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First Comprehensive Analysis of the Woolly Mammoth Genome Completed

The first comprehensive analysis of the woolly mammoth genome reveals extensive genetic changes that allowed mammoths to adapt arctic life, including skin and hair development, insulin signaling, fat biology, and even traits such as small ears and...
2-Jul-2015 12:00 PM EDT

UChicago Medicine, Little Company of Mary Expand Pediatric Partnership

The University of Chicago Medicine and Little Company of Mary Hospital and Health Care Centers are partnering to expand care for infants and children by developing a subspecialty center on the community hospital’s Evergreen Park campus that will...
1-Jul-2015 2:00 PM EDT

New Tool Brings Standards to Epigenetic Studies

Scientists from the University of Chicago have developed a new technique that calibrates a commonly-used tool in epigenetic experiments with an internal standard - dramatically improving accuracy and the development of therapeutics against diseases...
4-Jun-2015 5:00 AM EDT

Available Genetic Data Could Help Doctors Make Better Use of Cardiovascular Drugs

Few heart specialists make use of published information about interactions between drugs used to treat cardiovascular disease and the genetic variations that affect how patients respond to them. So physicians at U Chicago and Stanford combed through...
27-May-2015 4:00 PM EDT

Disrupting Cancer Pathway Could Enhance New Immunotherapies

Understanding how to overrule a signaling pathway that can cause treatments to fail in metastatic melanoma patients should help physicians extend the benefits of recently approved immunity-boosting drugs known as checkpoint inhibitors to more...
5-May-2015 2:05 PM EDT

Genetic Changes to Basic Developmental Processes Evolve More Frequently Than Thought

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Newly evolved genes can rapidly assume control over fundamental functions during early embryonic development, report scientists from the University of Chicago. The findings suggest that evolutionary changes to the genetics of fundamental biological...
6-May-2015 11:05 AM EDT

Cells Amplify Messenger RNA Levels to Set Protein Levels

Messenger RNA (mRNA) levels dictate most differences protein levels in fast-growing cells when analyzed using statistical methods that account for noise in the data, according to a new study by researchers from the University of Chicago and Harvard...
5-May-2015 10:05 AM EDT

In Late Post-Surgical Colon ‘Leaks,’ Finger Points to Microbes

Post-surgical leaks that develop after a segment of the colon has been removed and stitched back together often are caused not by negligence or technical error but by bacteria in the bowel that elude antibiotics, according to new evidence about this...
4-May-2015 11:30 AM EDT

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