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New Study Helps Explain Links Between Sleep Loss and Diabetes

Lack of sleep can elevate levels of free fatty acids in the blood, accompanied by temporary pre-diabetic conditions in healthy young men. Getting enough sleep could help counteract the current epidemics of diabetes and obesity.
16-Feb-2015 2:10 PM EST

Seasonal Flu Vaccine Induces Antibodies That Protect Against H7N9 Avian Flu

Antibodies that protect against H7N9 avian flu, which emerged in China in 2013 and sparked fears of a global pandemic, have been isolated in individuals who received seasonal flu vaccinations and appear to broadly neutralize H7 viruses.
12-Feb-2015 10:00 AM EST

New Screening Tool Could Speed Development of Ovarian Cancer Drugs


Researchers have built a model system that uses multiple cell types from patients to rapidly test compounds that could block the early steps in the spread of ovarian cancer. This has enabled them to identify small molecules that can inhibit adhesion...
9-Feb-2015 5:00 PM EST

microRNAs Can Limit Cancer Spread

In cancer patients with limited spread, certain microRNAs suppress tumor cells’ ability to adhere to other cell types, invade tissues and migrate to distant sites, the hallmarks of metastasis. This could predict how aggressively a tumor can spread...
2-Feb-2015 12:00 PM EST

Low-Frequency Deep Brain Stimulation Improves Difficult-to-Treat Parkinson’s Symptoms

Parkinson’s disease patients treated with low-frequency deep brain stimulation show significant improvements in swallowing dysfunction and freezing of gait over typical high-frequency treatment.
27-Jan-2015 3:00 PM EST

Modern Genetics Confirm Ancient Relationship Between Fins and Hands


Efforts to connect the evolutionary transition from fish fins to wrist and fingers with the genetic machinery for this adaptation have fallen short because they focused on the wrong fish. Now, researchers describe the genetic machinery for autopod...
19-Dec-2014 1:00 PM EST

RNA Measurements May Yield Less Insight About Gene Expression Than Assumed

The majority of RNA expression differences between individuals have no connection to the abundance of a corresponding protein, report scientists from the University of Chicago in Science. The results point to a yet-unidentified gene regulatory...
16-Dec-2014 12:00 PM EST

Early Trial of New Drug Shows Promise for Patients with Metastatic Triple-Negative Breast Cancer


In patients with metastatic triple-negative breast cancer, infusion of pembrolizumab produced durable responses in almost one out of five patients. One of the 27 patients had a complete response and four had a partial response. Seven more patients...
9-Dec-2014 10:00 AM EST

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