JAMA - Journal of the American Medical Association
Chicago, IL USA

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Waistlines of U.S. Adults Continue to Increase

The prevalence of abdominal obesity and average waist circumference increased among U.S. adults from 1999 to 2012, according to a study in the September 17 issue of JAMA.
12-Sep-2014 12:00 PM EDT

Combination Therapy for COPD Associated With Better Outcomes

Among older adults with chronic obstructive pulmonary disease (COPD), particularly those with asthma, newly prescribed long-acting beta-agonists (LABAs) and inhaled corticosteroid combination therapy, compared with newly prescribed LABAs alone, was...
12-Sep-2014 12:30 PM EDT

Effect of Magnesium Sulfate During Pregnancy on Very Preterm Infants

Magnesium sulfate given intravenously to pregnant women at risk of very preterm birth was not associated with benefit on neurological, behavioral, growth, or functional outcomes in their children at school age, according to a study in the September...
12-Sep-2014 12:00 PM EDT

Study Compares Effectiveness of Treatments for Blood Clots

In an analysis of the results of nearly 50 randomized trials that examined treatments of venous thromboembolisms (blood clot in a vein), there were no significant differences in clinical and safety outcomes associated with most treatment strategies...
12-Sep-2014 12:00 PM EDT

New Guideline Created for Managing Sickle Cell Disease

An expert panel has created a new evidence-based guideline for managing sickle cell disease (SCD), with a strong recommendation for the use of the drug hydroxyurea and transfusion therapy for many individuals with SCD, although high-quality evidence...
4-Sep-2014 5:00 PM EDT

Long-Term Follow-up Shows Benefit of Statin Therapy for Children With Inherited Cholesterol Disorder

Ten-year follow-up of children who have been taking statin therapy for an inherited cholesterol disorder showed benefit on a measure of atherosclerosis, although levels of low-density lipoprotein suggested that stronger or earlier initiation of...
4-Sep-2014 5:00 PM EDT

Reanalyses of Data From RCTs Can Lead to Different Conclusions

Although only a small number of reanalyses of data from randomized clinical trials (RCTs) have been published, an examination of those that have been conducted finds that about one-third led to changes in findings that implied conclusions different...
4-Sep-2014 5:40 PM EDT

Comparison of Named Diet Programs Finds Little Difference in Weight Loss Outcomes

In an analysis of data from nearly 50 trials including about 7,300 individuals, significant weight loss was observed with any low-carbohydrate or low-fat diet, with weight loss differences between diet programs small, findings that support the...
28-Aug-2014 11:00 PM EDT

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