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A Long-noncoding RNA Regulates Repair of DNA Breaks in Triple-Negative Breast Cancer Cells

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Using a clinically guided genetic screening approach, researchers identified a non-coding RNA that is overexpressed in triple-negative breast cancer cells and regulated by the tumor suppressor p53 and the activated cell surface protein, EGFR. This...
29-Apr-2016 12:05 PM EDT Add to Favorites

Genetic Risk Factors of Disparate Diseases Share Similar Biological Underpinnings

The discovery of shared biological properties among independent variants of DNA sequences offers the opportunity to broaden understanding of the biological basis of disease and identify new therapeutic targets.
28-Apr-2016 3:05 PM EDT Add to Favorites

Cholesterol Levels, Not Statins, Influence Colorectal Cancer Risk, Penn Study Suggests

Long-term use of the cholesterol-lowering drugs known as statins does not appear to decrease a patient’s risk of colorectal cancer, suggests a new, large case-control study from Penn Medicine researchers published this week in PLOS Medicine.
26-Apr-2016 8:05 AM EDT Add to Favorites

Penn Medicine Study Uncovers New Pathways That Control Skin Tanning and Lightening

When skin cells responsible for pigmentation are exposed to estrogen or progesterone, the cells respond by adjusting their melanin production, resulting in either skin darkening or lightening. Although pregnant women often experience alterations in...
21-Apr-2016 4:05 PM EDT Add to Favorites

Penn Study on Fragile X Syndrome Uses Fruitfly’s Point of View to Identify New Treatments

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The hormone insulin – usually associated with diabetes -- is involved in the daily activity patterns and cognitive deficits in the fruitfly model of FXS. Results reveal a metabolic pathway that can be targeted by new and already approved drugs to...
26-Apr-2016 11:05 AM EDT Add to Favorites

Medicare Patients Have Low Adherence to Biologic Drug Therapy for Psoriasis

About half of Medicare patients who start taking biologic therapies for moderate to severe plaque psoriasis stop within a year, according to a study led by researchers from the Perelman School of Medicine at the University of Pennsylvania. Previous...
25-Apr-2016 4:05 PM EDT Add to Favorites

Penn Study Suggests Changes in Skin “Microbiome” During Canine Atopic Dermatitis Could Lead to Antibiotic-Free Therapies for Human and Canine Disease

Atopic dermatitis (AD), a chronic inflammatory skin condition and the most common form of eczema, is estimated to afflict as much as 10 percent of the U.S. population, and is much more common now than it was 50 years ago. Veterinary clinical...
25-Apr-2016 1:05 PM EDT Add to Favorites

Penn Medicine Awarded Fellowship to Train Next Generation of Parkinson’s Specialists

The University of Pennsylvania Parkinson’s Disease and Movement Disorders Center has been chosen to host the 2017-2019 Edmond J. Safra Fellowship in Movement Disorders by The Michael J. Fox Foundation, in collaboration with its longtime supporter...
21-Apr-2016 3:05 PM EDT Add to Favorites

Our Experts on Newswise

Teen Decision-Making Expert Available to Provide Insight Into Choices Being Made by Teenagers During Spring Rites of Passage - Prom, Graduation, Senior Week.

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18-Apr-2016 1:05 PM EDT

Penn Medicine Zika Virus Experts Available for Interviews

2-Feb-2016 11:05 AM EST

Penn Sleep Specialist Available to Discuss How School Schedules Can Impact Sleep

28-Aug-2015 12:05 PM EDT

Dean of Penn’s Perelman School of Medicine: Precision Medicine is “Personalized, Problematic, and Promising”

- The rapidly emerging field of precision medicine is a “disruptive innovation” that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson,...
26-May-2015 4:00 PM EDT

Penn Medicine Experts Offer Suggestions for Nudging Children toward Healthier Food Choices

Strategies aimed at reducing childhood obesity should acknowledge individuals’ rational taste preferences and apply insights from behavioral economics to design choice architecture that increases their likelihood of success, say two...
19-Mar-2015 11:00 AM EDT

Health & Medicine at the 2014 Sochi Olympics: Penn Medicine Experts Available for Comment

Penn Medicine physicians and scientists are available for comment on a variety of topics relating to health and injury issues that Winter Olympic athletes may face. Experts are available for interviews by phone, webcam or satellite uplink from the...
6-Feb-2014 3:00 PM EST

Penn Medicine Surgeons Available to Discuss the Robotic Surgery Dr. Drew Chose to Treat His Prostate Cancer

25-Sep-2013 3:40 PM EDT

Penn Medicine Experts Available for Comment on Latest Research at SLEEP 2013

28-May-2013 11:00 AM EDT

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