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Researchers Discover Genetic Links to Size of Brain Structures

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Five genetic variants that influence the size of structures within the human brain have been discovered by an international team that included a Georgia State University researcher.

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New Brain Pathway Offers Hope for Treating Hypogylcemia

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A novel pathway buried deep within a region of the brain produces a brain hormone that acts as a crucial sensor of blood glucose levels. Understanding how the hormone orchestrates the body's response to low blood sugar offers hope for treating hypoglycemia.

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Research Suggests Anti-Inflammatory Protein May Trigger Plaque in Alzheimer’s Disease

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Inflammation has long been studied in Alzheimer’s, but in a counterintuitive finding reported in a new paper, University of Florida researchers have uncovered the mechanism by which anti-inflammatory processes may trigger the disease.

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Blame It on Your Brain: Salt and Hypertension

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An international research team led by scientists at McGill University has found that excessive salt intake “reprograms” the brain, interfering with a natural safety mechanism that normally prevents the body’s arterial blood pressure from rising.

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Rare Neurological Disease Shines Light on Health of Essential Nerve Cells

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Pelizaeus Merzbacher disease, or PMD, is a devastating neurological condition that, in its most severe form, kills infants weeks after birth. Thirty years ago, UW-Madison neuroscientist Ian Duncan noticed a genetic mutation in dogs that was practically identical to the disease in humans. Now, in the online edition of the journal Neurobiology of Disease, Duncan has laid out the results of his marathon pursuit of PMD.

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Study Detailing Axonal Death Pathway May Provide Drug Targets for Neurodegenerative Diseases

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Axons connect neurons with each other to form the neural networks that underpin the vital functions of perception, motility, cognition, and memory. In many neurodegenerative disorders, from traumatic injury or toxic damage to diseases such as Alzheimer’s or Parkinson’s disease, axonal degeneration represents an essential pathological feature.