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Scripps Florida Scientists’ Structural Discoveries Could Aid in Better Drug Design


Scientists from The Scripps Research Institute Florida campus have uncovered the structural details of how some proteins interact to turn two different signals into a single integrated output, findings that could aid future drug design.
25-Aug-2015 8:00 AM EDT

New Study by TSRI and Janssen Makes Major Advance Toward More Effective, Long-Lasting Flu Vaccine


Scientists from The Scripps Research Institute (TSRI) and the Janssen Pharmaceutical Companies of Johnson & Johnson (Janssen) have found a way to induce antibodies to fight a wide range of influenza subtypes—work that could one day eliminate the...
24-Aug-2015 8:05 AM EDT

TSRI Scientists Uncover Surprising Mechanism Behind Antibiotic-Resistant Bacteria


Scientists at The Scripps Research Institute have discovered that the human pathogen Staphylococcus aureus develops resistance to the antibiotic arylomycin by “switching on” a previously uncharacterized set of genes, explaining higher antibiotic...
20-Aug-2015 10:05 AM EDT

International Team Discovers the Ancient Origins of Deadly Lassa Virus


Working as part of an international team in the United States and West Africa, a researcher at The Scripps Research Institute has published new findings showing the ancient roots of the deadly Lassa virus, a relative of Ebola virus, and how Lassa...
11-Aug-2015 3:05 PM EDT

Team Finds a Better Way to Engineer Therapeutic Proteins into Antibodies


A team led by scientists at The Scripps Research Institute has devised an improved method to re-engineer proteins into larger proteins, such as antibodies, to improve their usefulness.
12-Aug-2015 2:05 PM EDT

Scripps Florida Scientists Determine How Antibiotic Gains Cancer-Killing Sulfur Atoms


With implications for future drug design, scientists The Scripps Research Institute’s Florida camps have shown an unprecedented mechanism for how a natural antibiotic with antitumor properties incorporates sulfur into its molecular structure, an...
10-Aug-2015 3:05 PM EDT

TSRI Chemists Report Nicotine-Chomping Bacteria May Hold Key to Anti-Smoking Therapy


A study from scientists at The Scripps Research Institute explores a bacterial enzyme that might be used as a drug candidate to help people quit smoking. The research shows this enzyme can be recreated in lab settings and possesses a number of...
6-Aug-2015 1:05 PM EDT

Scripps Florida Scientists Show How Aging Cripples the Immune System, Suggesting Benefits of Antioxidants


Scientists from the Florida campus of The Scripps Research Institute have shown how aging cripples the production of new immune cells, decreasing the immune system’s response to vaccines and putting the elderly at risk of infection.
3-Aug-2015 2:05 PM EDT

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