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Penn Medicine and LouLou Foundation Create Program of Excellence for Rare Genetic Disorder That Affects Children

The London-based LouLou Foundation and the Orphan Disease Center of the Perelman School of Medicine at the University of Pennsylvania have established a Program of Excellence to develop effective treatments for children with CDKL5, a rare...
5-Feb-2016 8:00 AM EST Add to Favorites

It's All About the Timing: Fetal Expression of Core Clock Gene Determines Lifespan in Mice


Abolishing the 24-hour clock by knocking out a key gene during development accelerates aging and shortens lifespan by two thirds in mice, but this effect is absent if the gene deletion is delayed until after birth
3-Feb-2016 10:05 AM EST Add to Favorites

Penn Study Identifies Enzyme Key to Link Between Age-Related Inflammation and Cancer


For the first time, researchers have shown that an enzyme key to regulating gene expression -- and also an oncogene when mutated -- is critical for the expression of numerous inflammatory compounds that have been implicated in age-related increases...
3-Feb-2016 10:05 AM EST Add to Favorites

"Gene Fusion" Mutation Uses Three-Way Mechanism To Drive Childhood Brain Cancers


A powerful, three-way mechanism by which a mutation drives the growth of childhood brain cancers, was discovered by scientists. The team hopes the discovery will lead to better methods for diagnosing and treating these cancers, which cannot always...
3-Feb-2016 9:05 AM EST Add to Favorites

Viral Gene Editing System Corrects Genetic Liver Disease in Newborn Mice


For the first time, researchers have treated an animal model of a genetic disorder using a viral vector to deliver genome-editing components in which the disease- causing mutation has been corrected. Delivery of the vector to newborn mice improved...
1-Feb-2016 1:05 PM EST Add to Favorites

Transplant Centers Often Reject Potential Donor Livers for Sickest Patients in Need, Says New Penn Medicine Research


As patients in desperate need of a liver transplant lay waiting, many livers that might give them a new life go unused by centers across the nation, according to new research from the Perelman School of Medicine at the University of Pennsylvania.
27-Jan-2016 2:05 PM EST Add to Favorites

Two Gatekeepers for One Gate: Solving the Mystery of Cell Powerhouse’s Balance of Calcium


A decades-long mystery of how the cell’s powerhouse, and its energy currency of calcium ion flow, is maintained under different physiological conditions has been solved. The team identified a novel regulatory mechanism that governs levels of...
25-Jan-2016 2:05 PM EST Add to Favorites

Penn-Engineered Neural Networks Show Hope for Axonal Repair in the Brain, with Minimal Disruption to Brain Tissue


Lab-grown neural networks have the ability to replace lost axonal tracks in the brains of patients with severe head injuries, strokes or neurodegenerative diseases and can be safely delivered with minimal disruption to brain tissue, according to new...
20-Jan-2016 2:05 PM EST Add to Favorites

Our Experts on Newswise

Penn Medicine Zika Virus Experts Available for Interviews

2-Feb-2016 11:05 AM EST

Penn Sleep Specialist Available to Discuss How School Schedules Can Impact Sleep

28-Aug-2015 12:05 PM EDT

Dean of Penn’s Perelman School of Medicine: Precision Medicine is “Personalized, Problematic, and Promising”

- The rapidly emerging field of precision medicine is a “disruptive innovation” that offers the possibility of remarkably fine-tuned remedies to improve patient health while minimizing the risk of harmful side effects, says J. Larry Jameson,...
26-May-2015 4:00 PM EDT

Penn Medicine Experts Offer Suggestions for Nudging Children toward Healthier Food Choices

Strategies aimed at reducing childhood obesity should acknowledge individuals’ rational taste preferences and apply insights from behavioral economics to design choice architecture that increases their likelihood of success, say two...
19-Mar-2015 11:00 AM EDT

Health & Medicine at the 2014 Sochi Olympics: Penn Medicine Experts Available for Comment

Penn Medicine physicians and scientists are available for comment on a variety of topics relating to health and injury issues that Winter Olympic athletes may face. Experts are available for interviews by phone, webcam or satellite uplink from the...
6-Feb-2014 3:00 PM EST

Penn Medicine Surgeons Available to Discuss the Robotic Surgery Dr. Drew Chose to Treat His Prostate Cancer

25-Sep-2013 3:40 PM EDT

Penn Medicine Experts Available for Comment on Latest Research at SLEEP 2013

28-May-2013 11:00 AM EDT

Penn Health Policy Experts to Convene for Discussion on SCOTUS Ruling; Interviews Available

27-Jun-2012 4:20 PM EDT

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