La Jolla Institute for Allergy and Immunology
La Jolla, CA USA
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LJI Researchers Gain New Understanding of How Neutrophils Latch Onto Vessel Walls to Protect From Infection and Clean Up Injured Tissue


As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens. Neutrophils spend most of their lives racing through the bloodstream, patrolling for bacteria or other foreign...
31-Aug-2016 9:30 AM EDT Add to Favorites

Two LJI Scientists Selected to Join the Mucosal Immunology Studies Team (MIST)


The two teams will receive a total of more than $5 million to study immune defense mechanisms in the intestine.
19-Jul-2016 11:05 AM EDT Add to Favorites

LJI Researchers Reveal Dominant Player in Human T Helper Cell Maturation


A powerful arm of the immune system is production of antibodies that circulate through the blood and neutralize invading pathogens. Although B cells actually manufacture antibody proteins, the process is aided by neighboring T cells, which shower B...
30-Jun-2016 4:45 PM EDT Add to Favorites

LJI Scientists Discover Molecular Mechanism for Generating Specific Antibody Responses to Pathogens


LA JOLLA, CA—Follicular helper T cells (Tfh cells), a rare type of T cells, are indispensible for the maturation of antibody-producing B cells. They promote the proliferation of B cells that produce highly selective antibodies against invading...
2-May-2016 11:00 AM EDT Add to Favorites

New Findings in Humans Provide Encouraging Foundation for Upcoming AIDS Vaccine Clinical Trial


Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and scientists are working to develop a vaccine capable of inducing such “broadly neutralizing” antibodies that...
23-Mar-2016 2:00 PM EDT Add to Favorites

La Jolla Institute Receives $5 Million Gift From Pfizer

La Jolla Institute for Allergy and Immunology (LJI) has received a $5 million gift, which will help establish the Mission Support for Cancer Immunology and Oncology Research, the Institute announced today. The gift has been made by Pfizer Inc., one...
25-Feb-2016 10:50 AM EST Add to Favorites

Sharpin Emerges From the Pack as a Regulator of Inflammation


It is normal—in fact necessary—for our immune system to occasionally fly into an inflammatory rage to defend the host (us) against pathogens or even tumor cells. Problems arise when the rage persists or is re-directed against one’s self, as...
2-Feb-2016 11:05 AM EST Add to Favorites

New Study Indicates Why Children Are Likelier to Develop Food Allergies


An estimated 15 million Americans suffer from food allergies, many of them children. These are non-trivial concerns, as food allergy or intolerance can cause symptoms ranging from a harmless skin rash to a potentially lethal anaphylactic shock. The...
25-Jan-2016 11:05 AM EST Add to Favorites

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