La Jolla Institute for Allergy and Immunology
La Jolla, CA USA

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How to Become a T Follicular Helper Cell


Follicular helper Tcells (TFH cells), a rare type of immune cell that is essential for inducing a strong and lasting antibody response to viruses and other microbes, have garnered intense interest in recent years but the molecular signals that drive...
30-Jul-2015 4:05 PM EDT

Keeping a Lid on Inflammation


Although critically important for shaping the immune response and maintaining self-tolerance, how regulatory T cells (Treg cells) hold on to their immune-suppressive powers had remained unclear. Now, for the first time, researchers at the La Jolla...
16-Jun-2015 4:05 PM EDT

La Jolla Institute Scientists Reveal Potential New Drug Target for the Treatment of Rheumatoid Arthritis


Researchers at the La Jolla Institute for Allergy and Immunology, in collaboration with colleagues the University of California, San Diego, identified a novel drug target for the treatment of rheumatoid arthritis that focuses on the cells that are...
17-May-2015 7:00 PM EDT

The Company You Keep

When fighting chronic viral infections or cancers, a key division of the immune system, known as CD8 T cells, sometimes loses its ability to effectively fight foreign invaders. Overcoming so-called T cell exhaustion is crucial to treating persistent...
12-Feb-2015 4:00 PM EST

La Jolla Institute Scientist Receives $1.6 Million Research Grant From American Diabetes Association

The American Diabetes Association (ADA) has awarded La Jolla Institute (LJI) researcher Stephanie Stanford, Ph.D., a $1.6 million grant to investigate the genetic and environmental factors that trigger the onset of type 1 diabetes.
9-Jan-2015 8:15 AM EST

La Jolla Institute Develops New Approach to Identify Genes Poised to Respond in Asthma Patients

In a study published yesterday in the scientific journal Nature Immunology, a group at the La Jolla Institute (LJI) led by Pandurangan Vijayanand, Ph.D. identify new genes that likely contribute to asthma, a disease that currently affects over 200...
8-Jul-2014 3:10 PM EDT

La Jolla Institute Advances Research Toward World’s First Vaccine for Heart Disease

Research toward the world’s first vaccine for heart disease continues to advance at the La Jolla Institute for Allergy and Immunology, with researchers demonstrating significant arterial plaque reduction in concept testing in mice.
17-Jun-2014 6:00 AM EDT

La Jolla Institute Discovers New Mechanism for Unleashing Immune System Against Cancer

A major discovery that brings a new drug target to the increasingly exciting landscape of cancer immunotherapy was published yesterday by researchers from La Jolla Institute for Allergy and Immunology and their collaborators from other institutes.
3-Apr-2014 3:00 PM EDT

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