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Molecular Signature of “Trailblazer” Neural Crest Cells Gives Insight Into Development and Cancer

In a study published online in the journal eLife, the researchers identified a molecular signature of approximately 1300 genes differentially expressed in an aggressive subset of migrating neural crest cells termed as “trailblazers” in a...
18-Dec-2017 4:50 PM EST Add to Favorites


Marriage of Microscopy Techniques Reveals 3D Structure of Critical Protein Complex

Researchers at the Stowers Institute for Medical Research have solved the three-dimensional structure of a complex that is essential for the correct sorting of chromosomes into eggs and sperm during reproductive cell division or meiosis.
2-Aug-2017 2:35 PM EDT Add to Favorites


Cancer Cells May Streamline Their Genomes in Order to Proliferate More Easily

Research from the Stowers Institute provides evidence suggesting that cancer cells might streamline their genomes in order to proliferate more easily. The study, conducted in both human and mouse cells, shows that cancer genomes lose copies of...
19-Jun-2017 5:05 AM EDT Add to Favorites


Selfish Gene Acts as Both Poison and Antidote to Eliminate Competition

Researchers from the Stowers Institute for Medical Research in collaboration with Fred Hutchinson Cancer Research Center researchers have identified an unprecedented genetic survival strategy that would be right at home in an Agatha Christie murder...
20-Jun-2017 6:05 AM EDT Add to Favorites


Genetic Cross-Talk Key to Cell Balance

In a study published in the June 5, 2017, issue of the Proceedings of the National Academy of Sciences, Stowers scientists Bony De Kumar, Ph.D., and Robb Krumlauf, Ph.D., provide evidence of direct cross-regulatory feedback, or cross-talk, between...
31-May-2017 2:00 PM EDT Add to Favorites


Polymerases Pause to Help Mediate the Flow of Genetic Information

Stop-and-go traffic is typically a source of frustration, an unneccesary hold-up on the path from point A to point B. But when it comes to the molecular machinery that copies our DNA into RNA, a stop right at the beginning of the path may actually...
17-May-2017 9:00 AM EDT Add to Favorites


Uncovering New Relationships and Organizational Principles in Protein Interaction Networks

Proteins, those basic components of cells and tissues, carry out many biological functions by working with partners in networks. The dynamic nature of these networks – where proteins interact with different partners at different times and in...
6-Mar-2017 2:00 PM EST Add to Favorites

Possible Key to Regeneration Found in Planaria’s Origins

A new report from the Stowers Institute for Medical Research chronicles the embryonic origins of planaria, providing new insight into the animal's remarkable regenerative abilities.
13-Feb-2017 1:05 PM EST Add to Favorites

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