Children born with developmental disorders called cohesinopathies can suffer severe consequences, including intellectual disabilities, limb shortening, craniofacial anomalies, and slowed growth. Researchers know which mutations underlie some...
10/2/2013 11:00 AM EDT
When egg and sperm combine, the new embryo bustles with activity. Its cells multiply so rapidly they largely ignore their DNA, other than to copy it and to read just a few essential genes. The embryonic cells mainly rely on molecular instructions...
8/13/2013 2:00 PM EDT
A decade ago, gene expression seemed so straightforward: genes were either switched on or off. Not both. Then in 2006, a blockbuster finding reported that developmentally regulated genes in mouse embryonic stem cells can have marks associated with...
8/8/2013 1:00 PM EDT
A little-studied factor known as the Little Elongation Complex (LEC) plays a critical and previously unknown role in the transcription of small nuclear RNAs (snRNA), according to a new study led by scientists at the Stowers Institute for Medical...
8/5/2013 2:00 PM EDT
Stowers investigators use genetics and live cell imaging to illuminate molecular mechanisms that position the cell division machinery in growing tissues.
7/18/2013 5:45 PM EDT
Genomic imprinting maintains a reserve pool of blood-forming stem cells in mouse bone marrow
7/15/2013 8:15 AM EDT
Stowers investigators discover how an unusual interplay of signaling pathways shapes a critical eye structure
5/14/2013 1:30 PM EDT
Stowers Institute Investigator Peter Baumann, Ph.D., has been appointed to the prestigious position of Howard Hughes Medical Institute (HHMI) investigator.
5/9/2013 6:00 AM EDT