La Jolla Institute for Allergy and Immunology
La Jolla, CA USA
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The Innate Immune System Modulates the Severity of Multiple Sclerosis


Multiple sclerosis, a debilitating neurological disease, is triggered by self-reactive T cells that successfully infiltrate the brain and spinal cord where they launch an aggressive autoimmune attack against myelin, the fatty substance that...
28-Oct-2015 11:05 AM EDT Add to Favorites

A Subpopulation of White Blood Cells Guards Against Tumor Lung Metastasis


Among foot soldiers on the immune front line is a subpopulation of white blood cells called “patrolling monocytes,” whose job is to cruise the bloodstream, cart off cellular debris, and block invasion of a less benign population of inflammatory...
19-Oct-2015 4:05 PM EDT Add to Favorites

How to Become a T Follicular Helper Cell


Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the molecular signals that drive...
30-Jul-2015 4:05 PM EDT Add to Favorites

Keeping a Lid on Inflammation


Although critically important for shaping the immune response and maintaining self-tolerance, how regulatory T cells (Treg cells) hold on to their immune-suppressive powers had remained unclear. Now, for the first time, researchers at the La Jolla...
16-Jun-2015 4:05 PM EDT Add to Favorites

La Jolla Institute Scientists Reveal Potential New Drug Target for the Treatment of Rheumatoid Arthritis


Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are...
17-May-2015 7:00 PM EDT Add to Favorites

The Company You Keep

When fighting chronic viral infections or cancers, a key division of the immune system, known as CD8 T cells, sometimes loses its ability to effectively fight foreign invaders. Overcoming so-called T cell exhaustion is crucial to treating persistent...
12-Feb-2015 4:00 PM EST Add to Favorites

La Jolla Institute Scientist Receives $1.6 Million Research Grant From American Diabetes Association

The American Diabetes Association (ADA) has awarded La Jolla Institute (LJI) researcher Stephanie Stanford, Ph.D., a $1.6 million grant to investigate the genetic and environmental factors that trigger the onset of type 1 diabetes.
9-Jan-2015 8:15 AM EST Add to Favorites

La Jolla Institute Develops New Approach to Identify Genes Poised to Respond in Asthma Patients

In a study published yesterday in the scientific journal Nature Immunology, a group at the La Jolla Institute (LJI) led by Pandurangan Vijayanand, Ph.D. identify new genes that likely contribute to asthma, a disease that currently affects over 200...
8-Jul-2014 3:10 PM EDT Add to Favorites

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