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The Worm Has Turned: New Research Uncovers Processes Driving Planarian Stem Cell Differentiation in Living Tissues

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In two new studies, researchers in the laboratory of Howard Hughes Medical Institute Investigator Alejandro Sánchez Alvarado, Ph.D., at the Stowers Institute for Medical Research explore the intricate processes at work when stem cells differentiate...
16-Dec-2015 12:05 PM EST Add to Favorites

Potential Biochemical Mechanism Underlying Long-Term Memories Identified

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During the holidays, we often remember the past and create new memories. But, why do some memories fade away while others last forever? Scientists at the Stowers Institute for Medical Research have identified a possible biochemical mechanism by...
2-Dec-2015 4:50 PM EST Add to Favorites

How a Genetic Locus Protects Adult Blood-Forming Stem Cells

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A particular location in DNA, called the Dlk1-Gtl2 locus, plays a critical role in protecting hematopoietic, or blood-forming, stem cells—a discovery revealing a critical role of metabolic control in adult stem cells, and providing insight...
25-Nov-2015 2:05 PM EST Add to Favorites

Protein Complex Links Cellular Metabolism to Gene Expression, Offers Potential Therapeutic Target

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Researchers in the Workman Lab at the Stowers Institute for Medical Research have identified a link between cellular metabolism and gene expression, one with potentially far-reaching implications for cancer risk prediction and treatment.
26-Oct-2015 6:05 AM EDT Add to Favorites

Innovative Imaging Technique Reveals New Cellular Secrets

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A team of researchers from the Stowers Institute for Medical Research and the University of Colorado Boulder has devised a novel optical technique — a combination of structured illumination microscopy (SIM) and single-particle averaging (SPA) —...
11-Sep-2015 10:30 AM EDT Add to Favorites

Orchestrating Hair Cell Regeneration: A Supporting Player’s Close-Up

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A new study in Developmental Cell, from Stowers Institute for Medical Research Associate Investigator Tatjana Piotrowski, Ph.D., zeros in on an important component in fish: the support cells that surround centrally-located hair cells in each...
10-Jul-2015 5:05 PM EDT Add to Favorites

Stress Triggers Key Molecule to Halt Transcription of Cell’s Genetic Code

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Researchers at the Stowers Institute have shown that a molecule called elongin A assists with transcription.
27-May-2015 3:00 PM EDT Add to Favorites

Stowers Investigator Elected to American Academy of Arts and Sciences

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Sánchez Alvarado, known for his groundbreaking work on the biology of the planaria—a flatworm model organism known for its regenerative abilities, has been elected to the American Academy of Arts and Sciences.
22-Apr-2015 10:00 AM EDT Add to Favorites

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