La Jolla Institute for Allergy and Immunology
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TWEAKing Inflammation


Superficially, psoriasis and atopic dermatitis may appear similar but their commonalities are only skin deep. Atopic dermatitis, also known as eczema, is primarily driven by an allergic reaction, while psoriasis is considered an autoimmune disease....
18-May-2017 10:05 AM EDT Add to Favorites

LJI Professor Klaus Ley Wins Prestigious National Award


Professor Klaus Ley, M.D., has been selected as this year’s winner of the Eugene M. Landis Award, the Microcirculatory Society’s top honor, in recognition of his pioneering work in vascular biology and microcirculation. The microcirculation...
24-Apr-2017 10:05 AM EDT Add to Favorites

LJI Research Lab Wins Best Academic Research Team Award

Dr. Alessandro Sette’s team at La Jolla Institute for Allergy and Immunology has been named Best Academic Research Team as part of the 10th Vaccine Industry Excellence Awards at this year’s World Vaccine Congress 2017 held in Washington. The ViE...
14-Apr-2017 12:05 PM EDT Add to Favorites

The Molecular Underpinnings of T Cell Exhaustion


One reason we survive into adulthood is that cell-killing T cells usually recognize and eliminate cancerous or pathogen-infected cells. But prolonged overactivity of immune cells summoned to a tumor or infection site can render them useless to...
14-Mar-2017 10:20 AM EDT Add to Favorites

Pre-Existing Immunity to Dengue Virus Shapes Zika-Specific T Cell Response


Although Zika and dengue are considered different virus “species,” they are so closely related that the immune system treats Zika just like another version of dengue, report researchers at La Jolla Institute for Allergy and Immunology. Their...
10-Mar-2017 4:15 PM EST Add to Favorites

T Cells Join the Fight Against Zika


The worst of the global Zika virus outbreak may be over but many key questions remain, such as why the virus persists in certain tissues after the systemic infection has cleared; how does the immune system counteract the virus and protect against...
12-Jan-2017 9:05 AM EST Add to Favorites

LJI Researchers Strengthen the Case for Sexual Transmission of Zika Virus


Aedes aegypti mosquitoes harboring parasitic Zika virus (ZIKV) are the primary transmitters of virus to humans, potentially causing catastrophic congenital microcephaly in babies born to women bitten by infected mosquitoes. But confirmation earlier...
15-Dec-2016 9:40 AM EST Add to Favorites

Exhausted T cells


In a bid to better understand the gene expression patterns that control T cell activity, researchers at the La Jolla Institute for Allergy and Immunology mapped genome-wide changes in chromatin accessibility as T cells respond to acute and chronic...
19-Dec-2016 1:05 PM EST Add to Favorites

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