a normal news conference. Register below for guaranteed seating; there is limited seating in the virtual room. Eight experts (four at each event) will present their analyses. The diverse expert team (7 universities and an institute) will analyze both candidates during the debates for their gestures, facial expressions (including smiles--number, type, appropriateness, etc.), posture, language, including sentiment, tone, inflammatory language, repetition, vocabulary, sentence structure, metaphors, framing, themes, suggestions, subtlety, nuance, honesty (deceit/lies—explicit and implicit), transparency, gender issues, and more...

Medicine

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Nicotine, Smoking, Texas A&M Health Science Center

Can Nicotine Protect The Aging Brain?

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Everyone knows that tobacco products are bad for your health. However, according to research at Texas A&M, it turns out the nicotine itself—when given independently from tobacco—could help protect the brain as it ages, and even ward off Parkinson’s or Alzheimer’s disease.

Medicine

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Crohn Disease, Fungus, Bacteria, Microbiology

Case Western Reserve-Led International Team Identifies Fungus in Humans for First Time as Key Factor in Crohn’s Disease

A Case Western Reserve University School of Medicine-led team of international researchers has for the first time identified a fungus as a key factor in the development of Crohn’s disease.

Medicine

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Genetics, DNA, Genetic Variant

Scientists Discover Distant DNA Working Together to Affect Disease Risk

New research out of Case Western Reserve University School of Medicine suggests the 3-D structure DNA forms as it crams into cells may provide an additional layer of gene control.

Science

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Catalysis, Chemistry, heterogeneous catalysis, Carbon dioxide conversion, Spectroscopy, nanotechnnology

Making Catalysts Smarter

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The industrial catalysts of the future won’t just speed up reactions, they’ll control how chemical processes work and determine how much of a particular product is made.

Medicine

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Abdominal Aortic Aneurysm, Calorie Restriction, low calorie diet, Sirt1, Epigenetics, Mmp 2

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 26-Sep-2016 9:00 AM EDT

Medicine

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Allergies, Rush Desensitization, Antigens, Mast Cells

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 26-Sep-2016 4:00 PM EDT

Science

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Whitehead Institute, Rudolf Jaenisch, Methylation, Inherited, Imprinted, Dynamic, Aging Brain, Neural Cells

Inherited Parental Methylation Shifts Over Time, May Have Functional Effects in the Brain and Other Tissues

Inherited methylation—a form of epigenetic regulation passed down from parents to offspring—is far more dynamic than previously thought and may contribute to changes in the brain and other tissues over time. This finding by Whitehead Institute scientists challenges current understandings of gene regulation via methylation, from development through adulthood.

Science

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Crohn's Diease, Ulcerative Colitis, Inflammatory Bowel Disease, IBD, Colorectal Cancer, Colon Cancer, Paneth Cells

New Therapeutic Target for Crohn’s Disease

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Research from the Sanford Burnham Prebys Medical Discovery Institute (SBP) identifies a promising new target for future drugs to treat inflammatory bowel disease (IBD). The study, published today in Cell Reports, also indicates that another protein, protein kinase C (PKC) λ/ι, may serve as a biomarker of IBD severity.

Medicine

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Fragile X Syndrome, Autism, hyperexcitability disorders

New Explanation Offered for Symptoms of Fragile X Syndrome

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A new explanation for some of the symptoms of fragile X syndrome, the most common inherited cause of intellectual disability, has been proposed by researchers at Washington University School of Medicine in St. Louis. Their explanation suggests new targets for treatment.

Medicine

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pediatric neurology, Childhood Epilepsy, severe epileptic encephalopathy, Genetics, Precision Medicine, Pediatrics

Gene Discovery in Severe Epilepsy May Offer Clues to Unique Personalized Therapies

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An international team of researchers who discovered a new gene disorder that causes severe childhood epilepsy leveraged that finding to reduce seizures in two children. The collaborators’ case report reflects the potential of precision medicine--applying basic science knowledge to individualize treatment to a patient’s unique genetic profile

Science

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Anthrax, Toxin, Structural Biology, Lethal Factor

EMBARGOED

A reporter's PressPass is required to access this story until the embargo expires on 26-Sep-2016 9:00 AM EDT

Medicine

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Eye Disease, Photoreceptors, Drosophila, Blindness, blindness research, autosomal recessive retinitis pigmentosa, glacoma, age-related macular degeneration, Drosophila Melanogaster, Diabetic Retinopathy, Cataracts, Basic Research, Science, Biology

NIH Grants IU $1.9 Million to Advance Blindness Prevention Through Basic Research on Photoreceptors

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A $1.9 million grant to Indiana University from the National Institutes of Health's National Eye Institute will advance basic research on the eye with applications to blindness caused by genetic disorders and aging.

Medicine

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HIV and AIDS, Hiv Treatment

Targeting Dormant HIV

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Discovery of a novel, advanced technique to identify the rare cells where human immunodeficiency virus (HIV) hides in patients taking antiretroviral therapy (ART). This is an important step forward in the search for a HIV/AIDS cure.

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Specialized Test Detects Bacterial Infections in Youngest Infants with Fever

Physicians from Children’s Hospital of Michigan, Wayne State University, UC Davis Medical Center and Nationwide Children's Hospital, in collaboration with 19 other pediatric emergency departments around the country, have established a “proof of principle” for measuring patterns of ribonucleic acid (RNA) expression in the bloodstream that can enable clinicians to distinguish bacterial infections from other causes of fever in infants up to two months old.

Science

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National Institute Of Environmental Health Sciences, Niehs, mercury exposure, Aerobic Exercise, Cognitive Function, Methylmercury, Harvard T.H. Chan School of Public Health

Brain Benefits of Aerobic Exercise Lost to Mercury Exposure

Cognitive function improves with aerobic exercise, but not for people exposed to high levels of mercury before birth, according to research funded by the National Institute of Environmental Health Sciences (NIEHS), part of the National Institutes of Health. Adults with high prenatal exposure to methylmercury, which mainly comes from maternal consumption of fish with high mercury levels, did not experience the faster cognitive processing and better short term memory benefits of exercise that were seen in those with low prenatal methylmercury exposures.

Medicine

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Cancer, Breast Cancer, Lymphedema, Surgery, Lymphadenectomy, Retinoic Acid, Retinol, cancer treatment side effects

Retinoic Acid May Significantly Prevent Lymphedema Development, Experimental Model Suggests

Using newly updated mouse models, USC researchers demonstrated the impactful preventive properties of 9-cis retinoic acid against lymphedema. Currently, there is no cure for lymphedema, a swelling of the extremities that most commonly occurs after treatment for cancer.







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