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Baylor Study Reveals Oxidized Mitochondrial DNA Induces Interferon Production in Lupus Patients


Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response. The study...
13-Apr-2016 3:05 PM EDT Add to Favorites

UCLA Scientists Reveal How Osteopontin Ablation Ameliorates Muscular Dystrophy


Removing an immunomodulatory protein called osteopontin improves the symptoms of mice with muscular dystrophy by changing the type of macrophages acting on damaged muscle tissue, according to a paper published in The Journal of Cell Biology. The...
12-Apr-2016 3:00 PM EDT Add to Favorites

Face- and Eye-Muscle Research Sheds New Light on Duchenne Muscular Dystrophy


Researchers at Basel University Hospital in Switzerland investigate the biochemical and physiological characteristics of orbicularis oculi, a group of facial muscles that control the eyelids and are selectively spared or involved in...
4-Apr-2016 12:45 PM EDT Add to Favorites

How a Metabolic Pathway Promotes Breast Cancer Metastasis


A metabolic pathway that is up-regulated in some breast cancers promotes the disease’s progression by activating a signaling protein called Arf6, according to a paper published in The Journal of Cell Biology. The study, “P53- and mevalonate...
6-Apr-2016 4:05 PM EDT Add to Favorites

“Transient Contractions” in Urinary Bladder May Lead to Therapeutic Interventions for Bladder Dysfunction


Researchers at the University of Vermont College of Medicine have made a discovery on just how we know when to empty our bladders, which may have the potential to lead to new therapeutic interventions for bladder dysfunction. The study, “Transient...
28-Mar-2016 12:00 AM EDT Add to Favorites

ROBO1 Helps Cells Put Up Stiff Resistance


A protein called ROBO1 may delay the progression of breast cancer, according to a paper published in The Journal of Cell Biology. The study, “Loss of miR-203 regulates cell shape and matrix adhesion through ROBO1/Rac/FAK in response to...
8-Mar-2016 1:05 PM EST Add to Favorites

Decrypting a Collagen’s Role in Schizophrenia


A small peptide generated from a collagen protein may protect the brain from schizophrenia by promoting the formation of neuronal synapses, according to a paper published in The Journal of Cell Biology. The study, “Collagen-Derived Matricryptins...
8-Mar-2016 5:05 PM EST Add to Favorites

New Insights into Epilepsy Drug Retigabine


A recent study published ahead of print in the Journal of General Physiology has revealed new insights into Retigabine, a known pharmacological treatment for epilepsy.
18-Feb-2016 4:00 AM EST Add to Favorites

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