Credit: BY HEATHER A. HUNDLEY, GENE YEO AND MICHAEL C. WASHBURN
Messenger RNAs charted, with A's and I's representing specific nucleotides. ADR-1 does not alter editing activity of ADR-2 at all of the hundreds of newly found editing sites, but the ability of ADR-1 to bind to these mRNAs is required for its regulatory activity at the majority of ADR-1 affected editing sites.