La Jolla Institute for Allergy and Immunology
La Jolla, CA USA
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LJI Scientists Flip Molecular Switches to Distinguish Closely Related Immune Cell Populations


The cornerstone of genetics is the loss-of-function experiment. In short, this means that to figure out what exactly gene X is doing in a tissue of interest—be it developing brain cells or a pancreatic tumor—you somehow cut out, switch off or...
27-Oct-2016 12:35 PM EDT Add to Favorites

ZikaPLAN: La Jolla Institute Unites with 25 Research Organizations to Fight Zika Virus and Build Long-Term Outbreak Response Capacity in Latin America


La Jolla Institute for Allergy and Immunology (LJI) is among the 25 leading research and public health organizations from Latin America, North America, Africa, Asia, and Europe gathered in Recife for the launch of ZikaPLAN (Zika Preparedness Latin...
26-Oct-2016 12:35 PM EDT Add to Favorites

Zika Infection May Affect Adult Brain Cells, Suggesting Risk May Not Be Limited to Pregnant Women


Concerns over the Zika virus have focused on pregnant women due to mounting evidence that it causes brain abnormalities in developing fetuses. However, new research in mice from scientists at The Rockefeller University and La Jolla Institute for...
24-Oct-2016 11:20 AM EDT Add to Favorites

LJI Researchers Gain New Understanding of How Neutrophils Latch Onto Vessel Walls to Protect From Infection and Clean Up Injured Tissue


As an arm of the innate immune system, white blood cells called neutrophils form the first line of defense against invading pathogens. Neutrophils spend most of their lives racing through the bloodstream, patrolling for bacteria or other foreign...
31-Aug-2016 9:30 AM EDT Add to Favorites

Two LJI Scientists Selected to Join the Mucosal Immunology Studies Team (MIST)


The two teams will receive a total of more than $5 million to study immune defense mechanisms in the intestine.
19-Jul-2016 11:05 AM EDT Add to Favorites

LJI Researchers Reveal Dominant Player in Human T Helper Cell Maturation


A powerful arm of the immune system is production of antibodies that circulate through the blood and neutralize invading pathogens. Although B cells actually manufacture antibody proteins, the process is aided by neighboring T cells, which shower B...
30-Jun-2016 4:45 PM EDT Add to Favorites

LJI Scientists Discover Molecular Mechanism for Generating Specific Antibody Responses to Pathogens


LA JOLLA, CA—Follicular helper T cells (Tfh cells), a rare type of T cells, are indispensible for the maturation of antibody-producing B cells. They promote the proliferation of B cells that produce highly selective antibodies against invading...
2-May-2016 11:00 AM EDT Add to Favorites

New Findings in Humans Provide Encouraging Foundation for Upcoming AIDS Vaccine Clinical Trial


Some people infected with HIV naturally produce antibodies that effectively neutralize many strains of the rapidly mutating virus, and scientists are working to develop a vaccine capable of inducing such “broadly neutralizing” antibodies that...
23-Mar-2016 2:00 PM EDT Add to Favorites

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