Credit: Credit: Usman Khan/lab of Scott A. Small, MD, Columbia University Medical Center.
Alzheimer's disease starts in the entorhinal cortex (yellow). Using fMRI in mouse (left) and human (right) brains, the researchers provide evidence that the disease spreads from the entohrinal cortex (yellow) to other cortical regions (red) — the perirhinal cortex and posterior parietal cortex.