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Immunotherapy, Gene Editing Advances Extend to Type 1 Diabetes

Advances in engineering T cells to treat cancer are paving the way for new immunotherapies targeted at autoimmune diseases, including type 1 diabetes. Now, researchers are also investigating therapies that reprogram T cells to “turn down” an...
13-Dec-2017 12:05 PM EST Add to Favorites

Immunotherapy Drug for Rheumatoid Arthritis Nearly Eliminates Severe Acute Graft-Versus-Host Disease after Hematopoietic Stem Cell Transplant


Results from a phase 2 clinical trial, presented by Seattle Children’s Research Institute at the 59th American Society of Hematology (ASH) Annual Meeting, show that the drug Abatacept (Orencia) nearly eliminated life-threatening severe acute...
7-Dec-2017 2:00 PM EST Add to Favorites

In Scientific First, Seattle Children's Researchers Engineer B Cells to Treat Disease


Scientists at Seattle Children’s Research Institute have unlocked the ability to engineer B cells, uncovering a potential new cell therapy that could someday prevent and cure disease.
5-Dec-2017 4:05 PM EST Add to Favorites

Seattle Children's Opens First CAR T-Cell Immunotherapy Trial in the U.S. for Children and Young Adults With Leukemia that Targets CD22 and CD19 Proteins Simultaneously


Seattle Children’s has opened the first chimeric antigen receptor (CAR) T-cell immunotherapy trial in the U.S. for children and young adults with relapsed or refractory CD19- and CD22-positive acute lymphoblastic leukemia (ALL) that will...
16-Nov-2017 9:00 AM EST Add to Favorites

Seattle Children’s Launches $1 Billion Fundraising Campaign to Transform Children’s Health

Yes Campaign Banner_Makenna Schwab.jpg

Seattle Children’s today launched a $1 billion initiative, It Starts With Yes: The Campaign for Seattle Children’s, with a bold vision: to transform children’s health. It Starts With Yes is the largest campaign in Seattle Children’s 110-year...
15-Nov-2017 10:05 AM EST Add to Favorites

Researchers Put Youth Sports Safety and Concussion Awareness Ahead of the Game With Novel Program


Seattle Children’s researchers will launch an innovative program in early 2018 aimed at shifting the culture of safety in youth sports and building concussion awareness during competitive play with the help of pre-game safety huddles.
8-Nov-2017 10:20 AM EST Add to Favorites

Promising Drug Combination Silences the Rage of Graft-Versus-Host Disease


To pass the nearly 180 days she was a patient in Seattle Children’s Cancer Unit with graft-versus-host disease (GVHD), London Bowater took orders from her doctors, nurses and other patients and families for friendship bracelets that she would...
29-Sep-2017 1:05 PM EDT Add to Favorites

Seattle Children's Opens CD22 CAR T-Cell Immunotherapy Trial for Children and Young Adults Whose Leukemia Escapes CD19 CAR T-Cell Therapy

After seeing promising results in phase 1 of the Pediatric Leukemia Adoptive Therapy (PLAT-02) trial with 93 percent of patients with relapsed or refractory acute lymphoblastic leukemia (ALL) achieving complete initial remission, researchers at...
27-Jul-2017 9:00 AM EDT Add to Favorites

Our Experts on Newswise

First Day of School Health Checklist: What Every Parent Should Know

Experts at Seattle Children's Hospital have put together a Healthy Child Checklist to ensure that children "“ and parents "“ are prepared for the first day of school.
24-Jul-2009 1:00 PM EDT

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