The cholinergic neurons of a healthy mouse at 12 months of age (left) compared to those of a mouse with "Alzheimer's disease" at 7 months (right). The diseased neurons are fragmented and show clumps of what may be cellular debris.
Actual and relative dimensions of a human cholinergic neuron. (Top) Total length of the branches if placed end to end; (middle) length of the central “pipeline” connecting the branches to the cell’s hub (soma; bottom).