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Mayo Researchers Reveal Pathway that Contributes to Alzheimer’s Disease

Researchers at Jacksonville’s campus of Mayo Clinic have discovered a defect in a key cell-signaling pathway they say contributes to both overproduction of toxic protein in the brains of Alzheimer’s disease patients as well as loss of communication between neurons — both significant contributors to this type of dementia.

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MS Drug Candidate Shows New Promise

Positive new data have been released on a drug candidate, RPC1063, for relapsing multiple sclerosis that was first discovered and synthesized at The Scripps Research Institute (TSRI).

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Mouse Model Sheds Light Mitochondria's Role in Neurodegenerative Diseases

A new study by researchers at the University of Utah School of Medicine sheds light on a longstanding question about the role of mitochondria in debilitating and fatal motor neuron diseases and resulted in a new mouse model to study such illnesses.

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Scientists Discover “Dimmer Switch” for Mood Disorders

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Researchers at University of California, San Diego School of Medicine have identified a control mechanism for an area of the brain that processes sensory and emotive information that humans experience as “disappointment.”

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Down Syndrome Helps Researchers Understand Alzheimer’s Disease

The link between a protein typically associated with Alzheimer’s disease and its impact on memory and cognition may not be as clear as once thought, according to a new study from the University of Wisconsin-Madison’s Waisman Center. The researchers looked at the role of the brain protein amyloid-β in adults living with Down syndrome, a genetic condition that leaves people more susceptible to developing Alzheimer’s.

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JHU Researchers Make New Discovery about 3D Shape Processing in the Brain

While previous studies of the brain suggest that processing of objects and places occurs in very different locations, a research team has now found that they are closely related.

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A reporter's PressPass is required to access this story until the embargo expires on 24-Sep-2014 4:00 PM EDT

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UNC Researchers Link Gene to Increased Dendritic Spines – a Signpost of Autism

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UNC scientists discover that knocking out the gene NrCAM increases the number of dendritic spines on excitatory pyramidal neurons. Other studies have confirmed that the overabundance of dendritic spines allows for too many synaptic connections – a phenomenon strongly linked to autism.

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A reporter's PressPass is required to access this story until the embargo expires on 23-Sep-2014 4:00 AM EDT

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Novel Mechanism Involved in Memory Discovered by UAB Researchers

Researchers at UAB report in Nature the discovery of a novel mechanism in the brain involved in the formation of memory and learning. The discovery could have therapeutic ramifications for conditions including dementia, age-related memory loss or even post-traumatic stress disorder.

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