Scripps Research Institute
La Jolla, CA USA

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Scripps Research Institute Scientists Shed Light on Cause of Spastic Paraplegia

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Scientists at The Scripps Research Institute (TSRI) have discovered that a gene mutation linked to hereditary spastic paraplegia, a disabling neurological disorder, interferes with the normal breakdown of triglyceride fat molecules in the brain. The...
29-Sep-2014 9:05 AM EDT

Surprising Diversity of Antibody Family Provides Clues for HIV Vaccine Design

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Scientists at The Scripps Research Institute (TSRI) have described how a single family of antibodies that broadly neutralizes different strains of HIV has evolved remarkably diverse structures to attack a vulnerable site on the virus. The findings...
24-Sep-2014 10:00 AM EDT

Scripps Research Institute Scientists Awarded $7.9 Million to Develop Artificial Immune System

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Scientists from both campuses of The Scripps Research Institute (TSRI) have been awarded a total of $7.9 million from the Defense Advanced Research Projects Agency (DARPA) of the U.S. Department of Defense. The two teams will build what is, in...
24-Sep-2014 12:00 PM EDT

MS Drug Candidate Shows New Promise

Positive new data have been released on a drug candidate, RPC1063, for relapsing multiple sclerosis that was first discovered and synthesized at The Scripps Research Institute (TSRI).
19-Sep-2014 12:05 AM EDT

Scripps Research Institute Chemists Modify Antibiotic to Vanquish Resistant Bacteria

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Scientists at The Scripps Research Institute (TSRI) have devised a new antibiotic based on vancomycin that is powerfully effective against vancomycin-resistant strains of MRSA and other disease-causing bacteria.
17-Sep-2014 3:50 PM EDT

Team Identifies Important Regulators of Immune Cell Response

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Scientists from the Florida campus of The Scripps Research Institute and the La Jolla Institute for Allergy and Immunology have developed a more effective method to determine how T cells differentiate into specialized cell types.
4-Sep-2014 1:00 PM EDT

Scripps Florida Scientists Make Diseased Cells Synthesize Their Own Drug

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In a new study that could lead to many new medicines, scientists from the Florida campus of The Scripps Research Institute have adapted a chemical approach to turn diseased cells into unique manufacturing sites for molecules that can treat a form of...
2-Sep-2014 12:00 PM EDT

Scripps Research Institute Scientists Link Alcohol-Dependence Gene to Neurotransmitter

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Scientists at The Scripps Research Institute solved the mystery of why a specific signaling pathway can be associated with alcohol dependence. The new research shows the gene, Nf1, regulates gamma-aminobutyric acid (GABA), a neurotransmitter that...
27-Aug-2014 1:00 PM EDT

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