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Medicine

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Diabetes, insulin spray, Insulin, Cognitive Decline, Mild Cognitive Impairment, Memory, Aging, Alzheimer's Disease

Sniffing Out a New Strategy Against Alzheimer’s Disease

Neurologists at the Rush Alzheimer’s Disease Center are conducting an 18-month clinical trial testing a type of insulin delivered in a nasal spray – which is used to treat diabetes in some patients – in the Study of Nasal Insulin to Fight Forgetfulness (SNIFF).

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Which Drugs Effectively Treat Diabetic Nerve Pain?

A federal health agency has found certain antidepressants and anti-seizure drugs are among medications that effectively treat diabetic nerve pain. The research is being published simultaneously in the March 24, 2017, online issue of Neurology®, the medical journal of the American Academy of Neurology (AAN) and in a more comprehensive report by the Agency for Healthcare Research and Quality (AHRQ).

Medicine

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Neurobiology, Vascular Biology, Stroke, Brain, Cerebrovascular

Electrical “Switch” in Brain’s Capillary Network Monitors Activity and Controls Blood Flow

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New research has uncovered that capillaries have the capacity to both sense brain activity and generate an electrical vasodilatory signal to evoke blood flow and direct nutrients to neurons.

Science

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Chronobiology, Astrocytes, master clock

Clock Stars: Astrocytes Keep Time for Brain, Behavior

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Star-shaped cells called astrocytes, long considered boring, “support cells,” are finally coming into their own. To everyone’s surprise they even play an important role in the body’s master clock, which schedules everything from the release of hormones to the onset of sleepiness.

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Amyotrophic Lateral Sclerosis (Als), ALS, Genetics, Jumping Genes, Neurodegeneration

Research Suggests a Possible Role for a Storm of “Jumping Genes” in ALS

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By inserting an amyotrophic lateral sclerosis (ALS)-linked human gene called TDP-43 into fruit flies, researchers at Stony Brook University and Cold Spring Harbor Laboratory discovered a potential role for ‘transposons’ in the disease.

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Childhood Brain Tumor, Body Fat

Survivors of Childhood Brain Tumours Have Increased Body Fat

These findings suggest that one of the most important risk factors for heart disease and Type 2 diabetes, which is excess total and central fat in the body, is present relatively early in survivors of childhood brain tumors. This may program their future risk of these diseases and impact their outcomes. This indicates that these children need further monitoring for the factors that increase their risk of cardiovascular disease and Type 2 diabetes, and that targeted therapies and prevention strategies are needed to deal with the early risk factors to improve survival and the quality of life of survivors.

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Drug Trial for Solid Cancer Tumors, Lynch Syndrome Awareness, Side Effects for Prostate Cancer Treatments, and More in the Cancer News Source

Click here to go directly to the Cancer News Source

Medicine

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nerve synapse, Neurons

Scientists Get Closer Look at Living Nerve Synapses

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The brain hosts an extraordinarily complex network of interconnected nerve cells that are constantly exchanging electrical and chemical signals at speeds difficult to comprehend. Now, scientists at Washington University School of Medicine in St. Louis report they have been able to achieve — with a custom-built microscope — the closest view yet of living nerve synapses.

Medicine

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Axon Degeneration, Parkinson’s disease , Nerve Cells

Surprising Culprit in Nerve Cell Damage Identified

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In new research, scientists at Washington University School of Medicine in St. Louis have implicated a specific molecule in the self-destruction of axons, the wiring of the nervous system. Understanding just how that damage occurs may help researchers find a way to halt it.

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Biology, Regenerative Medicine, regenerative biology

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