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Medicine

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Case Western Reserve School of Medicine, NIH, Creutzfeldt Jacob Disease, CJD, Prions, prion transmission, National Prion Disease Pathology Surveillance Center , Wenquan Zou, CJD diagnosis, prion infections, Brain Health, Byron Caughey, Surgeries, Brain Surgery, non-neurosurgeries, Neurosurgeries, University Hospitals Cleveland Medical Center

Researchers Find Infectious Prions in Creutzfeldt-Jakob Disease Patient Skin

In a Science Translational Medicine study published today, Case Western Reserve University School of Medicine researchers found that CJD patients also harbor infectious prions in their skin, albeit at lower levels. In the study, the researchers collected skin samples from 38 patients with assistance from the National Prion Disease Pathology Surveillance Center at Case Western Reserve School of Medicine and measured their prion levels. Using a highly sensitive in vitro assay developed and conducted by Byron Caughey’s group at the NIH, they detected prion protein aggregates in the skin samples from all of CJD patients. Prion levels were 1,000-100,000 times lower in the skin than in the brain, and only detectable by this extremely sensitive assay. The researchers further demonstrated that such skin prions are infectious, since they are capable of causing disease in humanized mouse models.

Life

Social and Behavioral Sciences

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Dementia Risk, Alzheimer's, Research, Memory, Nueroscience, Higher Education

Alzheimer’s Awareness Month: As Numbers Diagnosed Grow, So Does Promising Research

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Researchers at Fresno State and CSU Fullerton are among those studying better ways to prevent the most common form of dementia.

Medicine

Science

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Alzheimer's, Memory, Aging

To Forget or to Remember? Memory Depends on Subtle Brain Signals, Scientists Find

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Understanding how brains actively erase memories may open new understanding of memory loss and aging, and open the possibility of new treatments for neurodegenerative disease.

Medicine

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Autism, Autism Spectrum Disorder, Brain, Disabilities, Games, Video Games, Kinesiology, Balance

Video Game Improves Balance in Youth with Autism

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Playing a video game that rewards participants for holding various “ninja” poses could help children and youth with autism spectrum disorder (ASD) improve their balance, according to a recent study in the Journal of Autism and Developmental Disorders led by researchers at the University of Wisconsin-Madison.

Life

Education

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Greg Duncan, Child Development, Research, Brain, Education, Poverty

UCI Wins Federal Grant to Explore Link Between Family Income, Early Brain Development

Based on a growing body of small-scale studies documenting that brain development in children from low-income households differs from brain development in children from higher-income households, the Eunice Kennedy Shriver National Institute of Child Health & Human Development has awarded $7.8 million to the University of California, Irvine for a five-year research project.

Medicine

Science

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Pesticides, Aging, Parkinson Disease, Neurodegeneration

Good Cells Gone Bad

A new study from The Scripps Research Institute (TSRI) is the first to show precisely how a process in nerve cells called the S-nitrosylation (SNO) reaction—which can be caused by aging, pesticides and pollution—may contribute to Parkinson’s disease.

Life

Social and Behavioral Sciences

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Communication, Learning, self-development, proactive approach, proactive approach to learning, Goals, achieve goals, Neuroscience

Wichita State University Professor Co-Authors Third Book in Personal Development Series

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Ray Hull, professor of Communication Sciences and Disorders at Wichita State University, understands that the ability to learn is imperative for every person seeking a goal. This is why he included "The Art of Learning and Self-Development" in the personal development series that he co-authors with New York Times best-selling author Jim Stovall.

Medicine

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Depression, Major Depressive Disorder, Bipolar Disorder, EKG, elecgtrocardiogam, Heart Rate Variability, Respiratory Sinus Arrhythmia, RSV

Simple Electrocardiogram Can Determine Whether a Patient Has Major Depression or Bipolar Disorder, Study Finds

A groundbreaking Loyola Medicine study suggests that a simple 15-minute electrocardiogram could help a physician determine whether a patient has major depression or bipolar disorder.

Medicine

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Inflammatory Bowel Disease, IBD, Tumor Necrosis Factor, TNF

Study to Examine How Tumor Necrosis Factor Works to Reduce Intestinal Inflammation

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An investigator at Children’s Hospital Los Angeles, has been awarded $1.5 million by the National Institute of Diabetes and Digestive and Kidney Diseases of the NIH for the study of tumor necrosis factor (TNF) and its role in inflammatory bowel disease (IBD).

Medicine

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Concussion, RNA, Microrna, TBI, Traumatic Brain Injury

Molecules in Spit May Be Able to Diagnose and Predict Length of Concussions

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Diagnosing a concussion can sometimes be a guessing game, but clues taken from small molecules in saliva may be able to help diagnose and predict the duration of concussions in children, according to researchers at Penn State College of Medicine.







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