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Why KID Syndrome Patients Experience Different Sets of Symptoms

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A team of New York-based researchers has compared the effects of two disease-causing mutations, potentially explaining why patients with the rare genetic disorder keratitis-ichthyosis-deafness (KID) syndrome can experience different sets of...
27-Jun-2016 10:05 AM EDT Add to Favorites

Michel C. Nussenzweig Wins 2016 Robert Koch Award

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Michel C. Nussenzweig has won the 2016 Robert Koch Award, one of Germany’s most prestigious scientific prizes, honoring extraordinary accomplishments in infectious disease research. Nussenzweig will share the €100,000 prize with Alberto...
22-Jun-2016 3:30 PM EDT Add to Favorites

Mobilizing Mitochondria May Be Key to Regenerating Damaged Neurons

Researchers at the National Institute of Neurological Disorders and Stroke have discovered that boosting the transport of mitochondria along neuronal axons enhances the ability of mouse nerve cells to repair themselves after injury. The study,...
7-Jun-2016 2:00 PM EDT Add to Favorites

Researchers Uncover New Mode of Action for HUMIRA in Rheumatoid Arthritis Patients

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Researchers from University College London have discovered that the widely used antiinflammatory drug HUMIRA doesn’t just work by inhibiting its target protein, TNF, but by enhancing a particular function of TNF in rheumatoid arthritis patients....
1-Jun-2016 10:00 AM EDT Add to Favorites

A Combined Approach to Treating Metastatic Melanoma

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Oncologists at the Fred Hutchinson Cancer Research Center have successfully treated a patient with metastatic melanoma by combining two different types of immunotherapy. Cassian Yee and colleagues describe their approach in a paper, “Combined...
25-May-2016 11:00 AM EDT Add to Favorites

Mouse Study Links Heart Regeneration to Telomere Length

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Researchers at the Spanish National Center for Cardiovascular Research have discovered that the ends of heart muscle cell chromosomes rapidly erode after birth, limiting the cells’ ability to proliferate and replace damaged heart tissue. The...
25-May-2016 12:05 PM EDT Add to Favorites

Baylor Study Reveals Oxidized Mitochondrial DNA Induces Interferon Production in Lupus Patients

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Researchers at the Baylor Institute for Immunology Research have discovered that the neutrophils of systemic lupus erythematosus (SLE) patients release oxidized DNA from their mitochondria that can stimulate an unwanted immune response. The study...
13-Apr-2016 3:05 PM EDT Add to Favorites

UCLA Scientists Reveal How Osteopontin Ablation Ameliorates Muscular Dystrophy

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Removing an immunomodulatory protein called osteopontin improves the symptoms of mice with muscular dystrophy by changing the type of macrophages acting on damaged muscle tissue, according to a paper published in The Journal of Cell Biology. The...
12-Apr-2016 3:00 PM EDT Add to Favorites

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