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Cross Talk Between Hormone Receptors Has Unexpected Effects

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Although the estrogen receptor is considered dominant in breast cancer, the progesterone receptor assumes control when both receptors are present and exposed to estrogens and progestins. Then, the progesterone receptor drives estrogen receptor...
23-Jun-2016 4:00 PM EDT Add to Favorites

Cancer, Violence Among Top Health Concerns for Chicago's South Siders

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Residents on the South Side say cancer, violence prevention and sexually transmitted infections are among their top health concerns, according to the latest comprehensive assessment conducted by the University of Chicago Medicine. The 2016...
22-Jun-2016 9:05 AM EDT Add to Favorites

Microbiota Affect the Rate of Transplant Acceptance and Rejection

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Researchers from the University of Chicago have shown that microbiota—the bacteria, viruses and other microbes living on the skin and in the digestive system—play an important role in the body’s ability to accept transplanted skin and other...
14-Jun-2016 11:05 AM EDT Add to Favorites

Modern Mussel Shells Much Thinner Than 50 Years Ago

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Shells of California mussels collected from the Pacific Ocean off the coast of Washington in the 1970s are on average 32 percent thicker than modern specimens, according to a new study published by University of Chicago biologists.
14-Jun-2016 11:00 AM EDT Add to Favorites

Radiation and Vaccination Can Magnify Effects of Immunotherapy

By combining local radiation therapy and anti-cancer vaccines with checkpoint inhibitors, researchers from the University of Chicago – working with mice – were able to increase the response rate for these new immunotherapy agents. This sequence...
8-Jun-2016 1:00 PM EDT Add to Favorites

Genomic Data Commons at University of Chicago Heralds New Era of Data Sharing for Cancer Research

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The Genomic Data Commons (GDC), a next-generation platform that enables unprecedented data access, analysis and sharing for cancer research, publicly launched at the University of Chicago on June 6, opening the door to discoveries for this complex...
6-Jun-2016 4:05 PM EDT Add to Favorites

Novel Immunotherapy Approach Shows Promise in Blood Cancers

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Cancer researchers show that injecting substances that mimic tumor-cell DNA into the bloodstream, they can stimulate the STING pathway to provoke a life-extending immune response in mice with acute myeloid leukemia. This is the first demonstration...
31-May-2016 9:05 AM EDT Add to Favorites

Stopping Cancer in Its Tracks

Inhibiting autophagy, the process cells use to degrade large intra-cellular cargo, effectively blocks tumor cell migration and breast cancer metastasis in tumor models. Metastasis is responsible for 90 percent of cancer deaths. There are approved...
9-May-2016 6:05 PM EDT Add to Favorites

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