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Advanced Development of Primary Pancreatic Organoid Tumor Models for High-Throughput Phenotypic Drug Screening

A multidisciplinary team of scientists share recent advancements in innovative in-vitro cancer biology methods for screening drug-like molecules in cancer tissue relevant models in a new report published online ahead-of-print at SLAS Discovery....
16-Apr-2018 5:05 AM EDT Add to Favorites

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Automated Preparation of MS-Sensitive Fluorescently-Labeled N-Glycans with a Commercial Pipetting Robot

A new original research report available ahead-of-print at SLAS Technology demonstrates the semi-automation of a GlycoWorks RapiFluor-MS (RFMS) Kit using a pipetting robot to improve life sciences research productivity.
2-Apr-2018 3:05 AM EDT Add to Favorites

Fully Automated Pipetting Sorting System for Different Morphological Phenotypes of Zebrafish Embryos

Breitwieser and colleagues of the Karlsruhe Institute of Technology (Germany) describe a fully automated high-throughput sorting system for zebrafish embryo phenotypes that benefits high-throughput screening by saving time and improving accuracy.
22-Mar-2018 4:05 AM EDT Add to Favorites

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Protein Nutrition for Cells and Organisms: Can We Use it to Treat Diseases?

A review article by Prof. Stefan Broer, Ph.D., highlights opportunities and challenges in using amino acid transporters as drug targets. Amino Acid Transporters as Disease Modifiers and Drug Targets provides an overview of methods used to identify...
16-Mar-2018 5:05 AM EDT Add to Favorites

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Using Microscale Thermophoresis to Characterize Hits from High-Throughput Screening: A European Lead Factory Perspective

A perspective article in the March 2018 issue of SLAS Discovery from the biology group at the European Screening Centre Newhouse details how the European Lead Factory (ELF), a large publicly accessible drug discovery platform, uses microscale...
15-Feb-2018 5:05 AM EST Add to Favorites

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SLAS Scientific Journals Honor Achievement by Authors and Reviewers

SLAS Discovery (formerly the Journal of Biomolecular Screening) and SLAS Technology (formerly the Journal of Laboratory Automation), both published by SLAS (Society of Laboratory Automation and Screening) in partnership with SAGE Publishing, hosted...
2-Feb-2018 6:05 AM EST Add to Favorites

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A Phenotypic High-Throughput Screen to Identify Modulators that Improve Mutant Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) Activity

A phenotypic high-throughput screen to identify modulators that improve mutant cystic fibrosis transmembrane conductance regulator (CFTR) activity is described in the SLAS Discovery February 2018 front cover feature article by Giuliano and...
29-Jan-2018 9:05 AM EST Add to Favorites

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Announcing the 2018 SLAS Technology Ten: Translating Life Sciences Innovation

“The 2018 SLAS Technology Ten represent some of the most innovative scientific achievements that were featured in SLAS Technology in the past 12 months,” says Editor-in-Chief Edward Kai-Hua Chow, PhD (National University of Singapore).
24-Jan-2018 6:05 AM EST Add to Favorites


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