La Jolla Institute for Allergy and Immunology
La Jolla, CA USA
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Sharpin Emerges From the Pack as a Regulator of Inflammation


It is normal—in fact necessary—for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage persists or is re-directed against one’s self, as...
2-Feb-2016 11:05 AM EST Add to Favorites

New Study Indicates Why Children Are Likelier to Develop Food Allergies


An estimated 15 million Americans suffer from food allergies, many of them children. These are non-trivial concerns, as food allergy or intolerance can cause symptoms ranging from a harmless skin rash to a potentially lethal anaphylactic shock. The...
25-Jan-2016 11:05 AM EST Add to Favorites

La Jolla Institute for Allergy and Immunology Team Receives $18 Million Consortium Grant


The La Jolla Institute for Allergy and Immunology (LJI) is pleased to announce that an international team led by LJI investigator Alessandro Sette, Ph.D., is one of four recipients of a Human Immune Profiling Consortium (HIPC) grant in 2015. With...
17-Dec-2015 2:05 PM EST Add to Favorites

HardTech Labs, La Jolla Institute Partner to Develop Health and Wellness Technology

HardTech Labs LLC (HTL) has partnered with La Jolla Institute for Allergy and Immunology (LJI) to establish a joint venture, HTL Life, that will converge HTL’s existing focus on software and hardware with LJI’s expertise in life sciences to...
10-Dec-2015 6:00 AM EST Add to Favorites

TET Proteins Help Maintain Genome Integrity


Members of the TET (short for ten-eleven translocation) family have been known to function as tumor suppressors for many years, but how they keep a lid on the uncontrolled cell proliferation of cancer cells had remained uncertain. Now, researchers...
9-Dec-2015 11:05 AM EST Add to Favorites

Matchmaker Lets Calcium Flow


The ebb and flow of intracellular calcium concentrations is a universal mode of communication in mammalian cells. Researchers at La Jolla Institute identified the matchmaker that brings two critical calcium channel components together, thus allowing...
6-Dec-2015 2:05 PM EST Add to Favorites

The Innate Immune System Modulates the Severity of Multiple Sclerosis


Multiple sclerosis, a debilitating neurological disease, is triggered by self-reactive T cells that successfully infiltrate the brain and spinal cord where they launch an aggressive autoimmune attack against myelin, the fatty substance that...
28-Oct-2015 11:05 AM EDT Add to Favorites

A Subpopulation of White Blood Cells Guards Against Tumor Lung Metastasis


Among foot soldiers on the immune front line is a subpopulation of white blood cells called “patrolling monocytes,” whose job is to cruise the bloodstream, cart off cellular debris, and block invasion of a less benign population of inflammatory...
19-Oct-2015 4:05 PM EDT Add to Favorites

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