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Drug Combination Targeting Heat Shock Protein 90 and BRAF is Safe and Effective in Advanced Melanoma Patients

TAMPA, Fla. – Patients with advanced or metastatic melanoma have been able to live longer cancer-free lives because of several new therapies approved over the last decade, such as BRAF and MEK inhibitors. However, despite the success of these...
19-Apr-2018 10:05 AM EDT Add to Favorites

Mathematical Modeling Offers New Way to Understand Variable Responses to Targeted Therapy

Cancer therapies that target a specific protein have improved outcomes for patients. However, many patients eventually develop resistance to these targeted therapies and their cancer comes back. It is believed that differences among tumor cells, or...
3-Apr-2018 10:05 AM EDT Add to Favorites

Screening High-Risk Individuals Can Reduce Multiple Myeloma Mortality

TAMPA, Fla. – Multiple myeloma is a rare incurable disease that is diagnosed in more than 30,000 people each year in the United States.  Only half of patients with multiple myeloma are expected to survive five years after their diagnosis. Moffitt...
27-Mar-2018 8:05 AM EDT Add to Favorites

Moffitt Researchers Use Single-Cell Imaging and Mathematical Modeling to Determine Effective Drug Properties

Drug therapies that target a specific molecule have changed the way patients are treated for cancer and greatly improved survival rates. However, some patients do not respond to these therapies because the drug is not reaching the tumor cells...
13-Mar-2018 9:00 AM EDT Add to Favorites

Moffitt Researchers Identify New Target to Reduce Risk of Graft-Versus-Host Disease

Moffitt Cancer Center researchers are trying to identify new drug targets to reduce the risk of GVHD. Their new study, published in the Proceedings of the National Academy of Sciences, shows a drug that targets the protein JAK2 may reduce the risk...
5-Feb-2018 11:05 AM EST Add to Favorites

Moffitt Researchers Discover New Approach to Stimulate an Immune Response Against Tumor Cells

New drugs that activate the immune system to target cancer cells have improved the lives of many patients with cancer. However, immunotherapies are not effective in all patients, and the success of these therapies depends on individual patient...
30-Jan-2018 9:05 AM EST Add to Favorites

Rare Melanoma Type Highly Responsive to Immunotherapy

Desmoplastic melanoma is a rare subtype of melanoma that is commonly found on sun-exposed areas, such as the head and neck, and usually seen in older patients. Treatment is difficult because these tumors are often resistant to chemotherapy and lack...
10-Jan-2018 2:05 PM EST Add to Favorites

Men, If You Have HPV, Odds Are You Will Be Reinfected with the Same Type

Men infected with HPV16, the type responsible for most HPV-related cancers, are 20 times more likely to be reinfected with the same type of HPV after one year. That is according to a new study published this month in the Proceedings of the National...
14-Dec-2017 1:05 PM EST Add to Favorites

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Moffitt Cancer Center HPV Expert Kicked Off EUROGIN Conference

Anna Giuliano, Ph.D., director of Moffitt Cancer Center’s Center for Infection Research in Cancer, delivered the opening keynote address at the 2017 European Research Organization on Genital Infection and Neoplasia (EUROGIN) International...
10-Oct-2017 10:05 AM EDT

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