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New Insight That “Mega” Cells Control the Growth of Blood-Producing Cells


While megakaryocytes are best known for producing platelets that heal wounds, these “mega” cells found in bone marrow also play a critical role in regulating stem cells according to new research from the Stowers Institute for Medical Research....
17-Oct-2014 12:00 PM EDT

Misfolded Proteins Clump Together in a Surprising Place


Scientists at the Stowers Institute for Medical Research have made a surprising finding about the aggregates of misfolded cellular proteins that have been linked to aging-related disorders such as Parkinson’s disease. The researchers report their...
14-Oct-2014 4:00 PM EDT

How an Ancient Vertebrate Uses Familiar Tools to Build a Strange-Looking Head


Investigator and Scientific Director Robb Krumlauf, Ph.D. and colleagues show that the sea lamprey Petromyzon marinus, a survivor of ancient jawless vertebrates, exhibits a pattern of gene expression that is reminiscent of its jawed cousins, who...
11-Sep-2014 1:00 PM EDT

“K-to-M” Histone Mutations: How Repressing the Repressors May Drive Tissue-Specific Cancers


A paper from a laboratory at the Stowers Institute of Medical Research reports the first animal model created to assess the molecular effects of two different histone H3.3 mutations in the fruit fly Drosophila. The study from a team led by...
28-Aug-2014 5:35 PM EDT

Stowers Researchers Reveal Molecular Competition Drives Adult Stem Cells to Specialize


Adult organisms ranging from fruit flies to humans harbor adult stem cells, some of which renew themselves through cell division while others differentiate into the specialized cells needed to replace worn-out or damaged organs and...
5-Aug-2014 1:00 PM EDT

It Takes Two to Court


Researchers at the Stowers Institute for Medical Research, have identified the functions of two classes of pheromone receptors, and found pheromones crucial to triggering the mating process in mice.
25-Jul-2014 8:00 AM EDT

Finding the Target: How Timing Is Critical in Establishing an Olfactory Wiring Map


In the April 11, 2014 issue of Science, Associate Investigator C. Ron Yu, Ph.D. and colleagues at the Stowers Institute of Medical Research identify a developmental window during which olfactory neurons of newborn mice can form a proper wiring map....
3-Apr-2014 9:30 AM EDT

Planaria Deploy an Ancient Gene Expression Program in the Course of Organ Regeneration


In the April 15, 2014 issue of the online journal eLife, Stowers Institute for Medical Research Investigator Alejandro Sánchez Alvarado and colleagues report the identification of genes that worms use to rebuild an amputated pharynx.
10-Apr-2014 11:00 AM EDT

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