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How Colorectal Cancer Cells Spread to the Liver

A new study by Sanford Burnham Prebys Medical Discovery Institute (SBP) researchers helps explain the connection between a tumor suppressor called protein kinase C zeta (PKC zeta) and metastatic colorectal cancer.
20-Apr-2018 12:00 PM EDT Add to Favorites


San Diego Leaders, Researchers Announce Milestone Grant as Alzheimer's Crisis Widens

A coalition of brain scientists and civic leaders, including Mayor Kevin Faulconer and county Supervisors Dianne Jacob and Kristin Gaspar, announced that the federal government has awarded a $1.3 million grant to Sanford Burnham Prebys Medical...
20-Apr-2018 10:05 AM EDT Add to Favorites


Study Finds How Fat Tissue Shunts Energy to Tumors

Sanford Prebys Medical Discovery Institute (SBP) researchers recently discovered that that inactivation of a protein called p62 in fat cells fuels aggressive, metastatic prostate cancer in mice. The findings suggest that mTOR inhibitors currently...
6-Apr-2018 12:00 AM EDT Add to Favorites


Evan Snyder Elected to Association of American Physicians

Evan Y. Snyder, M.D., Ph.D., professor and founding director, Center for Stem Cells & Regenerative Medicine at Sanford Burnham Prebys Medical Discovery Institute (SBP) and professor at the University of California San Diego, has been elected to...
4-Apr-2018 12:00 PM EDT Add to Favorites


The Brain’s Immune System May Be Key to New Alzheimer’s Treatments

SBP researchers have revealed how TREM2, a receptor found on immune cells in the brain, interacts with toxic amyloid beta proteins to restore neurological function. The research suggests boosting TREM2 levels in the brain may prevent or reduce the...
5-Mar-2018 4:00 PM EST Add to Favorites


Controlling Ceramides Could Help Treat Heart Disease

SBP researchers have discovered that accumulation of ceramides—a type of lipid (fat)— plays a crucial role in lipotoxic cardiomyopathy (LCM)—a heart condition that often occurs in patients with diabetes and obesity. The study, published today...
5-Mar-2018 11:00 AM EST Add to Favorites


Novel Genome Platform Reveals New HIV Targets

SBP researchers have developed the first ever high-throughput, genome-scale imaging-based approach to investigate protein stability. The method has been used to identify several previously unknown human proteins that HIV degrades to enhance its...
22-Feb-2018 8:00 AM EST Add to Favorites


Discovery May Advance Neural Stem Cell Treatments for Brain Disorders

New research from Sanford Burnham Prebys Medical Discovery Institute (SBP) reveals a novel gene regulatory system that may advance stem cell therapies and gene-targeting treatments for neurological diseases such as Alzheimer’s disease,...
24-Jan-2018 9:00 AM EST Add to Favorites

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