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‘Sugar-Coated’ Microcapsule Eliminates Toxic Punch of Experimental Anti-Cancer Drug

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Johns Hopkins researchers have developed a sugar-based molecular microcapsule that eliminates the toxicity of an anticancer agent developed a decade ago at Johns Hopkins, called 3-bromopyruvate, or 3BrPA, in studies of mice with implants of human...
17-Dec-2014 3:35 PM EST

Multiple Allergic Reactions Traced to Single Protein

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Johns Hopkins and University of Alberta researchers have identified a single protein as the root of painful and dangerous allergic reactions to a range of medications and other substances. If a new drug can be found that targets the problematic...
16-Dec-2014 12:00 PM EST

Bacterial 'Bunches' Linked to Some Colorectal Cancers

Researchers from Johns Hopkins have found that dense mats of interacting bacteria, called biofilms, were present in the majority of cancers and polyps, particularly those on the right side of the colon. The presence of these bacterial bunches, they...
16-Dec-2014 3:00 PM EST

Amount of Mitochondrial DNA Predicts Frailty and Mortality

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New research from The Johns Hopkins University suggests that the amount of mitochondrial DNA (mtDNA) found in peoples’ blood directly relates to how frail they are medically. This DNA may prove to be a useful predictor of overall risk of frailty...
16-Dec-2014 12:00 PM EST

Stop That Scalpel: Many Kids With Open Bone Breaks Can Heal Safely Without Surgery

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Many children who sustain so-called open bone fractures in the forearm or lower leg can, and do, heal safely without surgery, according to the results of a small study led by investigators at the Johns Hopkins Children’s Center.
10-Dec-2014 2:30 PM EST

Brain Inflammation a Hallmark of Autism, Large-Scale Analysis Shows

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While many different combinations of genetic traits can cause autism, brains affected by autism share a pattern of ramped-up immune responses, an analysis of data from autopsied human brains reveals. The study, a collaborative effort between Johns...
10-Dec-2014 5:00 AM EST

Paying Attention Makes Touch-Sensing Brain Cells Fire Rapidly and in Sync

Whether we’re paying attention to something we see can be discerned by monitoring the firings of specific groups of brain cells. Now, new work from Johns Hopkins shows that the same holds true for the sense of touch. The study brings researchers...
9-Dec-2014 8:00 AM EST

Toughest Breast Cancer May Have Met Its Match

Triple-negative breast cancer is as bad as it sounds. The cells that form these tumors lack three proteins that would make the cancer respond to powerful, customized treatments. Instead, doctors are left with treating these patients with traditional...
8-Dec-2014 2:00 PM EST

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