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Researchers Design “Evolutionary Trap” to Thwart Drug Resistance

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Using theoretical and experimental approaches, researchers at the Stowers Institute for Medical Research have developed a two-pronged strategy that uses an evolving cell population’s adaptive nature against it.
6-Feb-2015 1:00 PM EST

Cutting the Ties That Bind

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The development of a new organism from the joining of two single cells is a carefully orchestrated endeavor. But even before sperm meets egg, an equally elaborate set of choreographed steps must occur to ensure successful sexual reproduction. Those...
22-Oct-2014 4:00 PM EDT

New Insight That “Mega” Cells Control the Growth of Blood-Producing Cells

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While megakaryocytes are best known for producing platelets that heal wounds, these “mega” cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research....
17-Oct-2014 12:00 PM EDT

Misfolded Proteins Clump Together in a Surprising Place

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Scientists at the Stowers Institute for Medical Research have made a surprising finding about the aggregates of misfolded cellular proteins that have been linked to aging-related disorders such as Parkinson’s disease. The researchers report their...
14-Oct-2014 4:00 PM EDT

How an Ancient Vertebrate Uses Familiar Tools to Build a Strange-Looking Head

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Investigator and Scientific Director Robb Krumlauf, Ph.D. and colleagues show that the sea lamprey Petromyzon marinus, a survivor of ancient jawless vertebrates, exhibits a pattern of gene expression that is reminiscent of its jawed cousins, who...
11-Sep-2014 1:00 PM EDT

“K-to-M” Histone Mutations: How Repressing the Repressors May Drive Tissue-Specific Cancers

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A paper from a laboratory at the Stowers Institute of Medical Research reports the first animal model created to assess the molecular effects of two different histone H3.3 mutations in the fruit fly Drosophila. The study from a team led by...
28-Aug-2014 5:35 PM EDT

Stowers Researchers Reveal Molecular Competition Drives Adult Stem Cells to Specialize

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Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn-out or damaged organs and...
5-Aug-2014 1:00 PM EDT

It Takes Two to Court

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Researchers at the Stowers Institute for Medical Research, have identified the functions of two classes of pheromone receptors, and found pheromones crucial to triggering the mating process in mice.
25-Jul-2014 8:00 AM EDT

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